4bzi - Revision history

OCA at 11:07, 9 May 2024

OCA — Thu, 09 May 2024 11:07:05 GMT

←Older revision		Revision as of 11:07, 9 May 2024
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4bzi]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BZI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4BZI FirstGlance]. <br>		<table><tr><td colspan='2'>[[4bzi]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BZI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4BZI FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GNP:PHOSPHOAMINOPHOSPHONIC+ACID-GUANYLATE+ESTER'>GNP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution\|Resolution]] 23Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GNP:PHOSPHOAMINOPHOSPHONIC+ACID-GUANYLATE+ESTER'>GNP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4bzi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bzi OCA], [https://pdbe.org/4bzi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4bzi RCSB], [https://www.ebi.ac.uk/pdbsum/4bzi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4bzi ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4bzi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bzi OCA], [https://pdbe.org/4bzi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4bzi RCSB], [https://www.ebi.ac.uk/pdbsum/4bzi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4bzi ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/SEC23_YEAST SEC23_YEAST]] Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules. SEC23 interacts with BET3 in order to target TRAPPI complex to COPII involved in internalisation of plasma membrane proteins like the maltose transporter.<ref>PMID:2670558</ref> <ref>PMID:6996832</ref> <ref>PMID:7026045</ref> <ref>PMID:3293799</ref> <ref>PMID:3049622</ref> <ref>PMID:2188733</ref> <ref>PMID:1498369</ref> <ref>PMID:7925484</ref> <ref>PMID:8451644</ref> <ref>PMID:8548805</ref> <ref>PMID:8909535</ref> <ref>PMID:9427388</ref> <ref>PMID:9023343</ref> <ref>PMID:9624457</ref> <ref>PMID:9428766</ref> <ref>PMID:10198022</ref> <ref>PMID:11086000</ref> <ref>PMID:10720463</ref> <ref>PMID:12941276</ref> <ref>PMID:14627716</ref> <ref>PMID:16269340</ref> <ref>PMID:17287728</ref>	+	[https://www.uniprot.org/uniprot/SEC23_YEAST SEC23_YEAST] Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules. SEC23 interacts with BET3 in order to target TRAPPI complex to COPII involved in internalisation of plasma membrane proteins like the maltose transporter.<ref>PMID:2670558</ref> <ref>PMID:6996832</ref> <ref>PMID:7026045</ref> <ref>PMID:3293799</ref> <ref>PMID:3049622</ref> <ref>PMID:2188733</ref> <ref>PMID:1498369</ref> <ref>PMID:7925484</ref> <ref>PMID:8451644</ref> <ref>PMID:8548805</ref> <ref>PMID:8909535</ref> <ref>PMID:9427388</ref> <ref>PMID:9023343</ref> <ref>PMID:9624457</ref> <ref>PMID:9428766</ref> <ref>PMID:10198022</ref> <ref>PMID:11086000</ref> <ref>PMID:10720463</ref> <ref>PMID:12941276</ref> <ref>PMID:14627716</ref> <ref>PMID:16269340</ref> <ref>PMID:17287728</ref>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Coat protein complex II (COPII) mediates formation of the membrane vesicles that export newly synthesised proteins from the endoplasmic reticulum. The inner COPII proteins bind to cargo and membrane, linking them to the outer COPII components that form a cage around the vesicle. Regulated flexibility in coat architecture is essential for transport of a variety of differently sized cargoes, but structural data on the assembled coat has not been available. We have used cryo-electron tomography and subtomogram averaging to determine the structure of the complete, membrane-assembled COPII coat. We describe a novel arrangement of the outer coat and find that the inner coat can assemble into regular lattices. The data reveal how coat subunits interact with one another and with the membrane, suggesting how coordinated assembly of inner and outer coats can mediate and regulate packaging of vesicles ranging from small spheres to large tubular carriers. DOI:http://dx.doi.org/10.7554/eLife.00951.001.
		+
		+	The structure of the COPII transport-vesicle coat assembled on membranes.,Zanetti G, Prinz S, Daum S, Meister A, Schekman R, Bacia K, Briggs JA Elife. 2013 Sep 17;2:e00951. doi: 10.7554/eLife.00951. PMID:24062940<ref>PMID:24062940</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	<div class="pdbe-citations 4bzi" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 17:17, 7 September 2022

