4abj - Revision history

OCA at 09:10, 15 November 2023

OCA — Wed, 15 Nov 2023 09:10:06 GMT

←Older revision		Revision as of 09:10, 15 November 2023
Line 3:		Line 3:
	<StructureSection load='4abj' size='340' side='right'caption='[[4abj]], [[Resolution\|resolution]] 1.45Å' scene=''>		<StructureSection load='4abj' size='340' side='right'caption='[[4abj]], [[Resolution\|resolution]] 1.45Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4abj]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ABJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4ABJ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4abj]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus] and [https://en.wikipedia.org/wiki/Helianthus_annuus Helianthus annuus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ABJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4ABJ FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=DMF:DIMETHYLFORMAMIDE'>DMF</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, ~~<scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.45Å</td></tr>
-	~~<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat">~~<scene name='pdbligand=PLW:(2S)-2-[5-(1S,2S)-(1-AMINO-2-METHYL-BUTYL)-[1,2,3]TRIAZOL-1-YL]-PROPIONIC+ACID'>PLW</scene>~~</td></tr>~~	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=DMF:DIMETHYLFORMAMIDE'>DMF</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PLW:(2S)-2-[5-(1S,2S)-(1-AMINO-2-METHYL-BUTYL)-[1,2,3]TRIAZOL-1-YL]-PROPIONIC+ACID'>PLW</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[5ptp\|5ptp]]~~, [[1o2s\|1o2s]], [[1o2t\|1o2t]], [[1bjv\|1bjv]], [[1c2d\|1c2d]], [[1c2e\|1c2e]], [[1mts\|1mts]], [[1tps\|1tps]], [[1tng\|1tng]], [[1o2m\|1o2m]], [[1c1p\|1c1p]], [[1jrt\|1jrt]], [[2btc\|2btc]], [[1c1t\|1c1t]], [[1tnk\|1tnk]], [[1o2x\|1o2x]], [[1d6r\|1d6r]], [[1c2h\|1c2h]], [[1o38\|1o38]], [[1utp\|1utp]], [[1f2s\|1f2s]], [[1gi1\|1gi1]], [[1tio\|1tio]], [[1v2k\|1v2k]], [[1tpo\|1tpo]], [[2blw\|2blw]], [[1v2o\|1v2o]], [[2fx6\|2fx6]], [[1c1n\|1c1n]], [[1y3u\|1y3u]], [[1y3x\|1y3x]], [[1c5p\|1c5p]], [[1o2i\|1o2i]], [[1c2j\|1c2j]], [[1n6x\|1n6x]], [[1c5u\|1c5u]], [[1o3m\|1o3m]], [[1k1o\|1k1o]], [[1v2v\|1v2v]], [[1ghz\|1ghz]], [[1y5u\|1y5u]], [[2fi3\|2fi3]], [[1qb1\|1qb1]], [[2ptc\|2ptc]], [[1k1l\|1k1l]], [[2tgd\|2tgd]], [[1y5b\|1y5b]], [[1c5t\|1c5t]], [[1p2j\|1p2j]], [[1smf\|1smf]], [[1btp\|1btp]], [[1ppe\|1ppe]], [[2ayw\|2ayw]], [[1btx\|1btx]], [[2by8\|2by8]], [[1gi6\|1gi6]], [[1cu8\|1cu8]], [[1c5q\|1c5q]], [[1ntp\|1ntp]], [[1qb9\|1qb9]], [[1g3e\|1g3e]], [[1o35\|1o35]], [[3btk\|3btk]], [[1ejm\|1ejm]], [[3ptn\|3ptn]], [[1uto\|1uto]], [[1o3h\|1o3h]], [[2fi4\|2fi4]], [[1o3i\|1o3i]], [[1y3y\|1y3y]], [[1o2k\|1o2k]], [[1ppc\|1ppc]], [[1o3d\|1o3d]], [[1o2y\|1o2y]], [[1j8a\|1j8a]], [[1c1q\|1c1q]], [[1o2l\|1o2l]], [[1y59\|1y59]], [[2tgt\|2tgt]], [[3btm\|3btm]], [[1v2s\|1v2s]], [[1o2o\|1o2o]], [[1xui\|1xui]], [[1ql8\|1ql8]], [[3btf\|3btf]], [[1s0q\|1s0q]], [[1o2w\|1o2w]], [[1bju\|1bju]], [[1qb6\|1qb6]], [[1o39\|1o39]], [[1gi5\|1gi5]], [[1tab\|1tab]], [[1gi2\|1gi2]], [[1g3d\|1g3d]], [[1cu7\|1cu7]], [[1tpa\|1tpa]], [[1o2h\|1o2h]], [[2ftl\|2ftl]], [[1mtv\|1mtv]], [[1v2r\|1v2r]], [[1o3l\|1o3l]], [[1o2r\|1o2r]], [[1tx8\|1tx8]], [[1v2j\|1v2j]], [[3bth\|3bth]], [[1o3c\|1o3c]], [[1c2i\|1c2i]], [[1o3k\|1o3k]], [[1ezx\|1ezx]], [[1k1m\|1k1m]], [[1utn\|1utn]], [[1ce5\|1ce5]], [[2by7\|2by7]], [[1o32\|1o32]], [[1k1i\|1k1i]], [[1yp9\|1yp9]], [[1max\|1max]], [[1tgc\|1tgc]], [[1oph\|1oph]], [[3bte\|3bte]], [[1v2n\|1v2n]], [[3tpi\|3tpi]], [[1eb2\|1eb2]], [[2tio\|2tio]], [[2tld\|2tld]], [[1bty\|1bty]], [[2ptn\|2ptn]], [[2fi5\|2fi5]], [[1v2t\|1v2t]], [[2tga\|2tga]], [[1c2l\|1c2l]], [[1o2v\|1o2v]], [[1o36\|1o36]], [[2cmy\|2cmy]], [[1f0u\|1f0u]], [[1o33\|1o33]], [[1tgt\|1tgt]], [[2by6\|2by6]], [[1c2f\|1c2f]], [[3btq\|3btq]], [[1az8\|1az8]], [[1tgb\|1tgb]], [[1qcp\|1qcp]], [[1o3e\|1o3e]], [[3btt\|3btt]], [[1o3o\|1o3o]], [[1p2i\|1p2i]], [[1tx7\|1tx7]], [[1c2m\|1c2m]], [[1o30\|1o30]], [[1o2z\|1o2z]], [[1sbw\|1sbw]], [[1y5a\|1y5a]], [[1aq7\|1aq7]], [[1s0r\|1s0r]], [[1qbo\|1qbo]], [[1oyq\|1oyq]], [[1btw\|1btw]], [[1xuj\|1xuj]], [[1utq\|1utq]], [[1v2q\|1v2q]], [[1mtu\|1mtu]], [[1tgn\|1tgn]], [[1k1p\|1k1p]], [[1k1j\|1k1j]], [[1gi3\|1gi3]], [[1tpp\|1tpp]], [[1o2q\|1o2q]], [[1o3a\|1o3a]], [[1c9t\|1c9t]], [[1g9i\|1g9i]], [[1hj9\|1hj9]], [[1gi4\|1gi4]], [[1ox1\|1ox1]], [[2ftm\|2ftm]], [[2xtt\|2xtt]], [[1v2w\|1v2w]], [[2blv\|2blv]], [[1ql7\|1ql7]], [[1g3b\|1g3b]], [[1tld\|1tld]], [[1mtw\|1mtw]], [[1qa0\|1qa0]], [[1lqe\|1lqe]], [[1o3f\|1o3f]], [[1tnh\|1tnh]], [[1xug\|1xug]], [[1o3b\|1o3b]], [[1o3j\|1o3j]], [[1rxp\|1rxp]], [[1c1r\|1c1r]], [[1tni\|1tni]], [[1btz\|1btz]], [[1y3v\|1y3v]], [[3btw\|3btw]], [[1v2m\|1v2m]], [[1nc6\|1nc6]], [[1o2u\|1o2u]], [[1yyy\|1yyy]], [[1c2g\|1c2g]], [[3btd\|3btd]], [[1c1s\|1c1s]], [[1taw\|1taw]], [[1zzz\|1zzz]], [[2tgp\|2tgp]], [[1jrs\|1jrs]], [[1tnl\|1tnl]], [[2fx4\|2fx4]], [[1c1o\|1c1o]], [[1f0t\|1f0t]], [[1n6y\|1n6y]], [[1zr0\|1zr0]], [[1k1n\|1k1n]], [[1v2u\|1v2u]], [[1jir\|1jir]], [[1may\|1may]], [[2ah4\|2ah4]], [[2by5\|2by5]], [[1xuk\|1xuk]], [[1gi0\|1gi0]], [[2uuy\|2uuy]], [[1tyn\|1tyn]], [[1tgs\|1tgs]], [[1o31\|1o31]], [[1v2p\|1v2p]], [[2a7h\|2a7h]], [[2tpi\|2tpi]], [[1o37\|1o37]], [[1qbn\|1qbn]], [[2bya\|2bya]], [[1v2l\|1v2l]], [[1o2j\|1o2j]], [[4tpi\|4tpi]], [[1sfi\|1sfi]], [[1p2k\|1p2k]], [[1o34\|1o34]], [[1g36\|1g36]], [[1xuh\|1xuh]], [[2bza\|2bza]], [[1c5v\|1c5v]], [[1gbt\|1gbt]], [[1g3c\|1g3c]], [[3btg\|3btg]], [[1pph\|1pph]], [[1cu9\|1cu9]], [[3ptb\|3ptb]], [[1o3n\|1o3n]], [[1o3g\|1o3g]], [[1c5r\|1c5r]], [[1c5s\|1c5s]], [[1xuf\|1xuf]], [[1tnj\|1tnj]], [[2by9\|2by9]], [[1o2n\|1o2n]], [[1c2k\|1c2k]], [[1gj6\|1gj6]], [[1y3w\|1y3w]], [[1auj\|1auj]], [[1o2p\|1o2p]], [[2j9n\|2j9n]], [[4abi\|4abi]]<~~/div></td></tr>~~	+
-	~~<tr id~~='~~activity'><td class~~=~~"sblockLbl"><b>Activity~~:~~</b></td><td class="sblockDat"><span class='plainlinks~~'>~~[https://en.wikipedia.org/wiki/Trypsin Trypsin], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.4 3.4.21.4]~~ </~~span~~></td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4abj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4abj OCA], [https://pdbe.org/4abj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4abj RCSB], [https://www.ebi.ac.uk/pdbsum/4abj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4abj ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4abj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4abj OCA], [https://pdbe.org/4abj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4abj RCSB], [https://www.ebi.ac.uk/pdbsum/4abj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4abj ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/~~SFTI1_HELAN SFTI1_HELAN~~]~~] Inhibits trypsin, cathepsin G, elastase, chymotrypsin and thrombin. Does not inhibit factor Xa.<ref>PMID:10390350</ref>~~	+	[https://www.uniprot.org/uniprot/TRY1_BOVIN TRY1_BOVIN]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 30:		Line 28:
	</StructureSection>		</StructureSection>
	[[Category: Bos taurus]]		[[Category: Bos taurus]]
		+	[[Category: Helianthus annuus]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	~~[[Category: Trypsin]]~~	+	[[Category: Empting M]]
-	[[Category: Empting, M]]	+	[[Category: Heinz D]]
-	[[Category: Heinz, D]]	+	[[Category: Kolmar H]]
-	[[Category: Kolmar, H]]	+	[[Category: Nasu D]]
-	[[Category: Nasu, D]]	+	[[Category: Schmelz S]]
-	[[Category: Schmelz, S]]	+	[[Category: Tischler M]]
-	[[Category: Tischler, M]]	+
-	~~[[Category: Amide mimic]]~~	+
-	~~[[Category: Hydrolase-inhibitor complex~~]]	+

