4ajc - Revision history

OCA at 11:28, 20 December 2023

OCA — Wed, 20 Dec 2023 11:28:30 GMT

←Older revision		Revision as of 11:28, 20 December 2023
Line 3:		Line 3:
	<StructureSection load='4ajc' size='340' side='right'caption='[[4ajc]], [[Resolution\|resolution]] 2.30Å' scene=''>		<StructureSection load='4ajc' size='340' side='right'caption='[[4ajc]], [[Resolution\|resolution]] 2.30Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4ajc]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~"bacillus_coli"_migula_1895 "bacillus~~ coli~~" migula 1895~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AJC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4AJC FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4ajc]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AJC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4AJC FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A2P:ADENOSINE-2-5-DIPHOSPHATE'>A2P</scene>, <scene name='pdbligand=AKG:2-OXOGLUTARIC+ACID'>AKG</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene~~></td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.3Å</td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[4aj3\|4aj3]], [[4aja\|4aja]], [[4ajb\|4ajb]]</div></td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A2P:ADENOSINE-2-5-DIPHOSPHATE'>A2P</scene>, <scene name='pdbligand=AKG:2-OXOGLUTARIC+ACID'>AKG</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Isocitrate_dehydrogenase_(NADP(+)) Isocitrate dehydrogenase (NADP(+))], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.42 1.1.1.42] </span></td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ajc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ajc OCA], [https://pdbe.org/4ajc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ajc RCSB], [https://www.ebi.ac.uk/pdbsum/4ajc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ajc ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ajc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ajc OCA], [https://pdbe.org/4ajc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ajc RCSB], [https://www.ebi.ac.uk/pdbsum/4ajc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ajc ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/IDH_ECOLI IDH_ECOLI]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 25:		Line 26:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Bacillus~~ coli ~~migula 1895~~]]	+	[[Category: Escherichia coli]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Carrondo~~, M A~~]]	+	[[Category: Carrondo MA]]
-	[[Category: Dean~~, A M~~]]	+	[[Category: Dean AM]]
-	[[Category: Goncalves, S]]	+	[[Category: Goncalves S]]
-	[[Category: Matias~~, P M~~]]	+	[[Category: Matias PM]]
-	[[Category: Miller~~, S P]]~~	+	[[Category: Miller SP]]
-	~~[[Category: Oxidative beta-decarboxylation]]~~	+
-	~~[[Category: Oxidoreductase~~]]	+

OCA at 05:35, 25 August 2022

OCA — Thu, 25 Aug 2022 05:35:58 GMT

←Older revision		Revision as of 05:35, 25 August 2022
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	<StructureSection load='4ajc' size='340' side='right'caption='[[4ajc]], [[Resolution\|resolution]] 2.30Å' scene=''>		<StructureSection load='4ajc' size='340' side='right'caption='[[4ajc]], [[Resolution\|resolution]] 2.30Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4ajc]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AJC OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4AJC FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4ajc]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AJC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4AJC FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=A2P:ADENOSINE-2-5-DIPHOSPHATE'>A2P</scene>, <scene name='pdbligand=AKG:2-OXOGLUTARIC+ACID'>AKG</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A2P:ADENOSINE-2-5-DIPHOSPHATE'>A2P</scene>, <scene name='pdbligand=AKG:2-OXOGLUTARIC+ACID'>AKG</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4aj3\|4aj3]], [[4aja\|4aja]], [[4ajb\|4ajb]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[4aj3\|4aj3]], [[4aja\|4aja]], [[4ajb\|4ajb]]</div></td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/Isocitrate_dehydrogenase_(NADP(+)) Isocitrate dehydrogenase (NADP(+))], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.42 1.1.1.42] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Isocitrate_dehydrogenase_(NADP(+)) Isocitrate dehydrogenase (NADP(+))], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.42 1.1.1.42] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4ajc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ajc OCA], [~~http~~://pdbe.org/4ajc PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4ajc RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4ajc PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4ajc ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ajc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ajc OCA], [https://pdbe.org/4ajc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ajc RCSB], [https://www.ebi.ac.uk/pdbsum/4ajc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ajc ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 20:		Line 20:

	==See Also==		==See Also==
-	*[[Isocitrate dehydrogenase\|Isocitrate dehydrogenase]]	+	*[[Isocitrate dehydrogenase 3D structures\|Isocitrate dehydrogenase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 16:24, 28 August 2019

OCA — Wed, 28 Aug 2019 16:24:44 GMT

←Older revision		Revision as of 16:24, 28 August 2019
Line 1:		Line 1:

	==3D structure of E. coli Isocitrate Dehydrogenase K100M mutant in complex with alpha-ketoglutarate, calcium(II) and adenine nucleotide phosphate==		==3D structure of E. coli Isocitrate Dehydrogenase K100M mutant in complex with alpha-ketoglutarate, calcium(II) and adenine nucleotide phosphate==
-	<StructureSection load='4ajc' size='340' side='right' caption='[[4ajc]], [[Resolution\|resolution]] 2.30Å' scene=''>	+	<StructureSection load='4ajc' size='340' side='right'caption='[[4ajc]], [[Resolution\|resolution]] 2.30Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4ajc]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AJC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4AJC FirstGlance]. <br>		<table><tr><td colspan='2'>[[4ajc]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AJC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4AJC FirstGlance]. <br>
Line 18:		Line 18:
	</div>		</div>
	<div class="pdbe-citations 4ajc" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 4ajc" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Isocitrate dehydrogenase\|Isocitrate dehydrogenase]]
	== References ==		== References ==
	<references/>		<references/>
Line 23:		Line 26:
	</StructureSection>		</StructureSection>
	[[Category: Bacillus coli migula 1895]]		[[Category: Bacillus coli migula 1895]]
		+	[[Category: Large Structures]]
	[[Category: Carrondo, M A]]		[[Category: Carrondo, M A]]
	[[Category: Dean, A M]]		[[Category: Dean, A M]]

OCA at 07:41, 16 November 2017

OCA — Thu, 16 Nov 2017 07:41:26 GMT

←Older revision		Revision as of 07:41, 16 November 2017
Line 18:		Line 18:
	</div>		</div>
	<div class="pdbe-citations 4ajc" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 4ajc" style="background-color:#fffaf0;"></div>
-
-	==See Also==
-	*[[Isocitrate dehydrogenase\|Isocitrate dehydrogenase]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 12:36, 11 August 2016

OCA — Thu, 11 Aug 2016 12:36:56 GMT

←Older revision		Revision as of 12:36, 11 August 2016
Line 1:		Line 1:
		+
	==3D structure of E. coli Isocitrate Dehydrogenase K100M mutant in complex with alpha-ketoglutarate, calcium(II) and adenine nucleotide phosphate==		==3D structure of E. coli Isocitrate Dehydrogenase K100M mutant in complex with alpha-ketoglutarate, calcium(II) and adenine nucleotide phosphate==
	<StructureSection load='4ajc' size='340' side='right' caption='[[4ajc]], [[Resolution\|resolution]] 2.30Å' scene=''>		<StructureSection load='4ajc' size='340' side='right' caption='[[4ajc]], [[Resolution\|resolution]] 2.30Å' scene=''>
Line 6:		Line 7:
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4aj3\|4aj3]], [[4aja\|4aja]], [[4ajb\|4ajb]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4aj3\|4aj3]], [[4aja\|4aja]], [[4ajb\|4ajb]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Isocitrate_dehydrogenase_(NADP(+)) Isocitrate dehydrogenase (NADP(+))], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.42 1.1.1.42] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Isocitrate_dehydrogenase_(NADP(+)) Isocitrate dehydrogenase (NADP(+))], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.42 1.1.1.42] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ajc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ajc OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4ajc RCSB], [http://www.ebi.ac.uk/pdbsum/4ajc PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ajc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ajc OCA], [http://pdbe.org/4ajc PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4ajc RCSB], [http://www.ebi.ac.uk/pdbsum/4ajc PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4ajc ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 16:		Line 17:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 4ajc" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==

