4ai5 - Revision history

OCA at 11:27, 20 December 2023

OCA — Wed, 20 Dec 2023 11:27:37 GMT

←Older revision		Revision as of 11:27, 20 December 2023
Line 3:		Line 3:
	<StructureSection load='4ai5' size='340' side='right'caption='[[4ai5]], [[Resolution\|resolution]] 2.22Å' scene=''>		<StructureSection load='4ai5' size='340' side='right'caption='[[4ai5]], [[Resolution\|resolution]] 2.22Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4ai5]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Staas Staas~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AI5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4AI5 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4ai5]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_MSSA476 Staphylococcus aureus subsp. aureus MSSA476]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AI5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4AI5 FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=ADK:3~~-~~METHYL-3H-PURIN-6-YLAMINE'>ADK</scene>~~, ~~<scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.22Å</td></tr>
-	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"><~~div style~~='~~overflow~~: ~~auto; max~~-~~height: 3em;~~'>~~[[2jg6\|2jg6]], [[4ai4\|4ai4]]~~</~~div~~><~~/td></tr>~~	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADK:3-METHYL-3H-PURIN-6-YLAMINE'>ADK</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-	~~<tr id~~='~~activity'><td class~~=~~"sblockLbl"><b>Activity~~:~~</b~~></td><~~td class~~=~~"sblockDat"><span class~~=~~'plainlinks~~'>~~[https://en.wikipedia.org/wiki/DNA-3-methyladenine_glycosylase_I DNA-3-methyladenine glycosylase I], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.2.20 3.2.2.20]~~ </~~span~~></td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ai5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ai5 OCA], [https://pdbe.org/4ai5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ai5 RCSB], [https://www.ebi.ac.uk/pdbsum/4ai5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ai5 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ai5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ai5 OCA], [https://pdbe.org/4ai5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ai5 RCSB], [https://www.ebi.ac.uk/pdbsum/4ai5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ai5 ProSAT]</span></td></tr>
	</table>		</table>
Line 25:		Line 24:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: DNA-3-methyladenine glycosylase I]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Staas~~]]	+	[[Category: Staphylococcus aureus subsp. aureus MSSA476]]
-	[[Category: Naismith~~, J H~~]]	+	[[Category: Naismith JH]]
-	[[Category: Zhu, X]]	+	[[Category: Zhu X]]
-	~~[[Category: 3-methyladenine recognition]]~~	+
-	~~[[Category: 3-methyladenine tautomer]]~~	+
-	~~[[Category: Dna repair]]~~	+
-	~~[[Category: Hydrolase~~]]	+

OCA at 05:34, 25 August 2022

OCA — Thu, 25 Aug 2022 05:34:53 GMT

←Older revision		Revision as of 05:34, 25 August 2022
Line 3:		Line 3:
	<StructureSection load='4ai5' size='340' side='right'caption='[[4ai5]], [[Resolution\|resolution]] 2.22Å' scene=''>		<StructureSection load='4ai5' size='340' side='right'caption='[[4ai5]], [[Resolution\|resolution]] 2.22Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4ai5]] is a 5 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Staas Staas]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AI5 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4AI5 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4ai5]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Staas Staas]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AI5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4AI5 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADK:3-METHYL-3H-PURIN-6-YLAMINE'>ADK</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADK:3-METHYL-3H-PURIN-6-YLAMINE'>ADK</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2jg6\|2jg6]], [[4ai4\|4ai4]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2jg6\|2jg6]], [[4ai4\|4ai4]]</div></td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/DNA-3-methyladenine_glycosylase_I DNA-3-methyladenine glycosylase I], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.2.20 3.2.2.20] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/DNA-3-methyladenine_glycosylase_I DNA-3-methyladenine glycosylase I], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.2.20 3.2.2.20] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4ai5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ai5 OCA], [~~http~~://pdbe.org/4ai5 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4ai5 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4ai5 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4ai5 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ai5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ai5 OCA], [https://pdbe.org/4ai5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ai5 RCSB], [https://www.ebi.ac.uk/pdbsum/4ai5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ai5 ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 16:54, 29 January 2020

