3zpp - Revision history

OCA at 10:41, 9 May 2024

OCA — Thu, 09 May 2024 10:41:57 GMT

←Older revision		Revision as of 10:41, 9 May 2024
Line 3:		Line 3:
	<StructureSection load='3zpp' size='340' side='right'caption='[[3zpp]], [[Resolution\|resolution]] 2.28Å' scene=''>		<StructureSection load='3zpp' size='340' side='right'caption='[[3zpp]], [[Resolution\|resolution]] 2.28Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3zpp]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Strpn Strpn~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZPP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3ZPP FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3zpp]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptococcus_pneumoniae_TIGR4 Streptococcus pneumoniae TIGR4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZPP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3ZPP FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.28Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3zpp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zpp OCA], [https://pdbe.org/3zpp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3zpp RCSB], [https://www.ebi.ac.uk/pdbsum/3zpp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3zpp ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3zpp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zpp OCA], [https://pdbe.org/3zpp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3zpp RCSB], [https://www.ebi.ac.uk/pdbsum/3zpp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3zpp ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/A0A0H2URN9_STRPN A0A0H2URN9_STRPN]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 21:		Line 24:
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Strpn~~]]	+	[[Category: Streptococcus pneumoniae TIGR4]]
-	[[Category: Boraston~~, A B~~]]	+	[[Category: Boraston AB]]
-	[[Category: Suits~~, M D.L]]~~	+	[[Category: L Suits MD]]
-	~~[[Category: Cell adhesion]]~~	+
-	~~[[Category: Mscramm]]~~	+
-	~~[[Category: Pfba]]~~	+
-	~~[[Category: Sp1833]]~~	+
-	~~[[Category: Surface adhesin~~]]	+

OCA at 07:08, 18 August 2022

OCA — Thu, 18 Aug 2022 07:08:14 GMT

←Older revision		Revision as of 07:08, 18 August 2022
Line 1:		Line 1:

	==Structure of the Streptococcus pneumoniae surface protein and adhesin PfbA==		==Structure of the Streptococcus pneumoniae surface protein and adhesin PfbA==
-	<StructureSection load='3zpp' size='340' side='right' caption='[[3zpp]], [[Resolution\|resolution]] 2.28Å' scene=''>	+	<StructureSection load='3zpp' size='340' side='right'caption='[[3zpp]], [[Resolution\|resolution]] 2.28Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3zpp]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Strpn Strpn]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZPP OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3ZPP FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3zpp]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Strpn Strpn]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZPP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3ZPP FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3zpp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zpp OCA], [~~http~~://pdbe.org/3zpp PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3zpp RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3zpp PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3zpp ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3zpp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zpp OCA], [https://pdbe.org/3zpp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3zpp RCSB], [https://www.ebi.ac.uk/pdbsum/3zpp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3zpp ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 20:		Line 20:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Strpn]]		[[Category: Strpn]]
	[[Category: Boraston, A B]]		[[Category: Boraston, A B]]

OCA at 03:56, 5 August 2016

OCA — Fri, 05 Aug 2016 03:56:18 GMT

←Older revision		Revision as of 03:56, 5 August 2016
Line 1:		Line 1:
		+
	==Structure of the Streptococcus pneumoniae surface protein and adhesin PfbA==		==Structure of the Streptococcus pneumoniae surface protein and adhesin PfbA==
	<StructureSection load='3zpp' size='340' side='right' caption='[[3zpp]], [[Resolution\|resolution]] 2.28Å' scene=''>		<StructureSection load='3zpp' size='340' side='right' caption='[[3zpp]], [[Resolution\|resolution]] 2.28Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3zpp]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Streptococcus_pneumoniae_tigr4 Streptococcus pneumoniae tigr4~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZPP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ZPP FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3zpp]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Strpn Strpn]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZPP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ZPP FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3zpp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zpp OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3zpp RCSB], [http://www.ebi.ac.uk/pdbsum/3zpp PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3zpp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zpp OCA], [http://pdbe.org/3zpp PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3zpp RCSB], [http://www.ebi.ac.uk/pdbsum/3zpp PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3zpp ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 14:		Line 15:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3zpp" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Streptococcus pneumoniae tigr4~~]]	+	[[Category: Strpn]]
	[[Category: Boraston, A B]]		[[Category: Boraston, A B]]
	[[Category: Suits, M D.L]]		[[Category: Suits, M D.L]]

OCA at 08:46, 21 December 2014

OCA — Sun, 21 Dec 2014 08:46:32 GMT

←Older revision		Revision as of 08:46, 21 December 2014
Line 1:		Line 1:
-	~~{{STRUCTURE_3zpp\| PDB=3zpp \| SCENE= }}~~	+	==Structure of the Streptococcus pneumoniae surface protein and adhesin PfbA==
-	===Structure of the Streptococcus pneumoniae surface protein and adhesin PfbA===	+	<StructureSection load='3zpp' size='340' side='right' caption='[[3zpp]], [[Resolution\|resolution]] 2.28Å' scene=''>
-	~~{{ABSTRACT_PUBMED_23894284}}~~	+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[3zpp]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptococcus_pneumoniae_tigr4 Streptococcus pneumoniae tigr4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZPP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ZPP FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3zpp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zpp OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3zpp RCSB], [http://www.ebi.ac.uk/pdbsum/3zpp PDBsum]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	PfbA (plasmin- and fibronectin-binding protein A) is an extracellular Streptococcus pneumoniae cell-wall attached surface protein that binds to fibronectin, plasmin, and plasminogen. Here we present a structural analysis of the surface exposed domains of PfbA using a combined approach of X-ray crystallography and small-angle X-ray scattering (SAXS). The crystal structure of the PfbA core domain, here called PfbAbeta, determined to 2.28 A resolution revealed an elongated 12-stranded parallel beta-helix fold, which structure-based comparisons reveal is most similar to proteins with carbohydrate modifying activity. A notable feature of the PfbAbeta is an extensive cleft on one face of the protein with electrochemical and spatial features that are analogous to structurally similar carbohydrate-active enzymes utilizing this feature for substrate accommodation. Though this cleft displays a combination of basic amino acid residues and solvent exposed aromatic amino acids that are distinct features for recognition of carbohydrates, no obvious arrangement of amino acid side chains that would constitute catalytic machinery is evident. The pseudo-atomic SAXS model of a larger fragment of PfbA suggests that it has a relatively well-ordered structure with the N-terminal and core domains of PfbA adopting an extend organization and reveals a novel structural class of surface exposed pneumococcal matrix molecule adhesins.

