3wjx - Revision history

OCA at 13:13, 8 November 2023

OCA — Wed, 08 Nov 2023 13:13:15 GMT

←Older revision		Revision as of 13:13, 8 November 2023
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	<StructureSection load='3wjx' size='340' side='right'caption='[[3wjx]], [[Resolution\|resolution]] 1.23Å' scene=''>		<StructureSection load='3wjx' size='340' side='right'caption='[[3wjx]], [[Resolution\|resolution]] 1.23Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3wjx]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Metth Metth~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WJX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3WJX FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3wjx]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Methanothermobacter_thermautotrophicus_str._Delta_H Methanothermobacter thermautotrophicus str. Delta H]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WJX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3WJX FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>~~, ~~<scene name='pdbligand=NUP:6-AMINOURIDINE+5-MONOPHOSPHATE'>NUP</scene></td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.23Å</td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>~~[[~~Related_structure~~\|~~Related:~~]]~~</b></td><td class="sblockDat"><div style='overflow: auto~~; ~~max-height: 3em;'>[[3wjw\|3wjw]], [[3wjy\|3wjy]], [[3wjz\|3wjz]], [[3wk0\|3wk0]], [[3wk1\|3wk1]], [[3wk2\|3wk2]], [[3wk3\|3wk3]]</div>~~</td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NUP:6-AMINOURIDINE+5-MONOPHOSPHATE'>NUP</scene></td></tr>
-	<tr id='~~gene~~'><td class="sblockLbl"><b>[[~~Gene~~\|~~Gene~~:]]</b></td><td class="sblockDat"~~>pyrF, MTH_129 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&~~id=~~187420 METTH])</td~~><~~/tr>~~	+
-	~~<tr id~~='~~activity'><td class~~=~~"sblockLbl"><b>Activity~~:~~</b~~></td><~~td class~~=~~"sblockDat"><span class~~=~~'plainlinks'>[https~~:~~//en.wikipedia.org/wiki/Orotidine~~-5'-~~phosphate_decarboxylase Orotidine-5~~'~~-phosphate decarboxylase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.23 4.1.1.23]~~ </~~span~~></td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3wjx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wjx OCA], [https://pdbe.org/3wjx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3wjx RCSB], [https://www.ebi.ac.uk/pdbsum/3wjx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3wjx ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3wjx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wjx OCA], [https://pdbe.org/3wjx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3wjx RCSB], [https://www.ebi.ac.uk/pdbsum/3wjx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3wjx ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/PYRF_METTH PYRF_METTH]] Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).[HAMAP-Rule:MF_01200_A]	+	[https://www.uniprot.org/uniprot/PYRF_METTH PYRF_METTH] Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).[HAMAP-Rule:MF_01200_A]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Metth]]~~	+	[[Category: Methanothermobacter thermautotrophicus str. Delta H]]
-	~~[[Category: Orotidine-5'-phosphate decarboxylase~~]]	+	[[Category: Fujihashi M]]
-	[[Category: Fujihashi, M]]	+	[[Category: Kuroda S]]
-	[[Category: Kuroda, S]]	+	[[Category: Miki K]]
-	[[Category: Miki, K]]	+	[[Category: Pai EF]]
-	[[Category: Pai~~, E F]]~~	+
-	~~[[Category: Decarboxylase]]~~	+
-	~~[[Category: Lyase]]~~	+
-	~~[[Category: Protein-ligand complex]]~~	+
-	~~[[Category: Pyrimidine biosynthesis]]~~	+
-	~~[[Category: Tim barrel~~]]	+

OCA at 05:39, 3 August 2022

OCA — Wed, 03 Aug 2022 05:39:24 GMT

←Older revision		Revision as of 05:39, 3 August 2022
Line 1:		Line 1:

