3zlf - Revision history

OCA at 11:05, 20 December 2023

OCA — Wed, 20 Dec 2023 11:05:12 GMT

←Older revision		Revision as of 11:05, 20 December 2023
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	<StructureSection load='3zlf' size='340' side='right'caption='[[3zlf]], [[Resolution\|resolution]] 2.15Å' scene=''>		<StructureSection load='3zlf' size='340' side='right'caption='[[3zlf]], [[Resolution\|resolution]] 2.15Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3zlf]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Strp6 Strp6~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZLF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3ZLF FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3zlf]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptococcus_pyogenes_MGAS10394 Streptococcus pyogenes MGAS10394]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZLF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3ZLF FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.15Å</td></tr>
-	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"~~><div style='overflow: auto; max-height: 3em;'>[[3zlg\|3zlg]], [[3zlh\|3zlh]]</div></td></tr>~~	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
-	~~<tr~~ id~~='activity'><td class~~="~~sblockLbl~~"><~~b>Activity:</b></td><td class~~=~~"sblockDat"><span class~~=~~'plainlinks~~'>~~[https://en.wikipedia.org/wiki/Phosphopyruvate_hydratase Phosphopyruvate hydratase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.11 4.2.1.11]~~ </~~span~~></td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3zlf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zlf OCA], [https://pdbe.org/3zlf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3zlf RCSB], [https://www.ebi.ac.uk/pdbsum/3zlf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3zlf ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3zlf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zlf OCA], [https://pdbe.org/3zlf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3zlf RCSB], [https://www.ebi.ac.uk/pdbsum/3zlf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3zlf ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/ENO_STRP6 ENO_STRP6]] Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis. Binds plasminogen when expressed on the bacterial cell surface, potentially allowing the bacterium to acquire surface-associated proteolytic activity, which in turn contributes to tissue invasion and virulence.<ref>PMID:9603964</ref>	+	[https://www.uniprot.org/uniprot/ENO_STRP6 ENO_STRP6] Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis. Binds plasminogen when expressed on the bacterial cell surface, potentially allowing the bacterium to acquire surface-associated proteolytic activity, which in turn contributes to tissue invasion and virulence.<ref>PMID:9603964</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Phosphopyruvate hydratase]]~~	+	[[Category: Streptococcus pyogenes MGAS10394]]
-	~~[[Category: Strp6~~]]	+	[[Category: Aquilina JA]]
-	[[Category: Aquilina~~, J A~~]]	+	[[Category: Bertozzi C]]
-	[[Category: Bertozzi, C]]	+	[[Category: Casey LW]]
-	[[Category: Casey~~, L W~~]]	+	[[Category: Cork AJ]]
-	[[Category: Cork~~, A J~~]]	+	[[Category: Ericsson DJ]]
-	[[Category: Ericsson~~, D J~~]]	+	[[Category: Kobe B]]
-	[[Category: Kobe, B]]	+	[[Category: Law RHP]]
-	[[Category: Law~~, R H.P~~]]	+	[[Category: Stamp A]]
-	[[Category: Stamp, A]]	+	[[Category: Valkov E]]
-	[[Category: Valkov, E]]	+	[[Category: Walker MJ]]
-	[[Category: Walker~~, M J~~]]	+	[[Category: Whisstock JC]]
-	[[Category: Whisstock~~, J C]]~~	+
-	~~[[Category: Lyase]]~~	+
-	~~[[Category: Plasminogen-binding~~]]	+