OCA at 05:28, 25 August 2022

OCA — Thu, 25 Aug 2022 05:28:25 GMT

OCA at 05:09, 19 November 2020

OCA — Thu, 19 Nov 2020 05:09:05 GMT

←Older revision		Revision as of 05:09, 19 November 2020
Line 3:		Line 3:
	<StructureSection load='4abj' size='340' side='right'caption='[[4abj]], [[Resolution\|resolution]] 1.45Å' scene=''>		<StructureSection load='4abj' size='340' side='right'caption='[[4abj]], [[Resolution\|resolution]] 1.45Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4abj]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ABJ OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4ABJ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4abj]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ABJ OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=4ABJ FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=DMF:DIMETHYLFORMAMIDE'>DMF</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=DMF:DIMETHYLFORMAMIDE'>DMF</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=PLW:(2S)-2-[5-(1S,2S)-(1-AMINO-2-METHYL-BUTYL)-[1,2,3]TRIAZOL-1-YL]-PROPIONIC+ACID'>PLW</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=PLW:(2S)-2-[5-(1S,2S)-(1-AMINO-2-METHYL-BUTYL)-[1,2,3]TRIAZOL-1-YL]-PROPIONIC+ACID'>PLW</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5ptp\|5ptp]], [[1o2s\|1o2s]], [[1o2t\|1o2t]], [[1bjv\|1bjv]], [[1c2d\|1c2d]], [[1c2e\|1c2e]], [[1mts\|1mts]], [[1tps\|1tps]], [[1tng\|1tng]], [[1o2m\|1o2m]], [[1c1p\|1c1p]], [[1jrt\|1jrt]], [[2btc\|2btc]], [[1c1t\|1c1t]], [[1tnk\|1tnk]], [[1o2x\|1o2x]], [[1d6r\|1d6r]], [[1c2h\|1c2h]], [[1o38\|1o38]], [[1utp\|1utp]], [[1f2s\|1f2s]], [[1gi1\|1gi1]], [[1tio\|1tio]], [[1v2k\|1v2k]], [[1tpo\|1tpo]], [[2blw\|2blw]], [[1v2o\|1v2o]], [[2fx6\|2fx6]], [[1c1n\|1c1n]], [[1y3u\|1y3u]], [[1y3x\|1y3x]], [[1c5p\|1c5p]], [[1o2i\|1o2i]], [[1c2j\|1c2j]], [[1n6x\|1n6x]], [[1c5u\|1c5u]], [[1o3m\|1o3m]], [[1k1o\|1k1o]], [[1v2v\|1v2v]], [[1ghz\|1ghz]], [[1y5u\|1y5u]], [[2fi3\|2fi3]], [[1qb1\|1qb1]], [[2ptc\|2ptc]], [[1k1l\|1k1l]], [[2tgd\|2tgd]], [[1y5b\|1y5b]], [[1c5t\|1c5t]], [[1p2j\|1p2j]], [[1smf\|1smf]], [[1btp\|1btp]], [[1ppe\|1ppe]], [[2ayw\|2ayw]], [[1btx\|1btx]], [[2by8\|2by8]], [[1gi6\|1gi6]], [[1cu8\|1cu8]], [[1c5q\|1c5q]], [[1ntp\|1ntp]], [[1qb9\|1qb9]], [[1g3e\|1g3e]], [[1o35\|1o35]], [[3btk\|3btk]], [[1ejm\|1ejm]], [[3ptn\|3ptn]], [[1uto\|1uto]], [[1o3h\|1o3h]], [[2fi4\|2fi4]], [[1o3i\|1o3i]], [[1y3y\|1y3y]], [[1o2k\|1o2k]], [[1ppc\|1ppc]], [[1o3d\|1o3d]], [[1o2y\|1o2y]], [[1j8a\|1j8a]], [[1c1q\|1c1q]], [[1o2l\|1o2l]], [[1y59\|1y59]], [[2tgt\|2tgt]], [[3btm\|3btm]], [[1v2s\|1v2s]], [[1o2o\|1o2o]], [[1xui\|1xui]], [[1ql8\|1ql8]], [[3btf\|3btf]], [[1s0q\|1s0q]], [[1o2w\|1o2w]], [[1bju\|1bju]], [[1qb6\|1qb6]], [[1o39\|1o39]], [[1gi5\|1gi5]], [[1tab\|1tab]], [[1gi2\|1gi2]], [[1g3d\|1g3d]], [[1cu7\|1cu7]], [[1tpa\|1tpa]], [[1o2h\|1o2h]], [[2ftl\|2ftl]], [[1mtv\|1mtv]], [[1v2r\|1v2r]], [[1o3l\|1o3l]], [[1o2r\|1o2r]], [[1tx8\|1tx8]], [[1v2j\|1v2j]], [[3bth\|3bth]], [[1o3c\|1o3c]], [[1c2i\|1c2i]], [[1o3k\|1o3k]], [[1ezx\|1ezx]], [[1k1m\|1k1m]], [[1utn\|1utn]], [[1ce5\|1ce5]], [[2by7\|2by7]], [[1o32\|1o32]], [[1k1i\|1k1i]], [[1yp9\|1yp9]], [[1max\|1max]], [[1tgc\|1tgc]], [[1oph\|1oph]], [[3bte\|3bte]], [[1v2n\|1v2n]], [[3tpi\|3tpi]], [[1eb2\|1eb2]], [[2tio\|2tio]], [[2tld\|2tld]], [[1bty\|1bty]], [[2ptn\|2ptn]], [[2fi5\|2fi5]], [[1v2t\|1v2t]], [[2tga\|2tga]], [[1c2l\|1c2l]], [[1o2v\|1o2v]], [[1o36\|1o36]], [[2cmy\|2cmy]], [[1f0u\|1f0u]], [[1o33\|1o33]], [[1tgt\|1tgt]], [[2by6\|2by6]], [[1c2f\|1c2f]], [[3btq\|3btq]], [[1az8\|1az8]], [[1tgb\|1tgb]], [[1qcp\|1qcp]], [[1o3e\|1o3e]], [[3btt\|3btt]], [[1o3o\|1o3o]], [[1p2i\|1p2i]], [[1tx7\|1tx7]], [[1c2m\|1c2m]], [[1o30\|1o30]], [[1o2z\|1o2z]], [[1sbw\|1sbw]], [[1y5a\|1y5a]], [[1aq7\|1aq7]], [[1s0r\|1s0r]], [[1qbo\|1qbo]], [[1oyq\|1oyq]], [[1btw\|1btw]], [[1xuj\|1xuj]], [[1utq\|1utq]], [[1v2q\|1v2q]], [[1mtu\|1mtu]], [[1tgn\|1tgn]], [[1k1p\|1k1p]], [[1k1j\|1k1j]], [[1gi3\|1gi3]], [[1tpp\|1tpp]], [[1o2q\|1o2q]], [[1o3a\|1o3a]], [[1c9t\|1c9t]], [[1g9i\|1g9i]], [[1hj9\|1hj9]], [[1gi4\|1gi4]], [[1ox1\|1ox1]], [[2ftm\|2ftm]], [[2xtt\|2xtt]], [[1v2w\|1v2w]], [[2blv\|2blv]], [[1ql7\|1ql7]], [[1g3b\|1g3b]], [[1tld\|1tld]], [[1mtw\|1mtw]], [[1qa0\|1qa0]], [[1lqe\|1lqe]], [[1o3f\|1o3f]], [[1tnh\|1tnh]], [[1xug\|1xug]], [[1o3b\|1o3b]], [[1o3j\|1o3j]], [[1rxp\|1rxp]], [[1c1r\|1c1r]], [[1tni\|1tni]], [[1btz\|1btz]], [[1y3v\|1y3v]], [[3btw\|3btw]], [[1v2m\|1v2m]], [[1nc6\|1nc6]], [[1o2u\|1o2u]], [[1yyy\|1yyy]], [[1c2g\|1c2g]], [[3btd\|3btd]], [[1c1s\|1c1s]], [[1taw\|1taw]], [[1zzz\|1zzz]], [[2tgp\|2tgp]], [[1jrs\|1jrs]], [[1tnl\|1tnl]], [[2fx4\|2fx4]], [[1c1o\|1c1o]], [[1f0t\|1f0t]], [[1n6y\|1n6y]], [[1zr0\|1zr0]], [[1k1n\|1k1n]], [[1v2u\|1v2u]], [[1jir\|1jir]], [[1may\|1may]], [[2ah4\|2ah4]], [[2by5\|2by5]], [[1xuk\|1xuk]], [[1gi0\|1gi0]], [[2uuy\|2uuy]], [[1tyn\|1tyn]], [[1tgs\|1tgs]], [[1o31\|1o31]], [[1v2p\|1v2p]], [[2a7h\|2a7h]], [[2tpi\|2tpi]], [[1o37\|1o37]], [[1qbn\|1qbn]], [[2bya\|2bya]], [[1v2l\|1v2l]], [[1o2j\|1o2j]], [[4tpi\|4tpi]], [[1sfi\|1sfi]], [[1p2k\|1p2k]], [[1o34\|1o34]], [[1g36\|1g36]], [[1xuh\|1xuh]], [[2bza\|2bza]], [[1c5v\|1c5v]], [[1gbt\|1gbt]], [[1g3c\|1g3c]], [[3btg\|3btg]], [[1pph\|1pph]], [[1cu9\|1cu9]], [[3ptb\|3ptb]], [[1o3n\|1o3n]], [[1o3g\|1o3g]], [[1c5r\|1c5r]], [[1c5s\|1c5s]], [[1xuf\|1xuf]], [[1tnj\|1tnj]], [[2by9\|2by9]], [[1o2n\|1o2n]], [[1c2k\|1c2k]], [[1gj6\|1gj6]], [[1y3w\|1y3w]], [[1auj\|1auj]], [[1o2p\|1o2p]], [[2j9n\|2j9n]], [[4abi\|4abi]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[5ptp\|5ptp]], [[1o2s\|1o2s]], [[1o2t\|1o2t]], [[1bjv\|1bjv]], [[1c2d\|1c2d]], [[1c2e\|1c2e]], [[1mts\|1mts]], [[1tps\|1tps]], [[1tng\|1tng]], [[1o2m\|1o2m]], [[1c1p\|1c1p]], [[1jrt\|1jrt]], [[2btc\|2btc]], [[1c1t\|1c1t]], [[1tnk\|1tnk]], [[1o2x\|1o2x]], [[1d6r\|1d6r]], [[1c2h\|1c2h]], [[1o38\|1o38]], [[1utp\|1utp]], [[1f2s\|1f2s]], [[1gi1\|1gi1]], [[1tio\|1tio]], [[1v2k\|1v2k]], [[1tpo\|1tpo]], [[2blw\|2blw]], [[1v2o\|1v2o]], [[2fx6\|2fx6]], [[1c1n\|1c1n]], [[1y3u\|1y3u]], [[1y3x\|1y3x]], [[1c5p\|1c5p]], [[1o2i\|1o2i]], [[1c2j\|1c2j]], [[1n6x\|1n6x]], [[1c5u\|1c5u]], [[1o3m\|1o3m]], [[1k1o\|1k1o]], [[1v2v\|1v2v]], [[1ghz\|1ghz]], [[1y5u\|1y5u]], [[2fi3\|2fi3]], [[1qb1\|1qb1]], [[2ptc\|2ptc]], [[1k1l\|1k1l]], [[2tgd\|2tgd]], [[1y5b\|1y5b]], [[1c5t\|1c5t]], [[1p2j\|1p2j]], [[1smf\|1smf]], [[1btp\|1btp]], [[1ppe\|1ppe]], [[2ayw\|2ayw]], [[1btx\|1btx]], [[2by8\|2by8]], [[1gi6\|1gi6]], [[1cu8\|1cu8]], [[1c5q\|1c5q]], [[1ntp\|1ntp]], [[1qb9\|1qb9]], [[1g3e\|1g3e]], [[1o35\|1o35]], [[3btk\|3btk]], [[1ejm\|1ejm]], [[3ptn\|3ptn]], [[1uto\|1uto]], [[1o3h\|1o3h]], [[2fi4\|2fi4]], [[1o3i\|1o3i]], [[1y3y\|1y3y]], [[1o2k\|1o2k]], [[1ppc\|1ppc]], [[1o3d\|1o3d]], [[1o2y\|1o2y]], [[1j8a\|1j8a]], [[1c1q\|1c1q]], [[1o2l\|1o2l]], [[1y59\|1y59]], [[2tgt\|2tgt]], [[3btm\|3btm]], [[1v2s\|1v2s]], [[1o2o\|1o2o]], [[1xui\|1xui]], [[1ql8\|1ql8]], [[3btf\|3btf]], [[1s0q\|1s0q]], [[1o2w\|1o2w]], [[1bju\|1bju]], [[1qb6\|1qb6]], [[1o39\|1o39]], [[1gi5\|1gi5]], [[1tab\|1tab]], [[1gi2\|1gi2]], [[1g3d\|1g3d]], [[1cu7\|1cu7]], [[1tpa\|1tpa]], [[1o2h\|1o2h]], [[2ftl\|2ftl]], [[1mtv\|1mtv]], [[1v2r\|1v2r]], [[1o3l\|1o3l]], [[1o2r\|1o2r]], [[1tx8\|1tx8]], [[1v2j\|1v2j]], [[3bth\|3bth]], [[1o3c\|1o3c]], [[1c2i\|1c2i]], [[1o3k\|1o3k]], [[1ezx\|1ezx]], [[1k1m\|1k1m]], [[1utn\|1utn]], [[1ce5\|1ce5]], [[2by7\|2by7]], [[1o32\|1o32]], [[1k1i\|1k1i]], [[1yp9\|1yp9]], [[1max\|1max]], [[1tgc\|1tgc]], [[1oph\|1oph]], [[3bte\|3bte]], [[1v2n\|1v2n]], [[3tpi\|3tpi]], [[1eb2\|1eb2]], [[2tio\|2tio]], [[2tld\|2tld]], [[1bty\|1bty]], [[2ptn\|2ptn]], [[2fi5\|2fi5]], [[1v2t\|1v2t]], [[2tga\|2tga]], [[1c2l\|1c2l]], [[1o2v\|1o2v]], [[1o36\|1o36]], [[2cmy\|2cmy]], [[1f0u\|1f0u]], [[1o33\|1o33]], [[1tgt\|1tgt]], [[2by6\|2by6]], [[1c2f\|1c2f]], [[3btq\|3btq]], [[1az8\|1az8]], [[1tgb\|1tgb]], [[1qcp\|1qcp]], [[1o3e\|1o3e]], [[3btt\|3btt]], [[1o3o\|1o3o]], [[1p2i\|1p2i]], [[1tx7\|1tx7]], [[1c2m\|1c2m]], [[1o30\|1o30]], [[1o2z\|1o2z]], [[1sbw\|1sbw]], [[1y5a\|1y5a]], [[1aq7\|1aq7]], [[1s0r\|1s0r]], [[1qbo\|1qbo]], [[1oyq\|1oyq]], [[1btw\|1btw]], [[1xuj\|1xuj]], [[1utq\|1utq]], [[1v2q\|1v2q]], [[1mtu\|1mtu]], [[1tgn\|1tgn]], [[1k1p\|1k1p]], [[1k1j\|1k1j]], [[1gi3\|1gi3]], [[1tpp\|1tpp]], [[1o2q\|1o2q]], [[1o3a\|1o3a]], [[1c9t\|1c9t]], [[1g9i\|1g9i]], [[1hj9\|1hj9]], [[1gi4\|1gi4]], [[1ox1\|1ox1]], [[2ftm\|2ftm]], [[2xtt\|2xtt]], [[1v2w\|1v2w]], [[2blv\|2blv]], [[1ql7\|1ql7]], [[1g3b\|1g3b]], [[1tld\|1tld]], [[1mtw\|1mtw]], [[1qa0\|1qa0]], [[1lqe\|1lqe]], [[1o3f\|1o3f]], [[1tnh\|1tnh]], [[1xug\|1xug]], [[1o3b\|1o3b]], [[1o3j\|1o3j]], [[1rxp\|1rxp]], [[1c1r\|1c1r]], [[1tni\|1tni]], [[1btz\|1btz]], [[1y3v\|1y3v]], [[3btw\|3btw]], [[1v2m\|1v2m]], [[1nc6\|1nc6]], [[1o2u\|1o2u]], [[1yyy\|1yyy]], [[1c2g\|1c2g]], [[3btd\|3btd]], [[1c1s\|1c1s]], [[1taw\|1taw]], [[1zzz\|1zzz]], [[2tgp\|2tgp]], [[1jrs\|1jrs]], [[1tnl\|1tnl]], [[2fx4\|2fx4]], [[1c1o\|1c1o]], [[1f0t\|1f0t]], [[1n6y\|1n6y]], [[1zr0\|1zr0]], [[1k1n\|1k1n]], [[1v2u\|1v2u]], [[1jir\|1jir]], [[1may\|1may]], [[2ah4\|2ah4]], [[2by5\|2by5]], [[1xuk\|1xuk]], [[1gi0\|1gi0]], [[2uuy\|2uuy]], [[1tyn\|1tyn]], [[1tgs\|1tgs]], [[1o31\|1o31]], [[1v2p\|1v2p]], [[2a7h\|2a7h]], [[2tpi\|2tpi]], [[1o37\|1o37]], [[1qbn\|1qbn]], [[2bya\|2bya]], [[1v2l\|1v2l]], [[1o2j\|1o2j]], [[4tpi\|4tpi]], [[1sfi\|1sfi]], [[1p2k\|1p2k]], [[1o34\|1o34]], [[1g36\|1g36]], [[1xuh\|1xuh]], [[2bza\|2bza]], [[1c5v\|1c5v]], [[1gbt\|1gbt]], [[1g3c\|1g3c]], [[3btg\|3btg]], [[1pph\|1pph]], [[1cu9\|1cu9]], [[3ptb\|3ptb]], [[1o3n\|1o3n]], [[1o3g\|1o3g]], [[1c5r\|1c5r]], [[1c5s\|1c5s]], [[1xuf\|1xuf]], [[1tnj\|1tnj]], [[2by9\|2by9]], [[1o2n\|1o2n]], [[1c2k\|1c2k]], [[1gj6\|1gj6]], [[1y3w\|1y3w]], [[1auj\|1auj]], [[1o2p\|1o2p]], [[2j9n\|2j9n]], [[4abi\|4abi]]</div></td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Trypsin Trypsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.4 3.4.21.4] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Trypsin Trypsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.4 3.4.21.4] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4abj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4abj OCA], [http://pdbe.org/4abj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4abj RCSB], [http://www.ebi.ac.uk/pdbsum/4abj PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4abj ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=4abj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4abj OCA], [http://pdbe.org/4abj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4abj RCSB], [http://www.ebi.ac.uk/pdbsum/4abj PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4abj ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 23:		Line 23:

	==See Also==		==See Also==
-	*[[Trypsin\|Trypsin]]	+	*[[Trypsin 3D structures\|Trypsin 3D structures]]
-	*[[Trypsin inhibitor\|Trypsin inhibitor]]	+	*[[Trypsin inhibitor 3D structures\|Trypsin inhibitor 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 30:		Line 30:
	</StructureSection>		</StructureSection>
	[[Category: Bos taurus]]		[[Category: Bos taurus]]
		+	[[Category: Large Structures]]
	[[Category: Trypsin]]		[[Category: Trypsin]]
	[[Category: Empting, M]]		[[Category: Empting, M]]

OCA at 09:05, 6 March 2019

OCA — Wed, 06 Mar 2019 09:05:57 GMT

←Older revision		Revision as of 09:05, 6 March 2019
Line 1:		Line 1:

-	==Co-complex structure of bovine trypsin with a modified Bowman-Birk inhibitor (IcA)SFTI-1(1,14), that was 1,5-disubstituted with 1,2,3- trizol to mimic a cis ~~amid~~ bond==	+	==Co-complex structure of bovine trypsin with a modified Bowman-Birk inhibitor (IcA)SFTI-1(1,14), that was 1,5-disubstituted with 1,2,3- trizol to mimic a cis amide bond==
-	<StructureSection load='4abj' size='340' side='right' caption='[[4abj]], [[Resolution\|resolution]] 1.45Å' scene=''>	+	<StructureSection load='4abj' size='340' side='right'caption='[[4abj]], [[Resolution\|resolution]] 1.45Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4abj]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ABJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ABJ FirstGlance]. <br>		<table><tr><td colspan='2'>[[4abj]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ABJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ABJ FirstGlance]. <br>

