3zmh - Revision history

OCA at 11:06, 20 December 2023

OCA — Wed, 20 Dec 2023 11:06:08 GMT

←Older revision		Revision as of 11:06, 20 December 2023
Line 3:		Line 3:
	<StructureSection load='3zmh' size='340' side='right'caption='[[3zmh]], [[Resolution\|resolution]] 2.30Å' scene=''>		<StructureSection load='3zmh' size='340' side='right'caption='[[3zmh]], [[Resolution\|resolution]] 2.30Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3zmh]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~"bacillus_coli"_migula_1895 "bacillus~~ coli~~" migula 1895~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZMH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3ZMH FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3zmh]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZMH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3ZMH FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=78C:CYCLOPENTYL+2-OXO-4-PHENYLAZETIDINE-1-CARBOXYLATE'>78C</scene>, <scene name='pdbligand=BNG:B-NONYLGLUCOSIDE'>BNG</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=L62:CYCLOPENTYL+N-[(1R)-3-OXIDANYLIDENE-1-PHENYL-PROPYL]CARBAMATE'>L62</scene~~></td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.3Å</td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3zmi\|3zmi]], [[3zmj\|3zmj]], [[3zot\|3zot]]</div></td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=78C:CYCLOPENTYL+2-OXO-4-PHENYLAZETIDINE-1-CARBOXYLATE'>78C</scene>, <scene name='pdbligand=BNG:B-NONYLGLUCOSIDE'>BNG</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=L62:CYCLOPENTYL+N-[(1R)-3-OXIDANYLIDENE-1-PHENYL-PROPYL]CARBAMATE'>L62</scene></td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Rhomboid_protease Rhomboid protease], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.105 3.4.21.105] </span></td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3zmh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zmh OCA], [https://pdbe.org/3zmh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3zmh RCSB], [https://www.ebi.ac.uk/pdbsum/3zmh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3zmh ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3zmh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zmh OCA], [https://pdbe.org/3zmh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3zmh RCSB], [https://www.ebi.ac.uk/pdbsum/3zmh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3zmh ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/GLPG_ECOLI GLPG_ECOLI]] Rhomboid-type serine protease that catalyzes intramembrane proteolysis.<ref>PMID:17099694</ref> <ref>PMID:16216077</ref>	+	[https://www.uniprot.org/uniprot/GLPG_ECOLI GLPG_ECOLI] Rhomboid-type serine protease that catalyzes intramembrane proteolysis.<ref>PMID:17099694</ref> <ref>PMID:16216077</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 27:		Line 26:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Bacillus~~ coli ~~migula 1895~~]]	+	[[Category: Escherichia coli]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	~~[[Category: Rhomboid protease]]~~	+	[[Category: Freeman M]]
-	[[Category: Freeman, M]]	+	[[Category: Large JM]]
-	[[Category: Large~~, J M~~]]	+	[[Category: Pierrat OA]]
-	[[Category: Pierrat~~, O A~~]]	+	[[Category: Vinothkumar KR]]
-	[[Category: Vinothkumar~~, K R]]~~	+
-	~~[[Category: Acyl enzyme]]~~	+
-	~~[[Category: Anitbiotic]]~~	+
-	~~[[Category: Beta lactam]]~~	+
-	~~[[Category: Hydrolase]]~~	+
-	~~[[Category: Intra-membrane protease~~]]	+

OCA at 07:01, 18 August 2022

OCA — Thu, 18 Aug 2022 07:01:18 GMT

←Older revision		Revision as of 07:01, 18 August 2022
Line 1:		Line 1:

	==Structure of E.coli rhomboid protease GlpG in complex with monobactam L62==		==Structure of E.coli rhomboid protease GlpG in complex with monobactam L62==
-	<StructureSection load='3zmh' size='340' side='right' caption='[[3zmh]], [[Resolution\|resolution]] 2.30Å' scene=''>	+	<StructureSection load='3zmh' size='340' side='right'caption='[[3zmh]], [[Resolution\|resolution]] 2.30Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3zmh]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZMH OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3ZMH FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3zmh]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZMH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3ZMH FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=78C:CYCLOPENTYL+2-OXO-4-PHENYLAZETIDINE-1-CARBOXYLATE'>78C</scene>, <scene name='pdbligand=BNG:B-NONYLGLUCOSIDE'>BNG</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=L62:CYCLOPENTYL+N-[(1R)-3-OXIDANYLIDENE-1-PHENYL-PROPYL]CARBAMATE'>L62</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=78C:CYCLOPENTYL+2-OXO-4-PHENYLAZETIDINE-1-CARBOXYLATE'>78C</scene>, <scene name='pdbligand=BNG:B-NONYLGLUCOSIDE'>BNG</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=L62:CYCLOPENTYL+N-[(1R)-3-OXIDANYLIDENE-1-PHENYL-PROPYL]CARBAMATE'>L62</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3zmi\|3zmi]], [[3zmj\|3zmj]], [[3zot\|3zot]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3zmi\|3zmi]], [[3zmj\|3zmj]], [[3zot\|3zot]]</div></td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/Rhomboid_protease Rhomboid protease], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.105 3.4.21.105] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Rhomboid_protease Rhomboid protease], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.105 3.4.21.105] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3zmh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zmh OCA], [~~http~~://pdbe.org/3zmh PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3zmh RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3zmh PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3zmh ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3zmh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zmh OCA], [https://pdbe.org/3zmh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3zmh RCSB], [https://www.ebi.ac.uk/pdbsum/3zmh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3zmh ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/GLPG_ECOLI GLPG_ECOLI]] Rhomboid-type serine protease that catalyzes intramembrane proteolysis.<ref>PMID:17099694</ref> <ref>PMID:16216077</ref>	+	[[https://www.uniprot.org/uniprot/GLPG_ECOLI GLPG_ECOLI]] Rhomboid-type serine protease that catalyzes intramembrane proteolysis.<ref>PMID:17099694</ref> <ref>PMID:16216077</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 28:		Line 28:
	</StructureSection>		</StructureSection>
	[[Category: Bacillus coli migula 1895]]		[[Category: Bacillus coli migula 1895]]
		+	[[Category: Large Structures]]
	[[Category: Rhomboid protease]]		[[Category: Rhomboid protease]]
	[[Category: Freeman, M]]		[[Category: Freeman, M]]

OCA at 10:21, 4 August 2016

OCA — Thu, 04 Aug 2016 10:21:06 GMT

←Older revision		Revision as of 10:21, 4 August 2016
Line 1:		Line 1:
		+
	==Structure of E.coli rhomboid protease GlpG in complex with monobactam L62==		==Structure of E.coli rhomboid protease GlpG in complex with monobactam L62==
	<StructureSection load='3zmh' size='340' side='right' caption='[[3zmh]], [[Resolution\|resolution]] 2.30Å' scene=''>		<StructureSection load='3zmh' size='340' side='right' caption='[[3zmh]], [[Resolution\|resolution]] 2.30Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3zmh]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Escherichia_coli Escherichia~~ coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZMH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ZMH FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3zmh]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZMH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ZMH FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=78C:CYCLOPENTYL+2-OXO-4-PHENYLAZETIDINE-1-CARBOXYLATE'>78C</scene>, <scene name='pdbligand=BNG:B-NONYLGLUCOSIDE'>BNG</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=L62:CYCLOPENTYL+N-[(1R)-3-OXIDANYLIDENE-1-PHENYL-PROPYL]CARBAMATE'>L62</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=78C:CYCLOPENTYL+2-OXO-4-PHENYLAZETIDINE-1-CARBOXYLATE'>78C</scene>, <scene name='pdbligand=BNG:B-NONYLGLUCOSIDE'>BNG</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=L62:CYCLOPENTYL+N-[(1R)-3-OXIDANYLIDENE-1-PHENYL-PROPYL]CARBAMATE'>L62</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3zmi\|3zmi]], [[3zmj\|3zmj]], [[3zot\|3zot]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3zmi\|3zmi]], [[3zmj\|3zmj]], [[3zot\|3zot]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Rhomboid_protease Rhomboid protease], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.105 3.4.21.105] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Rhomboid_protease Rhomboid protease], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.105 3.4.21.105] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3zmh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zmh OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3zmh RCSB], [http://www.ebi.ac.uk/pdbsum/3zmh PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3zmh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zmh OCA], [http://pdbe.org/3zmh PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3zmh RCSB], [http://www.ebi.ac.uk/pdbsum/3zmh PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3zmh ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 18:		Line 19:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3zmh" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 25:		Line 27:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Escherichia~~ coli]]	+	[[Category: Bacillus coli migula 1895]]
	[[Category: Rhomboid protease]]		[[Category: Rhomboid protease]]
	[[Category: Freeman, M]]		[[Category: Freeman, M]]