OCA at 05:50, 10 August 2022

OCA — Wed, 10 Aug 2022 05:50:36 GMT

←Older revision		Revision as of 05:50, 10 August 2022
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	==Structure of group A Streptococcal enolase K312A mutant==		==Structure of group A Streptococcal enolase K312A mutant==
-	<StructureSection load='3zlf' size='340' side='right' caption='[[3zlf]], [[Resolution\|resolution]] 2.15Å' scene=''>	+	<StructureSection load='3zlf' size='340' side='right'caption='[[3zlf]], [[Resolution\|resolution]] 2.15Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3zlf]] is a 4 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Strp6 Strp6]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZLF OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3ZLF FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3zlf]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Strp6 Strp6]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZLF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3ZLF FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3zlg\|3zlg]], [[3zlh\|3zlh]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3zlg\|3zlg]], [[3zlh\|3zlh]]</div></td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/Phosphopyruvate_hydratase Phosphopyruvate hydratase], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.11 4.2.1.11] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Phosphopyruvate_hydratase Phosphopyruvate hydratase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.11 4.2.1.11] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3zlf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zlf OCA], [~~http~~://pdbe.org/3zlf PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3zlf RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3zlf PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3zlf ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3zlf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zlf OCA], [https://pdbe.org/3zlf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3zlf RCSB], [https://www.ebi.ac.uk/pdbsum/3zlf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3zlf ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/ENO_STRP6 ENO_STRP6]] Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis. Binds plasminogen when expressed on the bacterial cell surface, potentially allowing the bacterium to acquire surface-associated proteolytic activity, which in turn contributes to tissue invasion and virulence.<ref>PMID:9603964</ref>	+	[[https://www.uniprot.org/uniprot/ENO_STRP6 ENO_STRP6]] Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis. Binds plasminogen when expressed on the bacterial cell surface, potentially allowing the bacterium to acquire surface-associated proteolytic activity, which in turn contributes to tissue invasion and virulence.<ref>PMID:9603964</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 22:		Line 22:

	==See Also==		==See Also==
-	*[[Enolase\|Enolase]]	+	*[[Enolase 3D structures\|Enolase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Phosphopyruvate hydratase]]		[[Category: Phosphopyruvate hydratase]]
	[[Category: Strp6]]		[[Category: Strp6]]

OCA at 17:22, 18 January 2017

OCA — Wed, 18 Jan 2017 17:22:22 GMT

←Older revision		Revision as of 17:22, 18 January 2017
Line 1:		Line 1:
		+
	==Structure of group A Streptococcal enolase K312A mutant==		==Structure of group A Streptococcal enolase K312A mutant==
	<StructureSection load='3zlf' size='340' side='right' caption='[[3zlf]], [[Resolution\|resolution]] 2.15Å' scene=''>		<StructureSection load='3zlf' size='340' side='right' caption='[[3zlf]], [[Resolution\|resolution]] 2.15Å' scene=''>
Line 6:		Line 7:
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3zlg\|3zlg]], [[3zlh\|3zlh]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3zlg\|3zlg]], [[3zlh\|3zlh]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Phosphopyruvate_hydratase Phosphopyruvate hydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.11 4.2.1.11] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Phosphopyruvate_hydratase Phosphopyruvate hydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.11 4.2.1.11] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3zlf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zlf OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3zlf RCSB], [http://www.ebi.ac.uk/pdbsum/3zlf PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3zlf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zlf OCA], [http://pdbe.org/3zlf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3zlf RCSB], [http://www.ebi.ac.uk/pdbsum/3zlf PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3zlf ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 18:		Line 19:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3zlf" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==

OCA at 05:37, 8 April 2015

OCA — Wed, 08 Apr 2015 05:37:34 GMT

←Older revision		Revision as of 05:37, 8 April 2015
Line 10:		Line 10:
	== Function ==		== Function ==
	[[http://www.uniprot.org/uniprot/ENO_STRP6 ENO_STRP6]] Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis. Binds plasminogen when expressed on the bacterial cell surface, potentially allowing the bacterium to acquire surface-associated proteolytic activity, which in turn contributes to tissue invasion and virulence.<ref>PMID:9603964</ref>		[[http://www.uniprot.org/uniprot/ENO_STRP6 ENO_STRP6]] Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis. Binds plasminogen when expressed on the bacterial cell surface, potentially allowing the bacterium to acquire surface-associated proteolytic activity, which in turn contributes to tissue invasion and virulence.<ref>PMID:9603964</ref>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Group A Streptococcus (GAS) is a human pathogen that has the potential to cause invasive disease by binding and activating human plasmin(ogen). Streptococcal surface enolase (SEN) is an octameric alpha-enolase that is localized at the GAS cell surface. In addition to its glycolytic role inside the cell, SEN functions as a receptor for plasmin(ogen) on the bacterial surface, but the understanding of the molecular basis of plasmin(ogen) binding is limited. In this study, we determined the crystal and solution structures of GAS SEN and characterized the increased plasminogen binding by two SEN mutants. The plasminogen binding ability of SENK312A and SENK362A is ~2- and ~3.4-fold greater than for the wild-type protein. A combination of thermal stability assays, native mass spectrometry and X-ray crystallography approaches shows that increased plasminogen binding ability correlates with decreased stability of the octamer. We propose that decreased stability of the octameric structure facilitates the access of plasmin(ogen) to its binding sites, leading to more efficient plasmin(ogen) binding and activation.
		+
		+	Stability of the octameric structure affects plasminogen-binding capacity of streptococcal enolase.,Cork AJ, Ericsson DJ, Law RH, Casey LW, Valkov E, Bertozzi C, Stamp A, Jovcevski B, Aquilina JA, Whisstock JC, Walker MJ, Kobe B PLoS One. 2015 Mar 25;10(3):e0121764. doi: 10.1371/journal.pone.0121764., eCollection 2015. PMID:25807546<ref>PMID:25807546</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>

