3zpz - Revision history

OCA at 10:42, 9 May 2024

OCA — Thu, 09 May 2024 10:42:03 GMT

←Older revision		Revision as of 10:42, 9 May 2024
Line 3:		Line 3:
	<SX load='3zpz' size='340' side='right' viewer='molstar' caption='[[3zpz]], [[Resolution\|resolution]] 8.90Å' scene=''>		<SX load='3zpz' size='340' side='right' viewer='molstar' caption='[[3zpz]], [[Resolution\|resolution]] 8.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3zpz]] is a 21 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Ecobb Ecobb~~] and [https://en.wikipedia.org/wiki/~~Ecoli Ecoli~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZPZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3ZPZ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3zpz]] is a 21 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_BL21 Escherichia coli BL21] and [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZPZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3ZPZ FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>~~, ~~<scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution\|Resolution]] 8.9Å</td></tr>
-	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"><~~div style~~='~~overflow~~: ~~auto; max~~-~~height: 3em;~~'>~~[[3zq0\|3zq0]]~~, ~~[[3zq1\|3zq1]]~~</~~div~~></td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3zpz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zpz OCA], [https://pdbe.org/3zpz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3zpz RCSB], [https://www.ebi.ac.uk/pdbsum/3zpz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3zpz ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3zpz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zpz OCA], [https://pdbe.org/3zpz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3zpz RCSB], [https://www.ebi.ac.uk/pdbsum/3zpz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3zpz ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/CH60_ECOLI CH60_ECOLI]] Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.[HAMAP-Rule:MF_00600] Essential for the growth of the bacteria and the assembly of several bacteriophages. Also plays a role in coupling between replication of the F plasmid and cell division of the cell.[HAMAP-Rule:MF_00600~~] [[https://www.uniprot.org/uniprot/CH10_ECOLI CH10_ECOLI]] Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.[HAMAP-Rule:MF_00580~~]	+	[https://www.uniprot.org/uniprot/CH60_ECOLI CH60_ECOLI] Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.[HAMAP-Rule:MF_00600] Essential for the growth of the bacteria and the assembly of several bacteriophages. Also plays a role in coupling between replication of the F plasmid and cell division of the cell.[HAMAP-Rule:MF_00600]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 26:		Line 26:
	__TOC__		__TOC__
	</SX>		</SX>
-	[[Category: ~~Ecobb~~]]	+	[[Category: Escherichia coli BL21]]
-	[[Category: ~~Ecoli~~]]	+	[[Category: Escherichia coli K-12]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Chen, D H]]	+	[[Category: Chen D-H]]
-	[[Category: Chiu, W]]	+	[[Category: Chiu W]]
-	[[Category: Lin, Z]]	+	[[Category: Lin Z]]
-	[[Category: Madan, D]]	+	[[Category: Madan D]]
-	[[Category: Rye~~, H S~~]]	+	[[Category: Rye HS]]
-	[[Category: Schroder~~, G F~~]]	+	[[Category: Schroder GF]]
-	[[Category: Weaver, J]]	+	[[Category: Weaver J]]
-	~~[[Category: Chaperone]]~~	+
-	~~[[Category: Heterogeneity]]~~	+
-	~~[[Category: Protein folding~~]]	+

