3zo7 - Revision history

OCA at 10:41, 9 May 2024

OCA — Thu, 09 May 2024 10:41:46 GMT

←Older revision		Revision as of 10:41, 9 May 2024
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	<StructureSection load='3zo7' size='340' side='right'caption='[[3zo7]], [[Resolution\|resolution]] 2.22Å' scene=''>		<StructureSection load='3zo7' size='340' side='right'caption='[[3zo7]], [[Resolution\|resolution]] 2.22Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3zo7]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/~~"nocardia_opaca"_aggag_and_schlegel_1973 "nocardia opaca" aggag and schlegel 1973~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZO7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3ZO7 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3zo7]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Rhodococcus_opacus Rhodococcus opacus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZO7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3ZO7 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=K6H:(2S)-2-CHLORANYL-2-[(2R)-5-OXIDANYLIDENE-2H-FURAN-2-YL]ETHANOIC+ACID'>K6H</scene~~></td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.224Å</td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3znj\|3znj]], [[3znu\|3znu]]</div~~></td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=K6H:(2S)-2-CHLORANYL-2-[(2R)-5-OXIDANYLIDENE-2H-FURAN-2-YL]ETHANOIC+ACID'>K6H</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3zo7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zo7 OCA], [https://pdbe.org/3zo7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3zo7 RCSB], [https://www.ebi.ac.uk/pdbsum/3zo7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3zo7 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3zo7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zo7 OCA], [https://pdbe.org/3zo7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3zo7 RCSB], [https://www.ebi.ac.uk/pdbsum/3zo7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3zo7 ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/Q8G9L0_RHOOP Q8G9L0_RHOOP]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 24:		Line 26:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Nocardia opaca aggag and schlegel 1973]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Groening~~, J A.D~~]]	+	[[Category: Rhodococcus opacus]]
-	[[Category: Kaschabek~~, S R~~]]	+	[[Category: Groening JAD]]
-	[[Category: Roth, C]]	+	[[Category: Kaschabek SR]]
-	[[Category: Schloemann, M]]	+	[[Category: Roth C]]
-	[[Category: Straeter, N]]	+	[[Category: Schloemann M]]
-	~~[[Category: Chlorocatechol pathway]]~~	+	[[Category: Straeter N]]
-	~~[[Category: Dehalogenase]]~~	+
-	~~[[Category: Ferredoxin fold]]~~	+
-	~~[[Category: Lyase~~]]	+

OCA at 07:04, 18 August 2022

OCA — Thu, 18 Aug 2022 07:04:51 GMT

←Older revision		Revision as of 07:04, 18 August 2022
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	==Crystal structure of ClcFE27A with substrate==		==Crystal structure of ClcFE27A with substrate==
-	<StructureSection load='3zo7' size='340' side='right' caption='[[3zo7]], [[Resolution\|resolution]] 2.22Å' scene=''>	+	<StructureSection load='3zo7' size='340' side='right'caption='[[3zo7]], [[Resolution\|resolution]] 2.22Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3zo7]] is a 10 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/"nocardia_opaca"_aggag_and_schlegel_1973 "nocardia opaca" aggag and schlegel 1973]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZO7 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3ZO7 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3zo7]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/"nocardia_opaca"_aggag_and_schlegel_1973 "nocardia opaca" aggag and schlegel 1973]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZO7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3ZO7 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=K6H:(2S)-2-CHLORANYL-2-[(2R)-5-OXIDANYLIDENE-2H-FURAN-2-YL]ETHANOIC+ACID'>K6H</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=K6H:(2S)-2-CHLORANYL-2-[(2R)-5-OXIDANYLIDENE-2H-FURAN-2-YL]ETHANOIC+ACID'>K6H</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3znj\|3znj]], [[3znu\|3znu]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3znj\|3znj]], [[3znu\|3znu]]</div></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3zo7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zo7 OCA], [~~http~~://pdbe.org/3zo7 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3zo7 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3zo7 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3zo7 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3zo7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zo7 OCA], [https://pdbe.org/3zo7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3zo7 RCSB], [https://www.ebi.ac.uk/pdbsum/3zo7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3zo7 ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 19:		Line 19:

	==See Also==		==See Also==
-	*[[Dehalogenase\|Dehalogenase]]	+	*[[Dehalogenase 3D structures\|Dehalogenase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 25:		Line 25:
	</StructureSection>		</StructureSection>
	[[Category: Nocardia opaca aggag and schlegel 1973]]		[[Category: Nocardia opaca aggag and schlegel 1973]]
		+	[[Category: Large Structures]]
	[[Category: Groening, J A.D]]		[[Category: Groening, J A.D]]
	[[Category: Kaschabek, S R]]		[[Category: Kaschabek, S R]]

