3wo7 - Revision history

OCA at 08:46, 20 March 2024

OCA — Wed, 20 Mar 2024 08:46:12 GMT

←Older revision		Revision as of 08:46, 20 March 2024
Line 3:		Line 3:
	<StructureSection load='3wo7' size='340' side='right'caption='[[3wo7]], [[Resolution\|resolution]] 3.20Å' scene=''>		<StructureSection load='3wo7' size='340' side='right'caption='[[3wo7]], [[Resolution\|resolution]] 3.20Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3wo7]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Bachd Bachd~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WO7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3WO7 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3wo7]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Alkalihalobacillus_halodurans_C-125 Alkalihalobacillus halodurans C-125]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WO7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3WO7 FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 3.201Å</td></tr>
-	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"~~><div style~~=~~'overflow: auto; max-height: 3em;'~~>~~[[3w06\|3w06]]~~<~~/div></td></tr>~~	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene></td></tr>
-	~~<tr id~~='~~gene'><td class~~=~~"sblockLbl"><b>[[Gene\|Gene~~:~~]]</b~~></td>~~<td class="sblockDat">yidC2, BH1169 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=272558 BACHD])~~</td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3wo7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wo7 OCA], [https://pdbe.org/3wo7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3wo7 RCSB], [https://www.ebi.ac.uk/pdbsum/3wo7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3wo7 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3wo7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wo7 OCA], [https://pdbe.org/3wo7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3wo7 RCSB], [https://www.ebi.ac.uk/pdbsum/3wo7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3wo7 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/~~YIDC2_BACHD YIDC2_BACHD]~~] Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins ~~(By similarity)~~.	+	[https://www.uniprot.org/uniprot/YIDC2_HALH5 YIDC2_HALH5] Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.[HAMAP-Rule:MF_01811]
-	~~<div style="background~~-~~color~~:~~#fffaf0;">~~	+
-	~~== Publication Abstract from PubMed ==~~	+
-	Newly synthesized membrane proteins must be accurately inserted into the membrane, folded and assembled for proper functioning. The protein YidC inserts its substrates into the membrane, thereby facilitating membrane protein assembly in bacteria; the homologous proteins Oxa1 and Alb3 have the same function in mitochondria and chloroplasts, respectively. In the bacterial cytoplasmic membrane, YidC functions as an independent insertase and a membrane chaperone in cooperation with the translocon SecYEG. Here we present the crystal structure of YidC from Bacillus halodurans, at 2.4 A resolution. The structure reveals a novel fold, in which five conserved transmembrane helices form a positively charged hydrophilic groove that is open towards both the lipid bilayer and the cytoplasm but closed on the extracellular side. Structure-based in vivo analyses reveal that a conserved arginine residue in the groove is important for the insertion of membrane proteins by YidC. We propose an insertion mechanism for single-spanning membrane proteins, in which the hydrophilic environment generated by the groove recruits the extracellular regions of substrates into the low-dielectric environment of the membrane.	+
-		+
-	Structural basis of Sec-independent membrane protein insertion by YidC.,Kumazaki K, Chiba S, Takemoto M, Furukawa A, Nishiyama K, Sugano Y, Mori T, Dohmae N, Hirata K, Nakada-Nakura Y, Maturana AD, Tanaka Y, Mori H, Sugita Y, Arisaka F, Ito K, Ishitani R, Tsukazaki T, Nureki O Nature. 2014 May 22;509(7501):516-20. doi: 10.1038/nature13167. Epub 2014 Apr 16. PMID:24739968<ref>PMID:24739968</ref>	+
-		+
-	~~From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>~~	+
-	~~</div>~~	+
-	~~<div class="pdbe-citations 3wo7" style="background-color:#fffaf0;"></div>~~	+

	==See Also==		==See Also==
	*[[Insertase\|Insertase]]		*[[Insertase\|Insertase]]
-	== References ==
-	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Bachd~~]]	+	[[Category: Alkalihalobacillus halodurans C-125]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Ishitani, R]]	+	[[Category: Ishitani R]]
-	[[Category: Kumazaki, K]]	+	[[Category: Kumazaki K]]
-	[[Category: Nureki, O]]	+	[[Category: Nureki O]]
-	[[Category: Tsukazaki, T]]	+	[[Category: Tsukazaki T]]
-	~~[[Category: Alpha helical]]~~	+
-	~~[[Category: Membrane protein~~]]	+

