3zs6 - Revision history

OCA at 11:11, 20 December 2023

OCA — Wed, 20 Dec 2023 11:11:19 GMT

←Older revision		Revision as of 11:11, 20 December 2023
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	<StructureSection load='3zs6' size='340' side='right'caption='[[3zs6]], [[Resolution\|resolution]] 2.10Å' scene=''>		<StructureSection load='3zs6' size='340' side='right'caption='[[3zs6]], [[Resolution\|resolution]] 2.10Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3zs6]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/~~"bacillus_pseudomallei"_whitmore_1913 "bacillus~~ pseudomallei~~" whitmore 1913~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZS6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3ZS6 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3zs6]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Burkholderia_pseudomallei Burkholderia pseudomallei] and [https://en.wikipedia.org/wiki/Unidentified Unidentified]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZS6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3ZS6 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.1Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3zs6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zs6 OCA], [https://pdbe.org/3zs6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3zs6 RCSB], [https://www.ebi.ac.uk/pdbsum/3zs6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3zs6 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3zs6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zs6 OCA], [https://pdbe.org/3zs6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3zs6 RCSB], [https://www.ebi.ac.uk/pdbsum/3zs6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3zs6 ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/Q63ID0_BURPS Q63ID0_BURPS]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Bacillus~~ pseudomallei ~~whitmore 1913~~]]	+	[[Category: Burkholderia pseudomallei]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Bolognesi, M~~]]	+	[[Category: Unidentified]]
-	[[Category: ~~Gourlay, L J~~]]	+	[[Category: Bolognesi M]]
-	[[Category: ~~Lassaux, P~~]]	+	[[Category: Gourlay LJ]]
-	[[Category: ~~Abc transport system]]~~	+	[[Category: Lassaux P]]
-	~~[[Category: Peptide binding protein~~]]	+

OCA at 07:13, 18 August 2022

OCA — Thu, 18 Aug 2022 07:13:49 GMT

←Older revision		Revision as of 07:13, 18 August 2022
Line 1:		Line 1:

	==The Structural characterization of Burkholderia pseudomallei OppA.==		==The Structural characterization of Burkholderia pseudomallei OppA.==
-	<StructureSection load='3zs6' size='340' side='right' caption='[[3zs6]], [[Resolution\|resolution]] 2.10Å' scene=''>	+	<StructureSection load='3zs6' size='340' side='right'caption='[[3zs6]], [[Resolution\|resolution]] 2.10Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3zs6]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/"bacillus_pseudomallei"_whitmore_1913 "bacillus pseudomallei" whitmore 1913]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZS6 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3ZS6 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3zs6]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_pseudomallei"_whitmore_1913 "bacillus pseudomallei" whitmore 1913]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZS6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3ZS6 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3zs6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zs6 OCA], [~~http~~://pdbe.org/3zs6 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3zs6 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3zs6 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3zs6 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3zs6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zs6 OCA], [https://pdbe.org/3zs6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3zs6 RCSB], [https://www.ebi.ac.uk/pdbsum/3zs6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3zs6 ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
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	==See Also==		==See Also==
-	*[[~~Oligopeptide-binding protein~~\|~~Oligopeptide-binding protein~~]]	+	*[[ABC transporter 3D structures\|ABC transporter 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 24:		Line 24:
	</StructureSection>		</StructureSection>
	[[Category: Bacillus pseudomallei whitmore 1913]]		[[Category: Bacillus pseudomallei whitmore 1913]]
		+	[[Category: Large Structures]]
	[[Category: Bolognesi, M]]		[[Category: Bolognesi, M]]
	[[Category: Gourlay, L J]]		[[Category: Gourlay, L J]]

OCA at 16:31, 27 February 2019

OCA — Wed, 27 Feb 2019 16:31:32 GMT

←Older revision		Revision as of 16:31, 27 February 2019
Line 16:		Line 16:
	</div>		</div>
	<div class="pdbe-citations 3zs6" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 3zs6" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Oligopeptide-binding protein\|Oligopeptide-binding protein]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 19:06, 10 December 2016

