4c8z - Revision history

OCA at 12:06, 20 December 2023

OCA — Wed, 20 Dec 2023 12:06:03 GMT

←Older revision		Revision as of 12:06, 20 December 2023
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4c8z]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus_HB8 Thermus thermophilus HB8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4C8Z OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4C8Z FirstGlance]. <br>		<table><tr><td colspan='2'>[[4c8z]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus_HB8 Thermus thermophilus HB8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4C8Z OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4C8Z FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=23G:GUANOSINE-5-PHOSPHATE-2,3-CYCLIC+PHOSPHATE'>23G</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.503Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=23G:GUANOSINE-5-PHOSPHATE-2,3-CYCLIC+PHOSPHATE'>23G</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4c8z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4c8z OCA], [https://pdbe.org/4c8z PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4c8z RCSB], [https://www.ebi.ac.uk/pdbsum/4c8z PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4c8z ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4c8z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4c8z OCA], [https://pdbe.org/4c8z PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4c8z RCSB], [https://www.ebi.ac.uk/pdbsum/4c8z PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4c8z ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/Q5SM65_THET8 Q5SM65_THET8]]	+	[https://www.uniprot.org/uniprot/Q5SM65_THET8 Q5SM65_THET8]
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	In many bacteria and archaea, small RNAs derived from clustered regularly interspaced short palindromic repeats (CRISPRs) associate with CRISPR-associated (Cas) proteins to target foreign DNA for destruction. In Type I and III CRISPR/Cas systems, the Cas6 family of endoribonucleases generates functional CRISPR-derived RNAs by site-specific cleavage of repeat sequences in precursor transcripts. CRISPR repeats differ widely in both sequence and structure, with varying propensity to form hairpin folds immediately preceding the cleavage site. To investigate the evolution of distinct mechanisms for the recognition of diverse CRISPR repeats by Cas6 enzymes, we determined crystal structures of two Thermus thermophilus Cas6 enzymes both alone and bound to substrate and product RNAs. These structures show how the scaffold common to all Cas6 endonucleases has evolved two binding sites with distinct modes of RNA recognition: one specific for a hairpin fold and the other for a single-stranded 5'-terminal segment preceding the hairpin. These findings explain how divergent Cas6 enzymes have emerged to mediate highly selective pre-CRISPR-derived RNA processing across diverse CRISPR systems.
		+
		+	Evolution of CRISPR RNA recognition and processing by Cas6 endonucleases.,Niewoehner O, Jinek M, Doudna JA Nucleic Acids Res. 2013 Oct 22. PMID:24150936<ref>PMID:24150936</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	<div class="pdbe-citations 4c8z" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
	*[[CRISPR-Cas Part II\|CRISPR-Cas Part II]]		*[[CRISPR-Cas Part II\|CRISPR-Cas Part II]]
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>

OCA at 17:32, 7 September 2022

OCA — Wed, 07 Sep 2022 17:32:42 GMT

←Older revision		Revision as of 17:32, 7 September 2022
Line 3:		Line 3:
	<StructureSection load='4c8z' size='340' side='right'caption='[[4c8z]], [[Resolution\|resolution]] 2.50Å' scene=''>		<StructureSection load='4c8z' size='340' side='right'caption='[[4c8z]], [[Resolution\|resolution]] 2.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4c8z]] is a 3 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Thet8 Thet8~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4C8Z OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4C8Z FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4c8z]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus_HB8 Thermus thermophilus HB8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4C8Z OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4C8Z FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=K:~~POTASSIUM~~+~~ION~~'>K</scene>, <scene name='pdbligand=~~SO4~~:~~SULFATE~~+ION'>~~SO4~~</scene>~~</td></tr>~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=23G:GUANOSINE-5-PHOSPHATE-2,3-CYCLIC+PHOSPHATE'>23G</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	~~<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat">~~<scene name='pdbligand=~~23G~~:~~GUANOSINE-5-PHOSPHATE-2,3-CYCLIC~~+~~PHOSPHATE~~'>~~23G~~</scene>~~</td></tr>~~	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4c8z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4c8z OCA], [https://pdbe.org/4c8z PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4c8z RCSB], [https://www.ebi.ac.uk/pdbsum/4c8z PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4c8z ProSAT]</span></td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4c8y\|4c8y]], [[4c97\|4c97]], [[4c98\|4c98]], [[4c9d\|4c9d]]~~</td></tr>	+
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4c8z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4c8z OCA], [~~http~~://pdbe.org/4c8z PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4c8z RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4c8z PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4c8z ProSAT]</span></td></tr>	+
	</table>		</table>
-	~~<div style~~=~~"background-color:#fffaf0;">~~	+	== Function ==
-	=~~= Publication Abstract from PubMed~~ ==	+	[[https://www.uniprot.org/uniprot/Q5SM65_THET8 Q5SM65_THET8]]
-	In many bacteria and archaea, small RNAs derived from clustered regularly interspaced short palindromic repeats (CRISPRs) associate with CRISPR-associated (Cas) proteins to target foreign DNA for destruction. In Type I and III CRISPR/Cas systems, the Cas6 family of endoribonucleases generates functional CRISPR-derived RNAs by site-specific cleavage of repeat sequences in precursor transcripts. CRISPR repeats differ widely in both sequence and structure, with varying propensity to form hairpin folds immediately preceding the cleavage site. To investigate the evolution of distinct mechanisms for the recognition of diverse CRISPR repeats by Cas6 enzymes, we determined crystal structures of two Thermus thermophilus Cas6 enzymes both alone and bound to substrate and product RNAs. These structures show how the scaffold common to all Cas6 endonucleases has evolved two binding sites with distinct modes of RNA recognition: one specific for a hairpin fold and the other for a single-stranded 5'-terminal segment preceding the hairpin. These findings explain how divergent Cas6 enzymes have emerged to mediate highly selective pre-CRISPR-derived RNA processing across diverse CRISPR systems.	+
-		+
-	~~Evolution of CRISPR RNA recognition and processing by Cas6 endonucleases.,Niewoehner O, Jinek M, Doudna JA Nucleic Acids Res. 2013 Oct 22. PMID:24150936<ref>PMID:24150936<~~/~~ref>~~	+
-		+
-	~~From MEDLINE®~~/~~PubMed®, a database of the U~~.S. ~~National Library of Medicine.<br>~~	+
-	</~~div>~~	+
-	~~<div class="pdbe-citations 4c8z" style="background-color:#fffaf0;"><~~/~~div>~~	+