OCA at 07:08, 18 August 2022

OCA — Thu, 18 Aug 2022 07:08:56 GMT

←Older revision		Revision as of 07:08, 18 August 2022
Line 3:		Line 3:
	<SX load='3zpz' size='340' side='right' viewer='molstar' caption='[[3zpz]], [[Resolution\|resolution]] 8.90Å' scene=''>		<SX load='3zpz' size='340' side='right' viewer='molstar' caption='[[3zpz]], [[Resolution\|resolution]] 8.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3zpz]] is a 21 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Ecobb Ecobb] and [~~http~~://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZPZ OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=3ZPZ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3zpz]] is a 21 chain structure with sequence from [https://en.wikipedia.org/wiki/Ecobb Ecobb] and [https://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZPZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3ZPZ FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3zq0\|3zq0]], [[3zq1\|3zq1]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3zq0\|3zq0]], [[3zq1\|3zq1]]</div></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=3zpz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zpz OCA], [~~http~~://pdbe.org/3zpz PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3zpz RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3zpz PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3zpz ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3zpz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zpz OCA], [https://pdbe.org/3zpz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3zpz RCSB], [https://www.ebi.ac.uk/pdbsum/3zpz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3zpz ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/CH60_ECOLI CH60_ECOLI]] Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.[HAMAP-Rule:MF_00600] Essential for the growth of the bacteria and the assembly of several bacteriophages. Also plays a role in coupling between replication of the F plasmid and cell division of the cell.[HAMAP-Rule:MF_00600] [[~~http~~://www.uniprot.org/uniprot/CH10_ECOLI CH10_ECOLI]] Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.[HAMAP-Rule:MF_00580]	+	[[https://www.uniprot.org/uniprot/CH60_ECOLI CH60_ECOLI]] Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.[HAMAP-Rule:MF_00600] Essential for the growth of the bacteria and the assembly of several bacteriophages. Also plays a role in coupling between replication of the F plasmid and cell division of the cell.[HAMAP-Rule:MF_00600] [[https://www.uniprot.org/uniprot/CH10_ECOLI CH10_ECOLI]] Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.[HAMAP-Rule:MF_00580]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==

OCA at 18:43, 10 April 2020

OCA — Fri, 10 Apr 2020 18:43:16 GMT

←Older revision		Revision as of 18:43, 10 April 2020
Line 3:		Line 3:
	<SX load='3zpz' size='340' side='right' viewer='molstar' caption='[[3zpz]], [[Resolution\|resolution]] 8.90Å' scene=''>		<SX load='3zpz' size='340' side='right' viewer='molstar' caption='[[3zpz]], [[Resolution\|resolution]] 8.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3zpz]] is a 21 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecobb Ecobb] and [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZPZ OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3ZPZ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3zpz]] is a 21 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecobb Ecobb] and [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZPZ OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=3ZPZ FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3zq0\|3zq0]], [[3zq1\|3zq1]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3zq0\|3zq0]], [[3zq1\|3zq1]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3zpz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zpz OCA], [http://pdbe.org/3zpz PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3zpz RCSB], [http://www.ebi.ac.uk/pdbsum/3zpz PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3zpz ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=3zpz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zpz OCA], [http://pdbe.org/3zpz PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3zpz RCSB], [http://www.ebi.ac.uk/pdbsum/3zpz PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3zpz ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==

OCA at 17:45, 6 March 2020

OCA — Fri, 06 Mar 2020 17:45:01 GMT

←Older revision		Revision as of 17:45, 6 March 2020
Line 1:		Line 1:

	==Visualizing GroEL-ES in the Act of Encapsulating a Non-Native Substrate Protein==		==Visualizing GroEL-ES in the Act of Encapsulating a Non-Native Substrate Protein==
-	<~~StructureSection~~ load='3zpz' size='340' side='right'caption='[[3zpz]], [[Resolution\|resolution]] 8.90Å' scene=''>	+	<SX load='3zpz' size='340' side='right' viewer='molstar' caption='[[3zpz]], [[Resolution\|resolution]] 8.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3zpz]] is a 21 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecobb Ecobb] and [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZPZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ZPZ FirstGlance]. <br>		<table><tr><td colspan='2'>[[3zpz]] is a 21 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecobb Ecobb] and [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZPZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ZPZ FirstGlance]. <br>
Line 25:		Line 25:
	<references/>		<references/>
	__TOC__		__TOC__
-	</~~StructureSection~~>	+	</SX>
	[[Category: Ecobb]]		[[Category: Ecobb]]
	[[Category: Ecoli]]		[[Category: Ecoli]]

