3zua - Revision history

OCA at 07:18, 18 August 2022

OCA — Thu, 18 Aug 2022 07:18:30 GMT

←Older revision		Revision as of 07:18, 18 August 2022
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	==A C39-like domain==		==A C39-like domain==
-	<StructureSection load='3zua' size='340' side='right' caption='[[3zua]], [[NMR_Ensembles_of_Models \| 10 NMR models]]' scene=''>	+	<StructureSection load='3zua' size='340' side='right'caption='[[3zua]], [[NMR_Ensembles_of_Models \| 10 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3zua]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZUA OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3ZUA FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3zua]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZUA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3ZUA FirstGlance]. <br>
-	</td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/Papain Papain], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.22.2 3.4.22.2] </span></td></tr>	+	</td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Papain Papain], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.22.2 3.4.22.2] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3zua FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zua OCA], [~~http~~://pdbe.org/3zua PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3zua RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3zua PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3zua ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3zua FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zua OCA], [https://pdbe.org/3zua PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3zua RCSB], [https://www.ebi.ac.uk/pdbsum/3zua PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3zua ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/HLYB3_ECOLX HLYB3_ECOLX]] Part of the ABC transporter complex HlyBD involved in hemolysin export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity).	+	[[https://www.uniprot.org/uniprot/HLYB3_ECOLX HLYB3_ECOLX]] Part of the ABC transporter complex HlyBD involved in hemolysin export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity).
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	</div>		</div>
	<div class="pdbe-citations 3zua" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 3zua" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[ABC transporter 3D structures\|ABC transporter 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
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	</StructureSection>		</StructureSection>
	[[Category: Bacillus coli migula 1895]]		[[Category: Bacillus coli migula 1895]]
		+	[[Category: Large Structures]]
	[[Category: Papain]]		[[Category: Papain]]
	[[Category: Lecher, J]]		[[Category: Lecher, J]]

OCA at 21:24, 4 August 2016

OCA — Thu, 04 Aug 2016 21:24:27 GMT

←Older revision		Revision as of 21:24, 4 August 2016
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		+
	==A C39-like domain==		==A C39-like domain==
	<StructureSection load='3zua' size='340' side='right' caption='[[3zua]], [[NMR_Ensembles_of_Models \| 10 NMR models]]' scene=''>		<StructureSection load='3zua' size='340' side='right' caption='[[3zua]], [[NMR_Ensembles_of_Models \| 10 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3zua]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Escherichia_coli Escherichia~~ coli]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZUA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ZUA FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3zua]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZUA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ZUA FirstGlance]. <br>
	</td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Papain Papain], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.22.2 3.4.22.2] </span></td></tr>		</td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Papain Papain], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.22.2 3.4.22.2] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3zua FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zua OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3zua RCSB], [http://www.ebi.ac.uk/pdbsum/3zua PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3zua FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zua OCA], [http://pdbe.org/3zua PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3zua RCSB], [http://www.ebi.ac.uk/pdbsum/3zua PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3zua ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
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	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3zua" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Escherichia~~ coli]]	+	[[Category: Bacillus coli migula 1895]]
	[[Category: Papain]]		[[Category: Papain]]
	[[Category: Lecher, J]]		[[Category: Lecher, J]]

OCA at 19:47, 24 December 2014

OCA — Wed, 24 Dec 2014 19:47:37 GMT

←Older revision		Revision as of 19:47, 24 December 2014
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	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3zua FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zua OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3zua RCSB], [http://www.ebi.ac.uk/pdbsum/3zua PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3zua FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zua OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3zua RCSB], [http://www.ebi.ac.uk/pdbsum/3zua PDBsum]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/HLYB3_ECOLX HLYB3_ECOLX]] Part of the ABC transporter complex HlyBD involved in hemolysin export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity).
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==

OCA at 14:38, 9 December 2014

OCA — Tue, 09 Dec 2014 14:38:38 GMT

←Older revision		Revision as of 14:38, 9 December 2014
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-	[[~~Image~~:3zua.~~png\|left\|200px~~]]	+	==A C39-like domain==
		+	<StructureSection load='3zua' size='340' side='right' caption='[[3zua]], [[NMR_Ensembles_of_Models \| 10 NMR models]]' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[3zua]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZUA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ZUA FirstGlance]. <br>
		+	</td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Papain Papain], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.22.2 3.4.22.2] </span></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3zua FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zua OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3zua RCSB], [http://www.ebi.ac.uk/pdbsum/3zua PDBsum]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Type 1 secretion systems (T1SS) catalyze the one step protein transport across the membranes of Gram-negative bacteria and are composed of an outer membrane protein, a membrane fusion protein and an ABC transporter. The ABC transporter consists of the canonical nucleotide binding and transmembrane domains. For the toxin hemolysin A (HlyA), the ABC transporter HlyB carries an additional, N-terminal domain sharing about 40% homology to C39 peptidases, but this "C39-like domain" (CLD) is suggested to feature another, yet unknown function. Our functional and structural analysis demonstrates that the CLD is essential for secretion and that it specifically interacts with the unfolded state of HlyA. We determined the nuclear magnetic resonance structure of the CLD as well as the substrate-binding region within the CLD. This mode of action, represents a mechanism within T1SS and answers the question, how a large and unfolded substrate is protected inside the cells during secretion.