OCA at 08:52, 24 December 2014

OCA — Wed, 24 Dec 2014 08:52:02 GMT

←Older revision		Revision as of 08:52, 24 December 2014
Line 1:		Line 1:
-	~~{{STRUCTURE_3zmh\| PDB=3zmh \| SCENE= }}~~	+	==Structure of E.coli rhomboid protease GlpG in complex with monobactam L62==
-	===Structure of E.coli rhomboid protease GlpG in complex with monobactam L62===	+	<StructureSection load='3zmh' size='340' side='right' caption='[[3zmh]], [[Resolution\|resolution]] 2.30Å' scene=''>
-	~~{{ABSTRACT_PUBMED_23665170}}~~	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[3zmh]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZMH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ZMH FirstGlance]. <br>
-	==Function==	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=78C:CYCLOPENTYL+2-OXO-4-PHENYLAZETIDINE-1-CARBOXYLATE'>78C</scene>, <scene name='pdbligand=BNG:B-NONYLGLUCOSIDE'>BNG</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=L62:CYCLOPENTYL+N-[(1R)-3-OXIDANYLIDENE-1-PHENYL-PROPYL]CARBAMATE'>L62</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3zmi\|3zmi]], [[3zmj\|3zmj]], [[3zot\|3zot]]</td></tr>
		+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Rhomboid_protease Rhomboid protease], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.105 3.4.21.105] </span></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3zmh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zmh OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3zmh RCSB], [http://www.ebi.ac.uk/pdbsum/3zmh PDBsum]</span></td></tr>
		+	</table>
		+	== Function ==
	[[http://www.uniprot.org/uniprot/GLPG_ECOLI GLPG_ECOLI]] Rhomboid-type serine protease that catalyzes intramembrane proteolysis.<ref>PMID:17099694</ref> <ref>PMID:16216077</ref>		[[http://www.uniprot.org/uniprot/GLPG_ECOLI GLPG_ECOLI]] Rhomboid-type serine protease that catalyzes intramembrane proteolysis.<ref>PMID:17099694</ref> <ref>PMID:16216077</ref>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Rhomboids are evolutionarily conserved serine proteases that cleave transmembrane proteins within the membrane. The increasing number of known rhomboid functions in prokaryotes and eukaryotes makes them attractive drug targets. Here, we describe structures of the Escherichia coli rhomboid GlpG in complex with beta-lactam inhibitors. The inhibitors form a single bond to the catalytic serine and the carbonyl oxygen of the inhibitor faces away from the oxyanion hole. The hydrophobic N-substituent of beta-lactam inhibitors points into a cavity within the enzyme, providing a structural explanation for the specificity of beta-lactams on rhomboid proteases. This same cavity probably represents the S2' substrate binding site of GlpG. We suggest that the structural changes in beta-lactam inhibitor binding reflect the state of the enzyme at an initial stage of substrate binding to the active site. The structural insights from these enzyme-inhibitor complexes provide a starting point for structure-based design for rhomboid inhibitors.

-	~~==About this~~ Structure==	+	Structure of Rhomboid Protease in Complex with beta-Lactam Inhibitors Defines the S2' Cavity.,Vinothkumar KR, Pierrat OA, Large JM, Freeman M Structure. 2013 May 7. pii: S0969-2126(13)00117-2. doi:, 10.1016/j.str.2013.03.013. PMID:23665170<ref>PMID:23665170</ref>
-	~~[[3zmh]] is a 1 chain structure~~ with ~~sequence from [http~~:~~//en~~.~~wikipedia~~.~~org~~/~~wiki/Escherichia_coli Escherichia coli]~~. ~~Full crystallographic information is available from [http~~://~~oca~~.~~weizmann~~.ac.il/~~oca-bin/ocashort?id=3ZMH OCA].~~	+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>

	==See Also==		==See Also==
	*[[Rhomboid protease\|Rhomboid protease]]		*[[Rhomboid protease\|Rhomboid protease]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	~~<ref group="xtra">PMID:023665170</ref>~~<references ~~group="xtra"~~/><~~references~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
	[[Category: Rhomboid protease]]		[[Category: Rhomboid protease]]
-	[[Category: Freeman, M.]]	+	[[Category: Freeman, M]]
-	[[Category: Large, J M.]]	+	[[Category: Large, J M]]
-	[[Category: Pierrat, O A.]]	+	[[Category: Pierrat, O A]]
-	[[Category: Vinothkumar, K R.]]	+	[[Category: Vinothkumar, K R]]
	[[Category: Acyl enzyme]]		[[Category: Acyl enzyme]]
	[[Category: Anitbiotic]]		[[Category: Anitbiotic]]

