3wla - Revision history

OCA at 13:14, 8 November 2023

OCA — Wed, 08 Nov 2023 13:14:39 GMT

←Older revision		Revision as of 13:14, 8 November 2023
Line 3:		Line 3:
	<StructureSection load='3wla' size='340' side='right'caption='[[3wla]], [[Resolution\|resolution]] 1.90Å' scene=''>		<StructureSection load='3wla' size='340' side='right'caption='[[3wla]], [[Resolution\|resolution]] 1.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3wla]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Sphs1 Sphs1~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WLA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3WLA FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3wla]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Sphingopyxis_sp._113P3 Sphingopyxis sp. 113P3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WLA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3WLA FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.9Å</td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max~~-~~height: 3em;'>[[3wl5\|3wl5]]~~, [[~~3wl6~~\|~~3wl6]], [[3wl7\|3wl7]], [[3wl8\|3wl8~~]]~~</div>~~</td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	<tr id='~~gene~~'><td class="sblockLbl"><b>[[~~Gene~~\|~~Gene~~:]]</b></td><td class="sblockDat"~~>oph ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&~~id=~~292913 SPHS1])</td~~><~~/tr>~~	+
-	~~<tr id~~='~~activity'><td class~~=~~"sblockLbl"><b>Activity~~:~~</b></td><td class="sblockDat"><span class='plainlinks~~'>~~[https://en.wikipedia.org/wiki/Beta-diketone_hydrolase Beta-diketone hydrolase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.7.1.7 3.7.1.7]~~ </~~span~~></td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3wla FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wla OCA], [https://pdbe.org/3wla PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3wla RCSB], [https://www.ebi.ac.uk/pdbsum/3wla PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3wla ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3wla FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wla OCA], [https://pdbe.org/3wla PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3wla RCSB], [https://www.ebi.ac.uk/pdbsum/3wla PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3wla ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/OPH_SPHS1 OPH_SPHS1]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 23:		Line 23:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Beta-diketone hydrolase]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Sphs1~~]]	+	[[Category: Sphingopyxis sp. 113P3]]
-	[[Category: Chan~~, H C~~]]	+	[[Category: Chan HC]]
-	[[Category: Chen, J]]	+	[[Category: Chen J]]
-	[[Category: Du~~, G C~~]]	+	[[Category: Du GC]]
-	[[Category: Guo~~, R T~~]]	+	[[Category: Guo RT]]
-	[[Category: Huang~~, C H~~]]	+	[[Category: Huang CH]]
-	[[Category: Jia~~, D X~~]]	+	[[Category: Jia DX]]
-	[[Category: Ko~~, T P~~]]	+	[[Category: Ko TP]]
-	[[Category: Li~~, J H~~]]	+	[[Category: Li JH]]
-	[[Category: Liu, L]]	+	[[Category: Liu L]]
-	[[Category: Ren~~, F F~~]]	+	[[Category: Ren FF]]
-	[[Category: Wang~~, A H.~~J]]	+	[[Category: Wang AH-J]]
-	[[Category: Yang, Y]]	+	[[Category: Yang Y]]
-	~~[[Category: Alpha/beta-hydrolase]]~~	+
-	~~[[Category: Hydrolase]]~~	+
-	~~[[Category: Oxi-polyvinyl alcohol hydrolase~~]]	+

OCA at 05:41, 3 August 2022

OCA — Wed, 03 Aug 2022 05:41:03 GMT

←Older revision		Revision as of 05:41, 3 August 2022
Line 1:		Line 1:

	==Crystal Structure of sOPH Native==		==Crystal Structure of sOPH Native==
-	<StructureSection load='3wla' size='340' side='right' caption='[[3wla]], [[Resolution\|resolution]] 1.90Å' scene=''>	+	<StructureSection load='3wla' size='340' side='right'caption='[[3wla]], [[Resolution\|resolution]] 1.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3wla]] is a 3 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Sphs1 Sphs1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WLA OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3WLA FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3wla]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Sphs1 Sphs1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WLA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3WLA FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3wl5\|3wl5]], [[3wl6\|3wl6]], [[3wl7\|3wl7]], [[3wl8\|3wl8]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3wl5\|3wl5]], [[3wl6\|3wl6]], [[3wl7\|3wl7]], [[3wl8\|3wl8]]</div></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">oph ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=292913 SPHS1])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">oph ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=292913 SPHS1])</td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/Beta-diketone_hydrolase Beta-diketone hydrolase], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.7.1.7 3.7.1.7] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Beta-diketone_hydrolase Beta-diketone hydrolase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.7.1.7 3.7.1.7] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3wla FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wla OCA], [~~http~~://pdbe.org/3wla PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3wla RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3wla PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3wla ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3wla FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wla OCA], [https://pdbe.org/3wla PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3wla RCSB], [https://www.ebi.ac.uk/pdbsum/3wla PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3wla ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 24:		Line 24:
	</StructureSection>		</StructureSection>
	[[Category: Beta-diketone hydrolase]]		[[Category: Beta-diketone hydrolase]]
		+	[[Category: Large Structures]]
	[[Category: Sphs1]]		[[Category: Sphs1]]
	[[Category: Chan, H C]]		[[Category: Chan, H C]]

OCA at 08:07, 22 November 2017

OCA — Wed, 22 Nov 2017 08:07:37 GMT

←Older revision		Revision as of 08:07, 22 November 2017
Line 3:		Line 3:
	<StructureSection load='3wla' size='340' side='right' caption='[[3wla]], [[Resolution\|resolution]] 1.90Å' scene=''>		<StructureSection load='3wla' size='340' side='right' caption='[[3wla]], [[Resolution\|resolution]] 1.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3wla]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WLA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3WLA FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3wla]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Sphs1 Sphs1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WLA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3WLA FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3wl5\|3wl5]], [[3wl6\|3wl6]], [[3wl7\|3wl7]], [[3wl8\|3wl8]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3wl5\|3wl5]], [[3wl6\|3wl6]], [[3wl7\|3wl7]], [[3wl8\|3wl8]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">oph ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=292913 SPHS1])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-diketone_hydrolase Beta-diketone hydrolase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.7.1.7 3.7.1.7] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-diketone_hydrolase Beta-diketone hydrolase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.7.1.7 3.7.1.7] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3wla FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wla OCA], [http://pdbe.org/3wla PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3wla RCSB], [http://www.ebi.ac.uk/pdbsum/3wla PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3wla ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3wla FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wla OCA], [http://pdbe.org/3wla PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3wla RCSB], [http://www.ebi.ac.uk/pdbsum/3wla PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3wla ProSAT]</span></td></tr>
Line 23:		Line 24:
	</StructureSection>		</StructureSection>
	[[Category: Beta-diketone hydrolase]]		[[Category: Beta-diketone hydrolase]]
		+	[[Category: Sphs1]]
	[[Category: Chan, H C]]		[[Category: Chan, H C]]
	[[Category: Chen, J]]		[[Category: Chen, J]]

OCA at 14:33, 11 August 2016

OCA — Thu, 11 Aug 2016 14:33:46 GMT

←Older revision		Revision as of 14:33, 11 August 2016
Line 1:		Line 1:
		+
	==Crystal Structure of sOPH Native==		==Crystal Structure of sOPH Native==
	<StructureSection load='3wla' size='340' side='right' caption='[[3wla]], [[Resolution\|resolution]] 1.90Å' scene=''>		<StructureSection load='3wla' size='340' side='right' caption='[[3wla]], [[Resolution\|resolution]] 1.90Å' scene=''>
Line 6:		Line 7:
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3wl5\|3wl5]], [[3wl6\|3wl6]], [[3wl7\|3wl7]], [[3wl8\|3wl8]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3wl5\|3wl5]], [[3wl6\|3wl6]], [[3wl7\|3wl7]], [[3wl8\|3wl8]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-diketone_hydrolase Beta-diketone hydrolase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.7.1.7 3.7.1.7] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-diketone_hydrolase Beta-diketone hydrolase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.7.1.7 3.7.1.7] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3wla FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wla OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3wla RCSB], [http://www.ebi.ac.uk/pdbsum/3wla PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3wla FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wla OCA], [http://pdbe.org/3wla PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3wla RCSB], [http://www.ebi.ac.uk/pdbsum/3wla PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3wla ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 16:		Line 17:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3wla" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 08:09, 20 January 2015

