3zp4 - Revision history

OCA at 09:09, 15 November 2023

OCA — Wed, 15 Nov 2023 09:09:40 GMT

←Older revision		Revision as of 09:09, 15 November 2023
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	<StructureSection load='3zp4' size='340' side='right'caption='[[3zp4]], [[Resolution\|resolution]] 1.80Å' scene=''>		<StructureSection load='3zp4' size='340' side='right'caption='[[3zp4]], [[Resolution\|resolution]] 1.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3zp4]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/~~"vibrio_subtilis"_ehrenberg_1835 "vibrio~~ subtilis~~" ehrenberg 1835~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZP4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3ZP4 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3zp4]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZP4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3ZP4 FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=TSA:8~~-~~HYDROXY-2-OXA-BICYCLO~~[3.~~3.1]NON-6-ENE-3,5-DICARBOXYLIC+ACID'>TSA</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.798Å</td></tr>
-	<tr id='~~NonStdRes~~'><td class="sblockLbl"><b>[[~~Non-Standard_Residue~~\|~~NonStd Res~~:]]</b></td><td class="sblockDat"><scene name='pdbligand=CIR:CITRULLINE'>CIR</scene><~~/td></tr>~~	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CIR:CITRULLINE'>CIR</scene>, <scene name='pdbligand=TSA:8-HYDROXY-2-OXA-BICYCLO[3.3.1]NON-6-ENE-3,5-DICARBOXYLIC+ACID'>TSA</scene></td></tr>
-	~~<tr id~~='~~related'><td class~~=~~"sblockLbl"><b>~~[~~[Related_structure\|Related:~~]~~]</b></td><td class="sblockDat"><div style='overflow: auto; max~~-~~height: 3em;~~'>~~[[3zo8\|3zo8]], [[3zop\|3zop]], [[3zp8\|3zp8]]~~</~~div~~></td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3zp4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zp4 OCA], [https://pdbe.org/3zp4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3zp4 RCSB], [https://www.ebi.ac.uk/pdbsum/3zp4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3zp4 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3zp4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zp4 OCA], [https://pdbe.org/3zp4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3zp4 RCSB], [https://www.ebi.ac.uk/pdbsum/3zp4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3zp4 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/AROH_BACSU AROH_BACSU]] Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis.<ref>PMID:2105742</ref>	+	[https://www.uniprot.org/uniprot/AROH_BACSU AROH_BACSU] Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis.<ref>PMID:2105742</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Vibrio~~ subtilis ~~ehrenberg 1835~~]]	+	[[Category: Bacillus subtilis]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Burschowsky, D]]	+	[[Category: Burschowsky D]]
-	[[Category: Hilvert, D]]	+	[[Category: Hilvert D]]
-	[[Category: Kast, P]]	+	[[Category: Kast P]]
-	[[Category: Kienhofer, A]]	+	[[Category: Kienhofer A]]
-	[[Category: Krengel, U]]	+	[[Category: Krengel U]]
-	[[Category: Okvist, M]]	+	[[Category: Okvist M]]
-	[[Category: VanEerde, A]]	+	[[Category: VanEerde A]]
-	~~[[Category: Isomerase]]~~	+
-	~~[[Category: Non-proteinogenic amino acid]]~~	+
-	~~[[Category: Pseudo-alpha beta-barrel]]~~	+
-	~~[[Category: Semi-synthetic]]~~	+
-	~~[[Category: Transition state analog~~]]	+

