4bn0 - Revision history

OCA at 11:54, 20 December 2023

OCA — Wed, 20 Dec 2023 11:54:59 GMT

←Older revision		Revision as of 11:54, 20 December 2023
Line 3:		Line 3:
	<StructureSection load='4bn0' size='340' side='right'caption='[[4bn0]], [[Resolution\|resolution]] 2.11Å' scene=''>		<StructureSection load='4bn0' size='340' side='right'caption='[[4bn0]], [[Resolution\|resolution]] 2.11Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4bn0]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Campylobacter_pylori Campylobacter~~ pylori]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BN0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4BN0 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4bn0]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Helicobacter_pylori_26695 Helicobacter pylori 26695]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BN0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4BN0 FirstGlance]. <br>
-	</td></tr><tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat">~~<div style='overflow: auto; max~~-~~height: 3em;'>[[4bmx\|4bmx]]~~, [[~~4bmy~~\|~~4bmy~~]]~~, [[4bmz\|4bmz]]</div></td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.11Å</td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Adenosylhomocysteine_nucleosidase Adenosylhomocysteine nucleosidase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.~~2.9 3.2.2.9] </span>~~</td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4bn0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bn0 OCA], [https://pdbe.org/4bn0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4bn0 RCSB], [https://www.ebi.ac.uk/pdbsum/4bn0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4bn0 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4bn0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bn0 OCA], [https://pdbe.org/4bn0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4bn0 RCSB], [https://www.ebi.ac.uk/pdbsum/4bn0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4bn0 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/~~MTNN_HELPY MTNN_HELPY~~]~~] Responsible for cleavage~~ of the glycosidic bond in ~~both~~ 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH) (~~By similarity~~).	+	[https://www.uniprot.org/uniprot/MQMTN_HELPY MQMTN_HELPY] Catalyzes the direct conversion of aminodeoxyfutalosine (AFL) into dehypoxanthine futalosine (DHFL) and adenine via the hydrolysis of the N-glycosidic bond; this reaction seems to represent an essential step in the menaquinone biosynthesis pathway in Helicobacter species. Can also probably catalyzes the hydrolysis of 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively. These other activities highlight the tremendous versatility of the enzyme, which also plays key roles in S-adenosylmethionine recycling and in the biosynthesis of the quorum-sensing molecule autoinducer-2. Does not act on futalosine (FL) as substrate.<ref>PMID:21098241</ref> <ref>PMID:24083939</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Adenosylhomocysteine nucleosidase]]~~	+	[[Category: Helicobacter pylori 26695]]
-	~~[[Category: Campylobacter~~ pylori]]	+
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Davies~~, G J~~]]	+	[[Category: Davies GJ]]
-	[[Category: Kim~~, R Q~~]]	+	[[Category: Kim RQ]]
-	[[Category: Offen~~, W A~~]]	+	[[Category: Offen WA]]
-	[[Category: Stubbs~~, K A]]~~	+	[[Category: Stubbs KA]]
-	~~[[Category: Hydrolase~~]]	+

OCA at 07:19, 31 August 2022

OCA — Wed, 31 Aug 2022 07:19:01 GMT

←Older revision		Revision as of 07:19, 31 August 2022
Line 3:		Line 3:
	<StructureSection load='4bn0' size='340' side='right'caption='[[4bn0]], [[Resolution\|resolution]] 2.11Å' scene=''>		<StructureSection load='4bn0' size='340' side='right'caption='[[4bn0]], [[Resolution\|resolution]] 2.11Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4bn0]] is a 4 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Campylobacter_pylori Campylobacter pylori]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BN0 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4BN0 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4bn0]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Campylobacter_pylori Campylobacter pylori]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BN0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4BN0 FirstGlance]. <br>
-	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4bmx\|4bmx]], [[4bmy\|4bmy]], [[4bmz\|4bmz]]</td></tr>	+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[4bmx\|4bmx]], [[4bmy\|4bmy]], [[4bmz\|4bmz]]</div></td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/Adenosylhomocysteine_nucleosidase Adenosylhomocysteine nucleosidase], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.2.9 3.2.2.9] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Adenosylhomocysteine_nucleosidase Adenosylhomocysteine nucleosidase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.2.9 3.2.2.9] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4bn0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bn0 OCA], [~~http~~://pdbe.org/4bn0 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4bn0 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4bn0 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4bn0 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4bn0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bn0 OCA], [https://pdbe.org/4bn0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4bn0 RCSB], [https://www.ebi.ac.uk/pdbsum/4bn0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4bn0 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/MTNN_HELPY MTNN_HELPY]] Responsible for cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH) (By similarity).	+	[[https://www.uniprot.org/uniprot/MTNN_HELPY MTNN_HELPY]] Responsible for cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH) (By similarity).
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==

