3zrw - Revision history

OCA at 11:11, 20 December 2023

OCA — Wed, 20 Dec 2023 11:11:01 GMT

←Older revision		Revision as of 11:11, 20 December 2023
Line 3:		Line 3:
	<StructureSection load='3zrw' size='340' side='right'caption='[[3zrw]], [[Resolution\|resolution]] 2.25Å' scene=''>		<StructureSection load='3zrw' size='340' side='right'caption='[[3zrw]], [[Resolution\|resolution]] 2.25Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3zrw]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Ecoli Ecoli~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZRW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3ZRW FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3zrw]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Archaeoglobus_fulgidus_DSM_4304 Archaeoglobus fulgidus DSM 4304] and [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZRW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3ZRW FirstGlance]. <br>
-	</td></tr><tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat">~~<div style='overflow: auto; max~~-~~height: 3em;'>[[2y20\|2y20]]~~, [[~~2y0q~~\|~~2y0q~~]]~~, [[2y21\|2y21]], [[2y0t\|2y0t]], [[3zrx\|3zrx]], [[3zrv\|3zrv]]</div></td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.25Å</td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Histidine_kinase Histidine kinase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.~~7.13.3 2.7.13.3] </span>~~</td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3zrw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zrw OCA], [https://pdbe.org/3zrw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3zrw RCSB], [https://www.ebi.ac.uk/pdbsum/3zrw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3zrw ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3zrw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zrw OCA], [https://pdbe.org/3zrw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3zrw RCSB], [https://www.ebi.ac.uk/pdbsum/3zrw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3zrw ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/O28769_ARCFU O28769_ARCFU] [https://www.uniprot.org/uniprot/ENVZ_ECOLI ENVZ_ECOLI] Member of the two-component regulatory system EnvZ/OmpR involved in the regulation of osmoregulation (genes ompF and ompC). EnvZ functions as a membrane-associated protein kinase that phosphorylates OmpR in response to environmental signals.
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 21:		Line 22:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Ecoli~~]]	+	[[Category: Archaeoglobus fulgidus DSM 4304]]
-	[[Category: ~~Histidine kinase~~]]	+	[[Category: Escherichia coli K-12]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Ferris~~, H U~~]]	+	[[Category: Ferris HU]]
-	[[Category: Hulko, M]]	+	[[Category: Hulko M]]
-	[[Category: Lupas~~, A N~~]]	+	[[Category: Lupas AN]]
-	[[Category: Martin, J]]	+	[[Category: Martin J]]
-	[[Category: Zeth, K]]	+	[[Category: Zeth K]]
-	~~[[Category: Ompc]]~~	+
-	~~[[Category: Ompr]]~~	+
-	~~[[Category: Osmoregulation]]~~	+
-	~~[[Category: Signaling protein~~]]	+

OCA at 07:13, 18 August 2022

OCA — Thu, 18 Aug 2022 07:13:07 GMT

←Older revision		Revision as of 07:13, 18 August 2022
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	==The structure of the dimeric Hamp-Dhp fusion A291V mutant==		==The structure of the dimeric Hamp-Dhp fusion A291V mutant==
-	<StructureSection load='3zrw' size='340' side='right' caption='[[3zrw]], [[Resolution\|resolution]] 2.25Å' scene=''>	+	<StructureSection load='3zrw' size='340' side='right'caption='[[3zrw]], [[Resolution\|resolution]] 2.25Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3zrw]] is a 4 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZRW OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3ZRW FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3zrw]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZRW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3ZRW FirstGlance]. <br>
-	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2y20\|2y20]], [[2y0q\|2y0q]], [[2y21\|2y21]], [[2y0t\|2y0t]], [[3zrx\|3zrx]], [[3zrv\|3zrv]]</td></tr>	+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2y20\|2y20]], [[2y0q\|2y0q]], [[2y21\|2y21]], [[2y0t\|2y0t]], [[3zrx\|3zrx]], [[3zrv\|3zrv]]</div></td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/Histidine_kinase Histidine kinase], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.13.3 2.7.13.3] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Histidine_kinase Histidine kinase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.13.3 2.7.13.3] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3zrw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zrw OCA], [~~http~~://pdbe.org/3zrw PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3zrw RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3zrw PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3zrw ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3zrw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zrw OCA], [https://pdbe.org/3zrw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3zrw RCSB], [https://www.ebi.ac.uk/pdbsum/3zrw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3zrw ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 23:		Line 23:
	[[Category: Ecoli]]		[[Category: Ecoli]]
	[[Category: Histidine kinase]]		[[Category: Histidine kinase]]
		+	[[Category: Large Structures]]
	[[Category: Ferris, H U]]		[[Category: Ferris, H U]]
	[[Category: Hulko, M]]		[[Category: Hulko, M]]

