3wzt - Revision history

OCA at 13:35, 8 November 2023

OCA — Wed, 08 Nov 2023 13:35:46 GMT

←Older revision		Revision as of 13:35, 8 November 2023
Line 3:		Line 3:
	<StructureSection load='3wzt' size='340' side='right'caption='[[3wzt]], [[Resolution\|resolution]] 3.40Å' scene=''>		<StructureSection load='3wzt' size='340' side='right'caption='[[3wzt]], [[Resolution\|resolution]] 3.40Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3wzt]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Chatd Chatd~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WZT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3WZT FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3wzt]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Chaetomium_thermophilum_var._thermophilum_DSM_1495 Chaetomium thermophilum var. thermophilum DSM 1495]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WZT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3WZT FirstGlance]. <br>
-	</td></tr><tr id='~~NonStdRes~~'><td class="sblockLbl"><b>[[~~Non-Standard_Residue~~\|~~NonStd Res~~:]]</b></td><td class="sblockDat"~~><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 3.4Å</td></tr>
-	~~<tr~~ id~~='related'><td class~~="~~sblockLbl~~">~~<b>~~[[~~Related_structure~~\|~~Related:~~]]~~</b></td><td class="sblockDat"><div style='overflow: auto~~; ~~max-height: 3em;'>[[3wzs\|3wzs]]</div>~~</td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
-	<tr id='~~gene~~'><td class="sblockLbl"><b>[[~~Gene~~\|~~Gene~~:]]</b></td><td class="sblockDat">~~CTHT_0048990 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode~~=~~Info&srchmode~~=~~5&id=759272 CHATD])~~</td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3wzt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wzt OCA], [https://pdbe.org/3wzt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3wzt RCSB], [https://www.ebi.ac.uk/pdbsum/3wzt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3wzt ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3wzt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wzt OCA], [https://pdbe.org/3wzt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3wzt RCSB], [https://www.ebi.ac.uk/pdbsum/3wzt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3wzt ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/G0SB58_CHATD G0SB58_CHATD]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 22:		Line 23:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Chatd~~]]	+	[[Category: Chaetomium thermophilum var. thermophilum DSM 1495]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Kato, K]]	+	[[Category: Kato K]]
-	[[Category: Satoh, T]]	+	[[Category: Satoh T]]
-	[[Category: Zhu, T]]	+	[[Category: Zhu T]]
-	~~[[Category: Endoplasmic reticulum]]~~	+
-	~~[[Category: Folding sensor]]~~	+
-	~~[[Category: Glucosyltransferase]]~~	+
-	~~[[Category: Quality control]]~~	+
-	~~[[Category: Thioredoxin fold]]~~	+
-	~~[[Category: Thioredoxin-like]]~~	+
-	~~[[Category: Transferase~~]]	+

OCA at 05:36, 10 August 2022

OCA — Wed, 10 Aug 2022 05:36:49 GMT

←Older revision		Revision as of 05:36, 10 August 2022
Line 1:		Line 1:

	==Crystal structure of Trx3 domain of UGGT (detergent-unbound form)==		==Crystal structure of Trx3 domain of UGGT (detergent-unbound form)==
-	<StructureSection load='3wzt' size='340' side='right' caption='[[3wzt]], [[Resolution\|resolution]] 3.40Å' scene=''>	+	<StructureSection load='3wzt' size='340' side='right'caption='[[3wzt]], [[Resolution\|resolution]] 3.40Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3wzt]] is a 6 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Chatd Chatd]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WZT OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3WZT FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3wzt]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Chatd Chatd]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WZT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3WZT FirstGlance]. <br>
	</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>		</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3wzs\|3wzs]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3wzs\|3wzs]]</div></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">CTHT_0048990 ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=759272 CHATD])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">CTHT_0048990 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=759272 CHATD])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3wzt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wzt OCA], [~~http~~://pdbe.org/3wzt PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3wzt RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3wzt PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3wzt ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3wzt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wzt OCA], [https://pdbe.org/3wzt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3wzt RCSB], [https://www.ebi.ac.uk/pdbsum/3wzt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3wzt ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 23:		Line 23:
	</StructureSection>		</StructureSection>
	[[Category: Chatd]]		[[Category: Chatd]]
		+	[[Category: Large Structures]]
	[[Category: Kato, K]]		[[Category: Kato, K]]
	[[Category: Satoh, T]]		[[Category: Satoh, T]]

OCA at 17:02, 27 February 2019

OCA — Wed, 27 Feb 2019 17:02:39 GMT

←Older revision		Revision as of 17:02, 27 February 2019
Line 3:		Line 3:
	<StructureSection load='3wzt' size='340' side='right' caption='[[3wzt]], [[Resolution\|resolution]] 3.40Å' scene=''>		<StructureSection load='3wzt' size='340' side='right' caption='[[3wzt]], [[Resolution\|resolution]] 3.40Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3wzt]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WZT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3WZT FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3wzt]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Chatd Chatd]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WZT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3WZT FirstGlance]. <br>
	</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>		</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3wzs\|3wzs]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3wzs\|3wzs]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">CTHT_0048990 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=759272 CHATD])</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3wzt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wzt OCA], [http://pdbe.org/3wzt PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3wzt RCSB], [http://www.ebi.ac.uk/pdbsum/3wzt PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3wzt ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3wzt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wzt OCA], [http://pdbe.org/3wzt PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3wzt RCSB], [http://www.ebi.ac.uk/pdbsum/3wzt PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3wzt ProSAT]</span></td></tr>
	</table>		</table>
Line 21:		Line 22:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Chatd]]
	[[Category: Kato, K]]		[[Category: Kato, K]]
	[[Category: Satoh, T]]		[[Category: Satoh, T]]

