3zof - Revision history

OCA at 11:08, 20 December 2023

OCA — Wed, 20 Dec 2023 11:08:16 GMT

←Older revision		Revision as of 11:08, 20 December 2023
Line 3:		Line 3:
	<StructureSection load='3zof' size='340' side='right'caption='[[3zof]], [[Resolution\|resolution]] 2.15Å' scene=''>		<StructureSection load='3zof' size='340' side='right'caption='[[3zof]], [[Resolution\|resolution]] 2.15Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3zof]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Thet2 Thet2~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZOF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3ZOF FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3zof]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus_HB27 Thermus thermophilus HB27]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZOF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3ZOF FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=HQE:BENZENE~~-1,~~4-DIOL'>HQE</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.15Å</td></tr>
-	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"><~~div style~~='~~overflow~~: ~~auto; max-height: 3em;~~'>~~[[3zoc\|3zoc]]~~, ~~[[3zod\|3zod]]~~, ~~[[3zoe\|3zoe]]~~</~~div~~></td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=HQE:BENZENE-1,4-DIOL'>HQE</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3zof FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zof OCA], [https://pdbe.org/3zof PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3zof RCSB], [https://www.ebi.ac.uk/pdbsum/3zof PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3zof ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3zof FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zof OCA], [https://pdbe.org/3zof PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3zof RCSB], [https://www.ebi.ac.uk/pdbsum/3zof PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3zof ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/Q72HI0_THET2 Q72HI0_THET2]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 22:		Line 24:
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Thet2~~]]	+	[[Category: Thermus thermophilus HB27]]
-	[[Category: Faber, K]]	+	[[Category: Faber K]]
-	[[Category: Gruber~~, C C~~]]	+	[[Category: Gruber CC]]
-	[[Category: Gruber, K]]	+	[[Category: Gruber K]]
-	[[Category: Pavkov-Keller, T]]	+	[[Category: Pavkov-Keller T]]
-	[[Category: Schwab, H]]	+	[[Category: Schwab H]]
-	[[Category: Schwamberger, O]]	+	[[Category: Schwamberger O]]
-	[[Category: Steiner, K]]	+	[[Category: Steiner K]]
-	[[Category: Steinkellner, G]]	+	[[Category: Steinkellner G]]
-	[[Category: Winkler, C]]	+	[[Category: Winkler C]]
-	~~[[Category: Fmn-binding protein~~]]	+

OCA at 07:05, 18 August 2022

OCA — Thu, 18 Aug 2022 07:05:22 GMT

←Older revision		Revision as of 07:05, 18 August 2022
Line 1:		Line 1:

	==Crystal structure of FMN-binding protein (YP_005476) from Thermus thermophilus with bound benzene-1,4-diol==		==Crystal structure of FMN-binding protein (YP_005476) from Thermus thermophilus with bound benzene-1,4-diol==
-	<StructureSection load='3zof' size='340' side='right' caption='[[3zof]], [[Resolution\|resolution]] 2.15Å' scene=''>	+	<StructureSection load='3zof' size='340' side='right'caption='[[3zof]], [[Resolution\|resolution]] 2.15Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3zof]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Thet2 Thet2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZOF OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3ZOF FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3zof]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Thet2 Thet2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZOF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3ZOF FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=HQE:BENZENE-1,4-DIOL'>HQE</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=HQE:BENZENE-1,4-DIOL'>HQE</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3zoc\|3zoc]], [[3zod\|3zod]], [[3zoe\|3zoe]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3zoc\|3zoc]], [[3zod\|3zod]], [[3zoe\|3zoe]]</div></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3zof FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zof OCA], [~~http~~://pdbe.org/3zof PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3zof RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3zof PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3zof ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3zof FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zof OCA], [https://pdbe.org/3zof PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3zof RCSB], [https://www.ebi.ac.uk/pdbsum/3zof PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3zof ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Thet2]]		[[Category: Thet2]]
	[[Category: Faber, K]]		[[Category: Faber, K]]

OCA at 16:15, 27 February 2019

OCA — Wed, 27 Feb 2019 16:15:01 GMT

←Older revision		Revision as of 16:15, 27 February 2019
Line 3:		Line 3:
	<StructureSection load='3zof' size='340' side='right' caption='[[3zof]], [[Resolution\|resolution]] 2.15Å' scene=''>		<StructureSection load='3zof' size='340' side='right' caption='[[3zof]], [[Resolution\|resolution]] 2.15Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3zof]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZOF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ZOF FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3zof]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Thet2 Thet2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZOF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ZOF FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=HQE:BENZENE-1,4-DIOL'>HQE</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=HQE:BENZENE-1,4-DIOL'>HQE</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3zoc\|3zoc]], [[3zod\|3zod]], [[3zoe\|3zoe]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3zoc\|3zoc]], [[3zod\|3zod]], [[3zoe\|3zoe]]</td></tr>
Line 21:		Line 21:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Thet2]]
	[[Category: Faber, K]]		[[Category: Faber, K]]
	[[Category: Gruber, C C]]		[[Category: Gruber, C C]]

