3wkz - Revision history

OCA at 13:13, 8 November 2023

OCA — Wed, 08 Nov 2023 13:13:54 GMT

←Older revision		Revision as of 13:13, 8 November 2023
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	<StructureSection load='3wkz' size='340' side='right'caption='[[3wkz]], [[Resolution\|resolution]] 2.00Å' scene=''>		<StructureSection load='3wkz' size='340' side='right'caption='[[3wkz]], [[Resolution\|resolution]] 2.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3wkz]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Asian_corn_borer Asian corn borer~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WKZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3WKZ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3wkz]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Ostrinia_furnacalis Ostrinia furnacalis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WKZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3WKZ FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=NAG:N~~-~~ACETYL-D-GLUCOSAMINE'>NAG</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.001Å</td></tr>
-	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"~~><div style='overflow: auto; max-height: 3em;'>[[3wl0\|3wl0]], [[3wl1\|3wl1]]</div></td></tr>~~	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
-	~~<tr~~ id~~='activity'><td class~~="~~sblockLbl~~"><~~b>Activity:</b></td><td class~~=~~"sblockDat"><span class~~=~~'plainlinks~~'>~~[https://en.wikipedia.org/wiki/Chitinase Chitinase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.14 3.2.1.14]~~ </~~span~~></td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3wkz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wkz OCA], [https://pdbe.org/3wkz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3wkz RCSB], [https://www.ebi.ac.uk/pdbsum/3wkz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3wkz ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3wkz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wkz OCA], [https://pdbe.org/3wkz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3wkz RCSB], [https://www.ebi.ac.uk/pdbsum/3wkz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3wkz ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/Q2V6H4_OSTFU Q2V6H4_OSTFU]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Asian corn borer]]
-	[[Category: Chitinase]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Chen, L]]	+	[[Category: Ostrinia furnacalis]]
-	[[Category: Chen, Q]]	+	[[Category: Chen L]]
-	[[Category: Liu, T]]	+	[[Category: Chen Q]]
-	[[Category: Shen, X]]	+	[[Category: Liu T]]
-	[[Category: Yang, Q]]	+	[[Category: Shen X]]
-	[[Category: Zhou, Y]]	+	[[Category: Yang Q]]
-	~~[[Category: Glycosyl hydrolase]]~~	+	[[Category: Zhou Y]]
-	~~[[Category: Hydrolase]]~~	+
-	~~[[Category: Insect]]~~	+
-	~~[[Category: Ostrinia furnacali~~]]	+

OCA at 05:40, 3 August 2022

OCA — Wed, 03 Aug 2022 05:40:42 GMT

←Older revision		Revision as of 05:40, 3 August 2022
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	==Crystal Structure of the Ostrinia furnacalis Group I Chitinase catalytic domain E148Q mutant==		==Crystal Structure of the Ostrinia furnacalis Group I Chitinase catalytic domain E148Q mutant==
-	<StructureSection load='3wkz' size='340' side='right' caption='[[3wkz]], [[Resolution\|resolution]] 2.00Å' scene=''>	+	<StructureSection load='3wkz' size='340' side='right'caption='[[3wkz]], [[Resolution\|resolution]] 2.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3wkz]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Asian_corn_borer Asian corn borer]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WKZ OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3WKZ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3wkz]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Asian_corn_borer Asian corn borer]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WKZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3WKZ FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3wl0\|3wl0]], [[3wl1\|3wl1]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3wl0\|3wl0]], [[3wl1\|3wl1]]</div></td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/Chitinase Chitinase], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.14 3.2.1.14] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Chitinase Chitinase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.14 3.2.1.14] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3wkz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wkz OCA], [~~http~~://pdbe.org/3wkz PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3wkz RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3wkz PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3wkz ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3wkz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wkz OCA], [https://pdbe.org/3wkz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3wkz RCSB], [https://www.ebi.ac.uk/pdbsum/3wkz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3wkz ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 20:		Line 20:

	==See Also==		==See Also==
-	*[[Chitinase\|Chitinase]]	+	*[[Chitinase 3D structures\|Chitinase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 27:		Line 27:
	[[Category: Asian corn borer]]		[[Category: Asian corn borer]]
	[[Category: Chitinase]]		[[Category: Chitinase]]
		+	[[Category: Large Structures]]
	[[Category: Chen, L]]		[[Category: Chen, L]]
	[[Category: Chen, Q]]		[[Category: Chen, Q]]

