4bp0 - Revision history

OCA at 11:56, 20 December 2023

OCA — Wed, 20 Dec 2023 11:56:12 GMT

←Older revision		Revision as of 11:56, 20 December 2023
Line 3:		Line 3:
	<StructureSection load='4bp0' size='340' side='right'caption='[[4bp0]], [[Resolution\|resolution]] 2.24Å' scene=''>		<StructureSection load='4bp0' size='340' side='right'caption='[[4bp0]], [[Resolution\|resolution]] 2.24Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4bp0]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/~~"bacillus_aeruginosus"_(schroeter_1872)_trevisan_1885 "bacillus aeruginosus" (schroeter 1872) trevisan 1885~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BP0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4BP0 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4bp0]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BP0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4BP0 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene~~></td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.24Å</td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] </span></td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4bp0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bp0 OCA], [https://pdbe.org/4bp0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4bp0 RCSB], [https://www.ebi.ac.uk/pdbsum/4bp0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4bp0 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4bp0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bp0 OCA], [https://pdbe.org/4bp0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4bp0 RCSB], [https://www.ebi.ac.uk/pdbsum/4bp0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4bp0 ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/Q8G9Q0_PSEAI Q8G9Q0_PSEAI]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 24:		Line 26:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Beta-lactamase]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Brem, J~~]]	+	[[Category: Pseudomonas aeruginosa]]
-	[[Category: ~~McDonough, M A]]~~	+	[[Category: Brem J]]
-	~~[[Category: Schofield, C~~ J]]	+	[[Category: McDonough MA]]
-	[[Category: ~~Hydrolase~~]]	+	[[Category: Schofield CJ]]
-	[[Category: ~~Metallo beta lactamase~~]]	+

OCA at 07:20, 31 August 2022

OCA — Wed, 31 Aug 2022 07:20:48 GMT

←Older revision		Revision as of 07:20, 31 August 2022
Line 3:		Line 3:
	<StructureSection load='4bp0' size='340' side='right'caption='[[4bp0]], [[Resolution\|resolution]] 2.24Å' scene=''>		<StructureSection load='4bp0' size='340' side='right'caption='[[4bp0]], [[Resolution\|resolution]] 2.24Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4bp0]] is a 4 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/"bacillus_aeruginosus"_(schroeter_1872)_trevisan_1885 "bacillus aeruginosus" (schroeter 1872) trevisan 1885]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BP0 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=4BP0 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4bp0]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_aeruginosus"_(schroeter_1872)_trevisan_1885 "bacillus aeruginosus" (schroeter 1872) trevisan 1885]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BP0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4BP0 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=4bp0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bp0 OCA], [~~http~~://pdbe.org/4bp0 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4bp0 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4bp0 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4bp0 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4bp0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bp0 OCA], [https://pdbe.org/4bp0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4bp0 RCSB], [https://www.ebi.ac.uk/pdbsum/4bp0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4bp0 ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 08:15, 4 November 2020

OCA — Wed, 04 Nov 2020 08:15:08 GMT

←Older revision		Revision as of 08:15, 4 November 2020
Line 1:		Line 1:

	==Crystal structure of the closed form of Pseudomonas aeruginosa SPM-1==		==Crystal structure of the closed form of Pseudomonas aeruginosa SPM-1==
-	<StructureSection load='4bp0' size='340' side='right' caption='[[4bp0]], [[Resolution\|resolution]] 2.24Å' scene=''>	+	<StructureSection load='4bp0' size='340' side='right'caption='[[4bp0]], [[Resolution\|resolution]] 2.24Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4bp0]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_aeruginosus"_(schroeter_1872)_trevisan_1885 "bacillus aeruginosus" (schroeter 1872) trevisan 1885]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BP0 OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4BP0 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4bp0]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_aeruginosus"_(schroeter_1872)_trevisan_1885 "bacillus aeruginosus" (schroeter 1872) trevisan 1885]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BP0 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=4BP0 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4bp0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bp0 OCA], [http://pdbe.org/4bp0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4bp0 RCSB], [http://www.ebi.ac.uk/pdbsum/4bp0 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4bp0 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=4bp0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bp0 OCA], [http://pdbe.org/4bp0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4bp0 RCSB], [http://www.ebi.ac.uk/pdbsum/4bp0 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4bp0 ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 19:		Line 19:

	==See Also==		==See Also==
-	*[[Beta-lactamase\|Beta-lactamase]]	+	*[[Beta-lactamase 3D structures\|Beta-lactamase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 25:		Line 25:
	</StructureSection>		</StructureSection>
	[[Category: Beta-lactamase]]		[[Category: Beta-lactamase]]
		+	[[Category: Large Structures]]
	[[Category: Brem, J]]		[[Category: Brem, J]]
	[[Category: McDonough, M A]]		[[Category: McDonough, M A]]

OCA at 06:55, 28 March 2018

OCA — Wed, 28 Mar 2018 06:55:15 GMT

←Older revision		Revision as of 06:55, 28 March 2018
Line 3:		Line 3:
	<StructureSection load='4bp0' size='340' side='right' caption='[[4bp0]], [[Resolution\|resolution]] 2.24Å' scene=''>		<StructureSection load='4bp0' size='340' side='right' caption='[[4bp0]], [[Resolution\|resolution]] 2.24Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4bp0]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BP0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4BP0 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4bp0]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_aeruginosus"_(schroeter_1872)_trevisan_1885 "bacillus aeruginosus" (schroeter 1872) trevisan 1885]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BP0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4BP0 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] </span></td></tr>

OCA at 14:26, 29 March 2017

OCA — Wed, 29 Mar 2017 14:26:24 GMT

←Older revision		Revision as of 14:26, 29 March 2017
Line 1:		Line 1:
		+
	==Crystal structure of the closed form of Pseudomonas aeruginosa SPM-1==		==Crystal structure of the closed form of Pseudomonas aeruginosa SPM-1==
	<StructureSection load='4bp0' size='340' side='right' caption='[[4bp0]], [[Resolution\|resolution]] 2.24Å' scene=''>		<StructureSection load='4bp0' size='340' side='right' caption='[[4bp0]], [[Resolution\|resolution]] 2.24Å' scene=''>
Line 5:		Line 6:
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4bp0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bp0 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4bp0 RCSB], [http://www.ebi.ac.uk/pdbsum/4bp0 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4bp0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bp0 OCA], [http://pdbe.org/4bp0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4bp0 RCSB], [http://www.ebi.ac.uk/pdbsum/4bp0 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4bp0 ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 15:		Line 16:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 4bp0" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==

OCA at 07:04, 24 June 2015

OCA — Wed, 24 Jun 2015 07:04:01 GMT

←Older revision		Revision as of 07:04, 24 June 2015
Line 7:		Line 7:
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4bp0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bp0 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4bp0 RCSB], [http://www.ebi.ac.uk/pdbsum/4bp0 PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4bp0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bp0 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4bp0 RCSB], [http://www.ebi.ac.uk/pdbsum/4bp0 PDBsum]</span></td></tr>
	</table>		</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Metallo-beta-lactamases (MBLs) catalyse the hydrolysis of almost all beta-lactam antibiotics. We report biophysical and kinetic studies on the Sao Paulo MBL (SPM-1), which reveal its Zn(ii) ion usage and mechanism as characteristic of the clinically important di-Zn(ii) dependent B1 MBL subfamily. Biophysical analyses employing crystallography, dynamic 19F NMR and ion mobility mass spectrometry, however, reveal that SPM-1 possesses loop and mobile element regions characteristic of the B2 MBLs. These include a mobile alpha3 region which is important in catalysis and determining inhibitor selectivity. SPM-1 thus appears to be a hybrid B1/B2 MBL. The results have implications for MBL evolution and inhibitor design.
		+
		+	Studying the active-site loop movement of the Sao Paolo metallo-beta-lactamase-1daggerElectronic supplementary information (ESI) available: Procedures for protein expression and purification, F-labelling, crystallisation, data collection, and structure determination, table of crystallographic data, table of crystallographic parameters and refinement statistics, figures showing binding mode and distances, procedures for mass spectrometry measurements, differential scanning fluorimetry measurements, stopped-flow measurements and other kinetics measurements. See DOI: 10.1039/c4sc01752hClick here for additional data file.,Brem J, Struwe WB, Rydzik AM, Tarhonskaya H, Pfeffer I, Flashman E, van Berkel SS, Spencer J, Claridge TD, McDonough MA, Benesch JL, Schofield CJ Chem Sci. 2015 Feb 19;6(2):956-963. Epub 2014 Nov 4. PMID:25717359<ref>PMID:25717359</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+
		+	==See Also==
		+	*[[Beta-lactamase\|Beta-lactamase]]
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>

