3zut - Revision history

OCA at 11:13, 20 December 2023

OCA — Wed, 20 Dec 2023 11:13:41 GMT

←Older revision		Revision as of 11:13, 20 December 2023
Line 3:		Line 3:
	<StructureSection load='3zut' size='340' side='right'caption='[[3zut]], [[Resolution\|resolution]] 2.50Å' scene=''>		<StructureSection load='3zut' size='340' side='right'caption='[[3zut]], [[Resolution\|resolution]] 2.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3zut]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Arath Arath~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZUT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3ZUT FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3zut]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZUT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3ZUT FirstGlance]. <br>
-	</td></tr><tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"~~><div style='overflow: auto; max-height: 3em;'>[[3zuu\|3zuu]]</div></td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.5Å</td></tr>
-	~~<tr~~ id~~='gene'><td class~~="~~sblockLbl~~">~~<b>~~[[~~Gene~~\|~~Gene:~~]]~~</b></td><td class="sblockDat">SRK2E, OST1, SNRK2~~.~~6, At4g33950, F17I5.140 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=~~5&~~id=3702 ARATH])</td></tr>~~	+
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3zut FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zut OCA], [https://pdbe.org/3zut PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3zut RCSB], [https://www.ebi.ac.uk/pdbsum/3zut PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3zut ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3zut FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zut OCA], [https://pdbe.org/3zut PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3zut RCSB], [https://www.ebi.ac.uk/pdbsum/3zut PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3zut ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/SRK2E_ARATH SRK2E_ARATH]] Activator of the abscisic acid (ABA) signaling pathway that regulates numerous ABA responses, such as stomata closure in response to drought, plant pathogens, or decreases in atmospheric relative humidity (RH). Involved in the resistance to drought by avoiding water loss. Required for the stomata closure mediated by pathogen-associated molecular pattern (PAMPs) (e.g. flg22 and LPS) of pathogenic bacteria such as P.syringae pv. tomato (Pst) and E.coli O157:H7. As a plant defense process, stomata are closed transiently in order to limit invaders, but actively reopened by bacteria after a few hours; virulent strains (e.g. Pst DC3000) are more efficient than avirulent strains (e.g. Pst DC3000 AvrRpt2) in reopening stomata. Mediates the phosphorylation and activation of the S-type anion efflux channel SLAC1, and thus promotes stomata closure. Essential for stomatal closure in response to reactive oxygen species (ROS).<ref>PMID:12468729</ref> <ref>PMID:12514244</ref> <ref>PMID:12047634</ref> <ref>PMID:15064385</ref> <ref>PMID:16959575</ref> <ref>PMID:16682349</ref> <ref>PMID:16365038</ref> <ref>PMID:16766677</ref> <ref>PMID:17307925</ref> <ref>PMID:19955427</ref> <ref>PMID:19955405</ref> <ref>PMID:20128877</ref>	+	[https://www.uniprot.org/uniprot/SRK2E_ARATH SRK2E_ARATH] Activator of the abscisic acid (ABA) signaling pathway that regulates numerous ABA responses, such as stomata closure in response to drought, plant pathogens, or decreases in atmospheric relative humidity (RH). Involved in the resistance to drought by avoiding water loss. Required for the stomata closure mediated by pathogen-associated molecular pattern (PAMPs) (e.g. flg22 and LPS) of pathogenic bacteria such as P.syringae pv. tomato (Pst) and E.coli O157:H7. As a plant defense process, stomata are closed transiently in order to limit invaders, but actively reopened by bacteria after a few hours; virulent strains (e.g. Pst DC3000) are more efficient than avirulent strains (e.g. Pst DC3000 AvrRpt2) in reopening stomata. Mediates the phosphorylation and activation of the S-type anion efflux channel SLAC1, and thus promotes stomata closure. Essential for stomatal closure in response to reactive oxygen species (ROS).<ref>PMID:12468729</ref> <ref>PMID:12514244</ref> <ref>PMID:12047634</ref> <ref>PMID:15064385</ref> <ref>PMID:16959575</ref> <ref>PMID:16682349</ref> <ref>PMID:16365038</ref> <ref>PMID:16766677</ref> <ref>PMID:17307925</ref> <ref>PMID:19955427</ref> <ref>PMID:19955405</ref> <ref>PMID:20128877</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Arath~~]]	+	[[Category: Arabidopsis thaliana]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	~~[[Category: Non-specific serine/threonine protein kinase]]~~	+	[[Category: Albert A]]
-	[[Category: Albert, A]]	+	[[Category: Martinez-Ripoll M]]
-	[[Category: Martinez-Ripoll, M]]	+	[[Category: Yunta C]]
-	[[Category: Yunta, C]]	+
-	~~[[Category: Kinase regulation]]~~	+
-	~~[[Category: Plant abiotic stress]]~~	+
-	~~[[Category: Signaling]]~~	+
-	~~[[Category: Transferase~~]]	+