OCA at 13:56, 11 August 2016

OCA — Thu, 11 Aug 2016 13:56:04 GMT

←Older revision		Revision as of 13:56, 11 August 2016
Line 1:		Line 1:
		+
	==Crystal structure of ClcFE27A with substrate==		==Crystal structure of ClcFE27A with substrate==
	<StructureSection load='3zo7' size='340' side='right' caption='[[3zo7]], [[Resolution\|resolution]] 2.22Å' scene=''>		<StructureSection load='3zo7' size='340' side='right' caption='[[3zo7]], [[Resolution\|resolution]] 2.22Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3zo7]] is a 10 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Rhodococcus_opacus Rhodococcus opacus~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZO7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ZO7 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3zo7]] is a 10 chain structure with sequence from [http://en.wikipedia.org/wiki/"nocardia_opaca"_aggag_and_schlegel_1973 "nocardia opaca" aggag and schlegel 1973]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZO7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ZO7 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=K6H:(2S)-2-CHLORANYL-2-[(2R)-5-OXIDANYLIDENE-2H-FURAN-2-YL]ETHANOIC+ACID'>K6H</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=K6H:(2S)-2-CHLORANYL-2-[(2R)-5-OXIDANYLIDENE-2H-FURAN-2-YL]ETHANOIC+ACID'>K6H</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3znj\|3znj]], [[3znu\|3znu]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3znj\|3znj]], [[3znu\|3znu]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3zo7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zo7 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3zo7 RCSB], [http://www.ebi.ac.uk/pdbsum/3zo7 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3zo7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zo7 OCA], [http://pdbe.org/3zo7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3zo7 RCSB], [http://www.ebi.ac.uk/pdbsum/3zo7 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3zo7 ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 15:		Line 16:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3zo7" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 22:		Line 24:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Rhodococcus opacus~~]]	+	[[Category: Nocardia opaca aggag and schlegel 1973]]
	[[Category: Groening, J A.D]]		[[Category: Groening, J A.D]]
	[[Category: Kaschabek, S R]]		[[Category: Kaschabek, S R]]

OCA at 10:57, 4 January 2015

OCA — Sun, 04 Jan 2015 10:57:59 GMT

←Older revision		Revision as of 10:57, 4 January 2015
Line 1:		Line 1:
-	~~{{STRUCTURE_3zo7\| PDB~~=3zo7 \| ~~SCENE~~= }}	+	==Crystal structure of ClcFE27A with substrate==
-	===~~Crystal~~ structure ~~of ClcFE27A~~ with ~~substrate~~===	+	<StructureSection load='3zo7' size='340' side='right' caption='[[3zo7]], [[Resolution\|resolution]] 2.22Å' scene=''>
-	~~{{ABSTRACT_PUBMED_23421784}}~~	+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[3zo7]] is a 10 chain structure with sequence from [http://en.wikipedia.org/wiki/Rhodococcus_opacus Rhodococcus opacus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZO7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ZO7 FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=K6H:(2S)-2-CHLORANYL-2-[(2R)-5-OXIDANYLIDENE-2H-FURAN-2-YL]ETHANOIC+ACID'>K6H</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3znj\|3znj]], [[3znu\|3znu]]</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3zo7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zo7 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3zo7 RCSB], [http://www.ebi.ac.uk/pdbsum/3zo7 PDBsum]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The actinobacterium Rhodococcus opacus 1CP possesses a so far unique variant of the modified 3-oxoadipate pathway for 3-chlorocatechol degradation. One important feature is the novel dehalogenase ClcF, which converts (4R,5S) 5-chloromuconolactone to E-dienelactone. ClcF is related to muconolactone isomerase (MLI, EC 5.3.3.4). The enzyme has a ferredoxin-type fold and forms a homodecamer of 52-symmetry, typical for the MLI family. The active site is formed by residues from two monomers. The complex structure of an E27A variant with bound substrate in conjunction with mutational studies indicate that E27 acts as the proton acceptor in a univalent single-base syn-dehydrohalogenation mechanism. Despite the evolutionary specialisation of ClcF, the conserved active site structures suggest that the proposed mechanism is representative for the MLI family. Furthermore, ClcF represents a novel type of dehalogenase based on an isomerase scaffold.

