3zfn - Revision history

OCA at 07:12, 1 May 2024

OCA — Wed, 01 May 2024 07:12:50 GMT

←Older revision		Revision as of 07:12, 1 May 2024
Line 3:		Line 3:
	<StructureSection load='3zfn' size='340' side='right'caption='[[3zfn]], [[Resolution\|resolution]] 1.50Å' scene=''>		<StructureSection load='3zfn' size='340' side='right'caption='[[3zfn]], [[Resolution\|resolution]] 1.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3zfn]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Pestivirus_strain_d32~~/~~00_hobi~~ Pestivirus strain ~~d32~~/~~00_hobi~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZFN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3ZFN FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3zfn]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pestivirus_strain_D32/00_HoBi Pestivirus strain D32/00_HoBi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZFN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3ZFN FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>~~, ~~<scene name='pdbligand=SGM:MONOTHIOGLYCEROL'>SGM</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.5Å</td></tr>
-	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"><~~div style~~='~~overflow~~: ~~auto; max-height: 3em;~~'>~~[[3zfo\|3zfo]]~~, ~~[[3zfp\|3zfp]], [[3zfq\|3zfq]], [[3zfr\|3zfr]], [[3zft\|3zft]], [[3zfu\|3zfu]]~~</~~div~~></td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=SGM:MONOTHIOGLYCEROL'>SGM</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3zfn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zfn OCA], [https://pdbe.org/3zfn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3zfn RCSB], [https://www.ebi.ac.uk/pdbsum/3zfn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3zfn ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3zfn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zfn OCA], [https://pdbe.org/3zfn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3zfn RCSB], [https://www.ebi.ac.uk/pdbsum/3zfn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3zfn ProSAT]</span></td></tr>
	</table>		</table>
-	~~<div style~~=~~"background-color:#fffaf0;">~~	+	== Function ==
-	=~~= Publication Abstract from PubMed~~ ==	+	[https://www.uniprot.org/uniprot/Q5L4B1_9FLAV Q5L4B1_9FLAV]
-	Npro is a key effector protein of pestiviruses such as bovine viral diarrhea virus and abolishes host cell antiviral defense mechanisms. Synthesized as the N-terminal part of the viral polyprotein, Npro releases itself via an autoproteolytic cleavage, triggering its immunological functions. However, the mechanisms of its proteolytic action and its immune escape were unclear. Here, we present the crystal structures of Npro to 1.25 A resolution. Structures of pre- and postcleavage intermediates identify three catalytically relevant elements. The trapping of the putative catalytic water reveals its distinct roles as a base, acid, and nucleophile. The presentation of the substrate further explains the enigmatic latency of the protease, ensuring a single in cis cleavage. Additionally, we identified a zinc-free, disulfide-linked conformation of the TRASH motif, an interaction hub of immune factors. The structure opens additional opportunities in utilizing Npro as an autocleaving fusion protein and as a pharmaceutical target.	+
-		+
-	Crystal Structures of the Viral Protease Npro Imply Distinct Roles for the Catalytic Water in Catalysis.,Zogg T, Sponring M, Schindler S, Koll M, Schneider R, Brandstetter H, Auer B Structure. 2013 Apr 30. pii: ~~S0969-2126(13)00112-3. doi:, 10.1016~~/~~j.str.2013.04.003. PMID:23643950<ref>PMID:23643950<~~/~~ref>~~	+
-		+
-	~~From MEDLINE®/PubMed®, a database of the U~~.S. ~~National Library of Medicine.<br>~~	+
-	</~~div>~~	+
-	~~<div class="pdbe-citations 3zfn" style="background-color:#fffaf0;"><~~/~~div>~~	+