OCA at 07:19, 18 August 2022

OCA — Thu, 18 Aug 2022 07:19:48 GMT

←Older revision		Revision as of 07:19, 18 August 2022
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	==The structure of OST1 (D160A) kinase==		==The structure of OST1 (D160A) kinase==
-	<StructureSection load='3zut' size='340' side='right' caption='[[3zut]], [[Resolution\|resolution]] 2.50Å' scene=''>	+	<StructureSection load='3zut' size='340' side='right'caption='[[3zut]], [[Resolution\|resolution]] 2.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3zut]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Arath Arath]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZUT OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3ZUT FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3zut]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Arath Arath]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZUT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3ZUT FirstGlance]. <br>
-	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3zuu\|3zuu]]</td></tr>	+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3zuu\|3zuu]]</div></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">SRK2E, OST1, SNRK2.6, At4g33950, F17I5.140 ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=3702 ARATH])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">SRK2E, OST1, SNRK2.6, At4g33950, F17I5.140 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=3702 ARATH])</td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3zut FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zut OCA], [~~http~~://pdbe.org/3zut PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3zut RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3zut PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3zut ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3zut FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zut OCA], [https://pdbe.org/3zut PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3zut RCSB], [https://www.ebi.ac.uk/pdbsum/3zut PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3zut ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/SRK2E_ARATH SRK2E_ARATH]] Activator of the abscisic acid (ABA) signaling pathway that regulates numerous ABA responses, such as stomata closure in response to drought, plant pathogens, or decreases in atmospheric relative humidity (RH). Involved in the resistance to drought by avoiding water loss. Required for the stomata closure mediated by pathogen-associated molecular pattern (PAMPs) (e.g. flg22 and LPS) of pathogenic bacteria such as P.syringae pv. tomato (Pst) and E.coli O157:H7. As a plant defense process, stomata are closed transiently in order to limit invaders, but actively reopened by bacteria after a few hours; virulent strains (e.g. Pst DC3000) are more efficient than avirulent strains (e.g. Pst DC3000 AvrRpt2) in reopening stomata. Mediates the phosphorylation and activation of the S-type anion efflux channel SLAC1, and thus promotes stomata closure. Essential for stomatal closure in response to reactive oxygen species (ROS).<ref>PMID:12468729</ref> <ref>PMID:12514244</ref> <ref>PMID:12047634</ref> <ref>PMID:15064385</ref> <ref>PMID:16959575</ref> <ref>PMID:16682349</ref> <ref>PMID:16365038</ref> <ref>PMID:16766677</ref> <ref>PMID:17307925</ref> <ref>PMID:19955427</ref> <ref>PMID:19955405</ref> <ref>PMID:20128877</ref>	+	[[https://www.uniprot.org/uniprot/SRK2E_ARATH SRK2E_ARATH]] Activator of the abscisic acid (ABA) signaling pathway that regulates numerous ABA responses, such as stomata closure in response to drought, plant pathogens, or decreases in atmospheric relative humidity (RH). Involved in the resistance to drought by avoiding water loss. Required for the stomata closure mediated by pathogen-associated molecular pattern (PAMPs) (e.g. flg22 and LPS) of pathogenic bacteria such as P.syringae pv. tomato (Pst) and E.coli O157:H7. As a plant defense process, stomata are closed transiently in order to limit invaders, but actively reopened by bacteria after a few hours; virulent strains (e.g. Pst DC3000) are more efficient than avirulent strains (e.g. Pst DC3000 AvrRpt2) in reopening stomata. Mediates the phosphorylation and activation of the S-type anion efflux channel SLAC1, and thus promotes stomata closure. Essential for stomatal closure in response to reactive oxygen species (ROS).<ref>PMID:12468729</ref> <ref>PMID:12514244</ref> <ref>PMID:12047634</ref> <ref>PMID:15064385</ref> <ref>PMID:16959575</ref> <ref>PMID:16682349</ref> <ref>PMID:16365038</ref> <ref>PMID:16766677</ref> <ref>PMID:17307925</ref> <ref>PMID:19955427</ref> <ref>PMID:19955405</ref> <ref>PMID:20128877</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 22:		Line 22:

	==See Also==		==See Also==
-	*[[ABA-regulated SNRK2 Protein Kinase\|ABA-regulated SNRK2 Protein Kinase]]	+	*[[Serine/threonine protein kinase 3D structures\|Serine/threonine protein kinase 3D structures]]
-	*[[Serine/threonine protein kinase\|Serine/threonine protein kinase]]	+
	== References ==		== References ==
	<references/>		<references/>
Line 29:		Line 28:
	</StructureSection>		</StructureSection>
	[[Category: Arath]]		[[Category: Arath]]
		+	[[Category: Large Structures]]
	[[Category: Non-specific serine/threonine protein kinase]]		[[Category: Non-specific serine/threonine protein kinase]]
	[[Category: Albert, A]]		[[Category: Albert, A]]

OCA at 06:13, 24 October 2018

OCA — Wed, 24 Oct 2018 06:13:05 GMT

←Older revision		Revision as of 06:13, 24 October 2018
Line 1:		Line 1:

-	==~~THE STRUCTURE OF~~ OST1 (D160A) ~~KINASE~~==	+	==The structure of OST1 (D160A) kinase==
	<StructureSection load='3zut' size='340' side='right' caption='[[3zut]], [[Resolution\|resolution]] 2.50Å' scene=''>		<StructureSection load='3zut' size='340' side='right' caption='[[3zut]], [[Resolution\|resolution]] 2.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3zut]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Arabidopsis_thaliana Arabidopsis thaliana~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZUT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ZUT FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3zut]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Arath Arath]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZUT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ZUT FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3zuu\|3zuu]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3zuu\|3zuu]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">SRK2E, OST1, SNRK2.6, At4g33950, F17I5.140 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=3702 ARATH])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3zut FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zut OCA], [http://pdbe.org/3zut PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3zut RCSB], [http://www.ebi.ac.uk/pdbsum/3zut PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3zut ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3zut FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zut OCA], [http://pdbe.org/3zut PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3zut RCSB], [http://www.ebi.ac.uk/pdbsum/3zut PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3zut ProSAT]</span></td></tr>
Line 27:		Line 28:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Arabidopsis thaliana~~]]	+	[[Category: Arath]]
	[[Category: Non-specific serine/threonine protein kinase]]		[[Category: Non-specific serine/threonine protein kinase]]
	[[Category: Albert, A]]		[[Category: Albert, A]]

OCA at 15:13, 4 August 2016

OCA — Thu, 04 Aug 2016 15:13:01 GMT

←Older revision		Revision as of 15:13, 4 August 2016
Line 1:		Line 1:
		+
	==THE STRUCTURE OF OST1 (D160A) KINASE==		==THE STRUCTURE OF OST1 (D160A) KINASE==
	<StructureSection load='3zut' size='340' side='right' caption='[[3zut]], [[Resolution\|resolution]] 2.50Å' scene=''>		<StructureSection load='3zut' size='340' side='right' caption='[[3zut]], [[Resolution\|resolution]] 2.50Å' scene=''>
Line 5:		Line 6:
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3zuu\|3zuu]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3zuu\|3zuu]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3zut FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zut OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3zut RCSB], [http://www.ebi.ac.uk/pdbsum/3zut PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3zut FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zut OCA], [http://pdbe.org/3zut PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3zut RCSB], [http://www.ebi.ac.uk/pdbsum/3zut PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3zut ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 17:		Line 18:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3zut" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==