OCA at 05:43, 3 August 2022

OCA — Wed, 03 Aug 2022 05:43:53 GMT

←Older revision		Revision as of 05:43, 3 August 2022
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	<StructureSection load='3wo7' size='340' side='right'caption='[[3wo7]], [[Resolution\|resolution]] 3.20Å' scene=''>		<StructureSection load='3wo7' size='340' side='right'caption='[[3wo7]], [[Resolution\|resolution]] 3.20Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3wo7]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Bachd Bachd]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WO7 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3WO7 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3wo7]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bachd Bachd]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WO7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3WO7 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3w06\|3w06]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3w06\|3w06]]</div></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">yidC2, BH1169 ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=272558 BACHD])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">yidC2, BH1169 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=272558 BACHD])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3wo7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wo7 OCA], [~~http~~://pdbe.org/3wo7 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3wo7 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3wo7 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3wo7 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3wo7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wo7 OCA], [https://pdbe.org/3wo7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3wo7 RCSB], [https://www.ebi.ac.uk/pdbsum/3wo7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3wo7 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/YIDC2_BACHD YIDC2_BACHD]] Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins (By similarity).	+	[[https://www.uniprot.org/uniprot/YIDC2_BACHD YIDC2_BACHD]] Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins (By similarity).
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==

OCA at 08:16, 18 December 2019

OCA — Wed, 18 Dec 2019 08:16:57 GMT

←Older revision		Revision as of 08:16, 18 December 2019
Line 1:		Line 1:

	==Crystal structure of YidC from Bacillus halodurans (form II)==		==Crystal structure of YidC from Bacillus halodurans (form II)==
-	<StructureSection load='3wo7' size='340' side='right' caption='[[3wo7]], [[Resolution\|resolution]] 3.20Å' scene=''>	+	<StructureSection load='3wo7' size='340' side='right'caption='[[3wo7]], [[Resolution\|resolution]] 3.20Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3wo7]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bachd Bachd]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WO7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3WO7 FirstGlance]. <br>		<table><tr><td colspan='2'>[[3wo7]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bachd Bachd]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WO7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3WO7 FirstGlance]. <br>
Line 11:		Line 11:
	== Function ==		== Function ==
	[[http://www.uniprot.org/uniprot/YIDC2_BACHD YIDC2_BACHD]] Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins (By similarity).		[[http://www.uniprot.org/uniprot/YIDC2_BACHD YIDC2_BACHD]] Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins (By similarity).
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Newly synthesized membrane proteins must be accurately inserted into the membrane, folded and assembled for proper functioning. The protein YidC inserts its substrates into the membrane, thereby facilitating membrane protein assembly in bacteria; the homologous proteins Oxa1 and Alb3 have the same function in mitochondria and chloroplasts, respectively. In the bacterial cytoplasmic membrane, YidC functions as an independent insertase and a membrane chaperone in cooperation with the translocon SecYEG. Here we present the crystal structure of YidC from Bacillus halodurans, at 2.4 A resolution. The structure reveals a novel fold, in which five conserved transmembrane helices form a positively charged hydrophilic groove that is open towards both the lipid bilayer and the cytoplasm but closed on the extracellular side. Structure-based in vivo analyses reveal that a conserved arginine residue in the groove is important for the insertion of membrane proteins by YidC. We propose an insertion mechanism for single-spanning membrane proteins, in which the hydrophilic environment generated by the groove recruits the extracellular regions of substrates into the low-dielectric environment of the membrane.
		+
		+	Structural basis of Sec-independent membrane protein insertion by YidC.,Kumazaki K, Chiba S, Takemoto M, Furukawa A, Nishiyama K, Sugano Y, Mori T, Dohmae N, Hirata K, Nakada-Nakura Y, Maturana AD, Tanaka Y, Mori H, Sugita Y, Arisaka F, Ito K, Ishitani R, Tsukazaki T, Nureki O Nature. 2014 May 22;509(7501):516-20. doi: 10.1038/nature13167. Epub 2014 Apr 16. PMID:24739968<ref>PMID:24739968</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	<div class="pdbe-citations 3wo7" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Insertase\|Insertase]]
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: Bachd]]		[[Category: Bachd]]
		+	[[Category: Large Structures]]
	[[Category: Ishitani, R]]		[[Category: Ishitani, R]]
	[[Category: Kumazaki, K]]		[[Category: Kumazaki, K]]