OCA at 07:07, 18 August 2022

OCA — Thu, 18 Aug 2022 07:07:06 GMT

←Older revision		Revision as of 07:07, 18 August 2022
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	==Arg90Cit chorismate mutase of Bacillus subtilis in complex with a transition state analog==		==Arg90Cit chorismate mutase of Bacillus subtilis in complex with a transition state analog==
-	<StructureSection load='3zp4' size='340' side='right' caption='[[3zp4]], [[Resolution\|resolution]] 1.80Å' scene=''>	+	<StructureSection load='3zp4' size='340' side='right'caption='[[3zp4]], [[Resolution\|resolution]] 1.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3zp4]] is a 6 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/"vibrio_subtilis"_ehrenberg_1835 "vibrio subtilis" ehrenberg 1835]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZP4 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3ZP4 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3zp4]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/"vibrio_subtilis"_ehrenberg_1835 "vibrio subtilis" ehrenberg 1835]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZP4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3ZP4 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=TSA:8-HYDROXY-2-OXA-BICYCLO[3.3.1]NON-6-ENE-3,5-DICARBOXYLIC+ACID'>TSA</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=TSA:8-HYDROXY-2-OXA-BICYCLO[3.3.1]NON-6-ENE-3,5-DICARBOXYLIC+ACID'>TSA</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CIR:CITRULLINE'>CIR</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CIR:CITRULLINE'>CIR</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3zo8\|3zo8]], [[3zop\|3zop]], [[3zp8\|3zp8]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3zo8\|3zo8]], [[3zop\|3zop]], [[3zp8\|3zp8]]</div></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3zp4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zp4 OCA], [~~http~~://pdbe.org/3zp4 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3zp4 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3zp4 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3zp4 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3zp4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zp4 OCA], [https://pdbe.org/3zp4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3zp4 RCSB], [https://www.ebi.ac.uk/pdbsum/3zp4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3zp4 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/AROH_BACSU AROH_BACSU]] Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis.<ref>PMID:2105742</ref>	+	[[https://www.uniprot.org/uniprot/AROH_BACSU AROH_BACSU]] Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis.<ref>PMID:2105742</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	</div>		</div>
	<div class="pdbe-citations 3zp4" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 3zp4" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[3D structures of chorismate mutase\|3D structures of chorismate mutase]]
	== References ==		== References ==
	<references/>		<references/>
Line 25:		Line 28:
	</StructureSection>		</StructureSection>
	[[Category: Vibrio subtilis ehrenberg 1835]]		[[Category: Vibrio subtilis ehrenberg 1835]]
		+	[[Category: Large Structures]]
	[[Category: Burschowsky, D]]		[[Category: Burschowsky, D]]
	[[Category: Hilvert, D]]		[[Category: Hilvert, D]]

OCA at 16:20, 27 February 2019

OCA — Wed, 27 Feb 2019 16:20:23 GMT

←Older revision		Revision as of 16:20, 27 February 2019
Line 3:		Line 3:
	<StructureSection load='3zp4' size='340' side='right' caption='[[3zp4]], [[Resolution\|resolution]] 1.80Å' scene=''>		<StructureSection load='3zp4' size='340' side='right' caption='[[3zp4]], [[Resolution\|resolution]] 1.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3zp4]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/"~~bacillus_globigii~~"~~_migula_1900~~ "~~bacillus globigii~~" ~~migula 1900~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZP4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ZP4 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3zp4]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/"vibrio_subtilis"_ehrenberg_1835 "vibrio subtilis" ehrenberg 1835]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZP4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ZP4 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=TSA:8-HYDROXY-2-OXA-BICYCLO[3.3.1]NON-6-ENE-3,5-DICARBOXYLIC+ACID'>TSA</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=TSA:8-HYDROXY-2-OXA-BICYCLO[3.3.1]NON-6-ENE-3,5-DICARBOXYLIC+ACID'>TSA</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CIR:CITRULLINE'>CIR</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CIR:CITRULLINE'>CIR</scene></td></tr>
Line 24:		Line 24:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Bacillus globigii migula 1900~~]]	+	[[Category: Vibrio subtilis ehrenberg 1835]]
	[[Category: Burschowsky, D]]		[[Category: Burschowsky, D]]
	[[Category: Hilvert, D]]		[[Category: Hilvert, D]]

OCA at 13:27, 4 August 2016

OCA — Thu, 04 Aug 2016 13:27:29 GMT

←Older revision		Revision as of 13:27, 4 August 2016
Line 1:		Line 1:
		+
	==Arg90Cit chorismate mutase of Bacillus subtilis in complex with a transition state analog==		==Arg90Cit chorismate mutase of Bacillus subtilis in complex with a transition state analog==
	<StructureSection load='3zp4' size='340' side='right' caption='[[3zp4]], [[Resolution\|resolution]] 1.80Å' scene=''>		<StructureSection load='3zp4' size='340' side='right' caption='[[3zp4]], [[Resolution\|resolution]] 1.80Å' scene=''>
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	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CIR:CITRULLINE'>CIR</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CIR:CITRULLINE'>CIR</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3zo8\|3zo8]], [[3zop\|3zop]], [[3zp8\|3zp8]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3zo8\|3zo8]], [[3zop\|3zop]], [[3zp8\|3zp8]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3zp4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zp4 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3zp4 RCSB], [http://www.ebi.ac.uk/pdbsum/3zp4 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3zp4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zp4 OCA], [http://pdbe.org/3zp4 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3zp4 RCSB], [http://www.ebi.ac.uk/pdbsum/3zp4 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3zp4 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
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	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3zp4" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 11:20, 24 December 2014