OCA at 16:21, 28 August 2019

OCA — Wed, 28 Aug 2019 16:21:51 GMT

←Older revision		Revision as of 16:21, 28 August 2019
Line 1:		Line 1:

	==Visualizing GroEL-ES in the Act of Encapsulating a Non-Native Substrate Protein==		==Visualizing GroEL-ES in the Act of Encapsulating a Non-Native Substrate Protein==
-	<StructureSection load='3zpz' size='340' side='right' caption='[[3zpz]], [[Resolution\|resolution]] 8.90Å' scene=''>	+	<StructureSection load='3zpz' size='340' side='right'caption='[[3zpz]], [[Resolution\|resolution]] 8.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3zpz]] is a 21 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecobb Ecobb] and [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZPZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ZPZ FirstGlance]. <br>		<table><tr><td colspan='2'>[[3zpz]] is a 21 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecobb Ecobb] and [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZPZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ZPZ FirstGlance]. <br>
Line 19:		Line 19:
	</div>		</div>
	<div class="pdbe-citations 3zpz" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 3zpz" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Chaperonin 3D structures\|Chaperonin 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 25:		Line 28:
	[[Category: Ecobb]]		[[Category: Ecobb]]
	[[Category: Ecoli]]		[[Category: Ecoli]]
		+	[[Category: Large Structures]]
	[[Category: Chen, D H]]		[[Category: Chen, D H]]
	[[Category: Chiu, W]]		[[Category: Chiu, W]]

OCA at 22:08, 15 November 2017

OCA — Wed, 15 Nov 2017 22:08:32 GMT

←Older revision		Revision as of 22:08, 15 November 2017
Line 6:		Line 6:
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3zq0\|3zq0]], [[3zq1\|3zq1]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3zq0\|3zq0]], [[3zq1\|3zq1]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3zpz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zpz OCA], [http://pdbe.org/3zpz PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3zpz RCSB], [http://www.ebi.ac.uk/pdbsum/3zpz PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3zpz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zpz OCA], [http://pdbe.org/3zpz PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3zpz RCSB], [http://www.ebi.ac.uk/pdbsum/3zpz PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3zpz ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 19:		Line 19:
	</div>		</div>
	<div class="pdbe-citations 3zpz" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 3zpz" style="background-color:#fffaf0;"></div>
-
-	==See Also==
-	*[[Chaperonin\|Chaperonin]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 05:04, 11 May 2016

OCA — Wed, 11 May 2016 05:04:51 GMT

←Older revision		Revision as of 05:04, 11 May 2016
Line 1:		Line 1:
		+
	==Visualizing GroEL-ES in the Act of Encapsulating a Non-Native Substrate Protein==		==Visualizing GroEL-ES in the Act of Encapsulating a Non-Native Substrate Protein==
	<StructureSection load='3zpz' size='340' side='right' caption='[[3zpz]], [[Resolution\|resolution]] 8.90Å' scene=''>		<StructureSection load='3zpz' size='340' side='right' caption='[[3zpz]], [[Resolution\|resolution]] 8.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3zpz]] is a 21 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Escherichia_coli_bl21 Escherichia coli bl21~~] and [http://en.wikipedia.org/wiki/~~Escherichia_coli_k-12 Escherichia coli k-12~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZPZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ZPZ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3zpz]] is a 21 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecobb Ecobb] and [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZPZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ZPZ FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3zq0\|3zq0]], [[3zq1\|3zq1]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3zq0\|3zq0]], [[3zq1\|3zq1]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3zpz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zpz OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3zpz RCSB], [http://www.ebi.ac.uk/pdbsum/3zpz PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3zpz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zpz OCA], [http://pdbe.org/3zpz PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3zpz RCSB], [http://www.ebi.ac.uk/pdbsum/3zpz PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 17:		Line 18:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3zpz" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 24:		Line 26:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Escherichia coli bl21~~]]	+	[[Category: Ecobb]]
-	[[Category: ~~Escherichia coli k-12~~]]	+	[[Category: Ecoli]]
	[[Category: Chen, D H]]		[[Category: Chen, D H]]
	[[Category: Chiu, W]]		[[Category: Chiu, W]]

