4ard - Revision history

OCA at 10:53, 9 May 2024

OCA — Thu, 09 May 2024 10:53:29 GMT

←Older revision		Revision as of 10:53, 9 May 2024
Line 3:		Line 3:
	<SX load='4ard' size='340' side='right' viewer='molstar' caption='[[4ard]], [[Resolution\|resolution]] 7.00Å' scene=''>		<SX load='4ard' size='340' side='right' viewer='molstar' caption='[[4ard]], [[Resolution\|resolution]] 7.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4ard]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Mpmv Mpmv~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ARD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4ARD FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4ard]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mason-Pfizer_monkey_virus Mason-Pfizer monkey virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ARD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4ARD FirstGlance]. <br>
-	</td></tr><tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"~~><div style~~=~~'overflow: auto; max-height: 3em;'~~>~~[[1bax\|1bax]]~~, [[~~1cl4~~\|~~1cl4~~]]~~, [[4arg\|4arg]]</div>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution\|Resolution]] 7Å</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ard FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ard OCA], [https://pdbe.org/4ard PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ard RCSB], [https://www.ebi.ac.uk/pdbsum/4ard PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ard ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ard FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ard OCA], [https://pdbe.org/4ard PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ard RCSB], [https://www.ebi.ac.uk/pdbsum/4ard PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ard ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/GAG_MPMV GAG_MPMV]] p10 is the matrix protein. P14 is the nucleocapsid protein. p27 is the capsid protein.	+	[https://www.uniprot.org/uniprot/GAG_MPMV GAG_MPMV] p10 is the matrix protein. P14 is the nucleocapsid protein. p27 is the capsid protein.
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 26:		Line 26:
	</SX>		</SX>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Mpmv~~]]	+	[[Category: Mason-Pfizer monkey virus]]
-	[[Category: Bharat~~, T A.M~~]]	+	[[Category: Bharat TAM]]
-	[[Category: Briggs~~, J A.G~~]]	+	[[Category: Briggs JAG]]
-	[[Category: Davey~~, N E~~]]	+	[[Category: Davey NE]]
-	[[Category: Marco~~, A D~~]]	+	[[Category: Marco AD]]
-	[[Category: Riches~~, J D~~]]	+	[[Category: Riches JD]]
-	[[Category: Ruml, T]]	+	[[Category: Ruml T]]
-	[[Category: Rumlova, M]]	+	[[Category: Rumlova M]]
-	[[Category: Sachse, C]]	+	[[Category: Sachse C]]
-	[[Category: Ulbrich, P]]	+	[[Category: Ulbrich P]]
-	~~[[Category: Gag]]~~	+
-	~~[[Category: Retrovirus]]~~	+
-	~~[[Category: Viral protein~~]]	+

OCA at 05:43, 25 August 2022

OCA — Thu, 25 Aug 2022 05:43:42 GMT

←Older revision		Revision as of 05:43, 25 August 2022
Line 3:		Line 3:
	<SX load='4ard' size='340' side='right' viewer='molstar' caption='[[4ard]], [[Resolution\|resolution]] 7.00Å' scene=''>		<SX load='4ard' size='340' side='right' viewer='molstar' caption='[[4ard]], [[Resolution\|resolution]] 7.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4ard]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Mpmv Mpmv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ARD OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=4ARD FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4ard]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mpmv Mpmv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ARD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4ARD FirstGlance]. <br>
-	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1bax\|1bax]], [[1cl4\|1cl4]], [[4arg\|4arg]]</td></tr>	+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1bax\|1bax]], [[1cl4\|1cl4]], [[4arg\|4arg]]</div></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=4ard FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ard OCA], [~~http~~://pdbe.org/4ard PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4ard RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4ard PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4ard ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ard FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ard OCA], [https://pdbe.org/4ard PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ard RCSB], [https://www.ebi.ac.uk/pdbsum/4ard PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ard ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/GAG_MPMV GAG_MPMV]] p10 is the matrix protein. P14 is the nucleocapsid protein. p27 is the capsid protein.	+	[[https://www.uniprot.org/uniprot/GAG_MPMV GAG_MPMV]] p10 is the matrix protein. P14 is the nucleocapsid protein. p27 is the capsid protein.
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==