OCA — Sat, 10 Dec 2016 19:06:38 GMT

←Older revision		Revision as of 19:06, 10 December 2016
Line 1:		Line 1:
		+
	==The Structural characterization of Burkholderia pseudomallei OppA.==		==The Structural characterization of Burkholderia pseudomallei OppA.==
	<StructureSection load='3zs6' size='340' side='right' caption='[[3zs6]], [[Resolution\|resolution]] 2.10Å' scene=''>		<StructureSection load='3zs6' size='340' side='right' caption='[[3zs6]], [[Resolution\|resolution]] 2.10Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3zs6]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Burkholderia_pseudomallei Burkholderia~~ pseudomallei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZS6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ZS6 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3zs6]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_pseudomallei"_whitmore_1913 "bacillus pseudomallei" whitmore 1913]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZS6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ZS6 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3zs6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zs6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3zs6 RCSB], [http://www.ebi.ac.uk/pdbsum/3zs6 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3zs6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zs6 OCA], [http://pdbe.org/3zs6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3zs6 RCSB], [http://www.ebi.ac.uk/pdbsum/3zs6 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3zs6 ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 14:		Line 15:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3zs6" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Burkholderia~~ pseudomallei]]	+	[[Category: Bacillus pseudomallei whitmore 1913]]
	[[Category: Bolognesi, M]]		[[Category: Bolognesi, M]]
	[[Category: Gourlay, L J]]		[[Category: Gourlay, L J]]

OCA at 15:02, 9 December 2014

OCA — Tue, 09 Dec 2014 15:02:48 GMT

←Older revision		Revision as of 15:02, 9 December 2014
Line 1:		Line 1:
-	[[~~Image:~~3zs6.~~png~~\|~~left\|200px~~]]	+	==The Structural characterization of Burkholderia pseudomallei OppA.==
		+	<StructureSection load='3zs6' size='340' side='right' caption='[[3zs6]], [[Resolution\|resolution]] 2.10Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[3zs6]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Burkholderia_pseudomallei Burkholderia pseudomallei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZS6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ZS6 FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3zs6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zs6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3zs6 RCSB], [http://www.ebi.ac.uk/pdbsum/3zs6 PDBsum]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	We present an approach integrating structural and computational biology with immunological tests to identify epitopes in the OppA antigen from the Gram-negative pathogen Burkholderia pseudomallei, the etiological agent of melioidosis. The crystal structure of OppA(Bp), reported here at 2.1 A resolution, was the basis for a computational analysis that identified three potential epitopes. In parallel, antigen proteolysis and immunocapturing allowed us to identify three additional peptides. All six potential epitopes were synthesized as free peptides and tested for their immunoreactivity against sera from healthy seronegative, healthy seropositive, and recovered melioidosis patients. Three synthetic peptides allowed the different patient groups to be distinguished, underlining the potential of this approach. Extension of the computational analysis, including energy-based decomposition methods, allowed rationalizing results of the predictive analyses and the immunocapture epitope mapping. Our results illustrate a structure-based epitope discovery process, whose application may expand our perspectives in the diagnostic and vaccine design fields.

-	~~{{STRUCTURE_3zs6\| PDB=3zs6 \| SCENE= }}~~	+	A Structure-Based Strategy for Epitope Discovery in Burkholderia pseudomallei OppA Antigen.,Lassaux P, Peri C, Ferrer-Navarro M, Gourlay LJ, Gori A, Conchillo-Sole O, Rinchai D, Lertmemongkolchai G, Longhi R, Daura X, Colombo G, Bolognesi M Structure. 2012 Nov 13. pii: S0969-2126(12)00379-6. doi:, 10.1016/j.str.2012.10.005. PMID:23159127<ref>PMID:23159127</ref>

-	~~===The Structural characterization~~ of ~~Burkholderia pseudomallei OppA~~.~~===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_23159127}}~~	+	== References ==
-		+	<references/>
-	==~~About this Structure~~==	+	__TOC__
-	~~[[3zs6]] is a 2 chain structure with sequence from [http:~~//~~en.wikipedia.org/wiki/Burkholderia_pseudomallei Burkholderia pseudomallei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZS6 OCA].~~	+	</StructureSection>
	[[Category: Burkholderia pseudomallei]]		[[Category: Burkholderia pseudomallei]]
-	[[Category: Bolognesi, M.]]	+	[[Category: Bolognesi, M]]
-	[[Category: Gourlay, L J.]]	+	[[Category: Gourlay, L J]]
-	[[Category: Lassaux, P.]]	+	[[Category: Lassaux, P]]
	[[Category: Abc transport system]]		[[Category: Abc transport system]]
	[[Category: Peptide binding protein]]		[[Category: Peptide binding protein]]

