4asi - Revision history

OCA at 11:34, 20 December 2023

OCA — Wed, 20 Dec 2023 11:34:44 GMT

←Older revision		Revision as of 11:34, 20 December 2023
Line 3:		Line 3:
	<StructureSection load='4asi' size='340' side='right'caption='[[4asi]], [[Resolution\|resolution]] 2.80Å' scene=''>		<StructureSection load='4asi' size='340' side='right'caption='[[4asi]], [[Resolution\|resolution]] 2.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4asi]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Human Human~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ASI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4ASI FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4asi]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ASI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4ASI FirstGlance]. <br>
-	</td></tr><tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat">~~<div style='overflow: auto; max~~-~~height: 3em;'>~~[[~~2yl2~~\|~~2yl2~~]]~~</div>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.8Å</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4asi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4asi OCA], [https://pdbe.org/4asi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4asi RCSB], [https://www.ebi.ac.uk/pdbsum/4asi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4asi ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4asi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4asi OCA], [https://pdbe.org/4asi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4asi RCSB], [https://www.ebi.ac.uk/pdbsum/4asi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4asi ProSAT]</span></td></tr>
	</table>		</table>
	== Disease ==		== Disease ==
-	[[https://www.uniprot.org/uniprot/ACACA_HUMAN ACACA_HUMAN]] Defects in ACACA are a cause of acetyl-CoA carboxylase 1 deficiency (ACACAD) [MIM:[https://omim.org/entry/613933 613933]]; also known as ACAC deficiency or ACC deficiency. An inborn error of de novo fatty acid synthesis associated with severe brain damage, persistent myopathy and poor growth.<ref>PMID:6114432</ref>	+	[https://www.uniprot.org/uniprot/ACACA_HUMAN ACACA_HUMAN] Defects in ACACA are a cause of acetyl-CoA carboxylase 1 deficiency (ACACAD) [MIM:[https://omim.org/entry/613933 613933]; also known as ACAC deficiency or ACC deficiency. An inborn error of de novo fatty acid synthesis associated with severe brain damage, persistent myopathy and poor growth.<ref>PMID:6114432</ref>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/ACACA_HUMAN ACACA_HUMAN]] Catalyzes the rate-limiting reaction in the biogenesis of long-chain fatty acids. Carries out three functions: biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase.<ref>PMID:20952656</ref>	+	[https://www.uniprot.org/uniprot/ACACA_HUMAN ACACA_HUMAN] Catalyzes the rate-limiting reaction in the biogenesis of long-chain fatty acids. Carries out three functions: biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase.<ref>PMID:20952656</ref>

	==See Also==		==See Also==
Line 18:		Line 18:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Human~~]]	+	[[Category: Homo sapiens]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Arrowsmith~~, C H~~]]	+	[[Category: Arrowsmith CH]]
-	[[Category: Bountra, C]]	+	[[Category: Bountra C]]
-	~~[[Category: Delft, F von~~]]	+	[[Category: Edwards A]]
-	[[Category: Edwards, A]]	+	[[Category: Froese DS]]
-	[[Category: Froese~~, D S~~]]	+	[[Category: Kiyani W]]
-	[[Category: Kiyani, W]]	+	[[Category: Krojer T]]
-	[[Category: Krojer, T]]	+	[[Category: Muniz JRC]]
-	[[Category: Muniz~~, J R.C~~]]	+	[[Category: Oppermann U]]
-	[[Category: Oppermann, U]]	+	[[Category: Vollmar M]]
-	[[Category: Vollmar, M]]	+	[[Category: Yue WW]]
-	[[Category: Yue~~, W W~~]]	+	[[Category: Von Delft F]]
-	[[Category: ~~Ligase]]~~	+
-	~~[[Category: Protein~~]]	+