OCA at 04:57, 28 August 2013

OCA — Wed, 28 Aug 2013 04:57:26 GMT

←Older revision		Revision as of 04:57, 28 August 2013
Line 8:		Line 8:
	==About this Structure==		==About this Structure==
	[[3zmh]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZMH OCA].		[[3zmh]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZMH OCA].
		+
		+	==See Also==
		+	*[[Rhomboid protease\|Rhomboid protease]]

	==Reference==		==Reference==

OCA at 16:28, 19 June 2013

OCA — Wed, 19 Jun 2013 16:28:52 GMT

←Older revision		Revision as of 16:28, 19 June 2013
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	{{STRUCTURE_3zmh\| PDB=3zmh \| SCENE= }}
		+	===Structure of E.coli rhomboid protease GlpG in complex with monobactam L62===
		+	{{ABSTRACT_PUBMED_23665170}}

-	~~The entry 3zmh is ON HOLD~~ ~~until Paper Publication~~	+	==Function==
		+	[[http://www.uniprot.org/uniprot/GLPG_ECOLI GLPG_ECOLI]] Rhomboid-type serine protease that catalyzes intramembrane proteolysis.<ref>PMID:17099694</ref> <ref>PMID:16216077</ref>

-	~~Authors~~: ~~Vinothkumar, K~~.R.~~, Pierrat, O~~.A.~~, Large, J~~.M.~~, Freeman, M~~.	+	==About this Structure==
		+	[[3zmh]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZMH OCA].

-	~~Description~~: ~~Structure of E.~~coli ~~rhomboid~~ protease ~~GlpG in complex with monobactam L62~~	+	==Reference==
		+	<ref group="xtra">PMID:023665170</ref><references group="xtra"/><references/>
		+	[[Category: Escherichia coli]]
		+	[[Category: Rhomboid protease]]
		+	[[Category: Freeman, M.]]
		+	[[Category: Large, J M.]]
		+	[[Category: Pierrat, O A.]]
		+	[[Category: Vinothkumar, K R.]]
		+	[[Category: Acyl enzyme]]
		+	[[Category: Anitbiotic]]
		+	[[Category: Beta lactam]]
		+	[[Category: Hydrolase]]
		+	[[Category: Intra-membrane protease]]

OCA at 19:39, 17 April 2013

OCA — Wed, 17 Apr 2013 19:39:45 GMT

←Older revision		Revision as of 19:39, 17 April 2013
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 3zmh is ON HOLD	+	The entry 3zmh is ON HOLD until Paper Publication

	Authors: Vinothkumar, K.R., Pierrat, O.A., Large, J.M., Freeman, M.		Authors: Vinothkumar, K.R., Pierrat, O.A., Large, J.M., Freeman, M.

	Description: Structure of E.coli rhomboid protease GlpG in complex with monobactam L62		Description: Structure of E.coli rhomboid protease GlpG in complex with monobactam L62

OCA: Protected "3zmh" [edit=sysop:move=sysop]

OCA — Wed, 20 Feb 2013 13:12:42 GMT

Protected "3zmh" [edit=sysop:move=sysop]

←Older revision

Revision as of 13:12, 20 February 2013

OCA: New page: '''Unreleased structure''' The entry 3zmh is ON HOLD Authors: Vinothkumar, K.R., Pierrat, O.A., Large, J.M., Freeman, M. Description: Structure of E.coli rhomboid protease GlpG in comp...

OCA — Wed, 20 Feb 2013 13:12:41 GMT

New page: '''Unreleased structure''' The entry 3zmh is ON HOLD Authors: Vinothkumar, K.R., Pierrat, O.A., Large, J.M., Freeman, M. Description: Structure of E.coli rhomboid protease GlpG in comp...

New page

'''Unreleased structure'''

The entry 3zmh is ON HOLD

Authors: Vinothkumar, K.R., Pierrat, O.A., Large, J.M., Freeman, M.

Description: Structure of E.coli rhomboid protease GlpG in complex with monobactam L62