OCA at 16:14, 24 December 2014

OCA — Wed, 24 Dec 2014 16:14:14 GMT

←Older revision		Revision as of 16:14, 24 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3zut]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZUT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ZUT FirstGlance]. <br>		<table><tr><td colspan='2'>[[3zut]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZUT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ZUT FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3zuu\|3zuu]]</td></tr>	+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3zuu\|3zuu]]</td></tr>
-	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3zut FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zut OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3zut RCSB], [http://www.ebi.ac.uk/pdbsum/3zut PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3zut FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zut OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3zut RCSB], [http://www.ebi.ac.uk/pdbsum/3zut PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/SRK2E_ARATH SRK2E_ARATH]] Activator of the abscisic acid (ABA) signaling pathway that regulates numerous ABA responses, such as stomata closure in response to drought, plant pathogens, or decreases in atmospheric relative humidity (RH). Involved in the resistance to drought by avoiding water loss. Required for the stomata closure mediated by pathogen-associated molecular pattern (PAMPs) (e.g. flg22 and LPS) of pathogenic bacteria such as P.syringae pv. tomato (Pst) and E.coli O157:H7. As a plant defense process, stomata are closed transiently in order to limit invaders, but actively reopened by bacteria after a few hours; virulent strains (e.g. Pst DC3000) are more efficient than avirulent strains (e.g. Pst DC3000 AvrRpt2) in reopening stomata. Mediates the phosphorylation and activation of the S-type anion efflux channel SLAC1, and thus promotes stomata closure. Essential for stomatal closure in response to reactive oxygen species (ROS).<ref>PMID:12468729</ref> <ref>PMID:12514244</ref> <ref>PMID:12047634</ref> <ref>PMID:15064385</ref> <ref>PMID:16959575</ref> <ref>PMID:16682349</ref> <ref>PMID:16365038</ref> <ref>PMID:16766677</ref> <ref>PMID:17307925</ref> <ref>PMID:19955427</ref> <ref>PMID:19955405</ref> <ref>PMID:20128877</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 25:		Line 27:
	[[Category: Arabidopsis thaliana]]		[[Category: Arabidopsis thaliana]]
	[[Category: Non-specific serine/threonine protein kinase]]		[[Category: Non-specific serine/threonine protein kinase]]
-	[[Category: Albert, A.]]	+	[[Category: Albert, A]]
-	[[Category: Martinez-Ripoll, M.]]	+	[[Category: Martinez-Ripoll, M]]
-	[[Category: Yunta, C.]]	+	[[Category: Yunta, C]]
	[[Category: Kinase regulation]]		[[Category: Kinase regulation]]
	[[Category: Plant abiotic stress]]		[[Category: Plant abiotic stress]]
	[[Category: Signaling]]		[[Category: Signaling]]
	[[Category: Transferase]]		[[Category: Transferase]]

OCA at 08:04, 5 June 2014

OCA — Thu, 05 Jun 2014 08:04:55 GMT

←Older revision		Revision as of 08:04, 5 June 2014
Line 1:		Line 1:
-	[[~~Image:~~3zut.~~png~~\|~~left~~\|~~200px~~]]	+	==THE STRUCTURE OF OST1 (D160A) KINASE==
		+	<StructureSection load='3zut' size='340' side='right' caption='[[3zut]], [[Resolution\|resolution]] 2.50Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[3zut]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZUT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ZUT FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3zuu\|3zuu]]</td></tr>
		+	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3zut FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zut OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3zut RCSB], [http://www.ebi.ac.uk/pdbsum/3zut PDBsum]</span></td></tr>
		+	<table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	SnRK [SNF1 (sucrose non-fermenting-1)-related protein kinase] 2.6 [open stomata 1 (OST1)] is well characterized at molecular and physiological levels to control stomata closure in response to water-deficit stress. OST1 is a member of a family of 10 protein kinases from Arabidopsis thaliana (SnRK2) that integrates abscisic acid (ABA)-dependent and ABA-independent signals to coordinate the cell response to osmotic stress. A subgroup of protein phosphatases type 2C binds OST1 and keeps the kinase dephosphorylated and inactive. Activation of OST1 relies on the ABA-dependent inhibition of the protein phosphatases type 2C and the subsequent self-phosphorylation of the kinase. The OST1 ABA-independent activation depends on a short sequence motif that is conserved among all the members of the SnRK2 family. However, little is known about the molecular mechanism underlying this regulation. The crystallographic structure of OST1 shows that ABA-independent regulation motif stabilizes the conformation of the kinase catalytically essential alpha C helix, and it provides the basis of the ABA-independent regulation mechanism for the SnRK2 family of protein kinases.

-	~~<!--~~	+	The Structure of Arabidopsis thaliana OST1 Provides Insights into the Kinase Regulation Mechanism in Response to Osmotic Stress.,Yunta C, Martinez-Ripoll M, Zhu JK, Albert A J Mol Biol. 2011 Nov 18;414(1):135-44. Epub 2011 Oct 1. PMID:21983340<ref>PMID:21983340</ref>
-	The ~~line below this paragraph, containing "STRUCTURE_3zut", creates the "~~Structure ~~Box" on~~ the ~~page~~.	+
-	~~You may change the PDB parameter~~ (~~which sets the PDB file loaded into the applet~~)	+
-	~~or the SCENE parameter (which sets the initial scene displayed when the page is loaded),~~	+
-	~~or leave the SCENE parameter empty for the default display~~.	+
-	-->	+
-	~~{{STRUCTURE_3zut\| PDB=3zut \| SCENE= }}~~	+