	==Wild-type orotidine 5'-monophosphate decarboxylase from M. thermoautotrophicus complexed with 6-amino-UMP==		==Wild-type orotidine 5'-monophosphate decarboxylase from M. thermoautotrophicus complexed with 6-amino-UMP==
-	<StructureSection load='3wjx' size='340' side='right' caption='[[3wjx]], [[Resolution\|resolution]] 1.23Å' scene=''>	+	<StructureSection load='3wjx' size='340' side='right'caption='[[3wjx]], [[Resolution\|resolution]] 1.23Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3wjx]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Metth Metth]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WJX OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3WJX FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3wjx]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Metth Metth]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WJX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3WJX FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NUP:6-AMINOURIDINE+5-MONOPHOSPHATE'>NUP</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NUP:6-AMINOURIDINE+5-MONOPHOSPHATE'>NUP</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3wjw\|3wjw]], [[3wjy\|3wjy]], [[3wjz\|3wjz]], [[3wk0\|3wk0]], [[3wk1\|3wk1]], [[3wk2\|3wk2]], [[3wk3\|3wk3]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3wjw\|3wjw]], [[3wjy\|3wjy]], [[3wjz\|3wjz]], [[3wk0\|3wk0]], [[3wk1\|3wk1]], [[3wk2\|3wk2]], [[3wk3\|3wk3]]</div></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">pyrF, MTH_129 ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=187420 METTH])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">pyrF, MTH_129 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=187420 METTH])</td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/Orotidine-5'-phosphate_decarboxylase Orotidine-5'-phosphate decarboxylase], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.23 4.1.1.23] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Orotidine-5'-phosphate_decarboxylase Orotidine-5'-phosphate decarboxylase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.23 4.1.1.23] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3wjx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wjx OCA], [~~http~~://pdbe.org/3wjx PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3wjx RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3wjx PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3wjx ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3wjx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wjx OCA], [https://pdbe.org/3wjx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3wjx RCSB], [https://www.ebi.ac.uk/pdbsum/3wjx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3wjx ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/PYRF_METTH PYRF_METTH]] Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).[HAMAP-Rule:MF_01200_A]	+	[[https://www.uniprot.org/uniprot/PYRF_METTH PYRF_METTH]] Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).[HAMAP-Rule:MF_01200_A]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 21:		Line 21:
	</div>		</div>
	<div class="pdbe-citations 3wjx" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 3wjx" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Uridine 5'-monophosphate synthase 3D structures\|Uridine 5'-monophosphate synthase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Metth]]		[[Category: Metth]]
	[[Category: Orotidine-5'-phosphate decarboxylase]]		[[Category: Orotidine-5'-phosphate decarboxylase]]

OCA at 04:42, 5 August 2016

OCA — Fri, 05 Aug 2016 04:42:32 GMT

←Older revision		Revision as of 04:42, 5 August 2016
Line 1:		Line 1:
		+
	==Wild-type orotidine 5'-monophosphate decarboxylase from M. thermoautotrophicus complexed with 6-amino-UMP==		==Wild-type orotidine 5'-monophosphate decarboxylase from M. thermoautotrophicus complexed with 6-amino-UMP==
	<StructureSection load='3wjx' size='340' side='right' caption='[[3wjx]], [[Resolution\|resolution]] 1.23Å' scene=''>		<StructureSection load='3wjx' size='340' side='right' caption='[[3wjx]], [[Resolution\|resolution]] 1.23Å' scene=''>
Line 7:		Line 8:
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">pyrF, MTH_129 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=187420 METTH])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">pyrF, MTH_129 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=187420 METTH])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Orotidine-5'-phosphate_decarboxylase Orotidine-5'-phosphate decarboxylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.23 4.1.1.23] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Orotidine-5'-phosphate_decarboxylase Orotidine-5'-phosphate decarboxylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.23 4.1.1.23] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3wjx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wjx OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3wjx RCSB], [http://www.ebi.ac.uk/pdbsum/3wjx PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3wjx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wjx OCA], [http://pdbe.org/3wjx PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3wjx RCSB], [http://www.ebi.ac.uk/pdbsum/3wjx PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3wjx ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 19:		Line 20:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3wjx" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 23:03, 24 December 2014

OCA — Wed, 24 Dec 2014 23:03:31 GMT

←Older revision		Revision as of 23:03, 24 December 2014
Line 9:		Line 9:
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3wjx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wjx OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3wjx RCSB], [http://www.ebi.ac.uk/pdbsum/3wjx PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3wjx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wjx OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3wjx RCSB], [http://www.ebi.ac.uk/pdbsum/3wjx PDBsum]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/PYRF_METTH PYRF_METTH]] Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).[HAMAP-Rule:MF_01200_A]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==