OCA at 17:20, 24 December 2014

OCA — Wed, 24 Dec 2014 17:20:01 GMT

←Older revision		Revision as of 17:20, 24 December 2014
Line 7:		Line 7:
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3zpz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zpz OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3zpz RCSB], [http://www.ebi.ac.uk/pdbsum/3zpz PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3zpz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zpz OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3zpz RCSB], [http://www.ebi.ac.uk/pdbsum/3zpz PDBsum]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/CH60_ECOLI CH60_ECOLI]] Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.[HAMAP-Rule:MF_00600] Essential for the growth of the bacteria and the assembly of several bacteriophages. Also plays a role in coupling between replication of the F plasmid and cell division of the cell.[HAMAP-Rule:MF_00600] [[http://www.uniprot.org/uniprot/CH10_ECOLI CH10_ECOLI]] Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.[HAMAP-Rule:MF_00580]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==

OCA at 08:58, 21 December 2014

OCA — Sun, 21 Dec 2014 08:58:50 GMT

←Older revision		Revision as of 08:58, 21 December 2014
Line 1:		Line 1:
-	~~{{STRUCTURE_3zpz\| PDB=3zpz \| SCENE= }}~~	+	==Visualizing GroEL-ES in the Act of Encapsulating a Non-Native Substrate Protein==
-	===Visualizing GroEL-ES in the Act of Encapsulating a Non-Native Substrate Protein===	+	<StructureSection load='3zpz' size='340' side='right' caption='[[3zpz]], [[Resolution\|resolution]] 8.90Å' scene=''>
-	~~{{ABSTRACT_PUBMED_23746846}}~~	+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[3zpz]] is a 21 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli_bl21 Escherichia coli bl21] and [http://en.wikipedia.org/wiki/Escherichia_coli_k-12 Escherichia coli k-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZPZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ZPZ FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3zq0\|3zq0]], [[3zq1\|3zq1]]</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3zpz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zpz OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3zpz RCSB], [http://www.ebi.ac.uk/pdbsum/3zpz PDBsum]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The GroEL/ES chaperonin system is required for the assisted folding of many proteins. How these substrate proteins are encapsulated within the GroEL-GroES cavity is poorly understood. Using symmetry-free, single-particle cryo-electron microscopy, we have characterized a chemically modified mutant of GroEL (EL43Py) that is trapped at a normally transient stage of substrate protein encapsulation. We show that the symmetric pattern of the GroEL subunits is broken as the GroEL cis-ring apical domains reorient to accommodate the simultaneous binding of GroES and an incompletely folded substrate protein (RuBisCO). The collapsed RuBisCO folding intermediate binds to the lower segment of two apical domains, as well as to the normally unstructured GroEL C-terminal tails. A comparative structural analysis suggests that the allosteric transitions leading to substrate protein release and folding involve concerted shifts of GroES and the GroEL apical domains and C-terminal tails.

-	~~==Function==~~	+	Visualizing GroEL/ES in the Act of Encapsulating a Folding Protein.,Chen DH, Madan D, Weaver J, Lin Z, Schroder GF, Chiu W, Rye HS Cell. 2013 Jun 6;153(6):1354-65. doi: 10.1016/j.cell.2013.04.052. PMID:23746846<ref>PMID:23746846</ref>
-	~~[[http:~~/~~/www.uniprot.org/uniprot/CH60_ECOLI CH60_ECOLI]] Prevents misfolding and promotes~~ the ~~refolding and proper assembly~~ of ~~unfolded polypeptides generated under stress conditions~~.~~[HAMAP~~-~~Rule~~:~~MF_00600] Essential for the growth of the bacteria and the assembly of several bacteriophages~~. ~~Also plays a role in coupling between replication of the F plasmid and cell division of the~~ cell.~~[HAMAP-Rule:MF_00600] [[http://www~~.~~uniprot~~.~~org/uniprot/CH10_ECOLI CH10_ECOLI]] Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter~~.~~[HAMAP-Rule~~:~~MF_00580]~~	+