OCA at 14:02, 4 August 2016

OCA — Thu, 04 Aug 2016 14:02:41 GMT

←Older revision		Revision as of 14:02, 4 August 2016
Line 1:		Line 1:
		+
	==Crystal structure of YidC from Bacillus halodurans (form II)==		==Crystal structure of YidC from Bacillus halodurans (form II)==
	<StructureSection load='3wo7' size='340' side='right' caption='[[3wo7]], [[Resolution\|resolution]] 3.20Å' scene=''>		<StructureSection load='3wo7' size='340' side='right' caption='[[3wo7]], [[Resolution\|resolution]] 3.20Å' scene=''>
Line 6:		Line 7:
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3w06\|3w06]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3w06\|3w06]]</td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">yidC2, BH1169 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=272558 BACHD])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">yidC2, BH1169 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=272558 BACHD])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3wo7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wo7 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3wo7 RCSB], [http://www.ebi.ac.uk/pdbsum/3wo7 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3wo7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wo7 OCA], [http://pdbe.org/3wo7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3wo7 RCSB], [http://www.ebi.ac.uk/pdbsum/3wo7 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3wo7 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==

OCA at 09:58, 25 December 2014

OCA — Thu, 25 Dec 2014 09:58:11 GMT

←Older revision		Revision as of 09:58, 25 December 2014
Line 2:		Line 2:
	<StructureSection load='3wo7' size='340' side='right' caption='[[3wo7]], [[Resolution\|resolution]] 3.20Å' scene=''>		<StructureSection load='3wo7' size='340' side='right' caption='[[3wo7]], [[Resolution\|resolution]] 3.20Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3wo7]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WO7 OCA]. <br>	+	<table><tr><td colspan='2'>[[3wo7]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bachd Bachd]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WO7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3WO7 FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3w06\|3w06]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3w06\|3w06]]</td></tr>
-	<tr><td class="sblockLbl"><b>~~Activity~~:</b></td><td class="sblockDat">~~<span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase]~~, ~~with EC number~~ [http://www.~~brenda-enzymes~~.~~info~~/~~php~~/~~result_flat~~.~~php4~~?~~ecno~~=~~2.7.1.2 2.7.1.2~~] ~~</span>~~</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">yidC2, BH1169 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=272558 BACHD])</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3wo7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wo7 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3wo7 RCSB], [http://www.ebi.ac.uk/pdbsum/3wo7 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3wo7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wo7 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3wo7 RCSB], [http://www.ebi.ac.uk/pdbsum/3wo7 PDBsum]</span></td></tr>
-	<table>	+	</table>
-	== ~~References~~ ==	+	== Function ==
-	~~<references~~/>	+	[[http://www.uniprot.org/uniprot/YIDC2_BACHD YIDC2_BACHD]] Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins (By similarity).
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Ishitani, R.]]	+	[[Category: Bachd]]
-	[[Category: Kumazaki, K.]]	+	[[Category: Ishitani, R]]
-	[[Category: Nureki, O.]]	+	[[Category: Kumazaki, K]]
-	[[Category: Tsukazaki, T.]]	+	[[Category: Nureki, O]]
		+	[[Category: Tsukazaki, T]]
	[[Category: Alpha helical]]		[[Category: Alpha helical]]
	[[Category: Membrane protein]]		[[Category: Membrane protein]]

OCA at 09:37, 1 May 2014

OCA — Thu, 01 May 2014 09:37:36 GMT

←Older revision		Revision as of 09:37, 1 May 2014
Line 2:		Line 2:
	<StructureSection load='3wo7' size='340' side='right' caption='[[3wo7]], [[Resolution\|resolution]] 3.20Å' scene=''>		<StructureSection load='3wo7' size='340' side='right' caption='[[3wo7]], [[Resolution\|resolution]] 3.20Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	[[3wo7]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WO7 OCA]. <br>	+	<table><tr><td colspan='2'>[[3wo7]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WO7 OCA]. <br>
-	<b>[[Ligand\|Ligands:]]</b> <scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene><br>	+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene><br>
-	<b>[[Related_structure\|Related:]]</b> [[3w06\|3w06]]<br>	+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3w06\|3w06]]</td></tr>
-	<b>Activity:</b> <span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span><br>	+	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span></td></tr>
-	<b>Resources:</b> <span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3wo7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wo7 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3wo7 RCSB], [http://www.ebi.ac.uk/pdbsum/3wo7 PDBsum]</span><br>	+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3wo7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wo7 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3wo7 RCSB], [http://www.ebi.ac.uk/pdbsum/3wo7 PDBsum]</span></td></tr>
		+	<table>
	== References ==		== References ==
	<references/>		<references/>