OCA at 16:50, 27 February 2019

OCA — Wed, 27 Feb 2019 16:50:46 GMT

←Older revision		Revision as of 16:50, 27 February 2019
Line 3:		Line 3:
	<StructureSection load='3zrw' size='340' side='right' caption='[[3zrw]], [[Resolution\|resolution]] 2.25Å' scene=''>		<StructureSection load='3zrw' size='340' side='right' caption='[[3zrw]], [[Resolution\|resolution]] 2.25Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3zrw]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZRW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ZRW FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3zrw]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZRW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ZRW FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2y20\|2y20]], [[2y0q\|2y0q]], [[2y21\|2y21]], [[2y0t\|2y0t]], [[3zrx\|3zrx]], [[3zrv\|3zrv]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2y20\|2y20]], [[2y0q\|2y0q]], [[2y21\|2y21]], [[2y0t\|2y0t]], [[3zrx\|3zrx]], [[3zrv\|3zrv]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Histidine_kinase Histidine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.13.3 2.7.13.3] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Histidine_kinase Histidine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.13.3 2.7.13.3] </span></td></tr>
Line 21:		Line 21:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Ecoli]]
	[[Category: Histidine kinase]]		[[Category: Histidine kinase]]
	[[Category: Ferris, H U]]		[[Category: Ferris, H U]]

OCA at 13:31, 15 March 2017

OCA — Wed, 15 Mar 2017 13:31:26 GMT

←Older revision		Revision as of 13:31, 15 March 2017
Line 3:		Line 3:
	<StructureSection load='3zrw' size='340' side='right' caption='[[3zrw]], [[Resolution\|resolution]] 2.25Å' scene=''>		<StructureSection load='3zrw' size='340' side='right' caption='[[3zrw]], [[Resolution\|resolution]] 2.25Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3zrw]] is a 4 chain structure ~~with sequence from [http://en.wikipedia.org/wiki/Ecoli Ecoli]~~. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZRW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ZRW FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3zrw]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZRW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ZRW FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2y20\|2y20]], [[2y0q\|2y0q]], [[2y21\|2y21]], [[2y0t\|2y0t]], [[3zrx\|3zrx]], [[3zrv\|3zrv]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2y20\|2y20]], [[2y0q\|2y0q]], [[2y21\|2y21]], [[2y0t\|2y0t]], [[3zrx\|3zrx]], [[3zrv\|3zrv]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Histidine_kinase Histidine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.13.3 2.7.13.3] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Histidine_kinase Histidine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.13.3 2.7.13.3] </span></td></tr>
Line 21:		Line 21:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Ecoli]]
	[[Category: Histidine kinase]]		[[Category: Histidine kinase]]
	[[Category: Ferris, H U]]		[[Category: Ferris, H U]]

OCA at 11:12, 11 August 2016

OCA — Thu, 11 Aug 2016 11:12:34 GMT

←Older revision		Revision as of 11:12, 11 August 2016
Line 1:		Line 1:
		+
	==The structure of the dimeric Hamp-Dhp fusion A291V mutant==		==The structure of the dimeric Hamp-Dhp fusion A291V mutant==
	<StructureSection load='3zrw' size='340' side='right' caption='[[3zrw]], [[Resolution\|resolution]] 2.25Å' scene=''>		<StructureSection load='3zrw' size='340' side='right' caption='[[3zrw]], [[Resolution\|resolution]] 2.25Å' scene=''>
Line 5:		Line 6:
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2y20\|2y20]], [[2y0q\|2y0q]], [[2y21\|2y21]], [[2y0t\|2y0t]], [[3zrx\|3zrx]], [[3zrv\|3zrv]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2y20\|2y20]], [[2y0q\|2y0q]], [[2y21\|2y21]], [[2y0t\|2y0t]], [[3zrx\|3zrx]], [[3zrv\|3zrv]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Histidine_kinase Histidine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.13.3 2.7.13.3] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Histidine_kinase Histidine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.13.3 2.7.13.3] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3zrw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zrw OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3zrw RCSB], [http://www.ebi.ac.uk/pdbsum/3zrw PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3zrw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zrw OCA], [http://pdbe.org/3zrw PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3zrw RCSB], [http://www.ebi.ac.uk/pdbsum/3zrw PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3zrw ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 15:		Line 16:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3zrw" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 09:50, 4 January 2015