-	~~===THE STRUCTURE OF OST1 (D160A) KINASE===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>

-		+	==See Also==
-	~~<!--~~	+	*[[ABA-regulated SNRK2 Protein Kinase\|ABA-regulated SNRK2 Protein Kinase]]
-	~~The line below this paragraph, {{ABSTRACT_PUBMED_21983340}}, adds the Publication Abstract to the page~~	+	*[[Serine/threonine protein kinase\|Serine/threonine protein kinase]]
-	~~(as it appears on PubMed at http://www.pubmed.gov), where 21983340 is the PubMed ID number.~~	+	== References ==
-	~~-->~~	+	<references/>
-	~~{{ABSTRACT_PUBMED_21983340}}~~	+	__TOC__
-		+	</StructureSection>
-	==~~About this Structure~~==	+
-	[[~~3zut~~]] ~~is a 2 chain structure with sequence from~~ [~~http://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from~~ [~~http:~~//~~oca.weizmann.ac.il/oca-bin/ocashort?id=3ZUT OCA~~].	+
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:021983340<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Arabidopsis thaliana]]		[[Category: Arabidopsis thaliana]]
	[[Category: Non-specific serine/threonine protein kinase]]		[[Category: Non-specific serine/threonine protein kinase]]

OCA at 18:07, 23 November 2011

OCA — Wed, 23 Nov 2011 18:07:26 GMT

←Older revision		Revision as of 18:07, 23 November 2011
Line 11:		Line 11:
	===THE STRUCTURE OF OST1 (D160A) KINASE===		===THE STRUCTURE OF OST1 (D160A) KINASE===

		+
		+	<!--
		+	The line below this paragraph, {{ABSTRACT_PUBMED_21983340}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 21983340 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_21983340}}

	==About this Structure==		==About this Structure==
	[[3zut]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZUT OCA].		[[3zut]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZUT OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:021983340</ref><references group="xtra"/>
	[[Category: Arabidopsis thaliana]]		[[Category: Arabidopsis thaliana]]
	[[Category: Non-specific serine/threonine protein kinase]]		[[Category: Non-specific serine/threonine protein kinase]]

OCA at 09:55, 30 October 2011

OCA — Sun, 30 Oct 2011 09:55:25 GMT

←Older revision		Revision as of 09:55, 30 October 2011
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	[[Image:3zut.png\|left\|200px]]

-	The ~~entry 3zut~~ is ~~ON HOLD~~ ~~until Paper Publication~~	+	<!--
		+	The line below this paragraph, containing "STRUCTURE_3zut", creates the "Structure Box" on the page.
		+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
		+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
		+	or leave the SCENE parameter empty for the default display.
		+	-->
		+	{{STRUCTURE_3zut\| PDB=3zut \| SCENE= }}

-	~~Authors: Yunta, C., Martinez-Ripoll, M., Albert, A.~~	+	===THE STRUCTURE OF OST1 (D160A) KINASE===

-	~~Description: The~~ structure ~~of OST1 (D160A)~~ kinase	+
		+	==About this Structure==
		+	[[3zut]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZUT OCA].
		+	[[Category: Arabidopsis thaliana]]
		+	[[Category: Non-specific serine/threonine protein kinase]]
		+	[[Category: Albert, A.]]
		+	[[Category: Martinez-Ripoll, M.]]
		+	[[Category: Yunta, C.]]
		+	[[Category: Kinase regulation]]
		+	[[Category: Plant abiotic stress]]
		+	[[Category: Signaling]]
		+	[[Category: Transferase]]

OCA: Protected "3zut" [edit=sysop:move=sysop]

OCA — Wed, 27 Jul 2011 05:49:22 GMT

Protected "3zut" [edit=sysop:move=sysop]

←Older revision

Revision as of 05:49, 27 July 2011

OCA: New page: '''Unreleased structure''' The entry 3zut is ON HOLD until Paper Publication Authors: Yunta, C., Martinez-Ripoll, M., Albert, A. Description: The structure of OST1 (D160A) kinase

OCA — Wed, 27 Jul 2011 05:49:21 GMT

New page: '''Unreleased structure''' The entry 3zut is ON HOLD until Paper Publication Authors: Yunta, C., Martinez-Ripoll, M., Albert, A. Description: The structure of OST1 (D160A) kinase

New page

'''Unreleased structure'''

The entry 3zut is ON HOLD until Paper Publication

Authors: Yunta, C., Martinez-Ripoll, M., Albert, A.

Description: The structure of OST1 (D160A) kinase