OCA — Wed, 07 Sep 2022 17:17:37 GMT

←Older revision		Revision as of 17:17, 7 September 2022
Line 3:		Line 3:
	<SX load='4bzi' size='340' side='right' viewer='molstar' caption='[[4bzi]], [[Resolution\|resolution]] 23.00Å' scene=''>		<SX load='4bzi' size='340' side='right' viewer='molstar' caption='[[4bzi]], [[Resolution\|resolution]] 23.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4bzi]] is a 12 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Atcc_18824 Atcc 18824~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BZI OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=4BZI FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4bzi]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BZI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4BZI FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GNP:PHOSPHOAMINOPHOSPHONIC+ACID-GUANYLATE+ESTER'>GNP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GNP:PHOSPHOAMINOPHOSPHONIC+ACID-GUANYLATE+ESTER'>GNP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4bzj\|4bzj]], [[4bzk\|4bzk]]</td></tr>~~	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4bzi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bzi OCA], [https://pdbe.org/4bzi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4bzi RCSB], [https://www.ebi.ac.uk/pdbsum/4bzi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4bzi ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=4bzi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bzi OCA], [~~http~~://pdbe.org/4bzi PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4bzi RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4bzi PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4bzi ProSAT]</span></td></tr>	+
	</table>		</table>
-	~~<div style~~=~~"background-color:#fffaf0;">~~	+	== Function ==
-	=~~= Publication Abstract from PubMed~~ ==	+	[[https://www.uniprot.org/uniprot/SEC23_YEAST SEC23_YEAST]] Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules. SEC23 interacts with BET3 in order to target TRAPPI complex to COPII involved in internalisation of plasma membrane proteins like the maltose transporter.<ref>PMID:2670558</ref> <ref>PMID:6996832</ref> <ref>PMID:7026045</ref> <ref>PMID:3293799</ref> <ref>PMID:3049622</ref> <ref>PMID:2188733</ref> <ref>PMID:1498369</ref> <ref>PMID:7925484</ref> <ref>PMID:8451644</ref> <ref>PMID:8548805</ref> <ref>PMID:8909535</ref> <ref>PMID:9427388</ref> <ref>PMID:9023343</ref> <ref>PMID:9624457</ref> <ref>PMID:9428766</ref> <ref>PMID:10198022</ref> <ref>PMID:11086000</ref> <ref>PMID:10720463</ref> <ref>PMID:12941276</ref> <ref>PMID:14627716</ref> <ref>PMID:16269340</ref> <ref>PMID:17287728</ref>
-	~~Coat~~ protein complex II (COPII) ~~mediates~~ formation of ~~the membrane~~ vesicles ~~that export newly synthesised proteins~~ from the endoplasmic reticulum. The ~~inner COPII proteins bind to cargo and membrane, linking them to the outer COPII components that form a cage around the vesicle. Regulated flexibility in~~ coat ~~architecture is essential for transport of a variety of differently sized cargoes~~, ~~but structural data on~~ the ~~assembled coat has not been available. We have used cryo-electron tomography and subtomogram averaging to determine the structure~~ of the ~~complete,~~ membrane~~-assembled COPII coat. We describe a novel arrangement of the outer coat and find that the inner coat can assemble~~ into ~~regular lattices. The data reveal how coat subunits interact with one another~~ and ~~with~~ the ~~membrane, suggesting how coordinated assembly~~ of ~~inner and outer coats can mediate and regulate packaging of vesicles ranging from small spheres~~ to ~~large tubular carriers~~. ~~DOI~~:~~http~~://~~dx.doi.org~~/~~10.7554~~/~~eLife.00951.001.~~	+
-		+
-	~~The structure of the COPII transport-vesicle coat assembled on membranes.,Zanetti G, Prinz S, Daum S, Meister A, Schekman R, Bacia K, Briggs JA Elife. 2013 Sep 17;2~~:~~e00951. doi~~: ~~10.7554~~/~~eLife.00951.~~ PMID:~~24062940~~<ref>PMID:~~24062940~~</ref>	+
-		+
-	~~From MEDLINE®~~/~~PubMed®, a database of the U.S. National Library of Medicine.~~<br>	+
-	</~~div~~>	+
-	<~~div class="pdbe-citations 4bzi" style="background-color~~:~~#fffaf0;"~~></~~div~~>	+
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</SX>		</SX>
-	[[Category: Atcc 18824]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Bacia, K]]	+	[[Category: Saccharomyces cerevisiae]]
-	[[Category: Briggs~~, J A.G~~]]	+	[[Category: Bacia K]]
-	[[Category: Daum, S]]	+	[[Category: Briggs JAG]]
-	[[Category: Meister, A]]	+	[[Category: Daum S]]
-	[[Category: Prinz, S]]	+	[[Category: Meister A]]
-	[[Category: Schekman, R]]	+	[[Category: Prinz S]]
-	[[Category: Zanetti, G]]	+	[[Category: Schekman R]]
-	~~[[Category: Sar1]]~~	+	[[Category: Zanetti G]]
-	~~[[Category: Sec23]]~~	+
-	~~[[Category: Sec24]]~~	+
-	~~[[Category: Secretion]]~~	+
-	~~[[Category: Trafficking]]~~	+
-	~~[[Category: Transport protein~~]]	+