OCA at 14:09, 11 August 2016

OCA — Thu, 11 Aug 2016 14:09:06 GMT

←Older revision		Revision as of 14:09, 11 August 2016
Line 1:		Line 1:
		+
	==Crystal structure of FMN-binding protein (YP_005476) from Thermus thermophilus with bound benzene-1,4-diol==		==Crystal structure of FMN-binding protein (YP_005476) from Thermus thermophilus with bound benzene-1,4-diol==
	<StructureSection load='3zof' size='340' side='right' caption='[[3zof]], [[Resolution\|resolution]] 2.15Å' scene=''>		<StructureSection load='3zof' size='340' side='right' caption='[[3zof]], [[Resolution\|resolution]] 2.15Å' scene=''>
Line 5:		Line 6:
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=HQE:BENZENE-1,4-DIOL'>HQE</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=HQE:BENZENE-1,4-DIOL'>HQE</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3zoc\|3zoc]], [[3zod\|3zod]], [[3zoe\|3zoe]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3zoc\|3zoc]], [[3zod\|3zod]], [[3zoe\|3zoe]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3zof FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zof OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3zof RCSB], [http://www.ebi.ac.uk/pdbsum/3zof PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3zof FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zof OCA], [http://pdbe.org/3zof PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3zof RCSB], [http://www.ebi.ac.uk/pdbsum/3zof PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3zof ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 15:		Line 16:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3zof" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 09:04, 4 January 2015

OCA — Sun, 04 Jan 2015 09:04:14 GMT

←Older revision		Revision as of 09:04, 4 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3zof]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZOF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ZOF FirstGlance]. <br>		<table><tr><td colspan='2'>[[3zof]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZOF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ZOF FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=HQE:BENZENE-1,4-DIOL'>HQE</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=HQE:BENZENE-1,4-DIOL'>HQE</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3zoc\|3zoc]], [[3zod\|3zod]], [[3zoe\|3zoe]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3zoc\|3zoc]], [[3zod\|3zod]], [[3zoe\|3zoe]]</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3zof FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zof OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3zof RCSB], [http://www.ebi.ac.uk/pdbsum/3zof PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3zof FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zof OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3zof RCSB], [http://www.ebi.ac.uk/pdbsum/3zof PDBsum]</span></td></tr>
-	<table>	+	</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 19:		Line 19:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Faber, K.]]	+	[[Category: Faber, K]]
-	[[Category: Gruber, C C.]]	+	[[Category: Gruber, C C]]
-	[[Category: Gruber, K.]]	+	[[Category: Gruber, K]]
-	[[Category: Pavkov-Keller, T.]]	+	[[Category: Pavkov-Keller, T]]
-	[[Category: Schwab, H.]]	+	[[Category: Schwab, H]]
-	[[Category: Schwamberger, O.]]	+	[[Category: Schwamberger, O]]
-	[[Category: Steiner, K.]]	+	[[Category: Steiner, K]]
-	[[Category: Steinkellner, G.]]	+	[[Category: Steinkellner, G]]
-	[[Category: Winkler, C.]]	+	[[Category: Winkler, C]]
	[[Category: Fmn-binding protein]]		[[Category: Fmn-binding protein]]

OCA at 06:08, 2 July 2014

OCA — Wed, 02 Jul 2014 06:08:03 GMT

←Older revision		Revision as of 06:08, 2 July 2014
Line 2:		Line 2:
	<StructureSection load='3zof' size='340' side='right' caption='[[3zof]], [[Resolution\|resolution]] 2.15Å' scene=''>		<StructureSection load='3zof' size='340' side='right' caption='[[3zof]], [[Resolution\|resolution]] 2.15Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3zof]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZOF OCA]. <br>	+	<table><tr><td colspan='2'>[[3zof]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZOF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ZOF FirstGlance]. <br>
	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=HQE:BENZENE-1,4-DIOL'>HQE</scene><br>		</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=HQE:BENZENE-1,4-DIOL'>HQE</scene><br>
	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3zoc\|3zoc]], [[3zod\|3zod]], [[3zoe\|3zoe]]</td></tr>		<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3zoc\|3zoc]], [[3zod\|3zod]], [[3zoe\|3zoe]]</td></tr>
-	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span></td></tr>
	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3zof FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zof OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3zof RCSB], [http://www.ebi.ac.uk/pdbsum/3zof PDBsum]</span></td></tr>		<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3zof FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zof OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3zof RCSB], [http://www.ebi.ac.uk/pdbsum/3zof PDBsum]</span></td></tr>
	<table>		<table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The exploitation of catalytic promiscuity and the application of de novo design have recently opened the access to novel, non-natural enzymatic activities. Here we describe a structural bioinformatic method for predicting catalytic activities of enzymes based on three-dimensional constellations of functional groups in active sites ('catalophores'). As a proof-of-concept we identify two enzymes with predicted promiscuous ene-reductase activity (reduction of activated C-C double bonds) and compare them with known ene-reductases, that is, members of the Old Yellow Enzyme family. Despite completely different amino acid sequences, overall structures and protein folds, high-resolution crystal structures reveal equivalent binding modes of typical Old Yellow Enzyme substrates and ligands. Biochemical and biocatalytic data show that the two enzymes indeed possess ene-reductase activity and reveal an inverted stereopreference compared with Old Yellow Enzymes for some substrates. This method could thus be a tool for the identification of viable starting points for the development and engineering of novel biocatalysts.
		+
		+	Identification of promiscuous ene-reductase activity by mining structural databases using active site constellations.,Steinkellner G, Gruber CC, Pavkov-Keller T, Binter A, Steiner K, Winkler C, Lyskowski A, Schwamberger O, Oberer M, Schwab H, Faber K, Macheroux P, Gruber K Nat Commun. 2014 Jun 23;5:4150. doi: 10.1038/ncomms5150. PMID:24954722<ref>PMID:24954722</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>