OCA — Wed, 29 Jan 2020 16:54:02 GMT

←Older revision		Revision as of 16:54, 29 January 2020
Line 1:		Line 1:

	==Crystal structure of Y16F of 3-methyladenine DNA glycosylase I (TAG) in complex with 3-methyladenine==		==Crystal structure of Y16F of 3-methyladenine DNA glycosylase I (TAG) in complex with 3-methyladenine==
-	<StructureSection load='4ai5' size='340' side='right' caption='[[4ai5]], [[Resolution\|resolution]] 2.22Å' scene=''>	+	<StructureSection load='4ai5' size='340' side='right'caption='[[4ai5]], [[Resolution\|resolution]] 2.22Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4ai5]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Staas Staas]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AI5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4AI5 FirstGlance]. <br>		<table><tr><td colspan='2'>[[4ai5]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Staas Staas]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AI5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4AI5 FirstGlance]. <br>
Line 20:		Line 20:

	==See Also==		==See Also==
-	*[[DNA glycosylase\|DNA glycosylase]]	+	*[[DNA glycosylase 3D structures\|DNA glycosylase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 26:		Line 26:
	</StructureSection>		</StructureSection>
	[[Category: DNA-3-methyladenine glycosylase I]]		[[Category: DNA-3-methyladenine glycosylase I]]
		+	[[Category: Large Structures]]
	[[Category: Staas]]		[[Category: Staas]]
	[[Category: Naismith, J H]]		[[Category: Naismith, J H]]

OCA at 19:53, 11 August 2016

OCA — Thu, 11 Aug 2016 19:53:09 GMT

←Older revision		Revision as of 19:53, 11 August 2016
Line 1:		Line 1:
		+
	==Crystal structure of Y16F of 3-methyladenine DNA glycosylase I (TAG) in complex with 3-methyladenine==		==Crystal structure of Y16F of 3-methyladenine DNA glycosylase I (TAG) in complex with 3-methyladenine==
	<StructureSection load='4ai5' size='340' side='right' caption='[[4ai5]], [[Resolution\|resolution]] 2.22Å' scene=''>		<StructureSection load='4ai5' size='340' side='right' caption='[[4ai5]], [[Resolution\|resolution]] 2.22Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4ai5]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Staphylococcus_aureus_subsp._aureus_mssa476 Staphylococcus aureus subsp. aureus mssa476~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AI5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4AI5 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4ai5]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Staas Staas]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AI5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4AI5 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADK:3-METHYL-3H-PURIN-6-YLAMINE'>ADK</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADK:3-METHYL-3H-PURIN-6-YLAMINE'>ADK</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2jg6\|2jg6]], [[4ai4\|4ai4]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2jg6\|2jg6]], [[4ai4\|4ai4]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA-3-methyladenine_glycosylase_I DNA-3-methyladenine glycosylase I], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.2.20 3.2.2.20] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA-3-methyladenine_glycosylase_I DNA-3-methyladenine glycosylase I], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.2.20 3.2.2.20] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ai5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ai5 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4ai5 RCSB], [http://www.ebi.ac.uk/pdbsum/4ai5 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ai5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ai5 OCA], [http://pdbe.org/4ai5 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4ai5 RCSB], [http://www.ebi.ac.uk/pdbsum/4ai5 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4ai5 ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 16:		Line 17:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 4ai5" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[DNA glycosylase\|DNA glycosylase]]
	== References ==		== References ==
	<references/>		<references/>
Line 21:		Line 26:
	</StructureSection>		</StructureSection>
	[[Category: DNA-3-methyladenine glycosylase I]]		[[Category: DNA-3-methyladenine glycosylase I]]
-	[[Category: ~~Staphylococcus aureus subsp. aureus mssa476~~]]	+	[[Category: Staas]]
	[[Category: Naismith, J H]]		[[Category: Naismith, J H]]
	[[Category: Zhu, X]]		[[Category: Zhu, X]]