	==See Also==		==See Also==
	*[[Nonstructural protein 3D structures\|Nonstructural protein 3D structures]]		*[[Nonstructural protein 3D structures\|Nonstructural protein 3D structures]]
-	== References ==
-	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Pestivirus strain ~~d32~~/~~00_hobi~~]]	+	[[Category: Pestivirus strain D32/00_HoBi]]
-	[[Category: Auer, B]]	+	[[Category: Auer B]]
-	[[Category: Brandstetter, H]]	+	[[Category: Brandstetter H]]
-	[[Category: Koll, M]]	+	[[Category: Koll M]]
-	[[Category: Schindler, S]]	+	[[Category: Schindler S]]
-	[[Category: Schneider, R]]	+	[[Category: Schneider R]]
-	[[Category: Sponring, M]]	+	[[Category: Sponring M]]
-	[[Category: Zogg, T]]	+	[[Category: Zogg T]]
-	~~[[Category: Auto-processing cysteine protease]]~~	+
-	~~[[Category: Auto-proteolysis]]~~	+
-	~~[[Category: Convergent evolution]]~~	+
-	~~[[Category: Host-pathogen interaction]]~~	+
-	~~[[Category: Hydrolase]]~~	+
-	~~[[Category: Hydroxide-dependent catalysis]]~~	+
-	~~[[Category: Immune modulation]]~~	+
-	~~[[Category: In cis- cleavage]]~~	+
-	~~[[Category: Viral protease~~]]	+

OCA at 05:45, 10 August 2022

OCA — Wed, 10 Aug 2022 05:45:03 GMT

←Older revision		Revision as of 05:45, 10 August 2022
Line 1:		Line 1:

	==Crystal structure of product-like, processed N-terminal protease Npro==		==Crystal structure of product-like, processed N-terminal protease Npro==
-	<StructureSection load='3zfn' size='340' side='right' caption='[[3zfn]], [[Resolution\|resolution]] 1.50Å' scene=''>	+	<StructureSection load='3zfn' size='340' side='right'caption='[[3zfn]], [[Resolution\|resolution]] 1.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3zfn]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Pestivirus_strain_d32/00_hobi Pestivirus strain d32/00_hobi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZFN OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3ZFN FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3zfn]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pestivirus_strain_d32/00_hobi Pestivirus strain d32/00_hobi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZFN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3ZFN FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=SGM:MONOTHIOGLYCEROL'>SGM</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=SGM:MONOTHIOGLYCEROL'>SGM</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3zfo\|3zfo]], [[3zfp\|3zfp]], [[3zfq\|3zfq]], [[3zfr\|3zfr]], [[3zft\|3zft]], [[3zfu\|3zfu]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3zfo\|3zfo]], [[3zfp\|3zfp]], [[3zfq\|3zfq]], [[3zfr\|3zfr]], [[3zft\|3zft]], [[3zfu\|3zfu]]</div></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3zfn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zfn OCA], [~~http~~://pdbe.org/3zfn PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3zfn RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3zfn PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3zfn ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3zfn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zfn OCA], [https://pdbe.org/3zfn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3zfn RCSB], [https://www.ebi.ac.uk/pdbsum/3zfn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3zfn ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 19:		Line 19:

	==See Also==		==See Also==
-	*[[Nonstructural protein\|Nonstructural protein]]	+	*[[Nonstructural protein 3D structures\|Nonstructural protein 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Pestivirus strain d32/00_hobi]]		[[Category: Pestivirus strain d32/00_hobi]]
	[[Category: Auer, B]]		[[Category: Auer, B]]

OCA at 18:13, 4 August 2016

OCA — Thu, 04 Aug 2016 18:13:31 GMT

←Older revision		Revision as of 18:13, 4 August 2016
Line 1:		Line 1:
		+
	==Crystal structure of product-like, processed N-terminal protease Npro==		==Crystal structure of product-like, processed N-terminal protease Npro==
	<StructureSection load='3zfn' size='340' side='right' caption='[[3zfn]], [[Resolution\|resolution]] 1.50Å' scene=''>		<StructureSection load='3zfn' size='340' side='right' caption='[[3zfn]], [[Resolution\|resolution]] 1.50Å' scene=''>
Line 5:		Line 6:
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=SGM:MONOTHIOGLYCEROL'>SGM</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=SGM:MONOTHIOGLYCEROL'>SGM</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3zfo\|3zfo]], [[3zfp\|3zfp]], [[3zfq\|3zfq]], [[3zfr\|3zfr]], [[3zft\|3zft]], [[3zfu\|3zfu]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3zfo\|3zfo]], [[3zfp\|3zfp]], [[3zfq\|3zfq]], [[3zfr\|3zfr]], [[3zft\|3zft]], [[3zfu\|3zfu]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3zfn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zfn OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3zfn RCSB], [http://www.ebi.ac.uk/pdbsum/3zfn PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3zfn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zfn OCA], [http://pdbe.org/3zfn PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3zfn RCSB], [http://www.ebi.ac.uk/pdbsum/3zfn PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3zfn ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 15:		Line 16:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3zfn" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==