OCA at 17:24, 18 January 2017

OCA — Wed, 18 Jan 2017 17:24:12 GMT

←Older revision		Revision as of 17:24, 18 January 2017
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		+
	==Crystal Structure of the Ostrinia furnacalis Group I Chitinase catalytic domain E148Q mutant==		==Crystal Structure of the Ostrinia furnacalis Group I Chitinase catalytic domain E148Q mutant==
	<StructureSection load='3wkz' size='340' side='right' caption='[[3wkz]], [[Resolution\|resolution]] 2.00Å' scene=''>		<StructureSection load='3wkz' size='340' side='right' caption='[[3wkz]], [[Resolution\|resolution]] 2.00Å' scene=''>
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	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3wl0\|3wl0]], [[3wl1\|3wl1]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3wl0\|3wl0]], [[3wl1\|3wl1]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Chitinase Chitinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.14 3.2.1.14] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Chitinase Chitinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.14 3.2.1.14] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3wkz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wkz OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3wkz RCSB], [http://www.ebi.ac.uk/pdbsum/3wkz PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3wkz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wkz OCA], [http://pdbe.org/3wkz PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3wkz RCSB], [http://www.ebi.ac.uk/pdbsum/3wkz PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3wkz ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 16:		Line 17:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3wkz" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==

OCA at 06:41, 15 April 2015

OCA — Wed, 15 Apr 2015 06:41:57 GMT

←Older revision		Revision as of 06:41, 15 April 2015
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	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3wkz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wkz OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3wkz RCSB], [http://www.ebi.ac.uk/pdbsum/3wkz PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3wkz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wkz OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3wkz RCSB], [http://www.ebi.ac.uk/pdbsum/3wkz PDBsum]</span></td></tr>
	</table>		</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Insects possess a greater number of chitinases than any other organisms. This work is the first report of unliganded and oligosaccharide-complexed crystal structures of the insect chitinase OfChtI from Ostrinia furnacalis, which is essential to moulting. The obtained crystal structures were solved at resolutions between 1.7 and 2.2 A. A structural comparison with other chitinases revealed that OfChtI contains a long substrate-binding cleft similar to the bacterial chitinase SmChiB from Serratia marcescens. However, unlike the exo-acting SmChiB, which has a blocked and tunnel-like cleft, OfChtI possesses an open and groove-like cleft. The complexed structure of the catalytic domain of OfChtI (OfChtI-CAD) with (GlcNAc)2/3 indicates that the reducing sugar at subsite -1 is in an energetically unfavoured `boat' conformation, a state that possibly exists just before the completion of catalysis. Because OfChtI is known to act from nonreducing ends, (GlcNAc)3 would be a hydrolysis product of (GlcNAc)6, suggesting that OfChtI possesses an endo enzymatic activity. Furthermore, a hydrophobic plane composed of four surface-exposed aromatic residues is adjacent to the entrance to the substrate-binding cleft. Mutations of these residues greatly impair the chitin-binding activity, indicating that this hydrophobic plane endows OfChtI-CAD with the ability to anchor chitin. This work reveals the unique structural characteristics of an insect chitinase.
		+
		+	Structural characteristics of an insect group I chitinase, an enzyme indispensable to moulting.,Chen L, Liu T, Zhou Y, Chen Q, Shen X, Yang Q Acta Crystallogr D Biol Crystallogr. 2014 Apr 1;70(Pt 4):932-42. doi:, 10.1107/S1399004713033841. Epub 2014 Mar 19. PMID:24699639<ref>PMID:24699639</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+
		+	==See Also==
		+	*[[Chitinase\|Chitinase]]
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>