OCA at 09:32, 4 January 2015

OCA — Sun, 04 Jan 2015 09:32:39 GMT

←Older revision		Revision as of 09:32, 4 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4ai5]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_mssa476 Staphylococcus aureus subsp. aureus mssa476]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AI5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4AI5 FirstGlance]. <br>		<table><tr><td colspan='2'>[[4ai5]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_mssa476 Staphylococcus aureus subsp. aureus mssa476]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AI5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4AI5 FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADK:3-METHYL-3H-PURIN-6-YLAMINE'>ADK</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADK:3-METHYL-3H-PURIN-6-YLAMINE'>ADK</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2jg6\|2jg6]], [[4ai4\|4ai4]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2jg6\|2jg6]], [[4ai4\|4ai4]]</td></tr>
-	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA-3-methyladenine_glycosylase_I DNA-3-methyladenine glycosylase I], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.2.20 3.2.2.20] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA-3-methyladenine_glycosylase_I DNA-3-methyladenine glycosylase I], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.2.20 3.2.2.20] </span></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ai5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ai5 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4ai5 RCSB], [http://www.ebi.ac.uk/pdbsum/4ai5 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ai5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ai5 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4ai5 RCSB], [http://www.ebi.ac.uk/pdbsum/4ai5 PDBsum]</span></td></tr>
-	<table>	+	</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 22:		Line 22:
	[[Category: DNA-3-methyladenine glycosylase I]]		[[Category: DNA-3-methyladenine glycosylase I]]
	[[Category: Staphylococcus aureus subsp. aureus mssa476]]		[[Category: Staphylococcus aureus subsp. aureus mssa476]]
-	[[Category: Naismith, J H.]]	+	[[Category: Naismith, J H]]
-	[[Category: Zhu, X.]]	+	[[Category: Zhu, X]]
	[[Category: 3-methyladenine recognition]]		[[Category: 3-methyladenine recognition]]
	[[Category: 3-methyladenine tautomer]]		[[Category: 3-methyladenine tautomer]]
	[[Category: Dna repair]]		[[Category: Dna repair]]
	[[Category: Hydrolase]]		[[Category: Hydrolase]]

OCA at 07:39, 5 June 2014

OCA — Thu, 05 Jun 2014 07:39:03 GMT

←Older revision		Revision as of 07:39, 5 June 2014
Line 1:		Line 1:
-	[[~~Image:~~4ai5.~~png~~\|~~left~~\|~~200px~~]]	+	==Crystal structure of Y16F of 3-methyladenine DNA glycosylase I (TAG) in complex with 3-methyladenine==
		+	<StructureSection load='4ai5' size='340' side='right' caption='[[4ai5]], [[Resolution\|resolution]] 2.22Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[4ai5]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_mssa476 Staphylococcus aureus subsp. aureus mssa476]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AI5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4AI5 FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADK:3-METHYL-3H-PURIN-6-YLAMINE'>ADK</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2jg6\|2jg6]], [[4ai4\|4ai4]]</td></tr>
		+	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA-3-methyladenine_glycosylase_I DNA-3-methyladenine glycosylase I], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.2.20 3.2.2.20] </span></td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ai5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ai5 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4ai5 RCSB], [http://www.ebi.ac.uk/pdbsum/4ai5 PDBsum]</span></td></tr>
		+	<table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The removal of chemically damaged DNA bases such as 3-methyladenine (3-MeA) is an essential process in all living organisms and is catalyzed by the enzyme 3-MeA DNA glycosylase I. A key question is how the enzyme selectively recognizes the alkylated 3-MeA over the much more abundant adenine. The crystal structures of native and Y16F-mutant 3-MeA DNA glycosylase I from Staphylococcus aureus in complex with 3-MeA are reported to 1.8 and 2.2 A resolution, respectively. Isothermal titration calorimetry shows that protonation of 3-MeA decreases its binding affinity, confirming previous fluorescence studies that show that charge-charge recognition is not critical for the selection of 3-MeA over adenine. It is hypothesized that the hydrogen-bonding pattern of Glu38 and Tyr16 of 3-MeA DNA glycosylase I with a particular tautomer unique to 3-MeA contributes to recognition and selection.