OCA at 20:45, 5 August 2016

OCA — Fri, 05 Aug 2016 20:45:50 GMT

←Older revision		Revision as of 20:45, 5 August 2016
Line 1:		Line 1:
		+
	==Crystal structure of Trx3 domain of UGGT (detergent-unbound form)==		==Crystal structure of Trx3 domain of UGGT (detergent-unbound form)==
	<StructureSection load='3wzt' size='340' side='right' caption='[[3wzt]], [[Resolution\|resolution]] 3.40Å' scene=''>		<StructureSection load='3wzt' size='340' side='right' caption='[[3wzt]], [[Resolution\|resolution]] 3.40Å' scene=''>
Line 5:		Line 6:
	</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>		</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3wzs\|3wzs]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3wzs\|3wzs]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3wzt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wzt OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3wzt RCSB], [http://www.ebi.ac.uk/pdbsum/3wzt PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3wzt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wzt OCA], [http://pdbe.org/3wzt PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3wzt RCSB], [http://www.ebi.ac.uk/pdbsum/3wzt PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3wzt ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 15:		Line 16:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3wzt" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 09:26, 31 December 2014

OCA — Wed, 31 Dec 2014 09:26:56 GMT

←Older revision		Revision as of 09:26, 31 December 2014
Line 7:		Line 7:
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3wzt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wzt OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3wzt RCSB], [http://www.ebi.ac.uk/pdbsum/3wzt PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3wzt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wzt OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3wzt RCSB], [http://www.ebi.ac.uk/pdbsum/3wzt PDBsum]</span></td></tr>
	</table>		</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The endoplasmic reticulum (ER) possesses a protein quality control system that supports the efficient folding of newly synthesized glycoproteins. In this system, a series of N-linked glycan intermediates displayed on proteins serve as quality tags. The ER folding-sensor enzyme UDP-glucose:glycoprotein glucosyltransferase (UGGT) operates as the gatekeeper for ER quality control by specifically transferring monoglucose residues to incompletely folded glycoproteins, thereby allowing them to interact with lectin chaperone complexes to facilitate their folding. Despite its functional importance, no structural information is available for this key enzyme to date. To elucidate the folding-sensor mechanism in the ER, we performed a structural study of UGGT. Based on bioinformatics analyses, the folding-sensor region of UGGT was predicted to harbour three tandem thioredoxin (Trx)-like domains, which are often found in proteins involved in ER quality control. Furthermore, we determined the three-dimensional structure of the third Trx-like domain, which exhibits an extensive hydrophobic patch concealed by its flexible C-terminal helix. Our structural data suggest that this hydrophobic patch is involved in intermolecular interactions, thereby contributing to the folding-sensor mechanism of UGGT.
		+
		+	Structural insight into substrate recognition by the endoplasmic reticulum folding-sensor enzyme: crystal structure of third thioredoxin-like domain of UDP-glucose:glycoprotein glucosyltransferase.,Zhu T, Satoh T, Kato K Sci Rep. 2014 Dec 4;4:7322. doi: 10.1038/srep07322. PMID:25471383<ref>PMID:25471383</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>

OCA at 09:38, 3 December 2014

OCA — Wed, 03 Dec 2014 09:38:15 GMT

←Older revision		Revision as of 09:38, 3 December 2014
Line 1:		Line 1:
-	'''~~Unreleased structure~~'''	+	==Crystal structure of Trx3 domain of UGGT (detergent-unbound form)==
-		+	<StructureSection load='3wzt' size='340' side='right' caption='[[3wzt]], [[Resolution\|resolution]] 3.40Å' scene=''>
-	~~The entry~~ 3wzt is ~~ON HOLD until Paper Publication~~	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[3wzt]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WZT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3WZT FirstGlance]. <br>
-	~~Authors~~: ~~Zhu~~, T., ~~Satoh, T~~., Kato, K.	+	</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
-		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3wzs\|3wzs]]</td></tr>
-	~~Description~~: ~~Crystal structure of fungal protein (cubic crystal form)~~	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3wzt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wzt OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3wzt RCSB], [http://www.ebi.ac.uk/pdbsum/3wzt PDBsum]</span></td></tr>
		+	</table>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Kato, K]]
		+	[[Category: Satoh, T]]
		+	[[Category: Zhu, T]]
		+	[[Category: Endoplasmic reticulum]]
		+	[[Category: Folding sensor]]
		+	[[Category: Glucosyltransferase]]
		+	[[Category: Quality control]]
		+	[[Category: Thioredoxin fold]]
		+	[[Category: Thioredoxin-like]]
		+	[[Category: Transferase]]

OCA: Protected "3wzt" [edit=sysop:move=sysop]

OCA — Mon, 20 Oct 2014 09:03:04 GMT

Protected "3wzt" [edit=sysop:move=sysop]

←Older revision

Revision as of 09:03, 20 October 2014

OCA: New page: '''Unreleased structure''' The entry 3wzt is ON HOLD until Paper Publication Authors: Zhu, T., Satoh, T., Kato, K. Description: Crystal structure of fungal protein (cubic crystal form)

OCA — Mon, 20 Oct 2014 09:03:03 GMT

New page: '''Unreleased structure''' The entry 3wzt is ON HOLD until Paper Publication Authors: Zhu, T., Satoh, T., Kato, K. Description: Crystal structure of fungal protein (cubic crystal form)

New page

'''Unreleased structure'''

The entry 3wzt is ON HOLD until Paper Publication

Authors: Zhu, T., Satoh, T., Kato, K.

Description: Crystal structure of fungal protein (cubic crystal form)