OCA — Wed, 24 Dec 2014 11:20:12 GMT

←Older revision		Revision as of 11:20, 24 December 2014
Line 8:		Line 8:
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3zp4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zp4 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3zp4 RCSB], [http://www.ebi.ac.uk/pdbsum/3zp4 PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3zp4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zp4 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3zp4 RCSB], [http://www.ebi.ac.uk/pdbsum/3zp4 PDBsum]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/AROH_BACSU AROH_BACSU]] Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis.<ref>PMID:2105742</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==

OCA at 12:00, 10 December 2014

OCA — Wed, 10 Dec 2014 12:00:50 GMT

←Older revision		Revision as of 12:00, 10 December 2014
Line 8:		Line 8:
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3zp4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zp4 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3zp4 RCSB], [http://www.ebi.ac.uk/pdbsum/3zp4 PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3zp4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zp4 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3zp4 RCSB], [http://www.ebi.ac.uk/pdbsum/3zp4 PDBsum]</span></td></tr>
	</table>		</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	For more than half a century, transition state theory has provided a useful framework for understanding the origins of enzyme catalysis. As proposed by Pauling, enzymes accelerate chemical reactions by binding transition states tighter than substrates, thereby lowering the activation energy compared with that of the corresponding uncatalyzed process. This paradigm has been challenged for chorismate mutase (CM), a well-characterized metabolic enzyme that catalyzes the rearrangement of chorismate to prephenate. Calculations have predicted the decisive factor in CM catalysis to be ground state destabilization rather than transition state stabilization. Using X-ray crystallography, we show, in contrast, that a sluggish variant of Bacillus subtilis CM, in which a cationic active-site arginine was replaced by a neutral citrulline, is a poor catalyst even though it effectively preorganizes chorismate for the reaction. A series of high-resolution molecular snapshots of the reaction coordinate, including the apo enzyme, and complexes with substrate, transition state analog and product, demonstrate that an active site, which is only complementary in shape to a reactive substrate conformer, is insufficient for effective catalysis. Instead, as with other enzymes, electrostatic stabilization of the CM transition state appears to be crucial for achieving high reaction rates.
		+
		+	Electrostatic transition state stabilization rather than reactant destabilization provides the chemical basis for efficient chorismate mutase catalysis.,Burschowsky D, van Eerde A, Okvist M, Kienhofer A, Kast P, Hilvert D, Krengel U Proc Natl Acad Sci U S A. 2014 Nov 24. pii: 201408512. PMID:25422475<ref>PMID:25422475</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>

