4b0z - Revision history

OCA at 05:53, 25 August 2022

OCA — Thu, 25 Aug 2022 05:53:17 GMT

←Older revision		Revision as of 05:53, 25 August 2022
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	<StructureSection load='4b0z' size='340' side='right'caption='[[4b0z]], [[Resolution\|resolution]] 1.58Å' scene=''>		<StructureSection load='4b0z' size='340' side='right'caption='[[4b0z]], [[Resolution\|resolution]] 1.58Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4b0z]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Cbs_356 Cbs 356]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4B0Z OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4B0Z FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4b0z]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Cbs_356 Cbs 356]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4B0Z OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4B0Z FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene>, <scene name='pdbligand=SGM:MONOTHIOGLYCEROL'>SGM</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene>, <scene name='pdbligand=SGM:MONOTHIOGLYCEROL'>SGM</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4b0z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4b0z OCA], [~~http~~://pdbe.org/4b0z PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4b0z RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4b0z PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4b0z ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4b0z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4b0z OCA], [https://pdbe.org/4b0z PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4b0z RCSB], [https://www.ebi.ac.uk/pdbsum/4b0z PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4b0z ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/RPN12_SCHPO RPN12_SCHPO]] Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.	+	[[https://www.uniprot.org/uniprot/RPN12_SCHPO RPN12_SCHPO]] Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 20:		Line 20:

	==See Also==		==See Also==
-	*[[Proteasome\|Proteasome]]	+	*[[Proteasome 3D structures\|Proteasome 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 26:		Line 26:
	</StructureSection>		</StructureSection>
	[[Category: Cbs 356]]		[[Category: Cbs 356]]
		+	[[Category: Large Structures]]
	[[Category: Boehringer, J]]		[[Category: Boehringer, J]]
	[[Category: Endicott, J A]]		[[Category: Endicott, J A]]

OCA at 09:30, 6 March 2019

OCA — Wed, 06 Mar 2019 09:30:59 GMT

←Older revision		Revision as of 09:30, 6 March 2019
Line 1:		Line 1:

	==Crystal structure of S. pombe Rpn12==		==Crystal structure of S. pombe Rpn12==
-	<StructureSection load='4b0z' size='340' side='right' caption='[[4b0z]], [[Resolution\|resolution]] 1.58Å' scene=''>	+	<StructureSection load='4b0z' size='340' side='right'caption='[[4b0z]], [[Resolution\|resolution]] 1.58Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4b0z]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Cbs_356 Cbs 356]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4B0Z OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4B0Z FirstGlance]. <br>		<table><tr><td colspan='2'>[[4b0z]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Cbs_356 Cbs 356]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4B0Z OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4B0Z FirstGlance]. <br>

OCA at 12:07, 11 August 2016

OCA — Thu, 11 Aug 2016 12:07:21 GMT

←Older revision		Revision as of 12:07, 11 August 2016
Line 1:		Line 1:
		+
	==Crystal structure of S. pombe Rpn12==		==Crystal structure of S. pombe Rpn12==
	<StructureSection load='4b0z' size='340' side='right' caption='[[4b0z]], [[Resolution\|resolution]] 1.58Å' scene=''>		<StructureSection load='4b0z' size='340' side='right' caption='[[4b0z]], [[Resolution\|resolution]] 1.58Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4b0z]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Schizosaccharomyces_pombe Schizosaccharomyces pombe~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4B0Z OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4B0Z FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4b0z]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Cbs_356 Cbs 356]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4B0Z OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4B0Z FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene>, <scene name='pdbligand=SGM:MONOTHIOGLYCEROL'>SGM</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene>, <scene name='pdbligand=SGM:MONOTHIOGLYCEROL'>SGM</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4b0z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4b0z OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4b0z RCSB], [http://www.ebi.ac.uk/pdbsum/4b0z PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4b0z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4b0z OCA], [http://pdbe.org/4b0z PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4b0z RCSB], [http://www.ebi.ac.uk/pdbsum/4b0z PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4b0z ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/RPN12_SCHPO RPN12_SCHPO]] Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 14:		Line 17:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 4b0z" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 21:		Line 25:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Schizosaccharomyces pombe~~]]	+	[[Category: Cbs 356]]
	[[Category: Boehringer, J]]		[[Category: Boehringer, J]]
	[[Category: Endicott, J A]]		[[Category: Endicott, J A]]