-	~~{{STRUCTURE_3zua\| PDB=3zua \| SCENE= }}~~	+	An RTX Transporter Tethers Its Unfolded Substrate during Secretion via a Unique N-Terminal Domain.,Lecher J, Schwarz CK, Stoldt M, Smits SH, Willbold D, Schmitt L Structure. 2012 Sep 5. PMID:22959622<ref>PMID:22959622</ref>

-	~~===A C39-like domain===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_22959622}}~~	+	== References ==
-		+	<references/>
-	==~~About this Structure~~==	+	__TOC__
-	~~[[3zua]] is a 1 chain structure with sequence from [http:~~//~~en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZUA OCA].~~	+	</StructureSection>
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
	[[Category: Papain]]		[[Category: Papain]]
-	[[Category: Lecher, J.]]	+	[[Category: Lecher, J]]
-	[[Category: Schmitt, L.]]	+	[[Category: Schmitt, L]]
-	[[Category: Schwarz, C K.W.]]	+	[[Category: Schwarz, C K.W]]
-	[[Category: Smits, S S.H.]]	+	[[Category: Smits, S S.H]]
-	[[Category: Stoldt, M.]]	+	[[Category: Stoldt, M]]
-	[[Category: Willbold, D.]]	+	[[Category: Willbold, D]]
	[[Category: Abc transporter]]		[[Category: Abc transporter]]
	[[Category: C39 peptidase-like domain]]		[[Category: C39 peptidase-like domain]]

OCA at 10:40, 14 November 2012

OCA — Wed, 14 Nov 2012 10:40:09 GMT

←Older revision		Revision as of 10:40, 14 November 2012
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	===A C39-like domain===		===A C39-like domain===

		+	{{ABSTRACT_PUBMED_22959622}}

	==About this Structure==		==About this Structure==

OCA at 14:10, 8 November 2012

OCA — Thu, 08 Nov 2012 14:10:09 GMT

←Older revision		Revision as of 14:10, 8 November 2012
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	{{STRUCTURE_3zua\| PDB=3zua \| SCENE= }}		{{STRUCTURE_3zua\| PDB=3zua \| SCENE= }}

-	===~~Initial recognition steps of the type I secretion system~~===	+	===A C39-like domain===

-	{{ABSTRACT_PUBMED_22959622}}

	==About this Structure==		==About this Structure==

OCA at 09:32, 31 October 2012

OCA — Wed, 31 Oct 2012 09:32:46 GMT

←Older revision		Revision as of 09:32, 31 October 2012
Line 8:		Line 8:

	==About this Structure==		==About this Structure==
-	[[3zua]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZUA OCA].	+	[[3zua]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZUA OCA].
		+	[[Category: Escherichia coli]]
	[[Category: Papain]]		[[Category: Papain]]
	[[Category: Lecher, J.]]		[[Category: Lecher, J.]]

OCA at 06:29, 10 October 2012

OCA — Wed, 10 Oct 2012 06:29:58 GMT

←Older revision		Revision as of 06:29, 10 October 2012
Line 5:		Line 5:
	===Initial recognition steps of the type I secretion system===		===Initial recognition steps of the type I secretion system===

		+	{{ABSTRACT_PUBMED_22959622}}

	==About this Structure==		==About this Structure==
-	[[3zua]] is a 1 chain structure ~~with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]~~. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZUA OCA].	+	[[3zua]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZUA OCA].
-	~~[[Category: Escherichia coli]]~~	+
	[[Category: Papain]]		[[Category: Papain]]
	[[Category: Lecher, J.]]		[[Category: Lecher, J.]]

OCA at 05:36, 29 August 2012

OCA — Wed, 29 Aug 2012 05:36:38 GMT

←Older revision		Revision as of 05:36, 29 August 2012
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-	[[Image:3zua.~~jpg~~\|left\|200px]]	+	[[Image:3zua.png\|left\|200px]]

	{{STRUCTURE_3zua\| PDB=3zua \| SCENE= }}		{{STRUCTURE_3zua\| PDB=3zua \| SCENE= }}

OCA at 05:58, 1 August 2012

OCA — Wed, 01 Aug 2012 05:58:09 GMT

←Older revision		Revision as of 05:58, 1 August 2012
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-	~~'''Unreleased structure'''~~	+	[[Image:3zua.jpg\|left\|200px]]

-	~~The entry~~ 3zua ~~is ON HOLD~~ ~~until Paper Publication~~	+	{{STRUCTURE_3zua\| PDB=3zua \| SCENE= }}

-	~~Authors: Lecher, J., Schwarz, C.K.W., Stoldt, M., Smits, S.S.H., Willbold, D., Schmitt, L.~~	+	===Initial recognition steps of the type I secretion system===

-	~~Description~~: ~~Initial recognition steps of the type I secretion system~~	+
		+	==About this Structure==
		+	[[3zua]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZUA OCA].
		+	[[Category: Escherichia coli]]
		+	[[Category: Papain]]
		+	[[Category: Lecher, J.]]
		+	[[Category: Schmitt, L.]]
		+	[[Category: Schwarz, C K.W.]]
		+	[[Category: Smits, S S.H.]]
		+	[[Category: Stoldt, M.]]
		+	[[Category: Willbold, D.]]
		+	[[Category: Abc transporter]]
		+	[[Category: C39 peptidase-like domain]]
		+	[[Category: Haemolysin]]
		+	[[Category: Heteronuclear nmr]]
		+	[[Category: Hydrolase]]