	==See Also==		==See Also==

OCA at 13:00, 25 December 2014

OCA — Thu, 25 Dec 2014 13:00:24 GMT

←Older revision		Revision as of 13:00, 25 December 2014
Line 8:		Line 8:
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3zlf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zlf OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3zlf RCSB], [http://www.ebi.ac.uk/pdbsum/3zlf PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3zlf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zlf OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3zlf RCSB], [http://www.ebi.ac.uk/pdbsum/3zlf PDBsum]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/ENO_STRP6 ENO_STRP6]] Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis. Binds plasminogen when expressed on the bacterial cell surface, potentially allowing the bacterium to acquire surface-associated proteolytic activity, which in turn contributes to tissue invasion and virulence.<ref>PMID:9603964</ref>

	==See Also==		==See Also==
	*[[Enolase\|Enolase]]		*[[Enolase\|Enolase]]
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>

OCA at 18:34, 21 December 2014

OCA — Sun, 21 Dec 2014 18:34:31 GMT

←Older revision		Revision as of 18:34, 21 December 2014
Line 1:		Line 1:
-	~~{{STRUCTURE_3zlf\| PDB=3zlf \| SCENE= }}~~	+	==Structure of group A Streptococcal enolase K312A mutant==
-	===Structure of group A Streptococcal enolase K312A mutant===	+	<StructureSection load='3zlf' size='340' side='right' caption='[[3zlf]], [[Resolution\|resolution]] 2.15Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[3zlf]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Strp6 Strp6]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZLF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ZLF FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3zlg\|3zlg]], [[3zlh\|3zlh]]</td></tr>
		+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Phosphopyruvate_hydratase Phosphopyruvate hydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.11 4.2.1.11] </span></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3zlf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zlf OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3zlf RCSB], [http://www.ebi.ac.uk/pdbsum/3zlf PDBsum]</span></td></tr>
		+	</table>

-	==~~Function~~==	+	==See Also==
-	[[~~http://www.uniprot.org/uniprot/ENO_STRP6 ENO_STRP6~~]] Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis. Binds plasminogen when expressed on the bacterial cell surface, potentially allowing the bacterium to acquire surface-associated proteolytic activity, which in turn contributes to tissue invasion and virulence.<ref>PMID:9603964</ref>	+	*[[Enolase\|Enolase]]
-		+	__TOC__
-	~~==About this Structure==~~	+	</StructureSection>
-	~~[[3zlf]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZLF OCA].~~	+
-		+
-	~~==Reference==~~	+
-	~~<references group="xtra"/>~~<~~references~~/>	+
	[[Category: Phosphopyruvate hydratase]]		[[Category: Phosphopyruvate hydratase]]
-	[[Category: Aquilina, J A.]]	+	[[Category: Strp6]]
-	[[Category: Bertozzi, C.]]	+	[[Category: Aquilina, J A]]
-	[[Category: Casey, L W.]]	+	[[Category: Bertozzi, C]]
-	[[Category: Cork, A J.]]	+	[[Category: Casey, L W]]
-	[[Category: Ericsson, D J.]]	+	[[Category: Cork, A J]]
-	[[Category: Kobe, B.]]	+	[[Category: Ericsson, D J]]
-	[[Category: Law, R H.P.]]	+	[[Category: Kobe, B]]
-	[[Category: Stamp, A.]]	+	[[Category: Law, R H.P]]
-	[[Category: Valkov, E.]]	+	[[Category: Stamp, A]]
-	[[Category: Walker, M J.]]	+	[[Category: Valkov, E]]
-	[[Category: Whisstock, J C.]]	+	[[Category: Walker, M J]]
		+	[[Category: Whisstock, J C]]
	[[Category: Lyase]]		[[Category: Lyase]]
	[[Category: Plasminogen-binding]]		[[Category: Plasminogen-binding]]