-	~~==About this~~ Structure==	+	Structure of the Streptococcus pneumoniae Surface Protein and Adhesin PfbA.,Suits MD, Boraston AB PLoS One. 2013 Jul 22;8(7):e67190. doi: 10.1371/journal.pone.0067190. Print 2013. PMID:23894284<ref>PMID:23894284</ref>
-	~~[[3zpp]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptococcus_pneumoniae_tigr4~~ Streptococcus pneumoniae ~~tigr4]~~. ~~Full crystallographic information is available from [http~~:/~~/oca~~.~~weizmann~~.ac.il/~~oca-bin/ocashort?id=3ZPP OCA].~~	+

-	==~~Reference~~==	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	~~<ref group="xtra">PMID:023894284</ref>~~<references ~~group="xtra"~~/><~~references~~/>	+	</div>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
	[[Category: Streptococcus pneumoniae tigr4]]		[[Category: Streptococcus pneumoniae tigr4]]
-	[[Category: Boraston, A B.]]	+	[[Category: Boraston, A B]]
-	[[Category: Suits, M D.L.]]	+	[[Category: Suits, M D.L]]
	[[Category: Cell adhesion]]		[[Category: Cell adhesion]]
	[[Category: Mscramm]]		[[Category: Mscramm]]

OCA at 06:27, 14 August 2013

OCA — Wed, 14 Aug 2013 06:27:55 GMT

←Older revision		Revision as of 06:27, 14 August 2013
Line 1:		Line 1:
	{{STRUCTURE_3zpp\| PDB=3zpp \| SCENE= }}		{{STRUCTURE_3zpp\| PDB=3zpp \| SCENE= }}
	===Structure of the Streptococcus pneumoniae surface protein and adhesin PfbA===		===Structure of the Streptococcus pneumoniae surface protein and adhesin PfbA===
		+	{{ABSTRACT_PUBMED_23894284}}

	==About this Structure==		==About this Structure==
	[[3zpp]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptococcus_pneumoniae_tigr4 Streptococcus pneumoniae tigr4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZPP OCA].		[[3zpp]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptococcus_pneumoniae_tigr4 Streptococcus pneumoniae tigr4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZPP OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:023894284</ref><references group="xtra"/><references/>
	[[Category: Streptococcus pneumoniae tigr4]]		[[Category: Streptococcus pneumoniae tigr4]]
	[[Category: Boraston, A B.]]		[[Category: Boraston, A B.]]

OCA at 16:16, 19 June 2013

OCA — Wed, 19 Jun 2013 16:16:29 GMT

←Older revision		Revision as of 16:16, 19 June 2013
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	{{STRUCTURE_3zpp\| PDB=3zpp \| SCENE= }}
		+	===Structure of the Streptococcus pneumoniae surface protein and adhesin PfbA===

-	~~The entry~~ 3zpp is ~~ON HOLD~~	+	==About this Structure==
-		+	[[3zpp]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptococcus_pneumoniae_tigr4 Streptococcus pneumoniae tigr4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZPP OCA].
-	~~Authors~~: L Suits, M.D.~~, Boraston, A.B~~.	+	[[Category: Streptococcus pneumoniae tigr4]]
-		+	[[Category: Boraston, A B.]]
-	~~Description~~: ~~Structure of the Streptococcus pneumoniae surface protein and~~ adhesin ~~PfbA~~	+	[[Category: Suits, M D.L.]]
		+	[[Category: Cell adhesion]]
		+	[[Category: Mscramm]]
		+	[[Category: Pfba]]
		+	[[Category: Sp1833]]
		+	[[Category: Surface adhesin]]

OCA: Protected "3zpp" [edit=sysop:move=sysop]

OCA — Wed, 06 Mar 2013 13:36:35 GMT

Protected "3zpp" [edit=sysop:move=sysop]

←Older revision

Revision as of 13:36, 6 March 2013

OCA: New page: '''Unreleased structure''' The entry 3zpp is ON HOLD Authors: L Suits, M.D., Boraston, A.B. Description: Structure of the Streptococcus pneumoniae surface protein and adhesin PfbA

OCA — Wed, 06 Mar 2013 13:36:34 GMT

New page: '''Unreleased structure''' The entry 3zpp is ON HOLD Authors: L Suits, M.D., Boraston, A.B. Description: Structure of the Streptococcus pneumoniae surface protein and adhesin PfbA

New page

'''Unreleased structure'''

The entry 3zpp is ON HOLD

Authors: L Suits, M.D., Boraston, A.B.

Description: Structure of the Streptococcus pneumoniae surface protein and adhesin PfbA