4b6x - Revision history

OCA at 10:57, 9 May 2024

OCA — Thu, 09 May 2024 10:57:39 GMT

←Older revision		Revision as of 10:57, 9 May 2024
Line 3:		Line 3:
	<StructureSection load='4b6x' size='340' side='right'caption='[[4b6x]], [[Resolution\|resolution]] 2.20Å' scene=''>		<StructureSection load='4b6x' size='340' side='right'caption='[[4b6x]], [[Resolution\|resolution]] 2.20Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4b6x]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Psesj Psesj~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4B6X OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4B6X FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4b6x]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_syringae_pv._pisi Pseudomonas syringae pv. pisi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4B6X OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4B6X FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.2Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4b6x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4b6x OCA], [https://pdbe.org/4b6x PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4b6x RCSB], [https://www.ebi.ac.uk/pdbsum/4b6x PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4b6x ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4b6x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4b6x OCA], [https://pdbe.org/4b6x PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4b6x RCSB], [https://www.ebi.ac.uk/pdbsum/4b6x PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4b6x ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/Q52432_PSESX Q52432_PSESX]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 24:		Line 27:
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Psesj~~]]	+	[[Category: Pseudomonas syringae pv. pisi]]
-	[[Category: Banfield~~, M J~~]]	+	[[Category: Banfield MJ]]
-	[[Category: Hughes~~, R K~~]]	+	[[Category: Hughes RK]]
-	[[Category: Jones~~, J D.G~~]]	+	[[Category: Jones JDG]]
-	[[Category: Piquerez~~, S J~~]]	+	[[Category: Piquerez SJ]]
-	[[Category: Sohn~~, K H]]~~	+	[[Category: Sohn KH]]
-	~~[[Category: Toxin]]~~	+
-	~~[[Category: Type 3 secreted effector~~]]	+

OCA at 07:01, 31 August 2022

OCA — Wed, 31 Aug 2022 07:01:48 GMT

←Older revision		Revision as of 07:01, 31 August 2022
Line 3:		Line 3:
	<StructureSection load='4b6x' size='340' side='right'caption='[[4b6x]], [[Resolution\|resolution]] 2.20Å' scene=''>		<StructureSection load='4b6x' size='340' side='right'caption='[[4b6x]], [[Resolution\|resolution]] 2.20Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4b6x]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Psesj Psesj]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4B6X OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4B6X FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4b6x]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Psesj Psesj]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4B6X OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4B6X FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4b6x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4b6x OCA], [~~http~~://pdbe.org/4b6x PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4b6x RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4b6x PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4b6x ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4b6x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4b6x OCA], [https://pdbe.org/4b6x PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4b6x RCSB], [https://www.ebi.ac.uk/pdbsum/4b6x PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4b6x ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 18:		Line 18:

	==See Also==		==See Also==
-	*[[Avirulence protein\|Avirulence protein]]	+	*[[Avirulence protein 3D structures\|Avirulence protein 3D structures]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 13:53, 13 March 2019

OCA — Wed, 13 Mar 2019 13:53:50 GMT

←Older revision		Revision as of 13:53, 13 March 2019
Line 1:		Line 1:

	==Crystal structure of in planta processed AvrRps4==		==Crystal structure of in planta processed AvrRps4==
-	<StructureSection load='4b6x' size='340' side='right' caption='[[4b6x]], [[Resolution\|resolution]] 2.20Å' scene=''>	+	<StructureSection load='4b6x' size='340' side='right'caption='[[4b6x]], [[Resolution\|resolution]] 2.20Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4b6x]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Psesj Psesj]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4B6X OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4B6X FirstGlance]. <br>		<table><tr><td colspan='2'>[[4b6x]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Psesj Psesj]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4B6X OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4B6X FirstGlance]. <br>
Line 23:		Line 23:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Psesj]]		[[Category: Psesj]]
	[[Category: Banfield, M J]]		[[Category: Banfield, M J]]

