4b6v - Revision history

OCA at 10:08, 14 June 2023

OCA — Wed, 14 Jun 2023 10:08:07 GMT

←Older revision		Revision as of 10:08, 14 June 2023
Line 1:		Line 1:

	==The third member of the eIF4E family represses gene expression via a novel mode of recognition of the methyl-7 guanosine cap moiety==		==The third member of the eIF4E family represses gene expression via a novel mode of recognition of the methyl-7 guanosine cap moiety==
-	<StructureSection load='4b6v' size='340' side='right'caption='[[4b6v~~]], [[NMR_Ensembles_of_Models \| 10 NMR models~~]]' scene=''>	+	<StructureSection load='4b6v' size='340' side='right'caption='[[4b6v]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4b6v]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Lk3_transgenic_mice Lk3 transgenic mice~~]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4B6V OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4B6V FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4b6v]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4B6V OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4B6V FirstGlance]. <br>
-	</td></tr>~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[4b6u\|4b6u]]</div></td></tr>~~	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4b6v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4b6v OCA], [https://pdbe.org/4b6v PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4b6v RCSB], [https://www.ebi.ac.uk/pdbsum/4b6v PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4b6v ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4b6v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4b6v OCA], [https://pdbe.org/4b6v PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4b6v RCSB], [https://www.ebi.ac.uk/pdbsum/4b6v PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4b6v ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/IF4E3_MOUSE IF4E3_MOUSE]] Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis. May act as an inhibitor of EIF4E1 activity.<ref>PMID:15153109</ref>	+	[https://www.uniprot.org/uniprot/IF4E3_MOUSE IF4E3_MOUSE] Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis. May act as an inhibitor of EIF4E1 activity.<ref>PMID:15153109</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 26:		Line 25:
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Lk3 transgenic mice~~]]	+	[[Category: Mus musculus]]
-	[[Category: Baguet, A]]	+	[[Category: Baguet A]]
-	[[Category: Borden~~, K L.B~~]]	+	[[Category: Borden KLB]]
-	[[Category: Culjkovic-Kraljcic, B]]	+	[[Category: Culjkovic-Kraljcic B]]
-	[[Category: Kornblatt~~, J A~~]]	+	[[Category: Kornblatt JA]]
-	[[Category: Osborne~~, M J~~]]	+	[[Category: Osborne MJ]]
-	[[Category: Volpon, L]]	+	[[Category: Volpon L]]
-	~~[[Category: M7g cap]]~~	+
-	~~[[Category: Translation~~]]	+

OCA at 07:01, 31 August 2022

OCA — Wed, 31 Aug 2022 07:01:44 GMT

←Older revision		Revision as of 07:01, 31 August 2022
Line 3:		Line 3:
	<StructureSection load='4b6v' size='340' side='right'caption='[[4b6v]], [[NMR_Ensembles_of_Models \| 10 NMR models]]' scene=''>		<StructureSection load='4b6v' size='340' side='right'caption='[[4b6v]], [[NMR_Ensembles_of_Models \| 10 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4b6v]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4B6V OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4B6V FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4b6v]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4B6V OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4B6V FirstGlance]. <br>
-	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4b6u\|4b6u]]</td></tr>	+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[4b6u\|4b6u]]</div></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4b6v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4b6v OCA], [~~http~~://pdbe.org/4b6v PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4b6v RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4b6v PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4b6v ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4b6v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4b6v OCA], [https://pdbe.org/4b6v PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4b6v RCSB], [https://www.ebi.ac.uk/pdbsum/4b6v PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4b6v ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/IF4E3_MOUSE IF4E3_MOUSE]] Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis. May act as an inhibitor of EIF4E1 activity.<ref>PMID:15153109</ref>	+	[[https://www.uniprot.org/uniprot/IF4E3_MOUSE IF4E3_MOUSE]] Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis. May act as an inhibitor of EIF4E1 activity.<ref>PMID:15153109</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 20:		Line 20:

	==See Also==		==See Also==
-	*[[Eukaryotic initiation factor\|Eukaryotic initiation factor]]	+	*[[Eukaryotic initiation factor 3D structures\|Eukaryotic initiation factor 3D structures]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 13:06, 13 March 2019

OCA — Wed, 13 Mar 2019 13:06:06 GMT

←Older revision		Revision as of 13:06, 13 March 2019
Line 1:		Line 1:

	==The third member of the eIF4E family represses gene expression via a novel mode of recognition of the methyl-7 guanosine cap moiety==		==The third member of the eIF4E family represses gene expression via a novel mode of recognition of the methyl-7 guanosine cap moiety==
-	<StructureSection load='4b6v' size='340' side='right' caption='[[4b6v]], [[NMR_Ensembles_of_Models \| 10 NMR models]]' scene=''>	+	<StructureSection load='4b6v' size='340' side='right'caption='[[4b6v]], [[NMR_Ensembles_of_Models \| 10 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4b6v]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4B6V OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4B6V FirstGlance]. <br>		<table><tr><td colspan='2'>[[4b6v]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4B6V OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4B6V FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4b6u\|4b6u]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4b6u\|4b6u]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4b6v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4b6v OCA], [http://pdbe.org/4b6v PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4b6v RCSB], [http://www.ebi.ac.uk/pdbsum/4b6v PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4b6v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4b6v OCA], [http://pdbe.org/4b6v PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4b6v RCSB], [http://www.ebi.ac.uk/pdbsum/4b6v PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4b6v ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 25:		Line 25:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Lk3 transgenic mice]]		[[Category: Lk3 transgenic mice]]
	[[Category: Baguet, A]]		[[Category: Baguet, A]]

OCA at 17:56, 10 May 2016

OCA — Tue, 10 May 2016 17:56:19 GMT

←Older revision		Revision as of 17:56, 10 May 2016
Line 1:		Line 1:
		+
	==The third member of the eIF4E family represses gene expression via a novel mode of recognition of the methyl-7 guanosine cap moiety==		==The third member of the eIF4E family represses gene expression via a novel mode of recognition of the methyl-7 guanosine cap moiety==
	<StructureSection load='4b6v' size='340' side='right' caption='[[4b6v]], [[NMR_Ensembles_of_Models \| 10 NMR models]]' scene=''>		<StructureSection load='4b6v' size='340' side='right' caption='[[4b6v]], [[NMR_Ensembles_of_Models \| 10 NMR models]]' scene=''>
Line 4:		Line 5:
	<table><tr><td colspan='2'>[[4b6v]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4B6V OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4B6V FirstGlance]. <br>		<table><tr><td colspan='2'>[[4b6v]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4B6V OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4B6V FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4b6u\|4b6u]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4b6u\|4b6u]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4b6v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4b6v OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4b6v RCSB], [http://www.ebi.ac.uk/pdbsum/4b6v PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4b6v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4b6v OCA], [http://pdbe.org/4b6v PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4b6v RCSB], [http://www.ebi.ac.uk/pdbsum/4b6v PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 16:		Line 17:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 4b6v" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Eukaryotic initiation factor\|Eukaryotic initiation factor]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 21:36, 24 December 2014

OCA — Wed, 24 Dec 2014 21:36:10 GMT

←Older revision		Revision as of 21:36, 24 December 2014
Line 6:		Line 6:
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4b6v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4b6v OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4b6v RCSB], [http://www.ebi.ac.uk/pdbsum/4b6v PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4b6v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4b6v OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4b6v RCSB], [http://www.ebi.ac.uk/pdbsum/4b6v PDBsum]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/IF4E3_MOUSE IF4E3_MOUSE]] Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis. May act as an inhibitor of EIF4E1 activity.<ref>PMID:15153109</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==

OCA at 16:37, 9 December 2014

OCA — Tue, 09 Dec 2014 16:37:21 GMT

←Older revision		Revision as of 16:37, 9 December 2014
Line 1:		Line 1:
-	[[~~Image:~~4b6v.~~jpg~~\|~~left~~\|~~200px~~]]	+	==The third member of the eIF4E family represses gene expression via a novel mode of recognition of the methyl-7 guanosine cap moiety==
		+	<StructureSection load='4b6v' size='340' side='right' caption='[[4b6v]], [[NMR_Ensembles_of_Models \| 10 NMR models]]' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[4b6v]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4B6V OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4B6V FirstGlance]. <br>
		+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4b6u\|4b6u]]</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4b6v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4b6v OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4b6v RCSB], [http://www.ebi.ac.uk/pdbsum/4b6v PDBsum]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Recognition of the methyl-7-guanosine (mG) cap structure on mRNA is an essential feature of mRNA metabolism and thus gene expression. Eukaryotic translation initiation factor 4E (eIF4E) promotes translation, mRNA export, proliferation, and oncogenic transformation dependent on this cap-binding activity. eIF4E-cap recognition is mediated via complementary charge interactions of the positively charged mG cap between the negative pi-electron clouds from two aromatic residues. Here, we demonstrate that a variant subfamily, eIF4E3, specifically binds the mG cap in the absence of an aromatic sandwich, using instead a different spatial arrangement of residues to provide the necessary electrostatic and van der Waals contacts. Contacts are much more extensive between eIF4E3-cap than other family members. Structural analyses of other cap-binding proteins indicate this recognition mode is atypical. We demonstrate that eIF4E3 relies on this cap-binding activity to act as a tumor suppressor, competing with the growth-promoting functions of eIF4E. In fact, reduced eIF4E3 in high eIF4E cancers suggests that eIF4E3 underlies a clinically relevant inhibitory mechanism that is lost in some malignancies. Taken together, there is more structural plasticity in cap recognition than previously thought, and this is physiologically relevant.