OCA at 07:22, 14 May 2014

OCA — Wed, 14 May 2014 07:22:32 GMT

←Older revision		Revision as of 07:22, 14 May 2014
Line 1:		Line 1:
-	'''~~Unreleased structure~~'''	+	==Crystal structure of FMN-binding protein (YP_005476) from Thermus thermophilus with bound benzene-1,4-diol==
-		+	<StructureSection load='3zof' size='340' side='right' caption='[[3zof]], [[Resolution\|resolution]] 2.15Å' scene=''>
-	~~The entry~~ 3zof is ~~ON HOLD until Paper Publication~~	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[3zof]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZOF OCA]. <br>
-	~~Authors~~: ~~Pavkov~~-~~Keller~~, T., ~~Steinkellner~~, G., ~~Gruber~~, C.C., ~~Steiner~~, K.~~, Winkler~~, C., ~~Schwamberger, O~~., Schwab, H., ~~Faber~~, K., ~~Gruber~~, K.	+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=HQE:BENZENE-1,4-DIOL'>HQE</scene><br>
-		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3zoc\|3zoc]], [[3zod\|3zod]], [[3zoe\|3zoe]]</td></tr>
-	~~Description~~: ~~Crystal structure of FMN~~-binding protein ~~(YP_005476) from Thermus thermophilus with bound benzene-1,4-diol~~	+	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span></td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3zof FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zof OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3zof RCSB], [http://www.ebi.ac.uk/pdbsum/3zof PDBsum]</span></td></tr>
		+	<table>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Faber, K.]]
		+	[[Category: Gruber, C C.]]
		+	[[Category: Gruber, K.]]
		+	[[Category: Pavkov-Keller, T.]]
		+	[[Category: Schwab, H.]]
		+	[[Category: Schwamberger, O.]]
		+	[[Category: Steiner, K.]]
		+	[[Category: Steinkellner, G.]]
		+	[[Category: Winkler, C.]]
		+	[[Category: Fmn-binding protein]]

OCA at 10:43, 19 June 2013

OCA — Wed, 19 Jun 2013 10:43:36 GMT

←Older revision		Revision as of 10:43, 19 June 2013
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	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 3zof is ON HOLD	+	The entry 3zof is ON HOLD until Paper Publication

	Authors: Pavkov-Keller, T., Steinkellner, G., Gruber, C.C., Steiner, K., Winkler, C., Schwamberger, O., Schwab, H., Faber, K., Gruber, K.		Authors: Pavkov-Keller, T., Steinkellner, G., Gruber, C.C., Steiner, K., Winkler, C., Schwamberger, O., Schwab, H., Faber, K., Gruber, K.

	Description: Crystal structure of FMN-binding protein (YP_005476) from Thermus thermophilus with bound benzene-1,4-diol		Description: Crystal structure of FMN-binding protein (YP_005476) from Thermus thermophilus with bound benzene-1,4-diol

OCA: Protected "3zof" [edit=sysop:move=sysop]

OCA — Wed, 27 Feb 2013 14:07:56 GMT

Protected "3zof" [edit=sysop:move=sysop]

←Older revision

Revision as of 14:07, 27 February 2013

OCA: New page: '''Unreleased structure''' The entry 3zof is ON HOLD Authors: Pavkov-Keller, T., Steinkellner, G., Gruber, C.C., Steiner, K., Winkler, C., Schwamberger, O., Schwab, H., Faber, K., Grube...

OCA — Wed, 27 Feb 2013 14:07:55 GMT

New page: '''Unreleased structure''' The entry 3zof is ON HOLD Authors: Pavkov-Keller, T., Steinkellner, G., Gruber, C.C., Steiner, K., Winkler, C., Schwamberger, O., Schwab, H., Faber, K., Grube...

New page

'''Unreleased structure'''

The entry 3zof is ON HOLD

Authors: Pavkov-Keller, T., Steinkellner, G., Gruber, C.C., Steiner, K., Winkler, C., Schwamberger, O., Schwab, H., Faber, K., Gruber, K.

Description: Crystal structure of FMN-binding protein (YP_005476) from Thermus thermophilus with bound benzene-1,4-diol