OCA at 03:01, 5 August 2016

OCA — Fri, 05 Aug 2016 03:01:39 GMT

←Older revision		Revision as of 03:01, 5 August 2016
Line 1:		Line 1:
		+
	==Co-complex structure of bovine trypsin with a modified Bowman-Birk inhibitor (IcA)SFTI-1(1,14), that was 1,5-disubstituted with 1,2,3- trizol to mimic a cis amid bond==		==Co-complex structure of bovine trypsin with a modified Bowman-Birk inhibitor (IcA)SFTI-1(1,14), that was 1,5-disubstituted with 1,2,3- trizol to mimic a cis amid bond==
	<StructureSection load='4abj' size='340' side='right' caption='[[4abj]], [[Resolution\|resolution]] 1.45Å' scene=''>		<StructureSection load='4abj' size='340' side='right' caption='[[4abj]], [[Resolution\|resolution]] 1.45Å' scene=''>
Line 7:		Line 8:
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5ptp\|5ptp]], [[1o2s\|1o2s]], [[1o2t\|1o2t]], [[1bjv\|1bjv]], [[1c2d\|1c2d]], [[1c2e\|1c2e]], [[1mts\|1mts]], [[1tps\|1tps]], [[1tng\|1tng]], [[1o2m\|1o2m]], [[1c1p\|1c1p]], [[1jrt\|1jrt]], [[2btc\|2btc]], [[1c1t\|1c1t]], [[1tnk\|1tnk]], [[1o2x\|1o2x]], [[1d6r\|1d6r]], [[1c2h\|1c2h]], [[1o38\|1o38]], [[1utp\|1utp]], [[1f2s\|1f2s]], [[1gi1\|1gi1]], [[1tio\|1tio]], [[1v2k\|1v2k]], [[1tpo\|1tpo]], [[2blw\|2blw]], [[1v2o\|1v2o]], [[2fx6\|2fx6]], [[1c1n\|1c1n]], [[1y3u\|1y3u]], [[1y3x\|1y3x]], [[1c5p\|1c5p]], [[1o2i\|1o2i]], [[1c2j\|1c2j]], [[1n6x\|1n6x]], [[1c5u\|1c5u]], [[1o3m\|1o3m]], [[1k1o\|1k1o]], [[1v2v\|1v2v]], [[1ghz\|1ghz]], [[1y5u\|1y5u]], [[2fi3\|2fi3]], [[1qb1\|1qb1]], [[2ptc\|2ptc]], [[1k1l\|1k1l]], [[2tgd\|2tgd]], [[1y5b\|1y5b]], [[1c5t\|1c5t]], [[1p2j\|1p2j]], [[1smf\|1smf]], [[1btp\|1btp]], [[1ppe\|1ppe]], [[2ayw\|2ayw]], [[1btx\|1btx]], [[2by8\|2by8]], [[1gi6\|1gi6]], [[1cu8\|1cu8]], [[1c5q\|1c5q]], [[1ntp\|1ntp]], [[1qb9\|1qb9]], [[1g3e\|1g3e]], [[1o35\|1o35]], [[3btk\|3btk]], [[1ejm\|1ejm]], [[3ptn\|3ptn]], [[1uto\|1uto]], [[1o3h\|1o3h]], [[2fi4\|2fi4]], [[1o3i\|1o3i]], [[1y3y\|1y3y]], [[1o2k\|1o2k]], [[1ppc\|1ppc]], [[1o3d\|1o3d]], [[1o2y\|1o2y]], [[1j8a\|1j8a]], [[1c1q\|1c1q]], [[1o2l\|1o2l]], [[1y59\|1y59]], [[2tgt\|2tgt]], [[3btm\|3btm]], [[1v2s\|1v2s]], [[1o2o\|1o2o]], [[1xui\|1xui]], [[1ql8\|1ql8]], [[3btf\|3btf]], [[1s0q\|1s0q]], [[1o2w\|1o2w]], [[1bju\|1bju]], [[1qb6\|1qb6]], [[1o39\|1o39]], [[1gi5\|1gi5]], [[1tab\|1tab]], [[1gi2\|1gi2]], [[1g3d\|1g3d]], [[1cu7\|1cu7]], [[1tpa\|1tpa]], [[1o2h\|1o2h]], [[2ftl\|2ftl]], [[1mtv\|1mtv]], [[1v2r\|1v2r]], [[1o3l\|1o3l]], [[1o2r\|1o2r]], [[1tx8\|1tx8]], [[1v2j\|1v2j]], [[3bth\|3bth]], [[1o3c\|1o3c]], [[1c2i\|1c2i]], [[1o3k\|1o3k]], [[1ezx\|1ezx]], [[1k1m\|1k1m]], [[1utn\|1utn]], [[1ce5\|1ce5]], [[2by7\|2by7]], [[1o32\|1o32]], [[1k1i\|1k1i]], [[1yp9\|1yp9]], [[1max\|1max]], [[1tgc\|1tgc]], [[1oph\|1oph]], [[3bte\|3bte]], [[1v2n\|1v2n]], [[3tpi\|3tpi]], [[1eb2\|1eb2]], [[2tio\|2tio]], [[2tld\|2tld]], [[1bty\|1bty]], [[2ptn\|2ptn]], [[2fi5\|2fi5]], [[1v2t\|1v2t]], [[2tga\|2tga]], [[1c2l\|1c2l]], [[1o2v\|1o2v]], [[1o36\|1o36]], [[2cmy\|2cmy]], [[1f0u\|1f0u]], [[1o33\|1o33]], [[1tgt\|1tgt]], [[2by6\|2by6]], [[1c2f\|1c2f]], [[3btq\|3btq]], [[1az8\|1az8]], [[1tgb\|1tgb]], [[1qcp\|1qcp]], [[1o3e\|1o3e]], [[3btt\|3btt]], [[1o3o\|1o3o]], [[1p2i\|1p2i]], [[1tx7\|1tx7]], [[1c2m\|1c2m]], [[1o30\|1o30]], [[1o2z\|1o2z]], [[1sbw\|1sbw]], [[1y5a\|1y5a]], [[1aq7\|1aq7]], [[1s0r\|1s0r]], [[1qbo\|1qbo]], [[1oyq\|1oyq]], [[1btw\|1btw]], [[1xuj\|1xuj]], [[1utq\|1utq]], [[1v2q\|1v2q]], [[1mtu\|1mtu]], [[1tgn\|1tgn]], [[1k1p\|1k1p]], [[1k1j\|1k1j]], [[1gi3\|1gi3]], [[1tpp\|1tpp]], [[1o2q\|1o2q]], [[1o3a\|1o3a]], [[1c9t\|1c9t]], [[1g9i\|1g9i]], [[1hj9\|1hj9]], [[1gi4\|1gi4]], [[1ox1\|1ox1]], [[2ftm\|2ftm]], [[2xtt\|2xtt]], [[1v2w\|1v2w]], [[2blv\|2blv]], [[1ql7\|1ql7]], [[1g3b\|1g3b]], [[1tld\|1tld]], [[1mtw\|1mtw]], [[1qa0\|1qa0]], [[1lqe\|1lqe]], [[1o3f\|1o3f]], [[1tnh\|1tnh]], [[1xug\|1xug]], [[1o3b\|1o3b]], [[1o3j\|1o3j]], [[1rxp\|1rxp]], [[1c1r\|1c1r]], [[1tni\|1tni]], [[1btz\|1btz]], [[1y3v\|1y3v]], [[3btw\|3btw]], [[1v2m\|1v2m]], [[1nc6\|1nc6]], [[1o2u\|1o2u]], [[1yyy\|1yyy]], [[1c2g\|1c2g]], [[3btd\|3btd]], [[1c1s\|1c1s]], [[1taw\|1taw]], [[1zzz\|1zzz]], [[2tgp\|2tgp]], [[1jrs\|1jrs]], [[1tnl\|1tnl]], [[2fx4\|2fx4]], [[1c1o\|1c1o]], [[1f0t\|1f0t]], [[1n6y\|1n6y]], [[1zr0\|1zr0]], [[1k1n\|1k1n]], [[1v2u\|1v2u]], [[1jir\|1jir]], [[1may\|1may]], [[2ah4\|2ah4]], [[2by5\|2by5]], [[1xuk\|1xuk]], [[1gi0\|1gi0]], [[2uuy\|2uuy]], [[1tyn\|1tyn]], [[1tgs\|1tgs]], [[1o31\|1o31]], [[1v2p\|1v2p]], [[2a7h\|2a7h]], [[2tpi\|2tpi]], [[1o37\|1o37]], [[1qbn\|1qbn]], [[2bya\|2bya]], [[1v2l\|1v2l]], [[1o2j\|1o2j]], [[4tpi\|4tpi]], [[1sfi\|1sfi]], [[1p2k\|1p2k]], [[1o34\|1o34]], [[1g36\|1g36]], [[1xuh\|1xuh]], [[2bza\|2bza]], [[1c5v\|1c5v]], [[1gbt\|1gbt]], [[1g3c\|1g3c]], [[3btg\|3btg]], [[1pph\|1pph]], [[1cu9\|1cu9]], [[3ptb\|3ptb]], [[1o3n\|1o3n]], [[1o3g\|1o3g]], [[1c5r\|1c5r]], [[1c5s\|1c5s]], [[1xuf\|1xuf]], [[1tnj\|1tnj]], [[2by9\|2by9]], [[1o2n\|1o2n]], [[1c2k\|1c2k]], [[1gj6\|1gj6]], [[1y3w\|1y3w]], [[1auj\|1auj]], [[1o2p\|1o2p]], [[2j9n\|2j9n]], [[4abi\|4abi]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5ptp\|5ptp]], [[1o2s\|1o2s]], [[1o2t\|1o2t]], [[1bjv\|1bjv]], [[1c2d\|1c2d]], [[1c2e\|1c2e]], [[1mts\|1mts]], [[1tps\|1tps]], [[1tng\|1tng]], [[1o2m\|1o2m]], [[1c1p\|1c1p]], [[1jrt\|1jrt]], [[2btc\|2btc]], [[1c1t\|1c1t]], [[1tnk\|1tnk]], [[1o2x\|1o2x]], [[1d6r\|1d6r]], [[1c2h\|1c2h]], [[1o38\|1o38]], [[1utp\|1utp]], [[1f2s\|1f2s]], [[1gi1\|1gi1]], [[1tio\|1tio]], [[1v2k\|1v2k]], [[1tpo\|1tpo]], [[2blw\|2blw]], [[1v2o\|1v2o]], [[2fx6\|2fx6]], [[1c1n\|1c1n]], [[1y3u\|1y3u]], [[1y3x\|1y3x]], [[1c5p\|1c5p]], [[1o2i\|1o2i]], [[1c2j\|1c2j]], [[1n6x\|1n6x]], [[1c5u\|1c5u]], [[1o3m\|1o3m]], [[1k1o\|1k1o]], [[1v2v\|1v2v]], [[1ghz\|1ghz]], [[1y5u\|1y5u]], [[2fi3\|2fi3]], [[1qb1\|1qb1]], [[2ptc\|2ptc]], [[1k1l\|1k1l]], [[2tgd\|2tgd]], [[1y5b\|1y5b]], [[1c5t\|1c5t]], [[1p2j\|1p2j]], [[1smf\|1smf]], [[1btp\|1btp]], [[1ppe\|1ppe]], [[2ayw\|2ayw]], [[1btx\|1btx]], [[2by8\|2by8]], [[1gi6\|1gi6]], [[1cu8\|1cu8]], [[1c5q\|1c5q]], [[1ntp\|1ntp]], [[1qb9\|1qb9]], [[1g3e\|1g3e]], [[1o35\|1o35]], [[3btk\|3btk]], [[1ejm\|1ejm]], [[3ptn\|3ptn]], [[1uto\|1uto]], [[1o3h\|1o3h]], [[2fi4\|2fi4]], [[1o3i\|1o3i]], [[1y3y\|1y3y]], [[1o2k\|1o2k]], [[1ppc\|1ppc]], [[1o3d\|1o3d]], [[1o2y\|1o2y]], [[1j8a\|1j8a]], [[1c1q\|1c1q]], [[1o2l\|1o2l]], [[1y59\|1y59]], [[2tgt\|2tgt]], [[3btm\|3btm]], [[1v2s\|1v2s]], [[1o2o\|1o2o]], [[1xui\|1xui]], [[1ql8\|1ql8]], [[3btf\|3btf]], [[1s0q\|1s0q]], [[1o2w\|1o2w]], [[1bju\|1bju]], [[1qb6\|1qb6]], [[1o39\|1o39]], [[1gi5\|1gi5]], [[1tab\|1tab]], [[1gi2\|1gi2]], [[1g3d\|1g3d]], [[1cu7\|1cu7]], [[1tpa\|1tpa]], [[1o2h\|1o2h]], [[2ftl\|2ftl]], [[1mtv\|1mtv]], [[1v2r\|1v2r]], [[1o3l\|1o3l]], [[1o2r\|1o2r]], [[1tx8\|1tx8]], [[1v2j\|1v2j]], [[3bth\|3bth]], [[1o3c\|1o3c]], [[1c2i\|1c2i]], [[1o3k\|1o3k]], [[1ezx\|1ezx]], [[1k1m\|1k1m]], [[1utn\|1utn]], [[1ce5\|1ce5]], [[2by7\|2by7]], [[1o32\|1o32]], [[1k1i\|1k1i]], [[1yp9\|1yp9]], [[1max\|1max]], [[1tgc\|1tgc]], [[1oph\|1oph]], [[3bte\|3bte]], [[1v2n\|1v2n]], [[3tpi\|3tpi]], [[1eb2\|1eb2]], [[2tio\|2tio]], [[2tld\|2tld]], [[1bty\|1bty]], [[2ptn\|2ptn]], [[2fi5\|2fi5]], [[1v2t\|1v2t]], [[2tga\|2tga]], [[1c2l\|1c2l]], [[1o2v\|1o2v]], [[1o36\|1o36]], [[2cmy\|2cmy]], [[1f0u\|1f0u]], [[1o33\|1o33]], [[1tgt\|1tgt]], [[2by6\|2by6]], [[1c2f\|1c2f]], [[3btq\|3btq]], [[1az8\|1az8]], [[1tgb\|1tgb]], [[1qcp\|1qcp]], [[1o3e\|1o3e]], [[3btt\|3btt]], [[1o3o\|1o3o]], [[1p2i\|1p2i]], [[1tx7\|1tx7]], [[1c2m\|1c2m]], [[1o30\|1o30]], [[1o2z\|1o2z]], [[1sbw\|1sbw]], [[1y5a\|1y5a]], [[1aq7\|1aq7]], [[1s0r\|1s0r]], [[1qbo\|1qbo]], [[1oyq\|1oyq]], [[1btw\|1btw]], [[1xuj\|1xuj]], [[1utq\|1utq]], [[1v2q\|1v2q]], [[1mtu\|1mtu]], [[1tgn\|1tgn]], [[1k1p\|1k1p]], [[1k1j\|1k1j]], [[1gi3\|1gi3]], [[1tpp\|1tpp]], [[1o2q\|1o2q]], [[1o3a\|1o3a]], [[1c9t\|1c9t]], [[1g9i\|1g9i]], [[1hj9\|1hj9]], [[1gi4\|1gi4]], [[1ox1\|1ox1]], [[2ftm\|2ftm]], [[2xtt\|2xtt]], [[1v2w\|1v2w]], [[2blv\|2blv]], [[1ql7\|1ql7]], [[1g3b\|1g3b]], [[1tld\|1tld]], [[1mtw\|1mtw]], [[1qa0\|1qa0]], [[1lqe\|1lqe]], [[1o3f\|1o3f]], [[1tnh\|1tnh]], [[1xug\|1xug]], [[1o3b\|1o3b]], [[1o3j\|1o3j]], [[1rxp\|1rxp]], [[1c1r\|1c1r]], [[1tni\|1tni]], [[1btz\|1btz]], [[1y3v\|1y3v]], [[3btw\|3btw]], [[1v2m\|1v2m]], [[1nc6\|1nc6]], [[1o2u\|1o2u]], [[1yyy\|1yyy]], [[1c2g\|1c2g]], [[3btd\|3btd]], [[1c1s\|1c1s]], [[1taw\|1taw]], [[1zzz\|1zzz]], [[2tgp\|2tgp]], [[1jrs\|1jrs]], [[1tnl\|1tnl]], [[2fx4\|2fx4]], [[1c1o\|1c1o]], [[1f0t\|1f0t]], [[1n6y\|1n6y]], [[1zr0\|1zr0]], [[1k1n\|1k1n]], [[1v2u\|1v2u]], [[1jir\|1jir]], [[1may\|1may]], [[2ah4\|2ah4]], [[2by5\|2by5]], [[1xuk\|1xuk]], [[1gi0\|1gi0]], [[2uuy\|2uuy]], [[1tyn\|1tyn]], [[1tgs\|1tgs]], [[1o31\|1o31]], [[1v2p\|1v2p]], [[2a7h\|2a7h]], [[2tpi\|2tpi]], [[1o37\|1o37]], [[1qbn\|1qbn]], [[2bya\|2bya]], [[1v2l\|1v2l]], [[1o2j\|1o2j]], [[4tpi\|4tpi]], [[1sfi\|1sfi]], [[1p2k\|1p2k]], [[1o34\|1o34]], [[1g36\|1g36]], [[1xuh\|1xuh]], [[2bza\|2bza]], [[1c5v\|1c5v]], [[1gbt\|1gbt]], [[1g3c\|1g3c]], [[3btg\|3btg]], [[1pph\|1pph]], [[1cu9\|1cu9]], [[3ptb\|3ptb]], [[1o3n\|1o3n]], [[1o3g\|1o3g]], [[1c5r\|1c5r]], [[1c5s\|1c5s]], [[1xuf\|1xuf]], [[1tnj\|1tnj]], [[2by9\|2by9]], [[1o2n\|1o2n]], [[1c2k\|1c2k]], [[1gj6\|1gj6]], [[1y3w\|1y3w]], [[1auj\|1auj]], [[1o2p\|1o2p]], [[2j9n\|2j9n]], [[4abi\|4abi]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Trypsin Trypsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.4 3.4.21.4] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Trypsin Trypsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.4 3.4.21.4] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4abj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4abj OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4abj RCSB], [http://www.ebi.ac.uk/pdbsum/4abj PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4abj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4abj OCA], [http://pdbe.org/4abj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4abj RCSB], [http://www.ebi.ac.uk/pdbsum/4abj PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4abj ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 19:		Line 20:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 4abj" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
	*[[Trypsin\|Trypsin]]		*[[Trypsin\|Trypsin]]
		+	*[[Trypsin inhibitor\|Trypsin inhibitor]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 22:18, 24 December 2014