OCA — Sun, 04 Jan 2015 09:50:34 GMT

←Older revision		Revision as of 09:50, 4 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3zrw]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZRW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ZRW FirstGlance]. <br>		<table><tr><td colspan='2'>[[3zrw]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZRW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ZRW FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2y20\|2y20]], [[2y0q\|2y0q]], [[2y21\|2y21]], [[2y0t\|2y0t]], [[3zrx\|3zrx]], [[3zrv\|3zrv]]</td></tr>	+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2y20\|2y20]], [[2y0q\|2y0q]], [[2y21\|2y21]], [[2y0t\|2y0t]], [[3zrx\|3zrx]], [[3zrv\|3zrv]]</td></tr>
-	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Histidine_kinase Histidine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.13.3 2.7.13.3] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Histidine_kinase Histidine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.13.3 2.7.13.3] </span></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3zrw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zrw OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3zrw RCSB], [http://www.ebi.ac.uk/pdbsum/3zrw PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3zrw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zrw OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3zrw RCSB], [http://www.ebi.ac.uk/pdbsum/3zrw PDBsum]</span></td></tr>
-	<table>	+	</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 21:		Line 21:
	[[Category: Ecoli]]		[[Category: Ecoli]]
	[[Category: Histidine kinase]]		[[Category: Histidine kinase]]
-	[[Category: Ferris, H U.]]	+	[[Category: Ferris, H U]]
-	[[Category: Hulko, M.]]	+	[[Category: Hulko, M]]
-	[[Category: Lupas, A N.]]	+	[[Category: Lupas, A N]]
-	[[Category: Martin, J.]]	+	[[Category: Martin, J]]
-	[[Category: Zeth, K.]]	+	[[Category: Zeth, K]]
	[[Category: Ompc]]		[[Category: Ompc]]
	[[Category: Ompr]]		[[Category: Ompr]]
	[[Category: Osmoregulation]]		[[Category: Osmoregulation]]
	[[Category: Signaling protein]]		[[Category: Signaling protein]]

OCA at 08:05, 5 June 2014

OCA — Thu, 05 Jun 2014 08:05:00 GMT

←Older revision		Revision as of 08:05, 5 June 2014
Line 1:		Line 1:
-	[[~~Image:~~3zrw.~~png~~\|~~left~~\|~~200px~~]]	+	==The structure of the dimeric Hamp-Dhp fusion A291V mutant==
		+	<StructureSection load='3zrw' size='340' side='right' caption='[[3zrw]], [[Resolution\|resolution]] 2.25Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[3zrw]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZRW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ZRW FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2y20\|2y20]], [[2y0q\|2y0q]], [[2y21\|2y21]], [[2y0t\|2y0t]], [[3zrx\|3zrx]], [[3zrv\|3zrv]]</td></tr>
		+	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Histidine_kinase Histidine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.13.3 2.7.13.3] </span></td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3zrw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zrw OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3zrw RCSB], [http://www.ebi.ac.uk/pdbsum/3zrw PDBsum]</span></td></tr>
		+	<table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Bacterial transmembrane receptors regulate an intracellular catalytic output in response to extracellular sensory input. To investigate the conformational changes that relay the regulatory signal, we have studied the HAMP domain, a ubiquitous intracellular module connecting input to output domains. HAMP forms a parallel, dimeric, four-helical coiled coil, and rational substitutions in our model domain (Af1503 HAMP) induce a transition in its interhelical packing, characterized by axial rotation of all four helices (the gearbox signaling model). We now illustrate how these conformational changes are propagated to a downstream domain by fusing Af1503 HAMP variants to the DHp domain of EnvZ, a bacterial histidine kinase. Structures of wild-type and mutant constructs are correlated with ligand response in vivo, clearly associating them with distinct signaling states. We propose that altered recognition of the catalytic domain by DHp, rather than a shift in position of the phospho-accepting histidine, forms the basis for regulation of kinase activity.