OCA at 18:51, 10 April 2020

OCA — Fri, 10 Apr 2020 18:51:53 GMT

←Older revision		Revision as of 18:51, 10 April 2020
Line 3:		Line 3:
	<SX load='4ard' size='340' side='right' viewer='molstar' caption='[[4ard]], [[Resolution\|resolution]] 7.00Å' scene=''>		<SX load='4ard' size='340' side='right' viewer='molstar' caption='[[4ard]], [[Resolution\|resolution]] 7.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4ard]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mpmv Mpmv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ARD OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4ARD FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4ard]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mpmv Mpmv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ARD OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=4ARD FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1bax\|1bax]], [[1cl4\|1cl4]], [[4arg\|4arg]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1bax\|1bax]], [[1cl4\|1cl4]], [[4arg\|4arg]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4ard FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ard OCA], [http://pdbe.org/4ard PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4ard RCSB], [http://www.ebi.ac.uk/pdbsum/4ard PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4ard ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=4ard FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ard OCA], [http://pdbe.org/4ard PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4ard RCSB], [http://www.ebi.ac.uk/pdbsum/4ard PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4ard ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 20:		Line 20:

	==See Also==		==See Also==
-	*[[Virus coat ~~protein~~\|Virus coat ~~protein~~]]	+	*[[Virus coat proteins 3D structures\|Virus coat proteins 3D structures]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 17:48, 6 March 2020

OCA — Fri, 06 Mar 2020 17:48:43 GMT

←Older revision		Revision as of 17:48, 6 March 2020
Line 1:		Line 1:

	==Structure of the immature retroviral capsid at 8A resolution by cryo- electron microscopy==		==Structure of the immature retroviral capsid at 8A resolution by cryo- electron microscopy==
-	<~~StructureSection~~ load='4ard' size='340' side='right'caption='[[4ard]], [[Resolution\|resolution]] 7.00Å' scene=''>	+	<SX load='4ard' size='340' side='right' viewer='molstar' caption='[[4ard]], [[Resolution\|resolution]] 7.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4ard]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mpmv Mpmv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ARD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ARD FirstGlance]. <br>		<table><tr><td colspan='2'>[[4ard]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mpmv Mpmv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ARD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ARD FirstGlance]. <br>
Line 24:		Line 24:
	<references/>		<references/>
	__TOC__		__TOC__
-	</~~StructureSection~~>	+	</SX>
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Mpmv]]		[[Category: Mpmv]]

OCA at 07:24, 24 April 2019

OCA — Wed, 24 Apr 2019 07:24:49 GMT

←Older revision		Revision as of 07:24, 24 April 2019
Line 25:		Line 25:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Mpmv]]		[[Category: Mpmv]]
	[[Category: Bharat, T A.M]]		[[Category: Bharat, T A.M]]

OCA at 08:56, 6 March 2019

OCA — Wed, 06 Mar 2019 08:56:56 GMT

←Older revision		Revision as of 08:56, 6 March 2019
Line 1:		Line 1:

	==Structure of the immature retroviral capsid at 8A resolution by cryo- electron microscopy==		==Structure of the immature retroviral capsid at 8A resolution by cryo- electron microscopy==
-	<StructureSection load='4ard' size='340' side='right' caption='[[4ard]], [[Resolution\|resolution]] 7.00Å' scene=''>	+	<StructureSection load='4ard' size='340' side='right'caption='[[4ard]], [[Resolution\|resolution]] 7.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4ard]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ARD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ARD FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4ard]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mpmv Mpmv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ARD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ARD FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1bax\|1bax]], [[1cl4\|1cl4]], [[4arg\|4arg]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1bax\|1bax]], [[1cl4\|1cl4]], [[4arg\|4arg]]</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ard FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ard OCA], [http://pdbe.org/4ard PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4ard RCSB], [http://www.ebi.ac.uk/pdbsum/4ard PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4ard ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ard FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ard OCA], [http://pdbe.org/4ard PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4ard RCSB], [http://www.ebi.ac.uk/pdbsum/4ard PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4ard ProSAT]</span></td></tr>
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Mpmv]]
	[[Category: Bharat, T A.M]]		[[Category: Bharat, T A.M]]
	[[Category: Briggs, J A.G]]		[[Category: Briggs, J A.G]]