OCA — Wed, 24 Dec 2014 22:18:14 GMT

←Older revision		Revision as of 22:18, 24 December 2014
Line 9:		Line 9:
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4abj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4abj OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4abj RCSB], [http://www.ebi.ac.uk/pdbsum/4abj PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4abj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4abj OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4abj RCSB], [http://www.ebi.ac.uk/pdbsum/4abj PDBsum]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/SFTI1_HELAN SFTI1_HELAN]] Inhibits trypsin, cathepsin G, elastase, chymotrypsin and thrombin. Does not inhibit factor Xa.<ref>PMID:10390350</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==

OCA at 15:15, 9 December 2014

OCA — Tue, 09 Dec 2014 15:15:01 GMT

←Older revision		Revision as of 15:15, 9 December 2014
Line 1:		Line 1:
-	[[~~Image:~~4abj.~~png~~\|~~left~~\|~~200px~~]]	+	==Co-complex structure of bovine trypsin with a modified Bowman-Birk inhibitor (IcA)SFTI-1(1,14), that was 1,5-disubstituted with 1,2,3- trizol to mimic a cis amid bond==
		+	<StructureSection load='4abj' size='340' side='right' caption='[[4abj]], [[Resolution\|resolution]] 1.45Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[4abj]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ABJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ABJ FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=DMF:DIMETHYLFORMAMIDE'>DMF</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
		+	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=PLW:(2S)-2-[5-(1S,2S)-(1-AMINO-2-METHYL-BUTYL)-[1,2,3]TRIAZOL-1-YL]-PROPIONIC+ACID'>PLW</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5ptp\|5ptp]], [[1o2s\|1o2s]], [[1o2t\|1o2t]], [[1bjv\|1bjv]], [[1c2d\|1c2d]], [[1c2e\|1c2e]], [[1mts\|1mts]], [[1tps\|1tps]], [[1tng\|1tng]], [[1o2m\|1o2m]], [[1c1p\|1c1p]], [[1jrt\|1jrt]], [[2btc\|2btc]], [[1c1t\|1c1t]], [[1tnk\|1tnk]], [[1o2x\|1o2x]], [[1d6r\|1d6r]], [[1c2h\|1c2h]], [[1o38\|1o38]], [[1utp\|1utp]], [[1f2s\|1f2s]], [[1gi1\|1gi1]], [[1tio\|1tio]], [[1v2k\|1v2k]], [[1tpo\|1tpo]], [[2blw\|2blw]], [[1v2o\|1v2o]], [[2fx6\|2fx6]], [[1c1n\|1c1n]], [[1y3u\|1y3u]], [[1y3x\|1y3x]], [[1c5p\|1c5p]], [[1o2i\|1o2i]], [[1c2j\|1c2j]], [[1n6x\|1n6x]], [[1c5u\|1c5u]], [[1o3m\|1o3m]], [[1k1o\|1k1o]], [[1v2v\|1v2v]], [[1ghz\|1ghz]], [[1y5u\|1y5u]], [[2fi3\|2fi3]], [[1qb1\|1qb1]], [[2ptc\|2ptc]], [[1k1l\|1k1l]], [[2tgd\|2tgd]], [[1y5b\|1y5b]], [[1c5t\|1c5t]], [[1p2j\|1p2j]], [[1smf\|1smf]], [[1btp\|1btp]], [[1ppe\|1ppe]], [[2ayw\|2ayw]], [[1btx\|1btx]], [[2by8\|2by8]], [[1gi6\|1gi6]], [[1cu8\|1cu8]], [[1c5q\|1c5q]], [[1ntp\|1ntp]], [[1qb9\|1qb9]], [[1g3e\|1g3e]], [[1o35\|1o35]], [[3btk\|3btk]], [[1ejm\|1ejm]], [[3ptn\|3ptn]], [[1uto\|1uto]], [[1o3h\|1o3h]], [[2fi4\|2fi4]], [[1o3i\|1o3i]], [[1y3y\|1y3y]], [[1o2k\|1o2k]], [[1ppc\|1ppc]], [[1o3d\|1o3d]], [[1o2y\|1o2y]], [[1j8a\|1j8a]], [[1c1q\|1c1q]], [[1o2l\|1o2l]], [[1y59\|1y59]], [[2tgt\|2tgt]], [[3btm\|3btm]], [[1v2s\|1v2s]], [[1o2o\|1o2o]], [[1xui\|1xui]], [[1ql8\|1ql8]], [[3btf\|3btf]], [[1s0q\|1s0q]], [[1o2w\|1o2w]], [[1bju\|1bju]], [[1qb6\|1qb6]], [[1o39\|1o39]], [[1gi5\|1gi5]], [[1tab\|1tab]], [[1gi2\|1gi2]], [[1g3d\|1g3d]], [[1cu7\|1cu7]], [[1tpa\|1tpa]], [[1o2h\|1o2h]], [[2ftl\|2ftl]], [[1mtv\|1mtv]], [[1v2r\|1v2r]], [[1o3l\|1o3l]], [[1o2r\|1o2r]], [[1tx8\|1tx8]], [[1v2j\|1v2j]], [[3bth\|3bth]], [[1o3c\|1o3c]], [[1c2i\|1c2i]], [[1o3k\|1o3k]], [[1ezx\|1ezx]], [[1k1m\|1k1m]], [[1utn\|1utn]], [[1ce5\|1ce5]], [[2by7\|2by7]], [[1o32\|1o32]], [[1k1i\|1k1i]], [[1yp9\|1yp9]], [[1max\|1max]], [[1tgc\|1tgc]], [[1oph\|1oph]], [[3bte\|3bte]], [[1v2n\|1v2n]], [[3tpi\|3tpi]], [[1eb2\|1eb2]], [[2tio\|2tio]], [[2tld\|2tld]], [[1bty\|1bty]], [[2ptn\|2ptn]], [[2fi5\|2fi5]], [[1v2t\|1v2t]], [[2tga\|2tga]], [[1c2l\|1c2l]], [[1o2v\|1o2v]], [[1o36\|1o36]], [[2cmy\|2cmy]], [[1f0u\|1f0u]], [[1o33\|1o33]], [[1tgt\|1tgt]], [[2by6\|2by6]], [[1c2f\|1c2f]], [[3btq\|3btq]], [[1az8\|1az8]], [[1tgb\|1tgb]], [[1qcp\|1qcp]], [[1o3e\|1o3e]], [[3btt\|3btt]], [[1o3o\|1o3o]], [[1p2i\|1p2i]], [[1tx7\|1tx7]], [[1c2m\|1c2m]], [[1o30\|1o30]], [[1o2z\|1o2z]], [[1sbw\|1sbw]], [[1y5a\|1y5a]], [[1aq7\|1aq7]], [[1s0r\|1s0r]], [[1qbo\|1qbo]], [[1oyq\|1oyq]], [[1btw\|1btw]], [[1xuj\|1xuj]], [[1utq\|1utq]], [[1v2q\|1v2q]], [[1mtu\|1mtu]], [[1tgn\|1tgn]], [[1k1p\|1k1p]], [[1k1j\|1k1j]], [[1gi3\|1gi3]], [[1tpp\|1tpp]], [[1o2q\|1o2q]], [[1o3a\|1o3a]], [[1c9t\|1c9t]], [[1g9i\|1g9i]], [[1hj9\|1hj9]], [[1gi4\|1gi4]], [[1ox1\|1ox1]], [[2ftm\|2ftm]], [[2xtt\|2xtt]], [[1v2w\|1v2w]], [[2blv\|2blv]], [[1ql7\|1ql7]], [[1g3b\|1g3b]], [[1tld\|1tld]], [[1mtw\|1mtw]], [[1qa0\|1qa0]], [[1lqe\|1lqe]], [[1o3f\|1o3f]], [[1tnh\|1tnh]], [[1xug\|1xug]], [[1o3b\|1o3b]], [[1o3j\|1o3j]], [[1rxp\|1rxp]], [[1c1r\|1c1r]], [[1tni\|1tni]], [[1btz\|1btz]], [[1y3v\|1y3v]], [[3btw\|3btw]], [[1v2m\|1v2m]], [[1nc6\|1nc6]], [[1o2u\|1o2u]], [[1yyy\|1yyy]], [[1c2g\|1c2g]], [[3btd\|3btd]], [[1c1s\|1c1s]], [[1taw\|1taw]], [[1zzz\|1zzz]], [[2tgp\|2tgp]], [[1jrs\|1jrs]], [[1tnl\|1tnl]], [[2fx4\|2fx4]], [[1c1o\|1c1o]], [[1f0t\|1f0t]], [[1n6y\|1n6y]], [[1zr0\|1zr0]], [[1k1n\|1k1n]], [[1v2u\|1v2u]], [[1jir\|1jir]], [[1may\|1may]], [[2ah4\|2ah4]], [[2by5\|2by5]], [[1xuk\|1xuk]], [[1gi0\|1gi0]], [[2uuy\|2uuy]], [[1tyn\|1tyn]], [[1tgs\|1tgs]], [[1o31\|1o31]], [[1v2p\|1v2p]], [[2a7h\|2a7h]], [[2tpi\|2tpi]], [[1o37\|1o37]], [[1qbn\|1qbn]], [[2bya\|2bya]], [[1v2l\|1v2l]], [[1o2j\|1o2j]], [[4tpi\|4tpi]], [[1sfi\|1sfi]], [[1p2k\|1p2k]], [[1o34\|1o34]], [[1g36\|1g36]], [[1xuh\|1xuh]], [[2bza\|2bza]], [[1c5v\|1c5v]], [[1gbt\|1gbt]], [[1g3c\|1g3c]], [[3btg\|3btg]], [[1pph\|1pph]], [[1cu9\|1cu9]], [[3ptb\|3ptb]], [[1o3n\|1o3n]], [[1o3g\|1o3g]], [[1c5r\|1c5r]], [[1c5s\|1c5s]], [[1xuf\|1xuf]], [[1tnj\|1tnj]], [[2by9\|2by9]], [[1o2n\|1o2n]], [[1c2k\|1c2k]], [[1gj6\|1gj6]], [[1y3w\|1y3w]], [[1auj\|1auj]], [[1o2p\|1o2p]], [[2j9n\|2j9n]], [[4abi\|4abi]]</td></tr>
		+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Trypsin Trypsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.4 3.4.21.4] </span></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4abj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4abj OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4abj RCSB], [http://www.ebi.ac.uk/pdbsum/4abj PDBsum]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Flower power: Potent protease inhibitors containing triazolyl mimics of cis and trans backbone amides were engineered based on the structure of the sunflower trypsin inhibitor 1. The biologically relevant cis-Pro motif was successfully replaced with a non-prolyl unit. High-resolution crystal structures of 1,4- and 1,5-disubstituted 1,2,3-triazolyl peptidomimetics can serve in the design of tailor-made Bowman-Birk inhibitors.

-	~~{{STRUCTURE_4abj\| PDB=4abj \| SCENE= }}~~	+	Braces for the Peptide backbone: insights into structure-activity relationships of protease inhibitor mimics with locked amide conformations.,Tischler M, Nasu D, Empting M, Schmelz S, Heinz DW, Rottmann P, Kolmar H, Buntkowsky G, Tietze D, Avrutina O Angew Chem Int Ed Engl. 2012 Apr 10;51(15):3708-12. doi: 10.1002/anie.201108983. , Epub 2012 Feb 28. PMID:22374650<ref>PMID:22374650</ref>

-	~~===Co-complex structure of bovine trypsin with a modified Bowman-Birk inhibitor (IcA)SFTI-1(1~~,~~14), that was 1,5-disubstituted with 1,2,3- trizol to mimic~~ a ~~cis amid bond===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_22374650}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[4abj]] is a 2 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Bos_taurus Bos taurus]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=4ABJ OCA].~~	+

	==See Also==		==See Also==
	*[[Trypsin\|Trypsin]]		*[[Trypsin\|Trypsin]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	<~~ref group="xtra">PMID:022374650<~~/~~ref~~><~~references group="xtra"~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Bos taurus]]		[[Category: Bos taurus]]
	[[Category: Trypsin]]		[[Category: Trypsin]]
-	[[Category: Empting, M.]]	+	[[Category: Empting, M]]
-	[[Category: Heinz, D.]]	+	[[Category: Heinz, D]]
-	[[Category: Kolmar, H.]]	+	[[Category: Kolmar, H]]
-	[[Category: Nasu, D.]]	+	[[Category: Nasu, D]]
-	[[Category: Schmelz, S.]]	+	[[Category: Schmelz, S]]
-	[[Category: Tischler, M.]]	+	[[Category: Tischler, M]]
	[[Category: Amide mimic]]		[[Category: Amide mimic]]
	[[Category: Hydrolase-inhibitor complex]]		[[Category: Hydrolase-inhibitor complex]]

OCA at 09:42, 20 October 2012

OCA — Sat, 20 Oct 2012 09:42:01 GMT

←Older revision		Revision as of 09:42, 20 October 2012
Line 8:		Line 8:

	==About this Structure==		==About this Structure==
-	[[4abj]] is a 2 chain structure ~~of [[Trypsin]]~~ with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ABJ OCA].	+	[[4abj]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ABJ OCA].