OCA — Tue, 20 Jan 2015 08:09:39 GMT

←Older revision		Revision as of 08:09, 20 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3wla]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WLA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3WLA FirstGlance]. <br>		<table><tr><td colspan='2'>[[3wla]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WLA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3WLA FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3wl5\|3wl5]], [[3wl6\|3wl6]], [[3wl7\|3wl7]], [[3wl8\|3wl8]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3wl5\|3wl5]], [[3wl6\|3wl6]], [[3wl7\|3wl7]], [[3wl8\|3wl8]]</td></tr>
-	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-diketone_hydrolase Beta-diketone hydrolase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.7.1.7 3.7.1.7] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-diketone_hydrolase Beta-diketone hydrolase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.7.1.7 3.7.1.7] </span></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3wla FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wla OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3wla RCSB], [http://www.ebi.ac.uk/pdbsum/3wla PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3wla FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wla OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3wla RCSB], [http://www.ebi.ac.uk/pdbsum/3wla PDBsum]</span></td></tr>
-	<table>	+	</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 21:		Line 21:
	</StructureSection>		</StructureSection>
	[[Category: Beta-diketone hydrolase]]		[[Category: Beta-diketone hydrolase]]
-	[[Category: Chan, H C.]]	+	[[Category: Chan, H C]]
-	[[Category: Chen, J.]]	+	[[Category: Chen, J]]
-	[[Category: Du, G C.]]	+	[[Category: Du, G C]]
-	[[Category: Guo, R T.]]	+	[[Category: Guo, R T]]
-	[[Category: Huang, C H.]]	+	[[Category: Huang, C H]]
-	[[Category: Jia, D X.]]	+	[[Category: Jia, D X]]
-	[[Category: Ko, T P.]]	+	[[Category: Ko, T P]]
-	[[Category: Li, J H.]]	+	[[Category: Li, J H]]
-	[[Category: Liu, L.]]	+	[[Category: Liu, L]]
-	[[Category: Ren, F F.]]	+	[[Category: Ren, F F]]
-	[[Category: Wang, A H.J.]]	+	[[Category: Wang, A H.J]]
-	[[Category: Yang, Y.]]	+	[[Category: Yang, Y]]
	[[Category: Alpha/beta-hydrolase]]		[[Category: Alpha/beta-hydrolase]]
	[[Category: Hydrolase]]		[[Category: Hydrolase]]
	[[Category: Oxi-polyvinyl alcohol hydrolase]]		[[Category: Oxi-polyvinyl alcohol hydrolase]]

OCA at 10:36, 24 September 2014

OCA — Wed, 24 Sep 2014 10:36:58 GMT

←Older revision		Revision as of 10:36, 24 September 2014
Line 1:		Line 1:
-	'''~~Unreleased~~ structure'''	+	==Crystal Structure of sOPH Native==
		+	<StructureSection load='3wla' size='340' side='right' caption='[[3wla]], [[Resolution\|resolution]] 1.90Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[3wla]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WLA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3WLA FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3wl5\|3wl5]], [[3wl6\|3wl6]], [[3wl7\|3wl7]], [[3wl8\|3wl8]]</td></tr>
		+	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-diketone_hydrolase Beta-diketone hydrolase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.7.1.7 3.7.1.7] </span></td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3wla FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wla OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3wla RCSB], [http://www.ebi.ac.uk/pdbsum/3wla PDBsum]</span></td></tr>
		+	<table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The ever-increasing production and use of polyvinyl alcohol (PVA) threaten our environment. Yet PVA can be assimilated by microbes in two steps: oxidation and cleavage. Here we report novel alpha/beta-hydrolase structures of oxidized PVA hydrolase (OPH) from two known PVA-degrading organisms, Sphingopyxis sp. 113P3 and Pseudomonas sp. VM15C, including complexes with substrate analogues, acetylacetone and caprylate. The active site is covered by a lid-like beta-ribbon. Unlike other esterase and amidase, OPH is unique in cleaving the CC bond of beta-diketone, although it has a catalytic triad similar to that of most alpha/beta-hydrolases. Analysis of the crystal structures suggests a double-oxyanion-hole mechanism, previously only found in thiolase cleaving beta-ketoacyl-CoA. Three mutations in the lid region showed enhanced activity, with potential in industrial applications.