OCA at 06:18, 19 April 2017

OCA — Wed, 19 Apr 2017 06:18:17 GMT

←Older revision		Revision as of 06:18, 19 April 2017
Line 3:		Line 3:
	<StructureSection load='4ard' size='340' side='right' caption='[[4ard]], [[Resolution\|resolution]] 7.00Å' scene=''>		<StructureSection load='4ard' size='340' side='right' caption='[[4ard]], [[Resolution\|resolution]] 7.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4ard]] is a 2 chain structure ~~with sequence from [http://en.wikipedia.org/wiki/Mpmv Mpmv]~~. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ARD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ARD FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4ard]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ARD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ARD FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1bax\|1bax]], [[1cl4\|1cl4]], [[4arg\|4arg]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1bax\|1bax]], [[1cl4\|1cl4]], [[4arg\|4arg]]</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ard FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ard OCA], [http://pdbe.org/4ard PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4ard RCSB], [http://www.ebi.ac.uk/pdbsum/4ard PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4ard ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ard FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ard OCA], [http://pdbe.org/4ard PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4ard RCSB], [http://www.ebi.ac.uk/pdbsum/4ard PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4ard ProSAT]</span></td></tr>
Line 25:		Line 25:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Mpmv]]
	[[Category: Bharat, T A.M]]		[[Category: Bharat, T A.M]]
	[[Category: Briggs, J A.G]]		[[Category: Briggs, J A.G]]

OCA at 09:31, 5 August 2016

OCA — Fri, 05 Aug 2016 09:31:30 GMT

←Older revision		Revision as of 09:31, 5 August 2016
Line 1:		Line 1:
		+
	==Structure of the immature retroviral capsid at 8A resolution by cryo- electron microscopy==		==Structure of the immature retroviral capsid at 8A resolution by cryo- electron microscopy==
	<StructureSection load='4ard' size='340' side='right' caption='[[4ard]], [[Resolution\|resolution]] 7.00Å' scene=''>		<StructureSection load='4ard' size='340' side='right' caption='[[4ard]], [[Resolution\|resolution]] 7.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4ard]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Mason-pfizer_monkey_virus Mason-pfizer monkey virus~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ARD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ARD FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4ard]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mpmv Mpmv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ARD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ARD FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1bax\|1bax]], [[1cl4\|1cl4]], [[4arg\|4arg]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1bax\|1bax]], [[1cl4\|1cl4]], [[4arg\|4arg]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ard FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ard OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4ard RCSB], [http://www.ebi.ac.uk/pdbsum/4ard PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ard FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ard OCA], [http://pdbe.org/4ard PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4ard RCSB], [http://www.ebi.ac.uk/pdbsum/4ard PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4ard ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 16:		Line 17:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 4ard" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 23:		Line 25:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Mason-pfizer monkey virus~~]]	+	[[Category: Mpmv]]
	[[Category: Bharat, T A.M]]		[[Category: Bharat, T A.M]]
	[[Category: Briggs, J A.G]]		[[Category: Briggs, J A.G]]