OCA at 09:24, 4 January 2015

OCA — Sun, 04 Jan 2015 09:24:26 GMT

←Older revision		Revision as of 09:24, 4 January 2015
Line 1:		Line 1:
-	[[~~Image:~~4ajc.~~jpg~~\|~~left~~\|~~200px~~]]	+	==3D structure of E. coli Isocitrate Dehydrogenase K100M mutant in complex with alpha-ketoglutarate, calcium(II) and adenine nucleotide phosphate==
		+	<StructureSection load='4ajc' size='340' side='right' caption='[[4ajc]], [[Resolution\|resolution]] 2.30Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[4ajc]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AJC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4AJC FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=A2P:ADENOSINE-2-5-DIPHOSPHATE'>A2P</scene>, <scene name='pdbligand=AKG:2-OXOGLUTARIC+ACID'>AKG</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4aj3\|4aj3]], [[4aja\|4aja]], [[4ajb\|4ajb]]</td></tr>
		+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Isocitrate_dehydrogenase_(NADP(+)) Isocitrate dehydrogenase (NADP(+))], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.42 1.1.1.42] </span></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ajc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ajc OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4ajc RCSB], [http://www.ebi.ac.uk/pdbsum/4ajc PDBsum]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	NADP(+) dependent isocitrate dehydrogenase (IDH; EC 1.1.1.42) belongs to a large family of alpha-hydroxyacid oxidative beta-decarboxylases that catalyze similar three-step reactions, with dehydrogenation to an oxaloacid intermediate preceding beta-decarboxylation to an enol intermediate followed by tautomerization to the final alpha-ketone product. A comprehensive view of the induced fit needed for catalysis is revealed on comparing the first "fully closed" crystal structures of a pseudo-Michaelis complex of wild-type Escherichia coli IDH (EcoIDH) and the "fully closed" reaction product complex of the K100M mutant with previously obtained "quasi-closed" and "open" conformations. Conserved catalytic residues, binding the nicotinamide ring of NADP(+) and the metal-bound substrate, move as rigid bodies during domain closure by a hinge motion that spans the central beta-sheet in each monomer. Interactions established between Thr105 and Ser113, which flank the "phosphorylation loop", and the nicotinamide mononucleotide moiety of NADP(+) establish productive coenzyme binding. Electrostatic interactions of a Lys100-Leu103-Asn115-Glu336 tetrad play a pivotal role in assembling a catalytically competent active site. As predicted, Lys230* is positioned to deprotonate/reprotonate the alpha-hydroxyl in both reaction steps and Tyr160 moves into position to protonate C3 following beta-decarboxylation. A proton relay from the catalytic triad Tyr160-Asp307-Lys230* connects the alpha-hydroxyl of isocitrate to the bulk solvent to complete the picture of the catalytic mechanism.

-	~~{{STRUCTURE_4ajc\| PDB=4ajc \| SCENE= }}~~	+	Induced fit and the catalytic mechanism of isocitrate dehydrogenase.,Goncalves S, Miller SP, Carrondo MA, Dean AM, Matias PM Biochemistry. 2012 Sep 11;51(36):7098-115. Epub 2012 Aug 27. PMID:22891681<ref>PMID:22891681</ref>

-	~~===3D structure~~ of E. ~~coli Isocitrate Dehydrogenase K100M mutant in complex with alpha-ketoglutarate, calcium(II) and adenine nucleotide phosphate===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>

-	~~{{ABSTRACT_PUBMED_22891681}}~~	+	==See Also==
-		+	*[[Isocitrate dehydrogenase\|Isocitrate dehydrogenase]]
-	==~~About this Structure~~==	+	== References ==
-	[[~~4ajc~~]] ~~is a 1 chain structure with sequence from [http:~~//~~en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AJC OCA].~~	+	<references/>
-	[[Category: ~~Escherichia~~ coli]]	+	__TOC__
-	[[Category: Carrondo, M A.]]	+	</StructureSection>
-	[[Category: Dean, A M.]]	+	[[Category: Bacillus coli migula 1895]]
-	[[Category: Goncalves, S.]]	+	[[Category: Carrondo, M A]]
-	[[Category: Matias, P M.]]	+	[[Category: Dean, A M]]
-	[[Category: Miller, S P.]]	+	[[Category: Goncalves, S]]
		+	[[Category: Matias, P M]]
		+	[[Category: Miller, S P]]
	[[Category: Oxidative beta-decarboxylation]]		[[Category: Oxidative beta-decarboxylation]]
	[[Category: Oxidoreductase]]		[[Category: Oxidoreductase]]