OCA at 18:29, 21 December 2014

OCA — Sun, 21 Dec 2014 18:29:06 GMT

←Older revision		Revision as of 18:29, 21 December 2014
Line 1:		Line 1:
-	~~{{STRUCTURE_3wjx\| PDB=3wjx \| SCENE= }}~~	+	==Wild-type orotidine 5'-monophosphate decarboxylase from M. thermoautotrophicus complexed with 6-amino-UMP==
-	===Wild-type orotidine 5'-monophosphate decarboxylase from M. thermoautotrophicus complexed with 6-amino-UMP===	+	<StructureSection load='3wjx' size='340' side='right' caption='[[3wjx]], [[Resolution\|resolution]] 1.23Å' scene=''>
-	~~{{ABSTRACT_PUBMED_24151964}}~~	+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[3wjx]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Metth Metth]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WJX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3WJX FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NUP:6-AMINOURIDINE+5-MONOPHOSPHATE'>NUP</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3wjw\|3wjw]], [[3wjy\|3wjy]], [[3wjz\|3wjz]], [[3wk0\|3wk0]], [[3wk1\|3wk1]], [[3wk2\|3wk2]], [[3wk3\|3wk3]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">pyrF, MTH_129 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=187420 METTH])</td></tr>
		+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Orotidine-5'-phosphate_decarboxylase Orotidine-5'-phosphate decarboxylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.23 4.1.1.23] </span></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3wjx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wjx OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3wjx RCSB], [http://www.ebi.ac.uk/pdbsum/3wjx PDBsum]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Orotidine 5'-monophosphate decarboxylase (ODCase) accelerates the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP) by 17 orders of magnitude. Eight new crystal structures with ligand analogues combined with computational analyses of the enzyme's short-lived intermediates and the intrinsic electronic energies to distort the substrate and other ligands improve our understanding of the still controversially discussed reaction mechanism. In their respective complexes, 6-methyl-UMP displays significant distortion of its methyl substituent bond, 6-amino-UMP shows the competition between the K72 and C6 substituents for a position close to D70, and the methyl and ethyl esters of OMP both induce rotation of the carboxylate group substituent out of the plane of the pyrimidine ring. Molecular dynamics and quantum mechanics/molecular mechanics computations of the enzyme-substrate complex also show the bond between the carboxylate group and the pyrimidine ring to be distorted, with the distortion contributing a 10-15% decrease of the DeltaDeltaG() value. These results are consistent with ODCase using both substrate distortion and transition-state stabilization, primarily exerted by K72, in its catalysis of the OMP decarboxylation reaction.

-	~~==Function==~~	+	Substrate distortion contributes to the catalysis of orotidine 5'-monophosphate decarboxylase.,Fujihashi M, Ishida T, Kuroda S, Kotra LP, Pai EF, Miki K J Am Chem Soc. 2013 Nov 20;135(46):17432-43. doi: 10.1021/ja408197k. Epub 2013, Nov 11. PMID:24151964<ref>PMID:24151964</ref>
-	~~[[http://www.uniprot.org/uniprot/PYRF_METTH PYRF_METTH]] Catalyzes~~ the ~~decarboxylation~~ of orotidine 5'-monophosphate (~~OMP~~) ~~to uridine 5'~~-~~monophosphate (UMP)~~.~~[HAMAP-Rule~~:~~MF_01200_A]~~	+

-	~~==About this Structure==~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	~~[[3wjx]] is~~ a ~~1 chain structure~~. ~~Full crystallographic information is available from [http://oca~~.~~weizmann~~.~~ac.il~~/~~oca-bin/ocashort?id=3WJX OCA].~~	+	</div>
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	~~<ref group="xtra">PMID:024151964</ref>~~<references ~~group="xtra"~~/><~~references~~/>	+	__TOC__
		+	</StructureSection>
		+	[[Category: Metth]]
	[[Category: Orotidine-5'-phosphate decarboxylase]]		[[Category: Orotidine-5'-phosphate decarboxylase]]
-	[[Category: Fujihashi, M.]]	+	[[Category: Fujihashi, M]]
-	[[Category: Kuroda, S.]]	+	[[Category: Kuroda, S]]
-	[[Category: Miki, K.]]	+	[[Category: Miki, K]]
-	[[Category: Pai, E F.]]	+	[[Category: Pai, E F]]
	[[Category: Decarboxylase]]		[[Category: Decarboxylase]]
	[[Category: Lyase]]		[[Category: Lyase]]