OCA at 14:52, 11 August 2016

OCA — Thu, 11 Aug 2016 14:52:54 GMT

←Older revision		Revision as of 14:52, 11 August 2016
Line 1:		Line 1:
		+
	==Crystal structure of in planta processed AvrRps4==		==Crystal structure of in planta processed AvrRps4==
	<StructureSection load='4b6x' size='340' side='right' caption='[[4b6x]], [[Resolution\|resolution]] 2.20Å' scene=''>		<StructureSection load='4b6x' size='340' side='right' caption='[[4b6x]], [[Resolution\|resolution]] 2.20Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4b6x]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Pseudomonas_syringae_pv._pisi Pseudomonas syringae pv. pisi~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4B6X OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4B6X FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4b6x]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Psesj Psesj]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4B6X OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4B6X FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4b6x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4b6x OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4b6x RCSB], [http://www.ebi.ac.uk/pdbsum/4b6x PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4b6x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4b6x OCA], [http://pdbe.org/4b6x PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4b6x RCSB], [http://www.ebi.ac.uk/pdbsum/4b6x PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4b6x ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 14:		Line 15:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 4b6x" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 21:		Line 23:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Pseudomonas syringae pv. pisi~~]]	+	[[Category: Psesj]]
	[[Category: Banfield, M J]]		[[Category: Banfield, M J]]
	[[Category: Hughes, R K]]		[[Category: Hughes, R K]]

OCA at 13:19, 4 January 2015

OCA — Sun, 04 Jan 2015 13:19:31 GMT

←Older revision		Revision as of 13:19, 4 January 2015
Line 1:		Line 1:
-	[[~~Image:~~4b6x.~~png~~\|~~left\|200px~~]]	+	==Crystal structure of in planta processed AvrRps4==
		+	<StructureSection load='4b6x' size='340' side='right' caption='[[4b6x]], [[Resolution\|resolution]] 2.20Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[4b6x]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseudomonas_syringae_pv._pisi Pseudomonas syringae pv. pisi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4B6X OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4B6X FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4b6x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4b6x OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4b6x RCSB], [http://www.ebi.ac.uk/pdbsum/4b6x PDBsum]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Gram-negative phytopathogenic bacteria translocate effector proteins into plant cells to subvert host defenses. These effectors can be recognized by plant nucleotide-binding-leucine-rich repeat immune receptors, triggering defense responses that restrict pathogen growth. AvrRps4, an effector protein from Pseudomonas syringae pv. pisi, triggers RPS4-dependent immunity in resistant accessions of Arabidopsis. To better understand the molecular basis of AvrRps4-triggered immunity, we determined the crystal structure of processed AvrRps4 (AvrRps4(C), residues 134-221), revealing that it forms an antiparallel alpha-helical coiled coil. Structure-informed mutagenesis reveals an electronegative surface patch in AvrRps4(C) required for recognition by RPS4; mutations in this region can also uncouple triggering of the hypersensitive response from disease resistance. This uncoupling may result from a lower level of defense activation, sufficient for avirulence but not for triggering a hypersensitive response. Natural variation in AvrRps4 reveals distinct recognition specificities that involve a surface-exposed residue. Recently, a direct interaction between AvrRps4 and Enhanced Disease Susceptibility 1 has been implicated in activation of immunity. However, we were unable to detect direct interaction between AvrRps4 and Enhanced Disease Susceptibility 1 after coexpression in Nicotiana benthamiana or in yeast cells. How intracellular plant immune receptors activate defense upon effector perception remains an unsolved problem. The structure of AvrRps4(C), and identification of functionally important residues for its activation of plant immunity, advances our understanding of these processes in a well-defined model pathosystem.

-	~~{{STRUCTURE_4b6x\| PDB=4b6x \| SCENE= }}~~	+	Distinct regions of the Pseudomonas syringae coiled-coil effector AvrRps4 are required for activation of immunity.,Sohn KH, Hughes RK, Piquerez SJ, Jones JD, Banfield MJ Proc Natl Acad Sci U S A. 2012 Sep 17. PMID:22988101<ref>PMID:22988101</ref>

-	~~===Crystal structure~~ of ~~in planta processed AvrRps4===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>

-	~~{{ABSTRACT_PUBMED_22988101}}~~	+	==See Also==
-		+	*[[Avirulence protein\|Avirulence protein]]
-	==~~About this Structure~~==	+	== References ==
-	[[~~4b6x~~]] ~~is a 2 chain structure with sequence from [http:~~//~~en.wikipedia.org/wiki/Pseudomonas_syringae_pv._pisi Pseudomonas syringae pv. pisi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4B6X OCA].~~	+	<references/>
		+	__TOC__
		+	</StructureSection>
	[[Category: Pseudomonas syringae pv. pisi]]		[[Category: Pseudomonas syringae pv. pisi]]
-	[[Category: Banfield, M J.]]	+	[[Category: Banfield, M J]]
-	[[Category: Hughes, R K.]]	+	[[Category: Hughes, R K]]
-	[[Category: Jones, J D.G.]]	+	[[Category: Jones, J D.G]]
-	[[Category: Piquerez, S J.]]	+	[[Category: Piquerez, S J]]
-	[[Category: Sohn, K H.]]	+	[[Category: Sohn, K H]]
	[[Category: Toxin]]		[[Category: Toxin]]
	[[Category: Type 3 secreted effector]]		[[Category: Type 3 secreted effector]]