OCA at 09:12, 31 October 2012

OCA — Wed, 31 Oct 2012 09:12:06 GMT

←Older revision		Revision as of 09:12, 31 October 2012
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	[[Image:4ajc.jpg\|left\|200px]]

-	~~The entry~~ 4ajc ~~is ON HOLD~~ ~~until Paper Publication~~	+	{{STRUCTURE_4ajc\| PDB=4ajc \| SCENE= }}

-	~~Authors: Goncalves, S~~., ~~Miller, S.P., Carrondo, M.A., Dean, A.M., Matias, P.M.~~	+	===3D structure of E. coli Isocitrate Dehydrogenase K100M mutant in complex with alpha-ketoglutarate, calcium(II) and adenine nucleotide phosphate===

-	~~Description: 3D~~ structure ~~of E~~. coli ~~Isocitrate Dehydrogenase K100M mutant in complex with alpha~~-~~ketoglutarate~~, ~~calcium(II) and adenine nucleotide phosphate~~	+	{{ABSTRACT_PUBMED_22891681}}
		+
		+	==About this Structure==
		+	[[4ajc]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AJC OCA].
		+	[[Category: Escherichia coli]]
		+	[[Category: Carrondo, M A.]]
		+	[[Category: Dean, A M.]]
		+	[[Category: Goncalves, S.]]
		+	[[Category: Matias, P M.]]
		+	[[Category: Miller, S P.]]
		+	[[Category: Oxidative beta-decarboxylation]]
		+	[[Category: Oxidoreductase]]

OCA at 08:19, 29 February 2012

OCA — Wed, 29 Feb 2012 08:19:40 GMT

←Older revision		Revision as of 08:19, 29 February 2012
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 4ajc is ON HOLD	+	The entry 4ajc is ON HOLD until Paper Publication

	Authors: Goncalves, S., Miller, S.P., Carrondo, M.A., Dean, A.M., Matias, P.M.		Authors: Goncalves, S., Miller, S.P., Carrondo, M.A., Dean, A.M., Matias, P.M.

	Description: 3D structure of E. coli Isocitrate Dehydrogenase K100M mutant in complex with alpha-ketoglutarate, calcium(II) and adenine nucleotide phosphate		Description: 3D structure of E. coli Isocitrate Dehydrogenase K100M mutant in complex with alpha-ketoglutarate, calcium(II) and adenine nucleotide phosphate

OCA: Protected "4ajc" [edit=sysop:move=sysop]

OCA — Wed, 22 Feb 2012 07:26:25 GMT

Protected "4ajc" [edit=sysop:move=sysop]

←Older revision

Revision as of 07:26, 22 February 2012

OCA: New page: '''Unreleased structure''' The entry 4ajc is ON HOLD Authors: Goncalves, S., Miller, S.P., Carrondo, M.A., Dean, A.M., Matias, P.M. Description: 3D structure of E. coli Isocitrate Dehy...

OCA — Wed, 22 Feb 2012 07:26:24 GMT

New page: '''Unreleased structure''' The entry 4ajc is ON HOLD Authors: Goncalves, S., Miller, S.P., Carrondo, M.A., Dean, A.M., Matias, P.M. Description: 3D structure of E. coli Isocitrate Dehy...

New page

'''Unreleased structure'''

The entry 4ajc is ON HOLD

Authors: Goncalves, S., Miller, S.P., Carrondo, M.A., Dean, A.M., Matias, P.M.

Description: 3D structure of E. coli Isocitrate Dehydrogenase K100M mutant in complex with alpha-ketoglutarate, calcium(II) and adenine nucleotide phosphate