4be9 - Revision history

OCA at 11:49, 20 December 2023

OCA — Wed, 20 Dec 2023 11:49:13 GMT

←Older revision		Revision as of 11:49, 20 December 2023
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	<StructureSection load='4be9' size='340' side='right'caption='[[4be9]], [[Resolution\|resolution]] 2.00Å' scene=''>		<StructureSection load='4be9' size='340' side='right'caption='[[4be9]], [[Resolution\|resolution]] 2.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4be9]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BE9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4BE9 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4be9]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Ophiostoma_piceae Ophiostoma piceae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BE9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4BE9 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1PE:PENTAETHYLENE+GLYCOL'>1PE</scene>, <scene name='pdbligand=7P9:[(2R)-2-HEPTANOYLOXY-3-PHOSPHONOOXY-PROPYL]+NONANOATE'>7P9</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene~~></td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2Å</td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[4be4\|4be4]]</div></td></tr>~~	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1PE:PENTAETHYLENE+GLYCOL'>1PE</scene>, <scene name='pdbligand=7P9:[(2R)-2-HEPTANOYLOXY-3-PHOSPHONOOXY-PROPYL]+NONANOATE'>7P9</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene></td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Sterol_esterase Sterol esterase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.1.13 3.1.1.13] </span></td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4be9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4be9 OCA], [https://pdbe.org/4be9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4be9 RCSB], [https://www.ebi.ac.uk/pdbsum/4be9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4be9 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4be9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4be9 OCA], [https://pdbe.org/4be9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4be9 RCSB], [https://www.ebi.ac.uk/pdbsum/4be9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4be9 ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/Q2TFW1_9PEZI Q2TFW1_9PEZI]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 26:		Line 27:
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Sterol esterase~~]]	+	[[Category: Ophiostoma piceae]]
-	[[Category: Barriuso, J]]	+	[[Category: Barriuso J]]
-	[[Category: Gonzalez~~, M J~~]]	+	[[Category: Gonzalez MJ]]
-	[[Category: Gutierrez-Fernandez, J]]	+	[[Category: Gutierrez-Fernandez J]]
-	[[Category: Hermoso~~, J A~~]]	+	[[Category: Hermoso JA]]
-	[[Category: Prieto, A]]	+	[[Category: Prieto A]]
-	[[Category: Vaquero~~, M E]]~~	+	[[Category: Vaquero ME]]
-	~~[[Category: Hydrolase]]~~	+
-	~~[[Category: Ophiostoma~~]]	+

OCA at 07:10, 31 August 2022

OCA — Wed, 31 Aug 2022 07:10:27 GMT

←Older revision		Revision as of 07:10, 31 August 2022
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	<StructureSection load='4be9' size='340' side='right'caption='[[4be9]], [[Resolution\|resolution]] 2.00Å' scene=''>		<StructureSection load='4be9' size='340' side='right'caption='[[4be9]], [[Resolution\|resolution]] 2.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4be9]] is a 2 chain structure ~~with sequence from [http://en.wikipedia.org/wiki/Cbs_108.21 Cbs 108.21]~~. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BE9 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4BE9 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4be9]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BE9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4BE9 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=1PE:PENTAETHYLENE+GLYCOL'>1PE</scene>, <scene name='pdbligand=7P9:[(2R)-2-HEPTANOYLOXY-3-PHOSPHONOOXY-PROPYL]+NONANOATE'>7P9</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1PE:PENTAETHYLENE+GLYCOL'>1PE</scene>, <scene name='pdbligand=7P9:[(2R)-2-HEPTANOYLOXY-3-PHOSPHONOOXY-PROPYL]+NONANOATE'>7P9</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4be4\|4be4]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[4be4\|4be4]]</div></td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/Sterol_esterase Sterol esterase], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.1.13 3.1.1.13] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Sterol_esterase Sterol esterase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.1.13 3.1.1.13] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4be9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4be9 OCA], [~~http~~://pdbe.org/4be9 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4be9 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4be9 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4be9 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4be9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4be9 OCA], [https://pdbe.org/4be9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4be9 RCSB], [https://www.ebi.ac.uk/pdbsum/4be9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4be9 ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 20:		Line 20:

	==See Also==		==See Also==
-	*[[Cholesterol esterase\|Cholesterol esterase]]	+	*[[Cholesterol esterase 3D structures\|Cholesterol esterase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Cbs 108 21]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Sterol esterase]]		[[Category: Sterol esterase]]

OCA at 13:48, 13 March 2019

OCA — Wed, 13 Mar 2019 13:48:20 GMT

←Older revision		Revision as of 13:48, 13 March 2019
Line 1:		Line 1:

	==Open conformation of O. piceae sterol esterase==		==Open conformation of O. piceae sterol esterase==
-	<StructureSection load='4be9' size='340' side='right' caption='[[4be9]], [[Resolution\|resolution]] 2.00Å' scene=''>	+	<StructureSection load='4be9' size='340' side='right'caption='[[4be9]], [[Resolution\|resolution]] 2.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4be9]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Cbs_108.21 Cbs 108.21]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BE9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4BE9 FirstGlance]. <br>		<table><tr><td colspan='2'>[[4be9]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Cbs_108.21 Cbs 108.21]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BE9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4BE9 FirstGlance]. <br>
Line 18:		Line 18:
	</div>		</div>
	<div class="pdbe-citations 4be9" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 4be9" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Cholesterol esterase\|Cholesterol esterase]]
	== References ==		== References ==
	<references/>		<references/>
Line 23:		Line 26:
	</StructureSection>		</StructureSection>
	[[Category: Cbs 108 21]]		[[Category: Cbs 108 21]]
		+	[[Category: Large Structures]]
	[[Category: Sterol esterase]]		[[Category: Sterol esterase]]
	[[Category: Barriuso, J]]		[[Category: Barriuso, J]]

OCA at 09:40, 11 August 2016

OCA — Thu, 11 Aug 2016 09:40:04 GMT

←Older revision		Revision as of 09:40, 11 August 2016
Line 1:		Line 1:
		+
	==Open conformation of O. piceae sterol esterase==		==Open conformation of O. piceae sterol esterase==
	<StructureSection load='4be9' size='340' side='right' caption='[[4be9]], [[Resolution\|resolution]] 2.00Å' scene=''>		<StructureSection load='4be9' size='340' side='right' caption='[[4be9]], [[Resolution\|resolution]] 2.00Å' scene=''>
Line 6:		Line 7:
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4be4\|4be4]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4be4\|4be4]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Sterol_esterase Sterol esterase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.1.13 3.1.1.13] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Sterol_esterase Sterol esterase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.1.13 3.1.1.13] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4be9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4be9 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4be9 RCSB], [http://www.ebi.ac.uk/pdbsum/4be9 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4be9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4be9 OCA], [http://pdbe.org/4be9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4be9 RCSB], [http://www.ebi.ac.uk/pdbsum/4be9 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4be9 ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 16:		Line 17:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 4be9" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 10:47, 20 January 2015

OCA — Tue, 20 Jan 2015 10:47:50 GMT

←Older revision		Revision as of 10:47, 20 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4be9]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Cbs_108.21 Cbs 108.21]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BE9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4BE9 FirstGlance]. <br>		<table><tr><td colspan='2'>[[4be9]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Cbs_108.21 Cbs 108.21]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BE9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4BE9 FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=1PE:PENTAETHYLENE+GLYCOL'>1PE</scene>, <scene name='pdbligand=7P9:[(2R)-2-HEPTANOYLOXY-3-PHOSPHONOOXY-PROPYL]+NONANOATE'>7P9</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=1PE:PENTAETHYLENE+GLYCOL'>1PE</scene>, <scene name='pdbligand=7P9:[(2R)-2-HEPTANOYLOXY-3-PHOSPHONOOXY-PROPYL]+NONANOATE'>7P9</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4be4\|4be4]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4be4\|4be4]]</td></tr>
-	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Sterol_esterase Sterol esterase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.1.13 3.1.1.13] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Sterol_esterase Sterol esterase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.1.13 3.1.1.13] </span></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4be9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4be9 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4be9 RCSB], [http://www.ebi.ac.uk/pdbsum/4be9 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4be9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4be9 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4be9 RCSB], [http://www.ebi.ac.uk/pdbsum/4be9 PDBsum]</span></td></tr>
-	<table>	+	</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 22:		Line 22:
	[[Category: Cbs 108 21]]		[[Category: Cbs 108 21]]
	[[Category: Sterol esterase]]		[[Category: Sterol esterase]]
-	[[Category: Barriuso, J.]]	+	[[Category: Barriuso, J]]
-	[[Category: Gonzalez, M J.]]	+	[[Category: Gonzalez, M J]]
-	[[Category: Gutierrez-Fernandez, J.]]	+	[[Category: Gutierrez-Fernandez, J]]
-	[[Category: Hermoso, J A.]]	+	[[Category: Hermoso, J A]]
-	[[Category: Prieto, A.]]	+	[[Category: Prieto, A]]
-	[[Category: Vaquero, M E.]]	+	[[Category: Vaquero, M E]]
	[[Category: Hydrolase]]		[[Category: Hydrolase]]
	[[Category: Ophiostoma]]		[[Category: Ophiostoma]]