OCA at 18:58, 10 April 2020

OCA — Fri, 10 Apr 2020 18:58:08 GMT

←Older revision		Revision as of 18:58, 10 April 2020
Line 3:		Line 3:
	<SX load='4bzi' size='340' side='right' viewer='molstar' caption='[[4bzi]], [[Resolution\|resolution]] 23.00Å' scene=''>		<SX load='4bzi' size='340' side='right' viewer='molstar' caption='[[4bzi]], [[Resolution\|resolution]] 23.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4bzi]] is a 12 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_18824 Atcc 18824]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BZI OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4BZI FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4bzi]] is a 12 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_18824 Atcc 18824]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BZI OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=4BZI FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GNP:PHOSPHOAMINOPHOSPHONIC+ACID-GUANYLATE+ESTER'>GNP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GNP:PHOSPHOAMINOPHOSPHONIC+ACID-GUANYLATE+ESTER'>GNP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4bzj\|4bzj]], [[4bzk\|4bzk]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4bzj\|4bzj]], [[4bzk\|4bzk]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4bzi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bzi OCA], [http://pdbe.org/4bzi PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4bzi RCSB], [http://www.ebi.ac.uk/pdbsum/4bzi PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4bzi ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=4bzi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bzi OCA], [http://pdbe.org/4bzi PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4bzi RCSB], [http://www.ebi.ac.uk/pdbsum/4bzi PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4bzi ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 17:51, 6 March 2020

OCA — Fri, 06 Mar 2020 17:51:38 GMT

←Older revision		Revision as of 17:51, 6 March 2020
Line 1:		Line 1:

	==The structure of the COPII coat assembled on membranes==		==The structure of the COPII coat assembled on membranes==
-	<~~StructureSection~~ load='4bzi' size='340' side='right' caption='[[4bzi]], [[Resolution\|resolution]] 23.00Å' scene=''>	+	<SX load='4bzi' size='340' side='right' viewer='molstar' caption='[[4bzi]], [[Resolution\|resolution]] 23.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4bzi]] is a 12 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_18824 Atcc 18824]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BZI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4BZI FirstGlance]. <br>		<table><tr><td colspan='2'>[[4bzi]] is a 12 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_18824 Atcc 18824]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BZI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4BZI FirstGlance]. <br>
Line 20:		Line 20:
	<references/>		<references/>
	__TOC__		__TOC__
-	</~~StructureSection~~>	+	</SX>
	[[Category: Atcc 18824]]		[[Category: Atcc 18824]]
		+	[[Category: Large Structures]]
	[[Category: Bacia, K]]		[[Category: Bacia, K]]
	[[Category: Briggs, J A.G]]		[[Category: Briggs, J A.G]]

OCA at 06:09, 20 June 2018

OCA — Wed, 20 Jun 2018 06:09:13 GMT

←Older revision		Revision as of 06:09, 20 June 2018
Line 6:		Line 6:
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GNP:PHOSPHOAMINOPHOSPHONIC+ACID-GUANYLATE+ESTER'>GNP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GNP:PHOSPHOAMINOPHOSPHONIC+ACID-GUANYLATE+ESTER'>GNP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4bzj\|4bzj]], [[4bzk\|4bzk]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4bzj\|4bzj]], [[4bzk\|4bzk]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4bzi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bzi OCA], [http://pdbe.org/4bzi PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4bzi RCSB], [http://www.ebi.ac.uk/pdbsum/4bzi PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4bzi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bzi OCA], [http://pdbe.org/4bzi PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4bzi RCSB], [http://www.ebi.ac.uk/pdbsum/4bzi PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4bzi ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 04:40, 11 May 2016