-	<!--	+	Mechanism of regulation of receptor histidine kinases.,Ferris HU, Dunin-Horkawicz S, Hornig N, Hulko M, Martin J, Schultz JE, Zeth K, Lupas AN, Coles M Structure. 2012 Jan 11;20(1):56-66. PMID:22244755<ref>PMID:22244755</ref>
-	~~The line below this paragraph~~, ~~containing "STRUCTURE_3zrw"~~, ~~creates the "~~Structure ~~Box" on the page~~.	+
-	~~You may change the PDB parameter~~ (~~which sets the PDB file loaded into the applet~~)	+
-	~~or the SCENE parameter (which sets the initial scene displayed when the page is loaded),~~	+
-	~~or leave the SCENE parameter empty for the default display.~~	+
-	-->	+
-	~~{{STRUCTURE_3zrw\| PDB=3zrw \| SCENE= }}~~	+

-	~~===The structure~~ of the ~~dimeric Hamp-Dhp fusion A291V mutant===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-		+	== References ==
-	~~<!--~~	+	<references/>
-	~~The line below this paragraph, {{ABSTRACT_PUBMED_22244755}}, adds the Publication Abstract to the page~~	+	__TOC__
-	~~(as it appears on PubMed at http://www~~.~~pubmed~~.~~gov), where 22244755 is the PubMed ID number~~.	+	</StructureSection>
-	-->	+	[[Category: Ecoli]]
-	~~{{ABSTRACT_PUBMED_22244755}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[3zrw]] is a 4 chain structure with sequence from [http:~~//en.wikipedia.org/wiki/Archaeoglobus_fulgidus,_escherichia_coli Archaeoglobus fulgidus, escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZRW OCA].	+
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:022244755<~~/~~ref~~><~~references group="xtra"~~/>	+
-	[[Category: ~~Archaeoglobus fulgidus, escherichia coli~~]]	+
	[[Category: Histidine kinase]]		[[Category: Histidine kinase]]
	[[Category: Ferris, H U.]]		[[Category: Ferris, H U.]]

OCA at 08:14, 25 April 2012

OCA — Wed, 25 Apr 2012 08:14:34 GMT

←Older revision		Revision as of 08:14, 25 April 2012
Line 1:		Line 1:
-	[[Image:3zrw.~~jpg~~\|left\|200px]]	+	[[Image:3zrw.png\|left\|200px]]

	<!--		<!--
Line 9:		Line 9:
	{{STRUCTURE_3zrw\| PDB=3zrw \| SCENE= }}		{{STRUCTURE_3zrw\| PDB=3zrw \| SCENE= }}

-	===~~THE STRUCTURE OF THE DIMERIC HAMP~~-~~DHP FUSION~~ A291V ~~MUTANT~~===	+	===The structure of the dimeric Hamp-Dhp fusion A291V mutant===

		+
		+	<!--
		+	The line below this paragraph, {{ABSTRACT_PUBMED_22244755}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 22244755 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_22244755}}

	==About this Structure==		==About this Structure==
	[[3zrw]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Archaeoglobus_fulgidus,_escherichia_coli Archaeoglobus fulgidus, escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZRW OCA].		[[3zrw]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Archaeoglobus_fulgidus,_escherichia_coli Archaeoglobus fulgidus, escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZRW OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:022244755</ref><references group="xtra"/>
	[[Category: Archaeoglobus fulgidus, escherichia coli]]		[[Category: Archaeoglobus fulgidus, escherichia coli]]
	[[Category: Histidine kinase]]		[[Category: Histidine kinase]]

OCA: Protected "3zrw" [edit=sysop:move=sysop]

OCA — Wed, 29 Jun 2011 06:28:50 GMT

Protected "3zrw" [edit=sysop:move=sysop]

←Older revision

Revision as of 06:28, 29 June 2011