	==See Also==		==See Also==

OCA at 23:41, 25 July 2012

OCA — Wed, 25 Jul 2012 23:41:31 GMT

←Older revision		Revision as of 23:41, 25 July 2012
Line 1:		Line 1:
	[[Image:4abj.png\|left\|200px]]		[[Image:4abj.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_4abj", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_4abj\| PDB=4abj \| SCENE= }}		{{STRUCTURE_4abj\| PDB=4abj \| SCENE= }}

	===Co-complex structure of bovine trypsin with a modified Bowman-Birk inhibitor (IcA)SFTI-1(1,14), that was 1,5-disubstituted with 1,2,3- trizol to mimic a cis amid bond===		===Co-complex structure of bovine trypsin with a modified Bowman-Birk inhibitor (IcA)SFTI-1(1,14), that was 1,5-disubstituted with 1,2,3- trizol to mimic a cis amid bond===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_22374650}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 22374650 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_22374650}}		{{ABSTRACT_PUBMED_22374650}}

	==About this Structure==		==About this Structure==
-	[[4abj]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ABJ OCA].	+	[[4abj]] is a 2 chain structure of [[Trypsin]] with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ABJ OCA].
		+
		+	==See Also==
		+	*[[Trypsin\|Trypsin]]

	==Reference==		==Reference==

OCA at 07:02, 18 April 2012

OCA — Wed, 18 Apr 2012 07:02:05 GMT

←Older revision		Revision as of 07:02, 18 April 2012
Line 1:		Line 1:
-	[[Image:4abj.~~jpg~~\|left\|200px]]	+	[[Image:4abj.png\|left\|200px]]

	<!--		<!--
Line 11:		Line 11:
	===Co-complex structure of bovine trypsin with a modified Bowman-Birk inhibitor (IcA)SFTI-1(1,14), that was 1,5-disubstituted with 1,2,3- trizol to mimic a cis amid bond===		===Co-complex structure of bovine trypsin with a modified Bowman-Birk inhibitor (IcA)SFTI-1(1,14), that was 1,5-disubstituted with 1,2,3- trizol to mimic a cis amid bond===

		+
		+	<!--
		+	The line below this paragraph, {{ABSTRACT_PUBMED_22374650}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 22374650 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_22374650}}

	==About this Structure==		==About this Structure==
	[[4abj]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ABJ OCA].		[[4abj]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ABJ OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:022374650</ref><references group="xtra"/>
	[[Category: Bos taurus]]		[[Category: Bos taurus]]
	[[Category: Trypsin]]		[[Category: Trypsin]]