OCA — Wed, 11 May 2016 04:40:19 GMT

←Older revision		Revision as of 04:40, 11 May 2016
Line 1:		Line 1:
		+
	==The structure of the COPII coat assembled on membranes==		==The structure of the COPII coat assembled on membranes==
	<StructureSection load='4bzi' size='340' side='right' caption='[[4bzi]], [[Resolution\|resolution]] 23.00Å' scene=''>		<StructureSection load='4bzi' size='340' side='right' caption='[[4bzi]], [[Resolution\|resolution]] 23.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4bzi]] is a 12 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Saccharomyces_cerevisiae Saccharomyces cerevisiae~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BZI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4BZI FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4bzi]] is a 12 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_18824 Atcc 18824]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BZI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4BZI FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GNP:PHOSPHOAMINOPHOSPHONIC+ACID-GUANYLATE+ESTER'>GNP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GNP:PHOSPHOAMINOPHOSPHONIC+ACID-GUANYLATE+ESTER'>GNP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4bzj\|4bzj]], [[4bzk\|4bzk]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4bzj\|4bzj]], [[4bzk\|4bzk]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4bzi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bzi OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4bzi RCSB], [http://www.ebi.ac.uk/pdbsum/4bzi PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4bzi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bzi OCA], [http://pdbe.org/4bzi PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4bzi RCSB], [http://www.ebi.ac.uk/pdbsum/4bzi PDBsum]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 15:		Line 16:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 4bzi" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Saccharomyces cerevisiae~~]]	+	[[Category: Atcc 18824]]
	[[Category: Bacia, K]]		[[Category: Bacia, K]]
	[[Category: Briggs, J A.G]]		[[Category: Briggs, J A.G]]

OCA at 08:47, 21 December 2014

OCA — Sun, 21 Dec 2014 08:47:23 GMT

←Older revision		Revision as of 08:47, 21 December 2014
Line 1:		Line 1:
-	~~{{STRUCTURE_4bzi\| PDB=4bzi \| SCENE= }}~~	+	==The structure of the COPII coat assembled on membranes==
-	===The structure of the COPII coat assembled on membranes===	+	<StructureSection load='4bzi' size='340' side='right' caption='[[4bzi]], [[Resolution\|resolution]] 23.00Å' scene=''>
-	~~{{ABSTRACT_PUBMED_24062940}}~~	+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[4bzi]] is a 12 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BZI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4BZI FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GNP:PHOSPHOAMINOPHOSPHONIC+ACID-GUANYLATE+ESTER'>GNP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4bzj\|4bzj]], [[4bzk\|4bzk]]</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4bzi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bzi OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4bzi RCSB], [http://www.ebi.ac.uk/pdbsum/4bzi PDBsum]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Coat protein complex II (COPII) mediates formation of the membrane vesicles that export newly synthesised proteins from the endoplasmic reticulum. The inner COPII proteins bind to cargo and membrane, linking them to the outer COPII components that form a cage around the vesicle. Regulated flexibility in coat architecture is essential for transport of a variety of differently sized cargoes, but structural data on the assembled coat has not been available. We have used cryo-electron tomography and subtomogram averaging to determine the structure of the complete, membrane-assembled COPII coat. We describe a novel arrangement of the outer coat and find that the inner coat can assemble into regular lattices. The data reveal how coat subunits interact with one another and with the membrane, suggesting how coordinated assembly of inner and outer coats can mediate and regulate packaging of vesicles ranging from small spheres to large tubular carriers. DOI:http://dx.doi.org/10.7554/eLife.00951.001.