OCA at 11:28, 5 February 2014

OCA — Wed, 05 Feb 2014 11:28:39 GMT

←Older revision		Revision as of 11:28, 5 February 2014
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	{{STRUCTURE_3zlf\| PDB=3zlf \| SCENE= }}
		+	===Structure of group A Streptococcal enolase K312A mutant===

-	~~The entry 3zlf~~ is ~~ON HOLD~~ ~~until Paper Publication~~	+	==Function==
		+	[[http://www.uniprot.org/uniprot/ENO_STRP6 ENO_STRP6]] Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis. Binds plasminogen when expressed on the bacterial cell surface, potentially allowing the bacterium to acquire surface-associated proteolytic activity, which in turn contributes to tissue invasion and virulence.<ref>PMID:9603964</ref>

-	~~Authors~~: ~~Cork, A.J., Ericsson, D.J., Law, R.H.P., Casey, L.W., Valkov, E., Bertozzi, C., Stamp, A., Aquilina, J.A., Whisstock, J.C~~.~~, Walker, M~~.J.~~, Kobe, B~~.	+	==About this Structure==
		+	[[3zlf]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZLF OCA].

-	~~Description: Structure of~~ group A ~~Streptococcal enolase K312A mutant~~	+	==Reference==
		+	<references group="xtra"/><references/>
		+	[[Category: Phosphopyruvate hydratase]]
		+	[[Category: Aquilina, J A.]]
		+	[[Category: Bertozzi, C.]]
		+	[[Category: Casey, L W.]]
		+	[[Category: Cork, A J.]]
		+	[[Category: Ericsson, D J.]]
		+	[[Category: Kobe, B.]]
		+	[[Category: Law, R H.P.]]
		+	[[Category: Stamp, A.]]
		+	[[Category: Valkov, E.]]
		+	[[Category: Walker, M J.]]
		+	[[Category: Whisstock, J C.]]
		+	[[Category: Lyase]]
		+	[[Category: Plasminogen-binding]]

OCA at 09:52, 13 February 2013

OCA — Wed, 13 Feb 2013 09:52:56 GMT

←Older revision		Revision as of 09:52, 13 February 2013
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 3zlf is ON HOLD	+	The entry 3zlf is ON HOLD until Paper Publication

-	Authors: Cork, A.J., Ericsson, D., Law, R.H.P., Casey, L., Valkov, E., Bertozzi, C., Stamp, A., Aquilina, J.A., Whisstock, J.C., Walker, M.J., Kobe, B.	+	Authors: Cork, A.J., Ericsson, D.J., Law, R.H.P., Casey, L.W., Valkov, E., Bertozzi, C., Stamp, A., Aquilina, J.A., Whisstock, J.C., Walker, M.J., Kobe, B.

	Description: Structure of group A Streptococcal enolase K312A mutant		Description: Structure of group A Streptococcal enolase K312A mutant

OCA: Protected "3zlf" [edit=sysop:move=sysop]

OCA — Wed, 06 Feb 2013 12:16:17 GMT

Protected "3zlf" [edit=sysop:move=sysop]

←Older revision

Revision as of 12:16, 6 February 2013

OCA: New page: '''Unreleased structure''' The entry 3zlf is ON HOLD Authors: Cork, A.J., Ericsson, D., Law, R.H.P., Casey, L., Valkov, E., Bertozzi, C., Stamp, A., Aquilina, J.A., Whisstock, J.C., Wal...

OCA — Wed, 06 Feb 2013 12:16:16 GMT

New page: '''Unreleased structure''' The entry 3zlf is ON HOLD Authors: Cork, A.J., Ericsson, D., Law, R.H.P., Casey, L., Valkov, E., Bertozzi, C., Stamp, A., Aquilina, J.A., Whisstock, J.C., Wal...

New page

'''Unreleased structure'''

The entry 3zlf is ON HOLD

Authors: Cork, A.J., Ericsson, D., Law, R.H.P., Casey, L., Valkov, E., Bertozzi, C., Stamp, A., Aquilina, J.A., Whisstock, J.C., Walker, M.J., Kobe, B.

Description: Structure of group A Streptococcal enolase K312A mutant