OCA at 13:29, 13 March 2019

OCA — Wed, 13 Mar 2019 13:29:49 GMT

←Older revision		Revision as of 13:29, 13 March 2019
Line 1:		Line 1:

	==Structure of futalosine hydrolase mutant of Helicobacter pylori strain 26695==		==Structure of futalosine hydrolase mutant of Helicobacter pylori strain 26695==
-	<StructureSection load='4bn0' size='340' side='right' caption='[[4bn0]], [[Resolution\|resolution]] 2.11Å' scene=''>	+	<StructureSection load='4bn0' size='340' side='right'caption='[[4bn0]], [[Resolution\|resolution]] 2.11Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4bn0]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Campylobacter_pylori Campylobacter pylori]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BN0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4BN0 FirstGlance]. <br>		<table><tr><td colspan='2'>[[4bn0]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Campylobacter_pylori Campylobacter pylori]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BN0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4BN0 FirstGlance]. <br>
Line 25:		Line 25:
	[[Category: Adenosylhomocysteine nucleosidase]]		[[Category: Adenosylhomocysteine nucleosidase]]
	[[Category: Campylobacter pylori]]		[[Category: Campylobacter pylori]]
		+	[[Category: Large Structures]]
	[[Category: Davies, G J]]		[[Category: Davies, G J]]
	[[Category: Kim, R Q]]		[[Category: Kim, R Q]]

OCA at 04:36, 5 August 2016

OCA — Fri, 05 Aug 2016 04:36:24 GMT

←Older revision		Revision as of 04:36, 5 August 2016
Line 1:		Line 1:
		+
	==Structure of futalosine hydrolase mutant of Helicobacter pylori strain 26695==		==Structure of futalosine hydrolase mutant of Helicobacter pylori strain 26695==
	<StructureSection load='4bn0' size='340' side='right' caption='[[4bn0]], [[Resolution\|resolution]] 2.11Å' scene=''>		<StructureSection load='4bn0' size='340' side='right' caption='[[4bn0]], [[Resolution\|resolution]] 2.11Å' scene=''>
Line 5:		Line 6:
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4bmx\|4bmx]], [[4bmy\|4bmy]], [[4bmz\|4bmz]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4bmx\|4bmx]], [[4bmy\|4bmy]], [[4bmz\|4bmz]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Adenosylhomocysteine_nucleosidase Adenosylhomocysteine nucleosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.2.9 3.2.2.9] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Adenosylhomocysteine_nucleosidase Adenosylhomocysteine nucleosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.2.9 3.2.2.9] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4bn0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bn0 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4bn0 RCSB], [http://www.ebi.ac.uk/pdbsum/4bn0 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4bn0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bn0 OCA], [http://pdbe.org/4bn0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4bn0 RCSB], [http://www.ebi.ac.uk/pdbsum/4bn0 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4bn0 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 17:		Line 18:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 4bn0" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 15:50, 25 December 2014