OCA at 05:44, 25 August 2022

OCA — Thu, 25 Aug 2022 05:44:51 GMT

←Older revision		Revision as of 05:44, 25 August 2022
Line 3:		Line 3:
	<StructureSection load='4asi' size='340' side='right'caption='[[4asi]], [[Resolution\|resolution]] 2.80Å' scene=''>		<StructureSection load='4asi' size='340' side='right'caption='[[4asi]], [[Resolution\|resolution]] 2.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4asi]] is a 6 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ASI OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4ASI FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4asi]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ASI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4ASI FirstGlance]. <br>
-	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2yl2\|2yl2]]</td></tr>	+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2yl2\|2yl2]]</div></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4asi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4asi OCA], [~~http~~://pdbe.org/4asi PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4asi RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4asi PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4asi ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4asi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4asi OCA], [https://pdbe.org/4asi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4asi RCSB], [https://www.ebi.ac.uk/pdbsum/4asi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4asi ProSAT]</span></td></tr>
	</table>		</table>
	== Disease ==		== Disease ==
-	[[~~http~~://www.uniprot.org/uniprot/ACACA_HUMAN ACACA_HUMAN]] Defects in ACACA are a cause of acetyl-CoA carboxylase 1 deficiency (ACACAD) [MIM:[~~http~~://omim.org/entry/613933 613933]]; also known as ACAC deficiency or ACC deficiency. An inborn error of de novo fatty acid synthesis associated with severe brain damage, persistent myopathy and poor growth.<ref>PMID:6114432</ref>	+	[[https://www.uniprot.org/uniprot/ACACA_HUMAN ACACA_HUMAN]] Defects in ACACA are a cause of acetyl-CoA carboxylase 1 deficiency (ACACAD) [MIM:[https://omim.org/entry/613933 613933]]; also known as ACAC deficiency or ACC deficiency. An inborn error of de novo fatty acid synthesis associated with severe brain damage, persistent myopathy and poor growth.<ref>PMID:6114432</ref>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/ACACA_HUMAN ACACA_HUMAN]] Catalyzes the rate-limiting reaction in the biogenesis of long-chain fatty acids. Carries out three functions: biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase.<ref>PMID:20952656</ref>	+	[[https://www.uniprot.org/uniprot/ACACA_HUMAN ACACA_HUMAN]] Catalyzes the rate-limiting reaction in the biogenesis of long-chain fatty acids. Carries out three functions: biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase.<ref>PMID:20952656</ref>

	==See Also==		==See Also==

OCA at 16:58, 29 January 2020

OCA — Wed, 29 Jan 2020 16:58:46 GMT

←Older revision		Revision as of 16:58, 29 January 2020
Line 1:		Line 1:

	==Crystal structure of human ACACA C-terminal domain==		==Crystal structure of human ACACA C-terminal domain==
-	<StructureSection load='4asi' size='340' side='right' caption='[[4asi]], [[Resolution\|resolution]] 2.80Å' scene=''>	+	<StructureSection load='4asi' size='340' side='right'caption='[[4asi]], [[Resolution\|resolution]] 2.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4asi]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ASI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ASI FirstGlance]. <br>		<table><tr><td colspan='2'>[[4asi]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ASI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ASI FirstGlance]. <br>
Line 11:		Line 11:
	== Function ==		== Function ==
	[[http://www.uniprot.org/uniprot/ACACA_HUMAN ACACA_HUMAN]] Catalyzes the rate-limiting reaction in the biogenesis of long-chain fatty acids. Carries out three functions: biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase.<ref>PMID:20952656</ref>		[[http://www.uniprot.org/uniprot/ACACA_HUMAN ACACA_HUMAN]] Catalyzes the rate-limiting reaction in the biogenesis of long-chain fatty acids. Carries out three functions: biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase.<ref>PMID:20952656</ref>
		+
		+	==See Also==
		+	*[[Acetyl-CoA carboxylase 3D structures\|Acetyl-CoA carboxylase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 16:		Line 19:
	</StructureSection>		</StructureSection>
	[[Category: Human]]		[[Category: Human]]
		+	[[Category: Large Structures]]
	[[Category: Arrowsmith, C H]]		[[Category: Arrowsmith, C H]]
	[[Category: Bountra, C]]		[[Category: Bountra, C]]