-	~~The entry 3wla is ON HOLD until Paper Publication~~	+	Structural insights into enzymatic degradation of oxidized polyvinyl alcohol.,Yang Y, Ko TP, Liu L, Li J, Huang CH, Chan HC, Ren F, Jia D, Wang AH, Guo RT, Chen J, Du G Chembiochem. 2014 Sep 5;15(13):1882-6. doi: 10.1002/cbic.201402166. Epub 2014 Jul, 8. PMID:25044912<ref>PMID:25044912</ref>

-	~~Authors: Yang~~, Y.~~, Ko, T~~.P., ~~Li, J.~~H., ~~Liu~~, L., Huang, C.H., ~~Chan~~, H.C., Ren, F.F.~~, Jia, D.X.,~~ Wang, A.H.-J., ~~Guo, R.T., Chen, J., Du, G.C~~.	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~Description~~: ~~Crystal Structure of sOPH Native~~	+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Beta-diketone hydrolase]]
		+	[[Category: Chan, H C.]]
		+	[[Category: Chen, J.]]
		+	[[Category: Du, G C.]]
		+	[[Category: Guo, R T.]]
		+	[[Category: Huang, C H.]]
		+	[[Category: Jia, D X.]]
		+	[[Category: Ko, T P.]]
		+	[[Category: Li, J H.]]
		+	[[Category: Liu, L.]]
		+	[[Category: Ren, F F.]]
		+	[[Category: Wang, A H.J.]]
		+	[[Category: Yang, Y.]]
		+	[[Category: Alpha/beta-hydrolase]]
		+	[[Category: Hydrolase]]
		+	[[Category: Oxi-polyvinyl alcohol hydrolase]]

OCA at 08:43, 18 December 2013

OCA — Wed, 18 Dec 2013 08:43:20 GMT

←Older revision		Revision as of 08:43, 18 December 2013
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 3wla is ON HOLD	+	The entry 3wla is ON HOLD until Paper Publication

	Authors: Yang, Y., Ko, T.P., Li, J.H., Liu, L., Huang, C.H., Chan, H.C., Ren, F.F., Jia, D.X., Wang, A.H.-J., Guo, R.T., Chen, J., Du, G.C.		Authors: Yang, Y., Ko, T.P., Li, J.H., Liu, L., Huang, C.H., Chan, H.C., Ren, F.F., Jia, D.X., Wang, A.H.-J., Guo, R.T., Chen, J., Du, G.C.

	Description: Crystal Structure of sOPH Native		Description: Crystal Structure of sOPH Native

OCA at 06:27, 4 December 2013

OCA — Wed, 04 Dec 2013 06:27:10 GMT

←Older revision		Revision as of 06:27, 4 December 2013
Line 3:		Line 3:
	The entry 3wla is ON HOLD		The entry 3wla is ON HOLD

-	Authors: Yang, Y. , Ko, T.P., Li, J.H., Liu, L., Huang, C.H., Chan, H.C., Ren, F.F., Jia, D.X., Wang, A. H.J., Guo, R.T., Chen, J., Du, G.C.	+	Authors: Yang, Y., Ko, T.P., Li, J.H., Liu, L., Huang, C.H., Chan, H.C., Ren, F.F., Jia, D.X., Wang, A.H.-J., Guo, R.T., Chen, J., Du, G.C.

	Description: Crystal Structure of sOPH Native		Description: Crystal Structure of sOPH Native

OCA: Protected "3wla" [edit=sysop:move=sysop]

OCA — Wed, 13 Nov 2013 07:07:47 GMT

Protected "3wla" [edit=sysop:move=sysop]

←Older revision

Revision as of 07:07, 13 November 2013

OCA: New page: '''Unreleased structure''' The entry 3wla is ON HOLD Authors: Yang, Y. , Ko, T.P., Li, J.H., Liu, L., Huang, C.H., Chan, H.C., Ren, F.F., Jia, D.X., Wang, A. H.J., Guo, R.T., Chen, J., ...

OCA — Wed, 13 Nov 2013 07:07:46 GMT

New page: '''Unreleased structure''' The entry 3wla is ON HOLD Authors: Yang, Y. , Ko, T.P., Li, J.H., Liu, L., Huang, C.H., Chan, H.C., Ren, F.F., Jia, D.X., Wang, A. H.J., Guo, R.T., Chen, J., ...

New page

'''Unreleased structure'''

The entry 3wla is ON HOLD

Authors: Yang, Y. , Ko, T.P., Li, J.H., Liu, L., Huang, C.H., Chan, H.C., Ren, F.F., Jia, D.X., Wang, A. H.J., Guo, R.T., Chen, J., Du, G.C.

Description: Crystal Structure of sOPH Native