←Older revision		Revision as of 05:28, 25 August 2022
Line 3:		Line 3:
	<StructureSection load='4abj' size='340' side='right'caption='[[4abj]], [[Resolution\|resolution]] 1.45Å' scene=''>		<StructureSection load='4abj' size='340' side='right'caption='[[4abj]], [[Resolution\|resolution]] 1.45Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4abj]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ABJ OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=4ABJ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4abj]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ABJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4ABJ FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=DMF:DIMETHYLFORMAMIDE'>DMF</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=DMF:DIMETHYLFORMAMIDE'>DMF</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=PLW:(2S)-2-[5-(1S,2S)-(1-AMINO-2-METHYL-BUTYL)-[1,2,3]TRIAZOL-1-YL]-PROPIONIC+ACID'>PLW</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=PLW:(2S)-2-[5-(1S,2S)-(1-AMINO-2-METHYL-BUTYL)-[1,2,3]TRIAZOL-1-YL]-PROPIONIC+ACID'>PLW</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[5ptp\|5ptp]], [[1o2s\|1o2s]], [[1o2t\|1o2t]], [[1bjv\|1bjv]], [[1c2d\|1c2d]], [[1c2e\|1c2e]], [[1mts\|1mts]], [[1tps\|1tps]], [[1tng\|1tng]], [[1o2m\|1o2m]], [[1c1p\|1c1p]], [[1jrt\|1jrt]], [[2btc\|2btc]], [[1c1t\|1c1t]], [[1tnk\|1tnk]], [[1o2x\|1o2x]], [[1d6r\|1d6r]], [[1c2h\|1c2h]], [[1o38\|1o38]], [[1utp\|1utp]], [[1f2s\|1f2s]], [[1gi1\|1gi1]], [[1tio\|1tio]], [[1v2k\|1v2k]], [[1tpo\|1tpo]], [[2blw\|2blw]], [[1v2o\|1v2o]], [[2fx6\|2fx6]], [[1c1n\|1c1n]], [[1y3u\|1y3u]], [[1y3x\|1y3x]], [[1c5p\|1c5p]], [[1o2i\|1o2i]], [[1c2j\|1c2j]], [[1n6x\|1n6x]], [[1c5u\|1c5u]], [[1o3m\|1o3m]], [[1k1o\|1k1o]], [[1v2v\|1v2v]], [[1ghz\|1ghz]], [[1y5u\|1y5u]], [[2fi3\|2fi3]], [[1qb1\|1qb1]], [[2ptc\|2ptc]], [[1k1l\|1k1l]], [[2tgd\|2tgd]], [[1y5b\|1y5b]], [[1c5t\|1c5t]], [[1p2j\|1p2j]], [[1smf\|1smf]], [[1btp\|1btp]], [[1ppe\|1ppe]], [[2ayw\|2ayw]], [[1btx\|1btx]], [[2by8\|2by8]], [[1gi6\|1gi6]], [[1cu8\|1cu8]], [[1c5q\|1c5q]], [[1ntp\|1ntp]], [[1qb9\|1qb9]], [[1g3e\|1g3e]], [[1o35\|1o35]], [[3btk\|3btk]], [[1ejm\|1ejm]], [[3ptn\|3ptn]], [[1uto\|1uto]], [[1o3h\|1o3h]], [[2fi4\|2fi4]], [[1o3i\|1o3i]], [[1y3y\|1y3y]], [[1o2k\|1o2k]], [[1ppc\|1ppc]], [[1o3d\|1o3d]], [[1o2y\|1o2y]], [[1j8a\|1j8a]], [[1c1q\|1c1q]], [[1o2l\|1o2l]], [[1y59\|1y59]], [[2tgt\|2tgt]], [[3btm\|3btm]], [[1v2s\|1v2s]], [[1o2o\|1o2o]], [[1xui\|1xui]], [[1ql8\|1ql8]], [[3btf\|3btf]], [[1s0q\|1s0q]], [[1o2w\|1o2w]], [[1bju\|1bju]], [[1qb6\|1qb6]], [[1o39\|1o39]], [[1gi5\|1gi5]], [[1tab\|1tab]], [[1gi2\|1gi2]], [[1g3d\|1g3d]], [[1cu7\|1cu7]], [[1tpa\|1tpa]], [[1o2h\|1o2h]], [[2ftl\|2ftl]], [[1mtv\|1mtv]], [[1v2r\|1v2r]], [[1o3l\|1o3l]], [[1o2r\|1o2r]], [[1tx8\|1tx8]], [[1v2j\|1v2j]], [[3bth\|3bth]], [[1o3c\|1o3c]], [[1c2i\|1c2i]], [[1o3k\|1o3k]], [[1ezx\|1ezx]], [[1k1m\|1k1m]], [[1utn\|1utn]], [[1ce5\|1ce5]], [[2by7\|2by7]], [[1o32\|1o32]], [[1k1i\|1k1i]], [[1yp9\|1yp9]], [[1max\|1max]], [[1tgc\|1tgc]], [[1oph\|1oph]], [[3bte\|3bte]], [[1v2n\|1v2n]], [[3tpi\|3tpi]], [[1eb2\|1eb2]], [[2tio\|2tio]], [[2tld\|2tld]], [[1bty\|1bty]], [[2ptn\|2ptn]], [[2fi5\|2fi5]], [[1v2t\|1v2t]], [[2tga\|2tga]], [[1c2l\|1c2l]], [[1o2v\|1o2v]], [[1o36\|1o36]], [[2cmy\|2cmy]], [[1f0u\|1f0u]], [[1o33\|1o33]], [[1tgt\|1tgt]], [[2by6\|2by6]], [[1c2f\|1c2f]], [[3btq\|3btq]], [[1az8\|1az8]], [[1tgb\|1tgb]], [[1qcp\|1qcp]], [[1o3e\|1o3e]], [[3btt\|3btt]], [[1o3o\|1o3o]], [[1p2i\|1p2i]], [[1tx7\|1tx7]], [[1c2m\|1c2m]], [[1o30\|1o30]], [[1o2z\|1o2z]], [[1sbw\|1sbw]], [[1y5a\|1y5a]], [[1aq7\|1aq7]], [[1s0r\|1s0r]], [[1qbo\|1qbo]], [[1oyq\|1oyq]], [[1btw\|1btw]], [[1xuj\|1xuj]], [[1utq\|1utq]], [[1v2q\|1v2q]], [[1mtu\|1mtu]], [[1tgn\|1tgn]], [[1k1p\|1k1p]], [[1k1j\|1k1j]], [[1gi3\|1gi3]], [[1tpp\|1tpp]], [[1o2q\|1o2q]], [[1o3a\|1o3a]], [[1c9t\|1c9t]], [[1g9i\|1g9i]], [[1hj9\|1hj9]], [[1gi4\|1gi4]], [[1ox1\|1ox1]], [[2ftm\|2ftm]], [[2xtt\|2xtt]], [[1v2w\|1v2w]], [[2blv\|2blv]], [[1ql7\|1ql7]], [[1g3b\|1g3b]], [[1tld\|1tld]], [[1mtw\|1mtw]], [[1qa0\|1qa0]], [[1lqe\|1lqe]], [[1o3f\|1o3f]], [[1tnh\|1tnh]], [[1xug\|1xug]], [[1o3b\|1o3b]], [[1o3j\|1o3j]], [[1rxp\|1rxp]], [[1c1r\|1c1r]], [[1tni\|1tni]], [[1btz\|1btz]], [[1y3v\|1y3v]], [[3btw\|3btw]], [[1v2m\|1v2m]], [[1nc6\|1nc6]], [[1o2u\|1o2u]], [[1yyy\|1yyy]], [[1c2g\|1c2g]], [[3btd\|3btd]], [[1c1s\|1c1s]], [[1taw\|1taw]], [[1zzz\|1zzz]], [[2tgp\|2tgp]], [[1jrs\|1jrs]], [[1tnl\|1tnl]], [[2fx4\|2fx4]], [[1c1o\|1c1o]], [[1f0t\|1f0t]], [[1n6y\|1n6y]], [[1zr0\|1zr0]], [[1k1n\|1k1n]], [[1v2u\|1v2u]], [[1jir\|1jir]], [[1may\|1may]], [[2ah4\|2ah4]], [[2by5\|2by5]], [[1xuk\|1xuk]], [[1gi0\|1gi0]], [[2uuy\|2uuy]], [[1tyn\|1tyn]], [[1tgs\|1tgs]], [[1o31\|1o31]], [[1v2p\|1v2p]], [[2a7h\|2a7h]], [[2tpi\|2tpi]], [[1o37\|1o37]], [[1qbn\|1qbn]], [[2bya\|2bya]], [[1v2l\|1v2l]], [[1o2j\|1o2j]], [[4tpi\|4tpi]], [[1sfi\|1sfi]], [[1p2k\|1p2k]], [[1o34\|1o34]], [[1g36\|1g36]], [[1xuh\|1xuh]], [[2bza\|2bza]], [[1c5v\|1c5v]], [[1gbt\|1gbt]], [[1g3c\|1g3c]], [[3btg\|3btg]], [[1pph\|1pph]], [[1cu9\|1cu9]], [[3ptb\|3ptb]], [[1o3n\|1o3n]], [[1o3g\|1o3g]], [[1c5r\|1c5r]], [[1c5s\|1c5s]], [[1xuf\|1xuf]], [[1tnj\|1tnj]], [[2by9\|2by9]], [[1o2n\|1o2n]], [[1c2k\|1c2k]], [[1gj6\|1gj6]], [[1y3w\|1y3w]], [[1auj\|1auj]], [[1o2p\|1o2p]], [[2j9n\|2j9n]], [[4abi\|4abi]]</div></td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[5ptp\|5ptp]], [[1o2s\|1o2s]], [[1o2t\|1o2t]], [[1bjv\|1bjv]], [[1