OCA at 09:19, 25 January 2015

OCA — Sun, 25 Jan 2015 09:19:23 GMT

←Older revision		Revision as of 09:19, 25 January 2015
Line 1:		Line 1:
-	~~{{STRUCTURE_3wkz\| PDB=3wkz \| SCENE= }}~~	+	==Crystal Structure of the Ostrinia furnacalis Group I Chitinase catalytic domain E148Q mutant==
-	===Crystal Structure of the Ostrinia furnacalis Group I Chitinase catalytic domain E148Q mutant===	+	<StructureSection load='3wkz' size='340' side='right' caption='[[3wkz]], [[Resolution\|resolution]] 2.00Å' scene=''>
-		+	== Structural highlights ==
-	==~~About this Structure~~==	+	<table><tr><td colspan='2'>[[3wkz]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Asian_corn_borer Asian corn borer]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WKZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3WKZ FirstGlance]. <br>
-	[[3wkz]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WKZ OCA].	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3wl0\|3wl0]], [[3wl1\|3wl1]]</td></tr>
		+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Chitinase Chitinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.14 3.2.1.14] </span></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3wkz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wkz OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3wkz RCSB], [http://www.ebi.ac.uk/pdbsum/3wkz PDBsum]</span></td></tr>
		+	</table>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Asian corn borer]]
	[[Category: Chitinase]]		[[Category: Chitinase]]
-	[[Category: Chen, L.]]	+	[[Category: Chen, L]]
-	[[Category: Chen, Q.]]	+	[[Category: Chen, Q]]
-	[[Category: Liu, T.]]	+	[[Category: Liu, T]]
-	[[Category: Shen, X.]]	+	[[Category: Shen, X]]
-	[[Category: Yang, Q.]]	+	[[Category: Yang, Q]]
-	[[Category: Zhou, Y.]]	+	[[Category: Zhou, Y]]
	[[Category: Glycosyl hydrolase]]		[[Category: Glycosyl hydrolase]]
	[[Category: Hydrolase]]		[[Category: Hydrolase]]
	[[Category: Insect]]		[[Category: Insect]]
	[[Category: Ostrinia furnacali]]		[[Category: Ostrinia furnacali]]

OCA at 06:37, 9 April 2014

OCA — Wed, 09 Apr 2014 06:37:48 GMT

←Older revision		Revision as of 06:37, 9 April 2014
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	{{STRUCTURE_3wkz\| PDB=3wkz \| SCENE= }}
		+	===Crystal Structure of the Ostrinia furnacalis Group I Chitinase catalytic domain E148Q mutant===

-	~~The entry~~ 3wkz is ~~ON HOLD until Paper Publication~~	+	==About this Structure==
-		+	[[3wkz]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WKZ OCA].
-	~~Authors~~: Chen, L.~~, Liu, T., Zhou, Y.,~~ Chen, Q., Shen, X., Yang, Q.	+	[[Category: Chitinase]]
-		+	[[Category: Chen, L.]]
-	~~Description~~: ~~Crystal Structure of the~~ Ostrinia ~~furnacalis Group I Chitinase catalytic domain E148Q mutant~~	+	[[Category: Chen, Q.]]
		+	[[Category: Liu, T.]]
		+	[[Category: Shen, X.]]
		+	[[Category: Yang, Q.]]
		+	[[Category: Zhou, Y.]]
		+	[[Category: Glycosyl hydrolase]]
		+	[[Category: Hydrolase]]
		+	[[Category: Insect]]
		+	[[Category: Ostrinia furnacali]]

OCA at 12:32, 20 November 2013

OCA — Wed, 20 Nov 2013 12:32:49 GMT

←Older revision		Revision as of 12:32, 20 November 2013
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 3wkz is ON HOLD	+	The entry 3wkz is ON HOLD until Paper Publication

-	Authors: Chen,L, Liu,T, Zhou,Y, Chen,Q, Shen,X, Yang,Q	+	Authors: Chen, L., Liu, T., Zhou, Y., Chen, Q., Shen, X., Yang, Q.

-	Description: Crystal Structure of the of Ostrinia furnacalis Group I Chitinase catalytic domain E148Q mutant	+	Description: Crystal Structure of the Ostrinia furnacalis Group I Chitinase catalytic domain E148Q mutant

OCA: Protected "3wkz" [edit=sysop:move=sysop]

OCA — Wed, 13 Nov 2013 07:07:12 GMT

Protected "3wkz" [edit=sysop:move=sysop]

←Older revision

Revision as of 07:07, 13 November 2013

OCA: New page: '''Unreleased structure''' The entry 3wkz is ON HOLD Authors: Chen,L, Liu,T, Zhou,Y, Chen,Q, Shen,X, Yang,Q Description: Crystal Structure of the of Ostrinia furnacalis Group I Chitina...

OCA — Wed, 13 Nov 2013 07:07:11 GMT

New page: '''Unreleased structure''' The entry 3wkz is ON HOLD Authors: Chen,L, Liu,T, Zhou,Y, Chen,Q, Shen,X, Yang,Q Description: Crystal Structure of the of Ostrinia furnacalis Group I Chitina...

New page

'''Unreleased structure'''

The entry 3wkz is ON HOLD

Authors: Chen,L, Liu,T, Zhou,Y, Chen,Q, Shen,X, Yang,Q

Description: Crystal Structure of the of Ostrinia furnacalis Group I Chitinase catalytic domain E148Q mutant