-	~~==About this Structure==~~	+	Crystal structure and catalytic mechanism of chloromuconolactone dehalogenase ClcF from Rhodococcus opacus 1CP.,Roth C, Janosch AD, Kaschabek SR, Schlomann M, Strater N Mol Microbiol. 2013 Feb 20. doi: 10.1111/mmi.12182. PMID:23421784<ref>PMID:23421784</ref>
-	~~[[3zo7]] is a 10 chain~~ structure ~~with sequence~~ from ~~[http://en~~.~~wikipedia~~.~~org~~/~~wiki/Rhodococcus_opacus Rhodococcus opacus]~~. ~~Full crystallographic information is available from [http~~://~~oca~~.~~weizmann~~.ac.il/~~oca-bin/ocashort?id~~=~~3ZO7 OCA~~].	+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+
		+	==See Also==
		+	*[[Dehalogenase\|Dehalogenase]]
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
	[[Category: Rhodococcus opacus]]		[[Category: Rhodococcus opacus]]
-	[[Category: Groening, J A.D.]]	+	[[Category: Groening, J A.D]]
-	[[Category: Kaschabek, S R.]]	+	[[Category: Kaschabek, S R]]
-	[[Category: Roth, C.]]	+	[[Category: Roth, C]]
-	[[Category: Schloemann, M.]]	+	[[Category: Schloemann, M]]
-	[[Category: Straeter, N.]]	+	[[Category: Straeter, N]]
	[[Category: Chlorocatechol pathway]]		[[Category: Chlorocatechol pathway]]
	[[Category: Dehalogenase]]		[[Category: Dehalogenase]]
	[[Category: Ferredoxin fold]]		[[Category: Ferredoxin fold]]
	[[Category: Lyase]]		[[Category: Lyase]]

OCA at 08:58, 13 March 2013

OCA — Wed, 13 Mar 2013 08:58:56 GMT

←Older revision		Revision as of 08:58, 13 March 2013
Line 1:		Line 1:
-	[[Image:3zo7.jpg\|left\|200px]]
-
	{{STRUCTURE_3zo7\| PDB=3zo7 \| SCENE= }}		{{STRUCTURE_3zo7\| PDB=3zo7 \| SCENE= }}
-
	===Crystal structure of ClcFE27A with substrate===		===Crystal structure of ClcFE27A with substrate===
-		+	{{ABSTRACT_PUBMED_23421784}}

	==About this Structure==		==About this Structure==

OCA at 14:21, 6 March 2013

OCA — Wed, 06 Mar 2013 14:21:35 GMT

←Older revision		Revision as of 14:21, 6 March 2013
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	[[Image:3zo7.jpg\|left\|200px]]

-	~~The entry~~ 3zo7 ~~is ON HOLD~~	+	{{STRUCTURE_3zo7\| PDB=3zo7 \| SCENE= }}

-	~~Authors: Roth, C., Groening, J.A.D., Kaschabek, S.R., Schloemann, M., Straeter, N.~~	+	===Crystal structure of ClcFE27A with substrate===

-	~~Description: Crystal~~ structure ~~of ClcFE27A~~ with ~~substrate~~	+
		+	==About this Structure==
		+	[[3zo7]] is a 10 chain structure with sequence from [http://en.wikipedia.org/wiki/Rhodococcus_opacus Rhodococcus opacus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZO7 OCA].
		+	[[Category: Rhodococcus opacus]]
		+	[[Category: Groening, J A.D.]]
		+	[[Category: Kaschabek, S R.]]
		+	[[Category: Roth, C.]]
		+	[[Category: Schloemann, M.]]
		+	[[Category: Straeter, N.]]
		+	[[Category: Chlorocatechol pathway]]
		+	[[Category: Dehalogenase]]
		+	[[Category: Ferredoxin fold]]
		+	[[Category: Lyase]]

OCA: Protected "3zo7" [edit=sysop:move=sysop]

OCA — Wed, 27 Feb 2013 14:07:40 GMT

Protected "3zo7" [edit=sysop:move=sysop]

←Older revision

Revision as of 14:07, 27 February 2013

OCA: New page: '''Unreleased structure''' The entry 3zo7 is ON HOLD Authors: Roth, C., Groening, J.A.D., Kaschabek, S.R., Schloemann, M., Straeter, N. Description: Crystal structure of ClcFE27A with ...

OCA — Wed, 27 Feb 2013 14:07:39 GMT

New page: '''Unreleased structure''' The entry 3zo7 is ON HOLD Authors: Roth, C., Groening, J.A.D., Kaschabek, S.R., Schloemann, M., Straeter, N. Description: Crystal structure of ClcFE27A with ...

New page

'''Unreleased structure'''

The entry 3zo7 is ON HOLD

Authors: Roth, C., Groening, J.A.D., Kaschabek, S.R., Schloemann, M., Straeter, N.

Description: Crystal structure of ClcFE27A with substrate