OCA at 08:09, 9 January 2013

OCA — Wed, 09 Jan 2013 08:09:27 GMT

←Older revision		Revision as of 08:09, 9 January 2013
Line 1:		Line 1:
-	[[Image:3zs6.~~jpg~~\|left\|200px]]	+	[[Image:3zs6.png\|left\|200px]]

	{{STRUCTURE_3zs6\| PDB=3zs6 \| SCENE= }}		{{STRUCTURE_3zs6\| PDB=3zs6 \| SCENE= }}
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	===The Structural characterization of Burkholderia pseudomallei OppA.===		===The Structural characterization of Burkholderia pseudomallei OppA.===

		+	{{ABSTRACT_PUBMED_23159127}}

	==About this Structure==		==About this Structure==
Line 10:		Line 11:
	[[Category: Burkholderia pseudomallei]]		[[Category: Burkholderia pseudomallei]]
	[[Category: Bolognesi, M.]]		[[Category: Bolognesi, M.]]
-	[[Category: Gourlay, L.]]	+	[[Category: Gourlay, L J.]]
	[[Category: Lassaux, P.]]		[[Category: Lassaux, P.]]
	[[Category: Abc transport system]]		[[Category: Abc transport system]]
	[[Category: Peptide binding protein]]		[[Category: Peptide binding protein]]

OCA at 07:45, 4 July 2012

OCA — Wed, 04 Jul 2012 07:45:43 GMT

←Older revision		Revision as of 07:45, 4 July 2012
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	[[Image:3zs6.jpg\|left\|200px]]

-	~~The entry~~ 3zs6 ~~is ON HOLD~~ ~~until Paper Publication~~	+	{{STRUCTURE_3zs6\| PDB=3zs6 \| SCENE= }}

-	~~Authors: Lassaux, P., Gourlay, L., Bolognesi, M~~.	+	===The Structural characterization of Burkholderia pseudomallei OppA.===

-	~~Description~~: ~~The Structural characterization of~~ Burkholderia pseudomallei ~~OppA~~.	+
		+	==About this Structure==
		+	[[3zs6]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Burkholderia_pseudomallei Burkholderia pseudomallei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZS6 OCA].
		+	[[Category: Burkholderia pseudomallei]]
		+	[[Category: Bolognesi, M.]]
		+	[[Category: Gourlay, L.]]
		+	[[Category: Lassaux, P.]]
		+	[[Category: Abc transport system]]
		+	[[Category: Peptide binding protein]]

OCA at 08:17, 29 February 2012

OCA — Wed, 29 Feb 2012 08:17:28 GMT

←Older revision		Revision as of 08:17, 29 February 2012
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 3zs6 is ON HOLD	+	The entry 3zs6 is ON HOLD until Paper Publication

	Authors: Lassaux, P., Gourlay, L., Bolognesi, M.		Authors: Lassaux, P., Gourlay, L., Bolognesi, M.

	Description: The Structural characterization of Burkholderia pseudomallei OppA.		Description: The Structural characterization of Burkholderia pseudomallei OppA.

OCA: Protected "3zs6" [edit=sysop:move=sysop]

OCA — Wed, 29 Jun 2011 05:49:52 GMT

Protected "3zs6" [edit=sysop:move=sysop]

←Older revision

Revision as of 05:49, 29 June 2011

OCA: New page: '''Unreleased structure''' The entry 3zs6 is ON HOLD Authors: Lassaux, P., Gourlay, L., Bolognesi, M. Description: The Structural characterization of Burkholderia pseudomallei OppA.

OCA — Wed, 29 Jun 2011 05:49:51 GMT

New page: '''Unreleased structure''' The entry 3zs6 is ON HOLD Authors: Lassaux, P., Gourlay, L., Bolognesi, M. Description: The Structural characterization of Burkholderia pseudomallei OppA.

New page

'''Unreleased structure'''

The entry 3zs6 is ON HOLD

Authors: Lassaux, P., Gourlay, L., Bolognesi, M.

Description: The Structural characterization of Burkholderia pseudomallei OppA.