OCA at 06:03, 26 November 2014

OCA — Wed, 26 Nov 2014 06:03:14 GMT

←Older revision		Revision as of 06:03, 26 November 2014
Line 1:		Line 1:
-	~~{{STRUCTURE_3zp4\| PDB=3zp4 \| SCENE= }}~~	+	==Arg90Cit chorismate mutase of Bacillus subtilis in complex with a transition state analog==
-	===Arg90Cit chorismate mutase of Bacillus subtilis in complex with a transition state analog===	+	<StructureSection load='3zp4' size='340' side='right' caption='[[3zp4]], [[Resolution\|resolution]] 1.80Å' scene=''>
-		+	== Structural highlights ==
-	==~~Function~~==	+	<table><tr><td colspan='2'>[[3zp4]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_globigii"_migula_1900 "bacillus globigii" migula 1900]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZP4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ZP4 FirstGlance]. <br>
-	[[~~http://www.uniprot.org/uniprot/AROH_BACSU AROH_BACSU~~]] ~~Catalyzes the Claisen rearrangement of chorismate to prephenate~~. ~~Probably involved in the aromatic amino acid biosynthesis.<ref~~>~~PMID:2105742</ref>~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=TSA:8-HYDROXY-2-OXA-BICYCLO[3.3.1]NON-6-ENE-3,5-DICARBOXYLIC+ACID'>TSA</scene></td></tr>
-		+	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CIR:CITRULLINE'>CIR</scene></td></tr>
-	==~~About this Structure~~==	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3zo8\|3zo8]], [[3zop\|3zop]], [[3zp8\|3zp8]]</td></tr>
-	[[3zp4]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZP4 OCA].	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3zp4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zp4 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3zp4 RCSB], [http://www.ebi.ac.uk/pdbsum/3zp4 PDBsum]</span></td></tr>
-		+	</table>
-	==~~Reference~~==	+	__TOC__
-	<~~references group~~="~~xtra~~"/><~~references~~/>	+	</StructureSection>
-	[[Category: Burschowsky, D.]]	+	[[Category: Bacillus globigii migula 1900]]
-	[[Category: Hilvert, D.]]	+	[[Category: Burschowsky, D]]
-	[[Category: Kast, P.]]	+	[[Category: Hilvert, D]]
-	[[Category: Kienhofer, A.]]	+	[[Category: Kast, P]]
-	[[Category: Krengel, U.]]	+	[[Category: Kienhofer, A]]
-	[[Category: Okvist, M.]]	+	[[Category: Krengel, U]]
-	[[Category: VanEerde, A.]]	+	[[Category: Okvist, M]]
		+	[[Category: VanEerde, A]]
	[[Category: Isomerase]]		[[Category: Isomerase]]
	[[Category: Non-proteinogenic amino acid]]		[[Category: Non-proteinogenic amino acid]]

OCA at 09:57, 16 April 2014

OCA — Wed, 16 Apr 2014 09:57:49 GMT

←Older revision		Revision as of 09:57, 16 April 2014
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	{{STRUCTURE_3zp4\| PDB=3zp4 \| SCENE= }}
		+	===Arg90Cit chorismate mutase of Bacillus subtilis in complex with a transition state analog===

-	~~The entry 3zp4 is ON HOLD~~ ~~until Paper Publication~~	+	==Function==
		+	[[http://www.uniprot.org/uniprot/AROH_BACSU AROH_BACSU]] Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis.<ref>PMID:2105742</ref>

-	~~Authors~~: ~~Burschowsky, D., vanEerde, A., Okvist, M., Kienhofer, A~~.~~, Kast, P~~.~~, Hilvert, D~~.~~, Krengel, U~~.	+	==About this Structure==
		+	[[3zp4]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZP4 OCA].

-	~~Description~~: ~~Arg90Cit chorismate mutase of Bacillus subtilis in complex with a transition~~ state analog	+	==Reference==
		+	<references group="xtra"/><references/>
		+	[[Category: Burschowsky, D.]]
		+	[[Category: Hilvert, D.]]
		+	[[Category: Kast, P.]]
		+	[[Category: Kienhofer, A.]]
		+	[[Category: Krengel, U.]]
		+	[[Category: Okvist, M.]]
		+	[[Category: VanEerde, A.]]
		+	[[Category: Isomerase]]
		+	[[Category: Non-proteinogenic amino acid]]
		+	[[Category: Pseudo-alpha beta-barrel]]
		+	[[Category: Semi-synthetic]]
		+	[[Category: Transition state analog]]

OCA at 09:41, 13 March 2013

OCA — Wed, 13 Mar 2013 09:41:23 GMT

←Older revision		Revision as of 09:41, 13 March 2013
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 3zp4 is ON HOLD	+	The entry 3zp4 is ON HOLD until Paper Publication

	Authors: Burschowsky, D., vanEerde, A., Okvist, M., Kienhofer, A., Kast, P., Hilvert, D., Krengel, U.		Authors: Burschowsky, D., vanEerde, A., Okvist, M., Kienhofer, A., Kast, P., Hilvert, D., Krengel, U.

	Description: Arg90Cit chorismate mutase of Bacillus subtilis in complex with a transition state analog		Description: Arg90Cit chorismate mutase of Bacillus subtilis in complex with a transition state analog

OCA: Protected "3zp4" [edit=sysop:move=sysop]

OCA — Wed, 06 Mar 2013 13:36:03 GMT

Protected "3zp4" [edit=sysop:move=sysop]

←Older revision

Revision as of 13:36, 6 March 2013