OCA at 20:34, 26 September 2012

OCA — Wed, 26 Sep 2012 20:34:06 GMT

←Older revision		Revision as of 20:34, 26 September 2012
Line 1:		Line 1:
-	[[Image:4b6x.~~jpg~~\|left\|200px]]	+	[[Image:4b6x.png\|left\|200px]]

	{{STRUCTURE_4b6x\| PDB=4b6x \| SCENE= }}		{{STRUCTURE_4b6x\| PDB=4b6x \| SCENE= }}
Line 5:		Line 5:
	===Crystal structure of in planta processed AvrRps4===		===Crystal structure of in planta processed AvrRps4===

		+	{{ABSTRACT_PUBMED_22988101}}

	==About this Structure==		==About this Structure==
Line 13:		Line 14:
	[[Category: Jones, J D.G.]]		[[Category: Jones, J D.G.]]
	[[Category: Piquerez, S J.]]		[[Category: Piquerez, S J.]]
-	[[Category: Sohn, K.]]	+	[[Category: Sohn, K H.]]
	[[Category: Toxin]]		[[Category: Toxin]]
	[[Category: Type 3 secreted effector]]		[[Category: Type 3 secreted effector]]

OCA at 07:20, 19 September 2012

OCA — Wed, 19 Sep 2012 07:20:40 GMT

←Older revision		Revision as of 07:20, 19 September 2012
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	[[Image:4b6x.jpg\|left\|200px]]

-	~~The entry~~ 4b6x ~~is ON HOLD~~ ~~until Paper Publication~~	+	{{STRUCTURE_4b6x\| PDB=4b6x \| SCENE= }}

-	~~Authors: Sohn, K., Hughes, R.K., Piquerez, S.J., Jones, J.D.G., Banfield, M.J.~~	+	===Crystal structure of in planta processed AvrRps4===

-	~~Description: Crystal~~ structure ~~of in planta processed AvrRps4~~	+
		+	==About this Structure==
		+	[[4b6x]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseudomonas_syringae_pv._pisi Pseudomonas syringae pv. pisi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4B6X OCA].
		+	[[Category: Pseudomonas syringae pv. pisi]]
		+	[[Category: Banfield, M J.]]
		+	[[Category: Hughes, R K.]]
		+	[[Category: Jones, J D.G.]]
		+	[[Category: Piquerez, S J.]]
		+	[[Category: Sohn, K.]]
		+	[[Category: Toxin]]
		+	[[Category: Type 3 secreted effector]]

OCA at 04:35, 29 August 2012

OCA — Wed, 29 Aug 2012 04:35:46 GMT

←Older revision		Revision as of 04:35, 29 August 2012
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 4b6x is ON HOLD	+	The entry 4b6x is ON HOLD until Paper Publication

	Authors: Sohn, K., Hughes, R.K., Piquerez, S.J., Jones, J.D.G., Banfield, M.J.		Authors: Sohn, K., Hughes, R.K., Piquerez, S.J., Jones, J.D.G., Banfield, M.J.

	Description: Crystal structure of in planta processed AvrRps4		Description: Crystal structure of in planta processed AvrRps4

OCA: Protected "4b6x" [edit=sysop:move=sysop]

OCA — Wed, 22 Aug 2012 05:22:34 GMT

Protected "4b6x" [edit=sysop:move=sysop]

←Older revision

Revision as of 05:22, 22 August 2012

OCA: New page: '''Unreleased structure''' The entry 4b6x is ON HOLD Authors: Sohn, K., Hughes, R.K., Piquerez, S.J., Jones, J.D.G., Banfield, M.J. Description: Crystal structure of in planta processe...

OCA — Wed, 22 Aug 2012 05:22:33 GMT

New page: '''Unreleased structure''' The entry 4b6x is ON HOLD Authors: Sohn, K., Hughes, R.K., Piquerez, S.J., Jones, J.D.G., Banfield, M.J. Description: Crystal structure of in planta processe...

New page

'''Unreleased structure'''

The entry 4b6x is ON HOLD

Authors: Sohn, K., Hughes, R.K., Piquerez, S.J., Jones, J.D.G., Banfield, M.J.

Description: Crystal structure of in planta processed AvrRps4