OCA at 09:11, 21 December 2014

OCA — Sun, 21 Dec 2014 09:11:56 GMT

←Older revision		Revision as of 09:11, 21 December 2014
Line 1:		Line 1:
-	~~{{STRUCTURE_3zfn\| PDB=3zfn \| SCENE= }}~~	+	==Crystal structure of product-like, processed N-terminal protease Npro==
-	===Crystal structure of product-like, processed N-terminal protease Npro===	+	<StructureSection load='3zfn' size='340' side='right' caption='[[3zfn]], [[Resolution\|resolution]] 1.50Å' scene=''>
-	~~{{ABSTRACT_PUBMED_23643950}}~~	+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[3zfn]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Pestivirus_strain_d32/00_hobi Pestivirus strain d32/00_hobi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZFN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ZFN FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=SGM:MONOTHIOGLYCEROL'>SGM</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3zfo\|3zfo]], [[3zfp\|3zfp]], [[3zfq\|3zfq]], [[3zfr\|3zfr]], [[3zft\|3zft]], [[3zfu\|3zfu]]</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3zfn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zfn OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3zfn RCSB], [http://www.ebi.ac.uk/pdbsum/3zfn PDBsum]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Npro is a key effector protein of pestiviruses such as bovine viral diarrhea virus and abolishes host cell antiviral defense mechanisms. Synthesized as the N-terminal part of the viral polyprotein, Npro releases itself via an autoproteolytic cleavage, triggering its immunological functions. However, the mechanisms of its proteolytic action and its immune escape were unclear. Here, we present the crystal structures of Npro to 1.25 A resolution. Structures of pre- and postcleavage intermediates identify three catalytically relevant elements. The trapping of the putative catalytic water reveals its distinct roles as a base, acid, and nucleophile. The presentation of the substrate further explains the enigmatic latency of the protease, ensuring a single in cis cleavage. Additionally, we identified a zinc-free, disulfide-linked conformation of the TRASH motif, an interaction hub of immune factors. The structure opens additional opportunities in utilizing Npro as an autocleaving fusion protein and as a pharmaceutical target.

-	~~==About this~~ Structure==	+	Crystal Structures of the Viral Protease Npro Imply Distinct Roles for the Catalytic Water in Catalysis.,Zogg T, Sponring M, Schindler S, Koll M, Schneider R, Brandstetter H, Auer B Structure. 2013 Apr 30. pii: S0969-2126(13)00112-3. doi:, 10.1016/j.str.2013.04.003. PMID:23643950<ref>PMID:23643950</ref>
-	~~[[3zfn]] is a 1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Pestivirus_strain_d32/00_hobi Pestivirus strain d32/00_hobi]~~. ~~Full crystallographic information is available from [http~~:/~~/oca~~.~~weizmann~~.ac.il/~~oca-bin/ocashort?id=3ZFN OCA].~~	+

-	==~~Reference~~==	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	~~<ref group~~=~~"xtra">PMID:023643950</ref>~~<references ~~group="xtra"~~/><~~references~~/>	+	</div>
		+
		+	==See Also==
		+	*[[Nonstructural protein\|Nonstructural protein]]
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
	[[Category: Pestivirus strain d32/00_hobi]]		[[Category: Pestivirus strain d32/00_hobi]]
-	[[Category: Auer, B.]]	+	[[Category: Auer, B]]
-	[[Category: Brandstetter, H.]]	+	[[Category: Brandstetter, H]]
-	[[Category: Koll, M.]]	+	[[Category: Koll, M]]
-	[[Category: Schindler, S.]]	+	[[Category: Schindler, S]]
-	[[Category: Schneider, R.]]	+	[[Category: Schneider, R]]
-	[[Category: Sponring, M.]]	+	[[Category: Sponring, M]]
-	[[Category: Zogg, T.]]	+	[[Category: Zogg, T]]
	[[Category: Auto-processing cysteine protease]]		[[Category: Auto-processing cysteine protease]]
	[[Category: Auto-proteolysis]]		[[Category: Auto-proteolysis]]

OCA at 07:42, 20 June 2013

OCA — Thu, 20 Jun 2013 07:42:15 GMT

←Older revision		Revision as of 07:42, 20 June 2013
Line 5:		Line 5:
	==About this Structure==		==About this Structure==
	[[3zfn]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Pestivirus_strain_d32/00_hobi Pestivirus strain d32/00_hobi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZFN OCA].		[[3zfn]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Pestivirus_strain_d32/00_hobi Pestivirus strain d32/00_hobi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZFN OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:023643950</ref><references group="xtra"/><references/>
	[[Category: Pestivirus strain d32/00_hobi]]		[[Category: Pestivirus strain d32/00_hobi]]
	[[Category: Auer, B.]]		[[Category: Auer, B.]]