OCA at 19:45, 24 January 2018

OCA — Wed, 24 Jan 2018 19:45:37 GMT

←Older revision		Revision as of 19:45, 24 January 2018
Line 11:		Line 11:
	== Function ==		== Function ==
	[[http://www.uniprot.org/uniprot/ACACA_HUMAN ACACA_HUMAN]] Catalyzes the rate-limiting reaction in the biogenesis of long-chain fatty acids. Carries out three functions: biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase.<ref>PMID:20952656</ref>		[[http://www.uniprot.org/uniprot/ACACA_HUMAN ACACA_HUMAN]] Catalyzes the rate-limiting reaction in the biogenesis of long-chain fatty acids. Carries out three functions: biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase.<ref>PMID:20952656</ref>
-
-	==See Also==
-	*[[Acetyl-CoA carboxylase\|Acetyl-CoA carboxylase]]
	== References ==		== References ==
	<references/>		<references/>
Line 21:		Line 18:
	[[Category: Arrowsmith, C H]]		[[Category: Arrowsmith, C H]]
	[[Category: Bountra, C]]		[[Category: Bountra, C]]
-	[[Category: Delft, F ~~Von~~]]	+	[[Category: Delft, F von]]
	[[Category: Edwards, A]]		[[Category: Edwards, A]]
	[[Category: Froese, D S]]		[[Category: Froese, D S]]

OCA at 14:49, 5 August 2016

OCA — Fri, 05 Aug 2016 14:49:04 GMT

←Older revision		Revision as of 14:49, 5 August 2016
Line 1:		Line 1:
		+
	==Crystal structure of human ACACA C-terminal domain==		==Crystal structure of human ACACA C-terminal domain==
	<StructureSection load='4asi' size='340' side='right' caption='[[4asi]], [[Resolution\|resolution]] 2.80Å' scene=''>		<StructureSection load='4asi' size='340' side='right' caption='[[4asi]], [[Resolution\|resolution]] 2.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4asi]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Homo_sapiens Homo sapiens~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ASI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ASI FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4asi]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ASI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ASI FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2yl2\|2yl2]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2yl2\|2yl2]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4asi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4asi OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4asi RCSB], [http://www.ebi.ac.uk/pdbsum/4asi PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4asi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4asi OCA], [http://pdbe.org/4asi PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4asi RCSB], [http://www.ebi.ac.uk/pdbsum/4asi PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4asi ProSAT]</span></td></tr>
	</table>		</table>
	== Disease ==		== Disease ==
Line 10:		Line 11:
	== Function ==		== Function ==
	[[http://www.uniprot.org/uniprot/ACACA_HUMAN ACACA_HUMAN]] Catalyzes the rate-limiting reaction in the biogenesis of long-chain fatty acids. Carries out three functions: biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase.<ref>PMID:20952656</ref>		[[http://www.uniprot.org/uniprot/ACACA_HUMAN ACACA_HUMAN]] Catalyzes the rate-limiting reaction in the biogenesis of long-chain fatty acids. Carries out three functions: biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase.<ref>PMID:20952656</ref>
		+
		+	==See Also==
		+	*[[Acetyl-CoA carboxylase\|Acetyl-CoA carboxylase]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Homo sapiens~~]]	+	[[Category: Human]]
	[[Category: Arrowsmith, C H]]		[[Category: Arrowsmith, C H]]
	[[Category: Bountra, C]]		[[Category: Bountra, C]]