OCA at 10:11, 30 April 2014

OCA — Wed, 30 Apr 2014 10:11:41 GMT

←Older revision		Revision as of 10:11, 30 April 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	[[3wo7]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WO7 OCA]. <br>		[[3wo7]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WO7 OCA]. <br>
-	<b>Related:</b> [[3w06\|3w06]]<br>	+	<b>[[Ligand\|Ligands:]]</b> <scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene><br>
		+	<b>[[Related_structure\|Related:]]</b> [[3w06\|3w06]]<br>
	<b>Activity:</b> <span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span><br>		<b>Activity:</b> <span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span><br>
		+	<b>Resources:</b> <span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3wo7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wo7 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3wo7 RCSB], [http://www.ebi.ac.uk/pdbsum/3wo7 PDBsum]</span><br>
	== References ==		== References ==
	<references/>		<references/>

OCA at 05:32, 30 April 2014

OCA — Wed, 30 Apr 2014 05:32:00 GMT

←Older revision		Revision as of 05:32, 30 April 2014
Line 1:		Line 1:
-	~~{{STRUCTURE_3wo7\| PDB=3wo7 \| SCENE= }}~~	+	==Crystal structure of YidC from Bacillus halodurans (form II)==
-	===Crystal structure of ~~protein=~~==	+	<StructureSection load='3wo7' size='340' side='right' caption='[[3wo7]], [[Resolution\|resolution]] 3.20Å' scene=''>
-		+	== Structural highlights ==
-	==~~Function~~==	+	[[3wo7]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WO7 OCA]. <br>
-	[[~~http://www.uniprot.org/uniprot/YIDC2_BACHD YIDC2_BACHD~~]] Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, ~~as well as at least some lipoproteins (By similarity)~~.	+	<b>Related:</b> [[3w06\|3w06]]<br>
-		+	<b>Activity:</b> <span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span><br>
-	==~~About this Structure~~==	+	== References ==
-	[[3wo7]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WO7 OCA].	+	<references/>
		+	__TOC__
		+	</StructureSection>
	[[Category: Ishitani, R.]]		[[Category: Ishitani, R.]]
	[[Category: Kumazaki, K.]]		[[Category: Kumazaki, K.]]

OCA at 07:49, 23 April 2014

OCA — Wed, 23 Apr 2014 07:49:35 GMT

←Older revision		Revision as of 07:49, 23 April 2014
Line 1:		Line 1:
-	~~'''Unreleased~~ structure~~'''~~	+	{{STRUCTURE_3wo7\| PDB=3wo7 \| SCENE= }}
		+	===Crystal structure of protein===

-	~~The entry 3wo7 is ON HOLD until Paper Publication~~	+	==Function==
		+	[[http://www.uniprot.org/uniprot/YIDC2_BACHD YIDC2_BACHD]] Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins (By similarity).

-	~~Authors~~: ~~Kumazaki, K~~.~~, Tsukazaki, T~~., Ishitani, R., Nureki, O.	+	==About this Structure==
-		+	[[3wo7]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WO7 OCA].
-	~~Description~~: ~~Crystal structure of~~ protein	+	[[Category: Ishitani, R.]]
		+	[[Category: Kumazaki, K.]]
		+	[[Category: Nureki, O.]]
		+	[[Category: Tsukazaki, T.]]
		+	[[Category: Alpha helical]]
		+	[[Category: Membrane protein]]

OCA at 08:41, 8 January 2014

OCA — Wed, 08 Jan 2014 08:41:05 GMT

←Older revision		Revision as of 08:41, 8 January 2014
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 3wo7 is ON HOLD	+	The entry 3wo7 is ON HOLD until Paper Publication

	Authors: Kumazaki, K., Tsukazaki, T., Ishitani, R., Nureki, O.		Authors: Kumazaki, K., Tsukazaki, T., Ishitani, R., Nureki, O.

	Description: Crystal structure of protein		Description: Crystal structure of protein