-	~~==About this Structure==~~	+	The structure of the COPII transport-vesicle coat assembled on membranes.,Zanetti G, Prinz S, Daum S, Meister A, Schekman R, Bacia K, Briggs JA Elife. 2013 Sep 17;2:e00951. doi: 10.7554/eLife.00951. PMID:24062940<ref>PMID:24062940</ref>
-	~~[[4bzi]] is a 12 chain~~ structure ~~with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]~~. ~~Full crystallographic information is available from [http~~:/~~/oca~~.~~weizmann~~.~~ac.il~~/~~oca-bin/ocashort?id=4BZI OCA].~~	+

-	==~~Reference~~==	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	~~<ref group="xtra">PMID:024062940</ref>~~<references ~~group="xtra"~~/><~~references~~/>	+	</div>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
	[[Category: Saccharomyces cerevisiae]]		[[Category: Saccharomyces cerevisiae]]
-	[[Category: Bacia, K.]]	+	[[Category: Bacia, K]]
-	[[Category: Briggs, J A.G.]]	+	[[Category: Briggs, J A.G]]
-	[[Category: Daum, S.]]	+	[[Category: Daum, S]]
-	[[Category: Meister, A.]]	+	[[Category: Meister, A]]
-	[[Category: Prinz, S.]]	+	[[Category: Prinz, S]]
-	[[Category: Schekman, R.]]	+	[[Category: Schekman, R]]
-	[[Category: Zanetti, G.]]	+	[[Category: Zanetti, G]]
	[[Category: Sar1]]		[[Category: Sar1]]
	[[Category: Sec23]]		[[Category: Sec23]]

OCA at 05:07, 23 October 2013

OCA — Wed, 23 Oct 2013 05:07:41 GMT

←Older revision		Revision as of 05:07, 23 October 2013
Line 1:		Line 1:
	{{STRUCTURE_4bzi\| PDB=4bzi \| SCENE= }}		{{STRUCTURE_4bzi\| PDB=4bzi \| SCENE= }}
	===The structure of the COPII coat assembled on membranes===		===The structure of the COPII coat assembled on membranes===
		+	{{ABSTRACT_PUBMED_24062940}}

	==About this Structure==		==About this Structure==
	[[4bzi]] is a 12 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BZI OCA].		[[4bzi]] is a 12 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BZI OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:024062940</ref><references group="xtra"/><references/>
	[[Category: Saccharomyces cerevisiae]]		[[Category: Saccharomyces cerevisiae]]
	[[Category: Bacia, K.]]		[[Category: Bacia, K.]]

OCA at 04:18, 20 September 2013

OCA — Fri, 20 Sep 2013 04:18:25 GMT

←Older revision		Revision as of 04:18, 20 September 2013
Line 1:		Line 1:
-	~~'''Unreleased~~ structure~~'''~~	+	{{STRUCTURE_4bzi\| PDB=4bzi \| SCENE= }}
		+	===The structure of the COPII coat assembled on membranes===

-	~~The entry~~ 4bzi is ~~ON HOLD until Paper Publication~~	+	==About this Structure==
-		+	[[4bzi]] is a 12 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BZI OCA].
-	~~Authors~~: ~~Zanetti~~, G., ~~Prinz, S~~., Daum, S., Meister, A., Schekman, R., ~~Bacia, K., Briggs, J.A.~~G.	+	[[Category: Saccharomyces cerevisiae]]
-		+	[[Category: Bacia, K.]]
-	~~Description~~: ~~The structure of the COPII coat assembled on membranes~~	+	[[Category: Briggs, J A.G.]]
		+	[[Category: Daum, S.]]
		+	[[Category: Meister, A.]]
		+	[[Category: Prinz, S.]]
		+	[[Category: Schekman, R.]]
		+	[[Category: Zanetti, G.]]
		+	[[Category: Sar1]]
		+	[[Category: Sec23]]
		+	[[Category: Sec24]]
		+	[[Category: Secretion]]
		+	[[Category: Trafficking]]
		+	[[Category: Transport protein]]

OCA at 07:36, 21 August 2013

OCA — Wed, 21 Aug 2013 07:36:22 GMT

←Older revision		Revision as of 07:36, 21 August 2013
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 4bzi is ON HOLD	+	The entry 4bzi is ON HOLD until Paper Publication

	Authors: Zanetti, G., Prinz, S., Daum, S., Meister, A., Schekman, R., Bacia, K., Briggs, J.A.G.		Authors: Zanetti, G., Prinz, S., Daum, S., Meister, A., Schekman, R., Bacia, K., Briggs, J.A.G.

	Description: The structure of the COPII coat assembled on membranes		Description: The structure of the COPII coat assembled on membranes