-	~~==About this Structure==~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	~~[[3zpz]] is~~ a ~~21 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Escherichia_coli_bl21 Escherichia coli bl21] and [http://en~~.~~wikipedia.org~~/~~wiki/Escherichia_coli_k-12 Escherichia coli k-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZPZ OCA].~~	+	</div>

-	==~~Reference~~==	+	==See Also==
-	~~<ref group~~=~~"xtra">PMID:023746846</ref>~~<references ~~group="xtra"~~/><~~references~~/>	+	*[[Chaperonin\|Chaperonin]]
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
	[[Category: Escherichia coli bl21]]		[[Category: Escherichia coli bl21]]
	[[Category: Escherichia coli k-12]]		[[Category: Escherichia coli k-12]]
-	[[Category: Chen, D H.]]	+	[[Category: Chen, D H]]
-	[[Category: Chiu, W.]]	+	[[Category: Chiu, W]]
-	[[Category: Lin, Z.]]	+	[[Category: Lin, Z]]
-	[[Category: Madan, D.]]	+	[[Category: Madan, D]]
-	[[Category: Rye, H S.]]	+	[[Category: Rye, H S]]
-	[[Category: Schroder, G F.]]	+	[[Category: Schroder, G F]]
-	[[Category: Weaver, J.]]	+	[[Category: Weaver, J]]
	[[Category: Chaperone]]		[[Category: Chaperone]]
	[[Category: Heterogeneity]]		[[Category: Heterogeneity]]
	[[Category: Protein folding]]		[[Category: Protein folding]]

OCA at 13:32, 19 June 2013

OCA — Wed, 19 Jun 2013 13:32:43 GMT

←Older revision		Revision as of 13:32, 19 June 2013
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	{{STRUCTURE_3zpz\| PDB=3zpz \| SCENE= }}
		+	===Visualizing GroEL-ES in the Act of Encapsulating a Non-Native Substrate Protein===
		+	{{ABSTRACT_PUBMED_23746846}}

-	~~The entry 3zpz is ON HOLD~~	+	==Function==
		+	[[http://www.uniprot.org/uniprot/CH60_ECOLI CH60_ECOLI]] Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.[HAMAP-Rule:MF_00600] Essential for the growth of the bacteria and the assembly of several bacteriophages. Also plays a role in coupling between replication of the F plasmid and cell division of the cell.[HAMAP-Rule:MF_00600] [[http://www.uniprot.org/uniprot/CH10_ECOLI CH10_ECOLI]] Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.[HAMAP-Rule:MF_00580]

-	~~Authors~~: ~~Chen, D~~.-H.~~, Madan, D~~.~~, Weaver, J~~.~~, Lin, Z~~.~~, Schroder, G~~.F.~~, Chiu, W~~.~~, Rye, H.S~~.	+	==About this Structure==
		+	[[3zpz]] is a 21 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli_bl21 Escherichia coli bl21] and [http://en.wikipedia.org/wiki/Escherichia_coli_k-12 Escherichia coli k-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZPZ OCA].

-	~~Description~~: ~~Visualizing GroEL~~-~~ES in the Act of Encapsulating a Non-Native Substrate~~ Protein	+	==Reference==
		+	<ref group="xtra">PMID:023746846</ref><references group="xtra"/><references/>
		+	[[Category: Escherichia coli bl21]]
		+	[[Category: Escherichia coli k-12]]
		+	[[Category: Chen, D H.]]
		+	[[Category: Chiu, W.]]
		+	[[Category: Lin, Z.]]
		+	[[Category: Madan, D.]]
		+	[[Category: Rye, H S.]]
		+	[[Category: Schroder, G F.]]
		+	[[Category: Weaver, J.]]
		+	[[Category: Chaperone]]
		+	[[Category: Heterogeneity]]
		+	[[Category: Protein folding]]