OCA at 14:18, 4 January 2015

OCA — Sun, 04 Jan 2015 14:18:25 GMT

←Older revision		Revision as of 14:18, 4 January 2015
Line 1:		Line 1:
-	[[~~Image:~~4b0z.~~png~~\|~~left\|200px~~]]	+	==Crystal structure of S. pombe Rpn12==
		+	<StructureSection load='4b0z' size='340' side='right' caption='[[4b0z]], [[Resolution\|resolution]] 1.58Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[4b0z]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Schizosaccharomyces_pombe Schizosaccharomyces pombe]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4B0Z OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4B0Z FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene>, <scene name='pdbligand=SGM:MONOTHIOGLYCEROL'>SGM</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4b0z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4b0z OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4b0z RCSB], [http://www.ebi.ac.uk/pdbsum/4b0z PDBsum]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The ubiquitin proteasome system targets selected proteins for degradation by the 26S proteasome. Rpn12 is an essential component of the 19S regulatory particle and plays a role in recruiting the extrinsic ubiquitin receptor Rpn10. We report the crystal structure of Rpn12, a proteasomal PCI- domain containing protein. The structure helps to define a core structural motif for the PCI-domain and identifies potential sites through which Rpn12 might form protein-protein interactions. We demonstrate that mutating residues at one of these sites impairs Rpn12 binding to Rpn10 in vitro and reduces Rpn10 incorporation into proteasomes in vivo.

-	~~{{STRUCTURE_4b0z\| PDB=4b0z \| SCENE= }}~~	+	Structural and functional characterisation of Rpn12 identifies residues required for Rpn10 proteasome incorporation.,Boehringer J, Riedinger C, Paraskevopoulos K, Johnson EO, Lowe ED, Khoudian C, Smith D, Noble ME, Gordon C, Endicott JA Biochem J. 2012 Aug 20. PMID:22906049<ref>PMID:22906049</ref>

-	~~===Crystal structure~~ of S. ~~pombe Rpn12===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>

-	~~{{ABSTRACT_PUBMED_22906049}}~~	+	==See Also==
-		+	*[[Proteasome\|Proteasome]]
-	==~~About this Structure~~==	+	== References ==
-	[[~~4b0z~~]] ~~is a 2 chain structure with sequence from [http:~~//~~en.wikipedia.org/wiki/Schizosaccharomyces_pombe Schizosaccharomyces pombe]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4B0Z OCA].~~	+	<references/>
		+	__TOC__
		+	</StructureSection>
	[[Category: Schizosaccharomyces pombe]]		[[Category: Schizosaccharomyces pombe]]
-	[[Category: Boehringer, J.]]	+	[[Category: Boehringer, J]]
-	[[Category: Endicott, J A.]]	+	[[Category: Endicott, J A]]
-	[[Category: Gordon, C.]]	+	[[Category: Gordon, C]]
-	[[Category: Johnson, E O.D.]]	+	[[Category: Johnson, E O.D]]
-	[[Category: Khoudian, C.]]	+	[[Category: Khoudian, C]]
-	[[Category: Lowe, E D.]]	+	[[Category: Lowe, E D]]
-	[[Category: Noble, M E.M.]]	+	[[Category: Noble, M E.M]]
-	[[Category: Paraskevopoulos, K.]]	+	[[Category: Paraskevopoulos, K]]
-	[[Category: Riedinger, C.]]	+	[[Category: Riedinger, C]]
-	[[Category: Smith, D.]]	+	[[Category: Smith, D]]
	[[Category: Proteasome ubitquitin]]		[[Category: Proteasome ubitquitin]]
	[[Category: Protein binding]]		[[Category: Protein binding]]