OCA at 07:00, 24 September 2014

OCA — Wed, 24 Sep 2014 07:00:13 GMT

←Older revision		Revision as of 07:00, 24 September 2014
Line 1:		Line 1:
-	~~{{STRUCTURE_4be9~~\| ~~PDB~~=4be9 \| ~~SCENE~~= }}	+	==Open conformation of O. piceae sterol esterase==
-	===~~Open conformation of O~~. ~~piceae sterol~~ esterase===	+	<StructureSection load='4be9' size='340' side='right' caption='[[4be9]], [[Resolution\|resolution]] 2.00Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[4be9]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Cbs_108.21 Cbs 108.21]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BE9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4BE9 FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=1PE:PENTAETHYLENE+GLYCOL'>1PE</scene>, <scene name='pdbligand=7P9:[(2R)-2-HEPTANOYLOXY-3-PHOSPHONOOXY-PROPYL]+NONANOATE'>7P9</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4be4\|4be4]]</td></tr>
		+	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Sterol_esterase Sterol esterase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.1.13 3.1.1.13] </span></td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4be9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4be9 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4be9 RCSB], [http://www.ebi.ac.uk/pdbsum/4be9 PDBsum]</span></td></tr>
		+	<table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Sterol esterases are able to efficiently hydrolyze both sterol esters and triglycerides and to carry out synthesis reactions in the presence of organic solvents. Their high versatility makes them excellent candidates for biotechnological purposes. Sterol esterase from fungus Ophiostoma piceae (OPE) belongs to the family abH03.01 of the Candida rugosa lipase-like proteins. Crystal structures of OPE were solved in this study for the closed and open conformations. Enzyme activation involves a large displacement of the conserved lid, structural rearrangements of loop alpha16-alpha17, and formation of a dimer with a large opening. Three PEG molecules are placed in the active site, mimicking chains of the triglyceride substrate, demonstrating the position of the oxyanion hole and the three pockets that accommodate the sn-1, sn-2 and sn-3 fatty acids chains. One of them is an internal tunnel, connecting the active center with the outer surface of the enzyme 30A far from the catalytic Ser220. Based on our structural and biochemical results we propose a mechanism by which a great variety of different substrates can be hydrolyzed in OPE paving the way for the construction of new variants to improve the catalytic properties of these enzymes and their biotechnological applications.

-	~~==About this Structure==~~	+	Crystal structures of Ophiostoma piceae sterol esterase: Structural insights into activation mechanism and product release.,Gutierrez-Fernandez J, Vaquero ME, Prieto A, Barriuso J, Martinez MJ, Hermoso JA J Struct Biol. 2014 Sep;187(3):215-22. doi: 10.1016/j.jsb.2014.07.007. Epub 2014 , Aug 7. PMID:25108239<ref>PMID:25108239</ref>
-	~~[[4be9]] is a 2 chain structure~~. ~~Full crystallographic information is available from [http~~:/~~/oca~~.~~weizmann~~.ac.il/~~oca-bin~~/~~ocashort?id~~=~~4BE9 OCA~~].	+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Cbs 108 21]]
	[[Category: Sterol esterase]]		[[Category: Sterol esterase]]
	[[Category: Barriuso, J.]]		[[Category: Barriuso, J.]]

OCA at 09:29, 26 March 2014

OCA — Wed, 26 Mar 2014 09:29:56 GMT

←Older revision		Revision as of 09:29, 26 March 2014
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	{{STRUCTURE_4be9\| PDB=4be9 \| SCENE= }}
		+	===Open conformation of O. piceae sterol esterase===

-	~~The entry~~ 4be9 is ~~ON HOLD until Paper Publication~~	+	==About this Structure==
-		+	[[4be9]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BE9 OCA].
-	~~Authors~~: ~~Gutierrez-Fernandez, J~~.~~, Vaquero, M~~.E.~~, Prieto, A~~., Barriuso, J., Gonzalez, M.J., Hermoso, J.A.	+	[[Category: Sterol esterase]]
-		+	[[Category: Barriuso, J.]]
-	~~Description~~: ~~Open conformation of O~~. ~~piceae sterol esterase~~	+	[[Category: Gonzalez, M J.]]
		+	[[Category: Gutierrez-Fernandez, J.]]
		+	[[Category: Hermoso, J A.]]
		+	[[Category: Prieto, A.]]
		+	[[Category: Vaquero, M E.]]
		+	[[Category: Hydrolase]]
		+	[[Category: Ophiostoma]]

OCA: Protected "4be9" [edit=sysop:move=sysop]

OCA — Wed, 13 Mar 2013 09:43:31 GMT

Protected "4be9" [edit=sysop:move=sysop]

←Older revision

Revision as of 09:43, 13 March 2013

OCA: New page: '''Unreleased structure''' The entry 4be9 is ON HOLD until Paper Publication Authors: Gutierrez-Fernandez, J., Vaquero, M.E., Prieto, A., Barriuso, J., Gonzalez, M.J., Hermoso, J.A. De...

OCA — Wed, 13 Mar 2013 09:43:30 GMT

New page: '''Unreleased structure''' The entry 4be9 is ON HOLD until Paper Publication Authors: Gutierrez-Fernandez, J., Vaquero, M.E., Prieto, A., Barriuso, J., Gonzalez, M.J., Hermoso, J.A. De...

New page

'''Unreleased structure'''

The entry 4be9 is ON HOLD until Paper Publication

Authors: Gutierrez-Fernandez, J., Vaquero, M.E., Prieto, A., Barriuso, J., Gonzalez, M.J., Hermoso, J.A.

Description: Open conformation of O. piceae sterol esterase