c2d\|1c2d]], [[1c2e\|1c2e]], [[1mts\|1mts]], [[1tps\|1tps]], [[1tng\|1tng]], [[1o2m\|1o2m]], [[1c1p\|1c1p]], [[1jrt\|1jrt]], [[2btc\|2btc]], [[1c1t\|1c1t]], [[1tnk\|1tnk]], [[1o2x\|1o2x]], [[1d6r\|1d6r]], [[1c2h\|1c2h]], [[1o38\|1o38]], [[1utp\|1utp]], [[1f2s\|1f2s]], [[1gi1\|1gi1]], [[1tio\|1tio]], [[1v2k\|1v2k]], [[1tpo\|1tpo]], [[2blw\|2blw]], [[1v2o\|1v2o]], [[2fx6\|2fx6]], [[1c1n\|1c1n]], [[1y3u\|1y3u]], [[1y3x\|1y3x]], [[1c5p\|1c5p]], [[1o2i\|1o2i]], [[1c2j\|1c2j]], [[1n6x\|1n6x]], [[1c5u\|1c5u]], [[1o3m\|1o3m]], [[1k1o\|1k1o]], [[1v2v\|1v2v]], [[1ghz\|1ghz]], [[1y5u\|1y5u]], [[2fi3\|2fi3]], [[1qb1\|1qb1]], [[2ptc\|2ptc]], [[1k1l\|1k1l]], [[2tgd\|2tgd]], [[1y5b\|1y5b]], [[1c5t\|1c5t]], [[1p2j\|1p2j]], [[1smf\|1smf]], [[1btp\|1btp]], [[1ppe\|1ppe]], [[2ayw\|2ayw]], [[1btx\|1btx]], [[2by8\|2by8]], [[1gi6\|1gi6]], [[1cu8\|1cu8]], [[1c5q\|1c5q]], [[1ntp\|1ntp]], [[1qb9\|1qb9]], [[1g3e\|1g3e]], [[1o35\|1o35]], [[3btk\|3btk]], [[1ejm\|1ejm]], [[3ptn\|3ptn]], [[1uto\|1uto]], [[1o3h\|1o3h]], [[2fi4\|2fi4]], [[1o3i\|1o3i]], [[1y3y\|1y3y]], [[1o2k\|1o2k]], [[1ppc\|1ppc]], [[1o3d\|1o3d]], [[1o2y\|1o2y]], [[1j8a\|1j8a]], [[1c1q\|1c1q]], [[1o2l\|1o2l]], [[1y59\|1y59]], [[2tgt\|2tgt]], [[3btm\|3btm]], [[1v2s\|1v2s]], [[1o2o\|1o2o]], [[1xui\|1xui]], [[1ql8\|1ql8]], [[3btf\|3btf]], [[1s0q\|1s0q]], [[1o2w\|1o2w]], [[1bju\|1bju]], [[1qb6\|1qb6]], [[1o39\|1o39]], [[1gi5\|1gi5]], [[1tab\|1tab]], [[1gi2\|1gi2]], [[1g3d\|1g3d]], [[1cu7\|1cu7]], [[1tpa\|1tpa]], [[1o2h\|1o2h]], [[2ftl\|2ftl]], [[1mtv\|1mtv]], [[1v2r\|1v2r]], [[1o3l\|1o3l]], [[1o2r\|1o2r]], [[1tx8\|1tx8]], [[1v2j\|1v2j]], [[3bth\|3bth]], [[1o3c\|1o3c]], [[1c2i\|1c2i]], [[1o3k\|1o3k]], [[1ezx\|1ezx]], [[1k1m\|1k1m]], [[1utn\|1utn]], [[1ce5\|1ce5]], [[2by7\|2by7]], [[1o32\|1o32]], [[1k1i\|1k1i]], [[1yp9\|1yp9]], [[1max\|1max]], [[1tgc\|1tgc]], [[1oph\|1oph]], [[3bte\|3bte]], [[1v2n\|1v2n]], [[3tpi\|3tpi]], [[1eb2\|1eb2]], [[2tio\|2tio]], [[2tld\|2tld]], [[1bty\|1bty]], [[2ptn\|2ptn]], [[2fi5\|2fi5]], [[1v2t\|1v2t]], [[2tga\|2tga]], [[1c2l\|1c2l]], [[1o2v\|1o2v]], [[1o36\|1o36]], [[2cmy\|2cmy]], [[1f0u\|1f0u]], [[1o33\|1o33]], [[1tgt\|1tgt]], [[2by6\|2by6]], [[1c2f\|1c2f]], [[3btq\|3btq]], [[1az8\|1az8]], [[1tgb\|1tgb]], [[1qcp\|1qcp]], [[1o3e\|1o3e]], [[3btt\|3btt]], [[1o3o\|1o3o]], [[1p2i\|1p2i]], [[1tx7\|1tx7]], [[1c2m\|1c2m]], [[1o30\|1o30]], [[1o2z\|1o2z]], [[1sbw\|1sbw]], [[1y5a\|1y5a]], [[1aq7\|1aq7]], [[1s0r\|1s0r]], [[1qbo\|1qbo]], [[1oyq\|1oyq]], [[1btw\|1btw]], [[1xuj\|1xuj]], [[1utq\|1utq]], [[1v2q\|1v2q]], [[1mtu\|1mtu]], [[1tgn\|1tgn]], [[1k1p\|1k1p]], [[1k1j\|1k1j]], [[1gi3\|1gi3]], [[1tpp\|1tpp]], [[1o2q\|1o2q]], [[1o3a\|1o3a]], [[1c9t\|1c9t]], [[1g9i\|1g9i]], [[1hj9\|1hj9]], [[1gi4\|1gi4]], [[1ox1\|1ox1]], [[2ftm\|2ftm]], [[2xtt\|2xtt]], [[1v2w\|1v2w]], [[2blv\|2blv]], [[1ql7\|1ql7]], [[1g3b\|1g3b]], [[1tld\|1tld]], [[1mtw\|1mtw]], [[1qa0\|1qa0]], [[1lqe\|1lqe]], [[1o3f\|1o3f]], [[1tnh\|1tnh]], [[1xug\|1xug]], [[1o3b\|1o3b]], [[1o3j\|1o3j]], [[1rxp\|1rxp]], [[1c1r\|1c1r]], [[1tni\|1tni]], [[1btz\|1btz]], [[1y3v\|1y3v]], [[3btw\|3btw]], [[1v2m\|1v2m]], [[1nc6\|1nc6]], [[1o2u\|1o2u]], [[1yyy\|1yyy]], [[1c2g\|1c2g]], [[3btd\|3btd]], [[1c1s\|1c1s]], [[1taw\|1taw]], [[1zzz\|1zzz]], [[2tgp\|2tgp]], [[1jrs\|1jrs]], [[1tnl\|1tnl]], [[2fx4\|2fx4]], [[1c1o\|1c1o]], [[1f0t\|1f0t]], [[1n6y\|1n6y]], [[1zr0\|1zr0]], [[1k1n\|1k1n]], [[1v2u\|1v2u]], [[1jir\|1jir]], [[1may\|1may]], [[2ah4\|2ah4]], [[2by5\|2by5]], [[1xuk\|1xuk]], [[1gi0\|1gi0]], [[2uuy\|2uuy]], [[1tyn\|1tyn]], [[1tgs\|1tgs]], [[1o31\|1o31]], [[1v2p\|1v2p]], [[2a7h\|2a7h]], [[2tpi\|2tpi]], [[1o37\|1o37]], [[1qbn\|1qbn]], [[2bya\|2bya]], [[1v2l\|1v2l]], [[1o2j\|1o2j]], [[4tpi\|4tpi]], [[1sfi\|1sfi]], [[1p2k\|1p2k]], [[1o34\|1o34]], [[1g36\|1g36]], [[1xuh\|1xuh]], [[2bza\|2bza]], [[1c5v\|1c5v]], [[1gbt\|1gbt]], [[1g3c\|1g3c]], [[3btg\|3btg]], [[1pph\|1pph]], [[1cu9\|1cu9]], [[3ptb\|3ptb]], [[1o3n\|1o3n]], [[1o3g\|1o3g]], [[1c5r\|1c5r]], [[1c5s\|1c5s]], [[1xuf\|1xuf]], [[1tnj\|1tnj]], [[2by9\|2by9]], [[1o2n\|1o2n]], [[1c2k\|1c2k]], [[1gj6\|1gj6]], [[1y3w\|1y3w]], [[1auj\|1auj]], [[1o2p\|1o2p]], [[2j9n\|2j9n]], [[4abi\|4abi]]</div></td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/Trypsin Trypsin], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.4 3.4.21.4] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Trypsin Trypsin], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.4 3.4.21.4] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=4abj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4abj OCA], [~~http~~://pdbe.org/4abj PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4abj RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4abj PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4abj ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4abj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4abj OCA], [https://pdbe.org/4abj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4abj RCSB], [https://www.ebi.ac.uk/pdbsum/4abj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4abj ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/SFTI1_HELAN SFTI1_HELAN]] Inhibits trypsin, cathepsin G, elastase, chymotrypsin and thrombin. Does not inhibit factor Xa.<ref>PMID:10390350</ref>	+	[[https://www.uniprot.org/uniprot/SFTI1_HELAN SFTI1_HELAN]] Inhibits trypsin, cathepsin G, elastase, chymotrypsin and thrombin. Does not inhibit factor Xa.<ref>PMID:10390350</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==