OCA — Thu, 25 Dec 2014 15:50:49 GMT

←Older revision		Revision as of 15:50, 25 December 2014
Line 1:		Line 1:
-	~~{{STRUCTURE_4bn0\| PDB=4bn0 \| SCENE= }}~~	+	==Structure of futalosine hydrolase mutant of Helicobacter pylori strain 26695==
-	===Structure of futalosine hydrolase mutant of Helicobacter pylori strain 26695===	+	<StructureSection load='4bn0' size='340' side='right' caption='[[4bn0]], [[Resolution\|resolution]] 2.11Å' scene=''>
-	~~{{ABSTRACT_PUBMED_24419390}}~~	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[4bn0]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Campylobacter_pylori Campylobacter pylori]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BN0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4BN0 FirstGlance]. <br>
-	==Function==	+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4bmx\|4bmx]], [[4bmy\|4bmy]], [[4bmz\|4bmz]]</td></tr>
		+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Adenosylhomocysteine_nucleosidase Adenosylhomocysteine nucleosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.2.9 3.2.2.9] </span></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4bn0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bn0 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4bn0 RCSB], [http://www.ebi.ac.uk/pdbsum/4bn0 PDBsum]</span></td></tr>
		+	</table>
		+	== Function ==
	[[http://www.uniprot.org/uniprot/MTNN_HELPY MTNN_HELPY]] Responsible for cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH) (By similarity).		[[http://www.uniprot.org/uniprot/MTNN_HELPY MTNN_HELPY]] Responsible for cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH) (By similarity).
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The recently discovered futalosine pathway is a promising target for the development of new antibiotics. The enzymes involved in this pathway are crucial for the biosynthesis of the essential prokaryotic respiratory compound menaquinone, and as the pathway is limited to few bacterial species such as the gastric pathogen Helicobacter pylori it is a potential target for specific antibiotics. In this report, the crystal structure of an H. pylori methylthioadenosine nucleosidase (MTAN; an enzyme with broad specificity and activity towards 6-amino-6-deoxyfutalosine), which is involved in the second step of menaquinone biosynthesis, has been elucidated at a resolution of 1.76 A and refined with R factors of Rwork = 17% and Rfree = 21%. Activity studies on the wild type and active-site mutants show that the hydrolysis of 6-amino-6-deoxyfutalosine follows a mechanism similar to that of Escherichia coli MTAN. Further evidence for this mode of action is supplied by the crystal structures of active-site mutants. Through the use of reaction intermediates, the structures give additional evidence for the previously proposed nucleosidase mechanism. These structures and the confirmed reaction mechanism will provide a structural basis for the design of new inhibitors targeting the futalosine pathway.

-	~~==About this Structure==~~	+	Structural enzymology of Helicobacter pylori methylthioadenosine nucleosidase in the futalosine pathway.,Kim RQ, Offen WA, Davies GJ, Stubbs KA Acta Crystallogr D Biol Crystallogr. 2014 Jan;70(Pt 1):177-85. doi:, 10.1107/S1399004713026655. Epub 2013 Dec 31. PMID:24419390<ref>PMID:24419390</ref>
-	~~[[4bn0]] is a 4 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Campylobacter_pylori Campylobacter pylori]~~. ~~Full crystallographic information is available from [http~~:/~~/oca~~.~~weizmann~~.~~ac.il~~/~~oca-bin/ocashort?id=4BN0 OCA].~~	+

-	==~~Reference~~==	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	~~<ref group="xtra">PMID:024419390</ref>~~<references ~~group="xtra"~~/><~~references~~/>	+	</div>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
	[[Category: Adenosylhomocysteine nucleosidase]]		[[Category: Adenosylhomocysteine nucleosidase]]
	[[Category: Campylobacter pylori]]		[[Category: Campylobacter pylori]]
-	[[Category: Davies, G J.]]	+	[[Category: Davies, G J]]
-	[[Category: Kim, R Q.]]	+	[[Category: Kim, R Q]]
-	[[Category: Offen, W A.]]	+	[[Category: Offen, W A]]
-	[[Category: Stubbs, K A.]]	+	[[Category: Stubbs, K A]]
	[[Category: Hydrolase]]		[[Category: Hydrolase]]

OCA at 05:41, 22 January 2014

OCA — Wed, 22 Jan 2014 05:41:53 GMT

←Older revision		Revision as of 05:41, 22 January 2014
Line 1:		Line 1:
	{{STRUCTURE_4bn0\| PDB=4bn0 \| SCENE= }}		{{STRUCTURE_4bn0\| PDB=4bn0 \| SCENE= }}
	===Structure of futalosine hydrolase mutant of Helicobacter pylori strain 26695===		===Structure of futalosine hydrolase mutant of Helicobacter pylori strain 26695===
		+	{{ABSTRACT_PUBMED_24419390}}