OCA at 14:34, 4 January 2015

OCA — Sun, 04 Jan 2015 14:34:15 GMT

←Older revision		Revision as of 14:34, 4 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4bp0]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BP0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4BP0 FirstGlance]. <br>		<table><tr><td colspan='2'>[[4bp0]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BP0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4BP0 FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] </span></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4bp0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bp0 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4bp0 RCSB], [http://www.ebi.ac.uk/pdbsum/4bp0 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4bp0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bp0 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4bp0 RCSB], [http://www.ebi.ac.uk/pdbsum/4bp0 PDBsum]</span></td></tr>
-	<table>	+	</table>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: Beta-lactamase]]		[[Category: Beta-lactamase]]
-	[[Category: Brem, J.]]	+	[[Category: Brem, J]]
-	[[Category: McDonough, M A.]]	+	[[Category: McDonough, M A]]
-	[[Category: Schofield, C J.]]	+	[[Category: Schofield, C J]]
	[[Category: Hydrolase]]		[[Category: Hydrolase]]
	[[Category: Metallo beta lactamase]]		[[Category: Metallo beta lactamase]]

OCA at 08:05, 18 June 2014

OCA — Wed, 18 Jun 2014 08:05:57 GMT

←Older revision		Revision as of 08:05, 18 June 2014
Line 1:		Line 1:
-	'''~~Unreleased structure~~'''	+	==Crystal structure of the closed form of Pseudomonas aeruginosa SPM-1==
-		+	<StructureSection load='4bp0' size='340' side='right' caption='[[4bp0]], [[Resolution\|resolution]] 2.24Å' scene=''>
-	~~The entry~~ 4bp0 is ~~ON HOLD until Paper Publication~~	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[4bp0]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BP0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4BP0 FirstGlance]. <br>
-	~~Authors~~: ~~McDonough~~, M.A., Brem, J., Schofield, C.J.	+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene><br>
-		+	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] </span></td></tr>
-	~~Description~~: ~~Crystal structure of the closed form of Pseudomonas aeruginosa SPM-1~~	+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4bp0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bp0 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4bp0 RCSB], [http://www.ebi.ac.uk/pdbsum/4bp0 PDBsum]</span></td></tr>
		+	<table>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Beta-lactamase]]
		+	[[Category: Brem, J.]]
		+	[[Category: McDonough, M A.]]
		+	[[Category: Schofield, C J.]]
		+	[[Category: Hydrolase]]
		+	[[Category: Metallo beta lactamase]]

OCA at 06:38, 6 November 2013

OCA — Wed, 06 Nov 2013 06:38:26 GMT

←Older revision		Revision as of 06:38, 6 November 2013
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 4bp0 is ON HOLD	+	The entry 4bp0 is ON HOLD until Paper Publication

	Authors: McDonough, M.A., Brem, J., Schofield, C.J.		Authors: McDonough, M.A., Brem, J., Schofield, C.J.

	Description: Crystal structure of the closed form of Pseudomonas aeruginosa SPM-1		Description: Crystal structure of the closed form of Pseudomonas aeruginosa SPM-1

OCA: Protected "4bp0" [edit=sysop:move=sysop]

OCA — Wed, 19 Jun 2013 10:51:39 GMT

Protected "4bp0" [edit=sysop:move=sysop]

←Older revision

Revision as of 10:51, 19 June 2013