OCA at 07:21, 16 May 2013

OCA — Thu, 16 May 2013 07:21:21 GMT

←Older revision		Revision as of 07:21, 16 May 2013
Line 1:		Line 1:
-	~~'''Unreleased~~ structure~~'''~~	+	{{STRUCTURE_3zfn\| PDB=3zfn \| SCENE= }}
		+	===Crystal structure of product-like, processed N-terminal protease Npro===
		+	{{ABSTRACT_PUBMED_23643950}}

-	~~The entry~~ 3zfn is ~~ON HOLD until Paper Publication~~	+	==About this Structure==
-		+	[[3zfn]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Pestivirus_strain_d32/00_hobi Pestivirus strain d32/00_hobi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZFN OCA].
-	~~Authors~~: ~~Zogg~~, T., ~~Sponring~~, M., Schindler, S.~~, Koll, M.,~~ Schneider, R., ~~Brandstetter, H~~., ~~Auer, B~~.	+	[[Category: Pestivirus strain d32/00_hobi]]
-		+	[[Category: Auer, B.]]
-	~~Description~~: ~~Crystal structure of product~~-~~like, processed N~~-~~terminal~~ protease ~~Npro~~	+	[[Category: Brandstetter, H.]]
		+	[[Category: Koll, M.]]
		+	[[Category: Schindler, S.]]
		+	[[Category: Schneider, R.]]
		+	[[Category: Sponring, M.]]
		+	[[Category: Zogg, T.]]
		+	[[Category: Auto-processing cysteine protease]]
		+	[[Category: Auto-proteolysis]]
		+	[[Category: Convergent evolution]]
		+	[[Category: Host-pathogen interaction]]
		+	[[Category: Hydrolase]]
		+	[[Category: Hydroxide-dependent catalysis]]
		+	[[Category: Immune modulation]]
		+	[[Category: In cis- cleavage]]
		+	[[Category: Viral protease]]

OCA at 08:38, 2 January 2013

OCA — Wed, 02 Jan 2013 08:38:37 GMT

←Older revision		Revision as of 08:38, 2 January 2013
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 3zfn is ON HOLD	+	The entry 3zfn is ON HOLD until Paper Publication

	Authors: Zogg, T., Sponring, M., Schindler, S., Koll, M., Schneider, R., Brandstetter, H., Auer, B.		Authors: Zogg, T., Sponring, M., Schindler, S., Koll, M., Schneider, R., Brandstetter, H., Auer, B.

	Description: Crystal structure of product-like, processed N-terminal protease Npro		Description: Crystal structure of product-like, processed N-terminal protease Npro

OCA: Protected "3zfn" [edit=sysop:move=sysop]

OCA — Wed, 19 Dec 2012 10:49:45 GMT

Protected "3zfn" [edit=sysop:move=sysop]

←Older revision

Revision as of 10:49, 19 December 2012

OCA: New page: '''Unreleased structure''' The entry 3zfn is ON HOLD Authors: Zogg, T., Sponring, M., Schindler, S., Koll, M., Schneider, R., Brandstetter, H., Auer, B. Description: Crystal structure ...

OCA — Wed, 19 Dec 2012 10:49:43 GMT

New page: '''Unreleased structure''' The entry 3zfn is ON HOLD Authors: Zogg, T., Sponring, M., Schindler, S., Koll, M., Schneider, R., Brandstetter, H., Auer, B. Description: Crystal structure ...

New page

'''Unreleased structure'''

The entry 3zfn is ON HOLD

Authors: Zogg, T., Sponring, M., Schindler, S., Koll, M., Schneider, R., Brandstetter, H., Auer, B.

Description: Crystal structure of product-like, processed N-terminal protease Npro