OCA at 09:28, 21 December 2014

OCA — Sun, 21 Dec 2014 09:28:18 GMT

←Older revision		Revision as of 09:28, 21 December 2014
Line 1:		Line 1:
-	~~{{STRUCTURE_4asi\| PDB=4asi \| SCENE= }}~~	+	==Crystal structure of human ACACA C-terminal domain==
-	===Crystal structure of human ACACA C-terminal domain===	+	<StructureSection load='4asi' size='340' side='right' caption='[[4asi]], [[Resolution\|resolution]] 2.80Å' scene=''>
-		+	== Structural highlights ==
-	==Disease==	+	<table><tr><td colspan='2'>[[4asi]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ASI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ASI FirstGlance]. <br>
-	[[http://www.uniprot.org/uniprot/ACACA_HUMAN ACACA_HUMAN]] Defects in ACACA are a cause of acetyl-CoA carboxylase 1 deficiency (ACACAD) [MIM:[http://omim.org/entry/613933 613933]]; also known as ACAC deficiency or ACC deficiency. An inborn error of de novo fatty acid synthesis associated with severe brain damage, persistent myopathy and poor growth.<ref>PMID:6114432</ref>	+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2yl2\|2yl2]]</td></tr>
-		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4asi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4asi OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4asi RCSB], [http://www.ebi.ac.uk/pdbsum/4asi PDBsum]</span></td></tr>
-	==Function==	+	</table>
-	[[http://www.uniprot.org/uniprot/ACACA_HUMAN ACACA_HUMAN]] Catalyzes the rate-limiting reaction in the biogenesis of long-chain fatty acids. Carries out three functions: biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase.<ref>PMID:20952656</ref>	+	== Disease ==
-		+	[[http://www.uniprot.org/uniprot/ACACA_HUMAN ACACA_HUMAN]] Defects in ACACA are a cause of acetyl-CoA carboxylase 1 deficiency (ACACAD) [MIM:[http://omim.org/entry/613933 613933]]; also known as ACAC deficiency or ACC deficiency. An inborn error of de novo fatty acid synthesis associated with severe brain damage, persistent myopathy and poor growth.<ref>PMID:6114432</ref>
-	==~~About this Structure==~~	+	== Function ==
-	[[4asi]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ASI OCA].	+	[[http://www.uniprot.org/uniprot/ACACA_HUMAN ACACA_HUMAN]] Catalyzes the rate-limiting reaction in the biogenesis of long-chain fatty acids. Carries out three functions: biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase.<ref>PMID:20952656</ref>
-		+	== References ==
-	~~==Reference~~==	+	<references/>
-	<references ~~group="xtra"~~/><~~references~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Homo sapiens]]		[[Category: Homo sapiens]]
-	[[Category: Arrowsmith, C H.]]	+	[[Category: Arrowsmith, C H]]
-	[[Category: Bountra, C.]]	+	[[Category: Bountra, C]]
-	[[Category: Delft, F Von.]]	+	[[Category: Delft, F Von]]
-	[[Category: Edwards, A.]]	+	[[Category: Edwards, A]]
-	[[Category: Froese, D S.]]	+	[[Category: Froese, D S]]
-	[[Category: Kiyani, W.]]	+	[[Category: Kiyani, W]]
-	[[Category: Krojer, T.]]	+	[[Category: Krojer, T]]
-	[[Category: Muniz, J R.C.]]	+	[[Category: Muniz, J R.C]]
-	[[Category: Oppermann, U.]]	+	[[Category: Oppermann, U]]
-	[[Category: Vollmar, M.]]	+	[[Category: Vollmar, M]]
-	[[Category: Yue, W W.]]	+	[[Category: Yue, W W]]
	[[Category: Ligase]]		[[Category: Ligase]]
	[[Category: Protein]]		[[Category: Protein]]

OCA at 00:18, 25 March 2013

OCA — Mon, 25 Mar 2013 00:18:15 GMT

←Older revision		Revision as of 00:18, 25 March 2013
Line 1:		Line 1:
-	[[Image:4asi.jpg\|left\|200px]]
-
	{{STRUCTURE_4asi\| PDB=4asi \| SCENE= }}		{{STRUCTURE_4asi\| PDB=4asi \| SCENE= }}
-
	===Crystal structure of human ACACA C-terminal domain===		===Crystal structure of human ACACA C-terminal domain===