OCA at 10:28, 14 November 2012

OCA — Wed, 14 Nov 2012 10:28:07 GMT

←Older revision		Revision as of 10:28, 14 November 2012
Line 5:		Line 5:
	===Crystal structure of S. pombe Rpn12===		===Crystal structure of S. pombe Rpn12===

		+	{{ABSTRACT_PUBMED_22906049}}

	==About this Structure==		==About this Structure==

OCA at 14:11, 8 November 2012

OCA — Thu, 08 Nov 2012 14:11:43 GMT

←Older revision		Revision as of 14:11, 8 November 2012
Line 1:		Line 1:
-	[[Image:4b0z.~~jpg~~\|left\|200px]]	+	[[Image:4b0z.png\|left\|200px]]

	{{STRUCTURE_4b0z\| PDB=4b0z \| SCENE= }}		{{STRUCTURE_4b0z\| PDB=4b0z \| SCENE= }}
Line 5:		Line 5:
	===Crystal structure of S. pombe Rpn12===		===Crystal structure of S. pombe Rpn12===

-	{{ABSTRACT_PUBMED_22906049}}

	==About this Structure==		==About this Structure==

OCA at 05:10, 12 September 2012

OCA — Wed, 12 Sep 2012 05:10:33 GMT

←Older revision		Revision as of 05:10, 12 September 2012
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	[[Image:4b0z.jpg\|left\|200px]]

-	~~The entry~~ 4b0z ~~is ON HOLD~~	+	{{STRUCTURE_4b0z\| PDB=4b0z \| SCENE= }}

-	~~Authors: Boehringer, J., Riedinger, C., Paraskevopoulos, K., Johnson, E.O.D., Lowe, E.D., Khoudian, C., Smith, D., Noble, M.E.M., Gordon, C., Endicott, J.A~~.	+	===Crystal structure of S. pombe Rpn12===

-	~~Description: Crystal~~ structure ~~of S~~. pombe ~~Rpn12~~	+	{{ABSTRACT_PUBMED_22906049}}
		+
		+	==About this Structure==
		+	[[4b0z]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Schizosaccharomyces_pombe Schizosaccharomyces pombe]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4B0Z OCA].
		+	[[Category: Schizosaccharomyces pombe]]
		+	[[Category: Boehringer, J.]]
		+	[[Category: Endicott, J A.]]
		+	[[Category: Gordon, C.]]
		+	[[Category: Johnson, E O.D.]]
		+	[[Category: Khoudian, C.]]
		+	[[Category: Lowe, E D.]]
		+	[[Category: Noble, M E.M.]]
		+	[[Category: Paraskevopoulos, K.]]
		+	[[Category: Riedinger, C.]]
		+	[[Category: Smith, D.]]
		+	[[Category: Proteasome ubitquitin]]
		+	[[Category: Protein binding]]

OCA: Protected "4b0z" [edit=sysop:move=sysop]

OCA — Wed, 18 Jul 2012 04:54:22 GMT

Protected "4b0z" [edit=sysop:move=sysop]

←Older revision

Revision as of 04:54, 18 July 2012

OCA: New page: '''Unreleased structure''' The entry 4b0z is ON HOLD Authors: Boehringer, J., Riedinger, C., Paraskevopoulos, K., Johnson, E.O.D., Lowe, E.D., Khoudian, C., Smith, D., Noble, M.E.M., Go...

OCA — Wed, 18 Jul 2012 04:54:21 GMT

New page: '''Unreleased structure''' The entry 4b0z is ON HOLD Authors: Boehringer, J., Riedinger, C., Paraskevopoulos, K., Johnson, E.O.D., Lowe, E.D., Khoudian, C., Smith, D., Noble, M.E.M., Go...

New page

'''Unreleased structure'''

The entry 4b0z is ON HOLD

Authors: Boehringer, J., Riedinger, C., Paraskevopoulos, K., Johnson, E.O.D., Lowe, E.D., Khoudian, C., Smith, D., Noble, M.E.M., Gordon, C., Endicott, J.A.

Description: Crystal structure of S. pombe Rpn12