-	~~{{STRUCTURE_4b6v\| PDB=4b6v \| SCENE= }}~~	+	eIF4E3 acts as a tumor suppressor by utilizing an atypical mode of methyl-7-guanosine cap recognition.,Osborne MJ, Volpon L, Kornblatt JA, Culjkovic-Kraljacic B, Baguet A, Borden KL Proc Natl Acad Sci U S A. 2013 Mar 5;110(10):3877-82. doi:, 10.1073/pnas.1216862110. Epub 2013 Feb 19. PMID:23431134<ref>PMID:23431134</ref>

-	~~===The third member~~ of the ~~eIF4E family represses gene expression via a novel mode~~ of ~~recognition of the methyl-7 guanosine cap moiety===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-		+	== References ==
-	==~~About this Structure~~==	+	<references/>
-	~~[[4b6v]] is a 1 chain structure with sequence from [http:~~//~~en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4B6V OCA].~~	+	__TOC__
-	[[Category: ~~Mus musculus~~]]	+	</StructureSection>
-	[[Category: Baguet, A.]]	+	[[Category: Lk3 transgenic mice]]
-	[[Category: Borden, K L.B.]]	+	[[Category: Baguet, A]]
-	[[Category: Culjkovic-Kraljcic, B.]]	+	[[Category: Borden, K L.B]]
-	[[Category: Kornblatt, J A.]]	+	[[Category: Culjkovic-Kraljcic, B]]
-	[[Category: Osborne, M J.]]	+	[[Category: Kornblatt, J A]]
-	[[Category: Volpon, L.]]	+	[[Category: Osborne, M J]]
		+	[[Category: Volpon, L]]
	[[Category: M7g cap]]		[[Category: M7g cap]]
	[[Category: Translation]]		[[Category: Translation]]

OCA at 14:53, 27 February 2013

OCA — Wed, 27 Feb 2013 14:53:44 GMT

←Older revision		Revision as of 14:53, 27 February 2013
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	[[Image:4b6v.jpg\|left\|200px]]

-	~~The entry~~ 4b6v ~~is ON HOLD~~	+	{{STRUCTURE_4b6v\| PDB=4b6v \| SCENE= }}

-	~~Authors: Osborne, M.J., Volpon, L., Kornblatt, J.A., Culjkovic~~-~~Kraljcic, B., Baguet, A., Borden, K.L.B.~~	+	===The third member of the eIF4E family represses gene expression via a novel mode of recognition of the methyl-7 guanosine cap moiety===

-	~~Description: The third member of the eIF4E family represses gene expression via~~ a ~~novel mode of recognition of the methyl~~-~~7 guanosine~~ cap ~~moiety~~	+
		+	==About this Structure==
		+	[[4b6v]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4B6V OCA].
		+	[[Category: Mus musculus]]
		+	[[Category: Baguet, A.]]
		+	[[Category: Borden, K L.B.]]
		+	[[Category: Culjkovic-Kraljcic, B.]]
		+	[[Category: Kornblatt, J A.]]
		+	[[Category: Osborne, M J.]]
		+	[[Category: Volpon, L.]]
		+	[[Category: M7g cap]]
		+	[[Category: Translation]]

OCA: Protected "4b6v" [edit=sysop:move=sysop]

OCA — Wed, 22 Aug 2012 05:22:32 GMT

Protected "4b6v" [edit=sysop:move=sysop]

←Older revision

Revision as of 05:22, 22 August 2012

OCA: New page: '''Unreleased structure''' The entry 4b6v is ON HOLD Authors: Osborne, M.J., Volpon, L., Kornblatt, J.A., Culjkovic-Kraljcic, B., Baguet, A., Borden, K.L.B. Description: The third memb...

OCA — Wed, 22 Aug 2012 05:22:31 GMT

New page: '''Unreleased structure''' The entry 4b6v is ON HOLD Authors: Osborne, M.J., Volpon, L., Kornblatt, J.A., Culjkovic-Kraljcic, B., Baguet, A., Borden, K.L.B. Description: The third memb...

New page

'''Unreleased structure'''

The entry 4b6v is ON HOLD

Authors: Osborne, M.J., Volpon, L., Kornblatt, J.A., Culjkovic-Kraljcic, B., Baguet, A., Borden, K.L.B.

Description: The third member of the eIF4E family represses gene expression via a novel mode of recognition of the methyl-7 guanosine cap moiety