-	~~{{STRUCTURE_4ai5\| PDB=4ai5 \| SCENE= }}~~	+	A model for 3-methyladenine recognition by 3-methyladenine DNA glycosylase I (TAG) from Staphylococcus aureus.,Zhu X, Yan X, Carter LG, Liu H, Graham S, Coote PJ, Naismith J Acta Crystallogr Sect F Struct Biol Cryst Commun. 2012 Jun 1;68(Pt 6):610-5. Epub, 2012 May 22. PMID:22684054<ref>PMID:22684054</ref>

-	~~===Crystal structure~~ of ~~Y16F of 3-methyladenine DNA glycosylase I (TAG) in complex with 3-methyladenine===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_22684054}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[4ai5]] is a 5 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Staphylococcus_aureus_subsp~~.~~_aureus_mssa476 Staphylococcus aureus subsp. aureus mssa476]. Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=4AI5 OCA].~~	+	</StructureSection>
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:022684054<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: DNA-3-methyladenine glycosylase I]]		[[Category: DNA-3-methyladenine glycosylase I]]
	[[Category: Staphylococcus aureus subsp. aureus mssa476]]		[[Category: Staphylococcus aureus subsp. aureus mssa476]]

OCA at 07:47, 20 June 2012

OCA — Wed, 20 Jun 2012 07:47:26 GMT

←Older revision		Revision as of 07:47, 20 June 2012
Line 1:		Line 1:
	[[Image:4ai5.png\|left\|200px]]		[[Image:4ai5.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_4ai5", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_4ai5\| PDB=4ai5 \| SCENE= }}		{{STRUCTURE_4ai5\| PDB=4ai5 \| SCENE= }}

	===Crystal structure of Y16F of 3-methyladenine DNA glycosylase I (TAG) in complex with 3-methyladenine===		===Crystal structure of Y16F of 3-methyladenine DNA glycosylase I (TAG) in complex with 3-methyladenine===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_22684054}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 22684054 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_22684054}}		{{ABSTRACT_PUBMED_22684054}}

OCA at 06:55, 20 June 2012

OCA — Wed, 20 Jun 2012 06:55:21 GMT

←Older revision		Revision as of 06:55, 20 June 2012
Line 11:		Line 11:
	===Crystal structure of Y16F of 3-methyladenine DNA glycosylase I (TAG) in complex with 3-methyladenine===		===Crystal structure of Y16F of 3-methyladenine DNA glycosylase I (TAG) in complex with 3-methyladenine===

		+
		+	<!--
		+	The line below this paragraph, {{ABSTRACT_PUBMED_22684054}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 22684054 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_22684054}}

	==About this Structure==		==About this Structure==
	[[4ai5]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_mssa476 Staphylococcus aureus subsp. aureus mssa476]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AI5 OCA].		[[4ai5]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_mssa476 Staphylococcus aureus subsp. aureus mssa476]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AI5 OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:022684054</ref><references group="xtra"/>
	[[Category: DNA-3-methyladenine glycosylase I]]		[[Category: DNA-3-methyladenine glycosylase I]]
	[[Category: Staphylococcus aureus subsp. aureus mssa476]]		[[Category: Staphylococcus aureus subsp. aureus mssa476]]

OCA at 05:18, 13 June 2012

OCA — Wed, 13 Jun 2012 05:18:22 GMT

←Older revision		Revision as of 05:18, 13 June 2012
Line 1:		Line 1:
-	[[Image:4ai5.~~jpg~~\|left\|200px]]	+	[[Image:4ai5.png\|left\|200px]]

	<!--		<!--

OCA: Protected "4ai5" [edit=sysop:move=sysop]

OCA — Wed, 15 Feb 2012 06:57:16 GMT

Protected "4ai5" [edit=sysop:move=sysop]

←Older revision

Revision as of 06:57, 15 February 2012