		+	==Disease==
		+	[[http://www.uniprot.org/uniprot/ACACA_HUMAN ACACA_HUMAN]] Defects in ACACA are a cause of acetyl-CoA carboxylase 1 deficiency (ACACAD) [MIM:[http://omim.org/entry/613933 613933]]; also known as ACAC deficiency or ACC deficiency. An inborn error of de novo fatty acid synthesis associated with severe brain damage, persistent myopathy and poor growth.<ref>PMID:6114432</ref>
		+
		+	==Function==
		+	[[http://www.uniprot.org/uniprot/ACACA_HUMAN ACACA_HUMAN]] Catalyzes the rate-limiting reaction in the biogenesis of long-chain fatty acids. Carries out three functions: biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase.<ref>PMID:20952656</ref>

	==About this Structure==		==About this Structure==
	[[4asi]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ASI OCA].		[[4asi]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ASI OCA].
		+
		+	==Reference==
		+	<references group="xtra"/><references/>
	[[Category: Homo sapiens]]		[[Category: Homo sapiens]]
	[[Category: Arrowsmith, C H.]]		[[Category: Arrowsmith, C H.]]

OCA at 05:20, 29 August 2012

OCA — Wed, 29 Aug 2012 05:20:26 GMT

←Older revision		Revision as of 05:20, 29 August 2012
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	[[Image:4asi.jpg\|left\|200px]]

-	~~The entry~~ 4asi ~~is ON HOLD~~	+	{{STRUCTURE_4asi\| PDB=4asi \| SCENE= }}

-	~~Authors: Froese, D.S., Muniz, J.R.~~C~~., Kiyani, W., Krojer, T., Vollmar, M., von Delft, F., Bountra, C., Arrowsmith, C.H., Edwards, A., Oppermann, U., Yue, W.W.~~	+	===Crystal structure of human ACACA C-terminal domain===

-	~~Description: Crystal~~ structure ~~of human ACACA C~~-~~terminal domain~~	+
		+	==About this Structure==
		+	[[4asi]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ASI OCA].
		+	[[Category: Homo sapiens]]
		+	[[Category: Arrowsmith, C H.]]
		+	[[Category: Bountra, C.]]
		+	[[Category: Delft, F Von.]]
		+	[[Category: Edwards, A.]]
		+	[[Category: Froese, D S.]]
		+	[[Category: Kiyani, W.]]
		+	[[Category: Krojer, T.]]
		+	[[Category: Muniz, J R.C.]]
		+	[[Category: Oppermann, U.]]
		+	[[Category: Vollmar, M.]]
		+	[[Category: Yue, W W.]]
		+	[[Category: Ligase]]
		+	[[Category: Protein]]

OCA: Protected "4asi" [edit=sysop:move=sysop]

OCA — Wed, 09 May 2012 08:42:03 GMT

Protected "4asi" [edit=sysop:move=sysop]

←Older revision

Revision as of 08:42, 9 May 2012

OCA: New page: '''Unreleased structure''' The entry 4asi is ON HOLD Authors: Froese, D.S., Muniz, J.R.C., Kiyani, W., Krojer, T., Vollmar, M., von Delft, F., Bountra, C., Arrowsmith, C.H., Edwards, A....

OCA — Wed, 09 May 2012 08:42:02 GMT

New page: '''Unreleased structure''' The entry 4asi is ON HOLD Authors: Froese, D.S., Muniz, J.R.C., Kiyani, W., Krojer, T., Vollmar, M., von Delft, F., Bountra, C., Arrowsmith, C.H., Edwards, A....

New page

'''Unreleased structure'''

The entry 4asi is ON HOLD

Authors: Froese, D.S., Muniz, J.R.C., Kiyani, W., Krojer, T., Vollmar, M., von Delft, F., Bountra, C., Arrowsmith, C.H., Edwards, A., Oppermann, U., Yue, W.W.

Description: Crystal structure of human ACACA C-terminal domain