	==Function==		==Function==
Line 7:		Line 8:
	==About this Structure==		==About this Structure==
	[[4bn0]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Campylobacter_pylori Campylobacter pylori]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BN0 OCA].		[[4bn0]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Campylobacter_pylori Campylobacter pylori]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BN0 OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:024419390</ref><references group="xtra"/><references/>
	[[Category: Adenosylhomocysteine nucleosidase]]		[[Category: Adenosylhomocysteine nucleosidase]]
	[[Category: Campylobacter pylori]]		[[Category: Campylobacter pylori]]

OCA at 06:41, 15 January 2014

OCA — Wed, 15 Jan 2014 06:41:32 GMT

←Older revision		Revision as of 06:41, 15 January 2014
Line 6:		Line 6:

	==About this Structure==		==About this Structure==
-	[[4bn0]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Helicobacter_pylori_26695 Helicobacter~~ pylori ~~26695~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BN0 OCA].	+	[[4bn0]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Campylobacter_pylori Campylobacter pylori]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BN0 OCA].
	[[Category: Adenosylhomocysteine nucleosidase]]		[[Category: Adenosylhomocysteine nucleosidase]]
-	[[Category: ~~Helicobacter~~ pylori ~~26695~~]]	+	[[Category: Campylobacter pylori]]
	[[Category: Davies, G J.]]		[[Category: Davies, G J.]]
	[[Category: Kim, R Q.]]		[[Category: Kim, R Q.]]

OCA at 05:28, 12 September 2013

OCA — Thu, 12 Sep 2013 05:28:44 GMT

←Older revision		Revision as of 05:28, 12 September 2013
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	{{STRUCTURE_4bn0\| PDB=4bn0 \| SCENE= }}
		+	===Structure of futalosine hydrolase mutant of Helicobacter pylori strain 26695===

-	~~The entry 4bn0 is ON HOLD until Paper Publication~~	+	==Function==
		+	[[http://www.uniprot.org/uniprot/MTNN_HELPY MTNN_HELPY]] Responsible for cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH) (By similarity).

-	~~Authors~~: Kim, R.Q., Offen, W.A., Stubbs, K.A.~~, Davies, G.J.~~	+	==About this Structure==
-		+	[[4bn0]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Helicobacter_pylori_26695 Helicobacter pylori 26695]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BN0 OCA].
-	~~Description~~: ~~Structure of futalosine hydrolase mutant of Helicobacter pylori strain 26695~~	+	[[Category: Adenosylhomocysteine nucleosidase]]
		+	[[Category: Helicobacter pylori 26695]]
		+	[[Category: Davies, G J.]]
		+	[[Category: Kim, R Q.]]
		+	[[Category: Offen, W A.]]
		+	[[Category: Stubbs, K A.]]
		+	[[Category: Hydrolase]]

OCA: Protected "4bn0" [edit=sysop:move=sysop]

OCA — Wed, 19 Jun 2013 10:48:08 GMT

Protected "4bn0" [edit=sysop:move=sysop]

←Older revision

Revision as of 10:48, 19 June 2013

OCA: New page: '''Unreleased structure''' The entry 4bn0 is ON HOLD until Paper Publication Authors: Kim, R.Q., Offen, W.A., Stubbs, K.A., Davies, G.J. Description: Structure of futalosine hydrolase ...

OCA — Wed, 19 Jun 2013 10:48:06 GMT

New page: '''Unreleased structure''' The entry 4bn0 is ON HOLD until Paper Publication Authors: Kim, R.Q., Offen, W.A., Stubbs, K.A., Davies, G.J. Description: Structure of futalosine hydrolase ...

New page

'''Unreleased structure'''

The entry 4bn0 is ON HOLD until Paper Publication

Authors: Kim, R.Q., Offen, W.A., Stubbs, K.A., Davies, G.J.

Description: Structure of futalosine hydrolase mutant of Helicobacter pylori strain 26695