OCA at 01:12, 25 December 2014

OCA — Thu, 25 Dec 2014 01:12:57 GMT

←Older revision		Revision as of 01:12, 25 December 2014
Line 1:		Line 1:
-	[[~~Image:~~4ard.~~png~~\|~~left~~\|~~200px~~]]	+	==Structure of the immature retroviral capsid at 8A resolution by cryo- electron microscopy==
		+	<StructureSection load='4ard' size='340' side='right' caption='[[4ard]], [[Resolution\|resolution]] 7.00Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[4ard]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mason-pfizer_monkey_virus Mason-pfizer monkey virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ARD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ARD FirstGlance]. <br>
		+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1bax\|1bax]], [[1cl4\|1cl4]], [[4arg\|4arg]]</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ard FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ard OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4ard RCSB], [http://www.ebi.ac.uk/pdbsum/4ard PDBsum]</span></td></tr>
		+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/GAG_MPMV GAG_MPMV]] p10 is the matrix protein. P14 is the nucleocapsid protein. p27 is the capsid protein.
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The assembly of retroviruses such as HIV-1 is driven by oligomerization of their major structural protein, Gag. Gag is a multidomain polyprotein including three conserved folded domains: MA (matrix), CA (capsid) and NC (nucleocapsid). Assembly of an infectious virion proceeds in two stages. In the first stage, Gag oligomerization into a hexameric protein lattice leads to the formation of an incomplete, roughly spherical protein shell that buds through the plasma membrane of the infected cell to release an enveloped immature virus particle. In the second stage, cleavage of Gag by the viral protease leads to rearrangement of the particle interior, converting the non-infectious immature virus particle into a mature infectious virion. The immature Gag shell acts as the pivotal intermediate in assembly and is a potential target for anti-retroviral drugs both in inhibiting virus assembly and in disrupting virus maturation. However, detailed structural information on the immature Gag shell has not previously been available. For this reason it is unclear what protein conformations and interfaces mediate the interactions between domains and therefore the assembly of retrovirus particles, and what structural transitions are associated with retrovirus maturation. Here we solve the structure of the immature retroviral Gag shell from Mason-Pfizer monkey virus by combining cryo-electron microscopy and tomography. The 8-A resolution structure permits the derivation of a pseudo-atomic model of CA in the immature retrovirus, which defines the protein interfaces mediating retrovirus assembly. We show that transition of an immature retrovirus into its mature infectious form involves marked rotations and translations of CA domains, that the roles of the amino-terminal and carboxy-terminal domains of CA in assembling the immature and mature hexameric lattices are exchanged, and that the CA interactions that stabilize the immature and mature viruses are almost completely distinct.

-	~~{{STRUCTURE_4ard\| PDB=4ard \| SCENE= }}~~	+	Structure of the immature retroviral capsid at 8 A resolution by cryo-electron microscopy.,Bharat TA, Davey NE, Ulbrich P, Riches JD, de Marco A, Rumlova M, Sachse C, Ruml T, Briggs JA Nature. 2012 Jul 19;487(7407):385-9. PMID:22722831<ref>PMID:22722831</ref>

-	~~===Structure~~ of the ~~immature retroviral capsid at 8A resolution by cryo- electron microscopy===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_22722831}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[4ard]] is a 2 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Mason-pfizer_monkey_virus Mason-pfizer monkey virus]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=4ARD OCA].~~	+

	==See Also==		==See Also==
	*[[Virus coat protein\|Virus coat protein]]		*[[Virus coat protein\|Virus coat protein]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	<~~ref group="xtra">PMID:022722831<~~/~~ref~~><~~references group="xtra"~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Mason-pfizer monkey virus]]		[[Category: Mason-pfizer monkey virus]]
-	[[Category: Bharat, T A.M.]]	+	[[Category: Bharat, T A.M]]
-	[[Category: Briggs, J A.G.]]	+	[[Category: Briggs, J A.G]]
-	[[Category: Davey, N E.]]	+	[[Category: Davey, N E]]
-	[[Category: Marco, A D.]]	+	[[Category: Marco, A D]]
-	[[Category: Riches, J D.]]	+	[[Category: Riches, J D]]
-	[[Category: Ruml, T.]]	+	[[Category: Ruml, T]]
-	[[Category: Rumlova, M.]]	+	[[Category: Rumlova, M]]
-	[[Category: Sachse, C.]]	+	[[Category: Sachse, C]]
-	[[Category: Ulbrich, P.]]	+	[[Category: Ulbrich, P]]
	[[Category: Gag]]		[[Category: Gag]]
	[[Category: Retrovirus]]		[[Category: Retrovirus]]
	[[Category: Viral protein]]		[[Category: Viral protein]]

OCA at 11:00, 20 October 2012

OCA — Sat, 20 Oct 2012 11:00:54 GMT

←Older revision		Revision as of 11:00, 20 October 2012
Line 9:		Line 9:
	==About this Structure==		==About this Structure==
	[[4ard]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mason-pfizer_monkey_virus Mason-pfizer monkey virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ARD OCA].		[[4ard]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mason-pfizer_monkey_virus Mason-pfizer monkey virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ARD OCA].
		+
		+	==See Also==
		+	*[[Virus coat protein\|Virus coat protein]]

	==Reference==		==Reference==