OCA at 07:22, 4 December 2013

OCA — Wed, 04 Dec 2013 07:22:10 GMT

←Older revision		Revision as of 07:22, 4 December 2013
Line 1:		Line 1:
-	'~~''Unreleased structure'''~~	+	{{STRUCTURE_3wjx\| PDB=3wjx \| SCENE= }}
		+	===Wild-type orotidine 5'-monophosphate decarboxylase from M. thermoautotrophicus complexed with 6-amino-UMP===
		+	{{ABSTRACT_PUBMED_24151964}}

-	~~The entry 3wjx is ON HOLD until Paper Publication~~	+	==Function==
		+	[[http://www.uniprot.org/uniprot/PYRF_METTH PYRF_METTH]] Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).[HAMAP-Rule:MF_01200_A]

-	~~Authors: Fujihashi, M~~.~~, Kuroda, S~~.~~, Pai, E~~.F.~~, Miki, K~~.	+	==About this Structure==
		+	[[3wjx]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WJX OCA].

-	~~Description~~: ~~Wild~~-~~type orotidine~~ 5'-~~monophosphate~~ decarboxylase ~~from~~ M. ~~thermoautotrophicus complexed with 6~~-~~amino-UMP~~	+	==Reference==
		+	<ref group="xtra">PMID:024151964</ref><references group="xtra"/><references/>
		+	[[Category: Orotidine-5'-phosphate decarboxylase]]
		+	[[Category: Fujihashi, M.]]
		+	[[Category: Kuroda, S.]]
		+	[[Category: Miki, K.]]
		+	[[Category: Pai, E F.]]
		+	[[Category: Decarboxylase]]
		+	[[Category: Lyase]]
		+	[[Category: Protein-ligand complex]]
		+	[[Category: Pyrimidine biosynthesis]]
		+	[[Category: Tim barrel]]

OCA at 12:32, 20 November 2013

OCA — Wed, 20 Nov 2013 12:32:15 GMT

←Older revision		Revision as of 12:32, 20 November 2013
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 3wjx is ON HOLD	+	The entry 3wjx is ON HOLD until Paper Publication

	Authors: Fujihashi, M., Kuroda, S., Pai, E.F., Miki, K.		Authors: Fujihashi, M., Kuroda, S., Pai, E.F., Miki, K.

	Description: Wild-type orotidine 5'-monophosphate decarboxylase from M. thermoautotrophicus complexed with 6-amino-UMP		Description: Wild-type orotidine 5'-monophosphate decarboxylase from M. thermoautotrophicus complexed with 6-amino-UMP

OCA: Protected "3wjx" [edit=sysop:move=sysop]

OCA — Wed, 23 Oct 2013 05:34:10 GMT

Protected "3wjx" [edit=sysop:move=sysop]

←Older revision

Revision as of 05:34, 23 October 2013

OCA: New page: '''Unreleased structure''' The entry 3wjx is ON HOLD Authors: Fujihashi, M., Kuroda, S., Pai, E.F., Miki, K. Description: Wild-type orotidine 5'-monophosphate decarboxylase from M. the...

OCA — Wed, 23 Oct 2013 05:34:10 GMT

New page: '''Unreleased structure''' The entry 3wjx is ON HOLD Authors: Fujihashi, M., Kuroda, S., Pai, E.F., Miki, K. Description: Wild-type orotidine 5'-monophosphate decarboxylase from M. the...

New page

'''Unreleased structure'''

The entry 3wjx is ON HOLD

Authors: Fujihashi, M., Kuroda, S., Pai, E.F., Miki, K.

Description: Wild-type orotidine 5'-monophosphate decarboxylase from M. thermoautotrophicus complexed with 6-amino-UMP