	==See Also==		==See Also==
	*[[CRISPR-Cas Part II\|CRISPR-Cas Part II]]		*[[CRISPR-Cas Part II\|CRISPR-Cas Part II]]
-	== References ==
-	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Thet8~~]]	+	[[Category: Thermus thermophilus HB8]]
-	[[Category: Doudna~~, J A~~]]	+	[[Category: Doudna JA]]
-	[[Category: Jinek, M]]	+	[[Category: Jinek M]]
-	[[Category: Niewoehner, O]]	+	[[Category: Niewoehner O]]
-	~~[[Category: Crispr cas protein]]~~	+
-	~~[[Category: Hydrolase-rna complex]]~~	+
-	~~[[Category: Rna processing ribonuclease~~]]	+

OCA at 09:27, 20 March 2019

OCA — Wed, 20 Mar 2019 09:27:52 GMT

←Older revision		Revision as of 09:27, 20 March 2019
Line 1:		Line 1:

	==Cas6 (TTHA0078) product complex==		==Cas6 (TTHA0078) product complex==
-	<StructureSection load='4c8z' size='340' side='right' caption='[[4c8z]], [[Resolution\|resolution]] 2.50Å' scene=''>	+	<StructureSection load='4c8z' size='340' side='right'caption='[[4c8z]], [[Resolution\|resolution]] 2.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4c8z]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Thet8 Thet8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4C8Z OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4C8Z FirstGlance]. <br>		<table><tr><td colspan='2'>[[4c8z]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Thet8 Thet8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4C8Z OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4C8Z FirstGlance]. <br>
Line 18:		Line 18:
	</div>		</div>
	<div class="pdbe-citations 4c8z" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 4c8z" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[CRISPR-Cas Part II\|CRISPR-Cas Part II]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Thet8]]		[[Category: Thet8]]
	[[Category: Doudna, J A]]		[[Category: Doudna, J A]]

OCA at 15:30, 11 August 2016

OCA — Thu, 11 Aug 2016 15:30:59 GMT

←Older revision		Revision as of 15:30, 11 August 2016
Line 1:		Line 1:
		+
	==Cas6 (TTHA0078) product complex==		==Cas6 (TTHA0078) product complex==
	<StructureSection load='4c8z' size='340' side='right' caption='[[4c8z]], [[Resolution\|resolution]] 2.50Å' scene=''>		<StructureSection load='4c8z' size='340' side='right' caption='[[4c8z]], [[Resolution\|resolution]] 2.50Å' scene=''>
Line 6:		Line 7:
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=23G:GUANOSINE-5-PHOSPHATE-2,3-CYCLIC+PHOSPHATE'>23G</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=23G:GUANOSINE-5-PHOSPHATE-2,3-CYCLIC+PHOSPHATE'>23G</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4c8y\|4c8y]], [[4c97\|4c97]], [[4c98\|4c98]], [[4c9d\|4c9d]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4c8y\|4c8y]], [[4c97\|4c97]], [[4c98\|4c98]], [[4c9d\|4c9d]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4c8z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4c8z OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4c8z RCSB], [http://www.ebi.ac.uk/pdbsum/4c8z PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4c8z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4c8z OCA], [http://pdbe.org/4c8z PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4c8z RCSB], [http://www.ebi.ac.uk/pdbsum/4c8z PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4c8z ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 16:		Line 17:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 4c8z" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 12:53, 5 January 2015

OCA — Mon, 05 Jan 2015 12:53:36 GMT

←Older revision		Revision as of 12:53, 5 January 2015
Line 1:		Line 1:
-	~~{{STRUCTURE_4c8z~~\| ~~PDB~~=4c8z \| ~~SCENE~~= }}	+	==Cas6 (TTHA0078) product complex==
-	===~~Cas6 (TTHA0078) product complex~~===	+	<StructureSection load='4c8z' size='340' side='right' caption='[[4c8z]], [[Resolution\|resolution]] 2.50Å' scene=''>
-	~~{{ABSTRACT_PUBMED_24150936}}~~	+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[4c8z]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Thet8 Thet8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4C8Z OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4C8Z FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
		+	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=23G:GUANOSINE-5-PHOSPHATE-2,3-CYCLIC+PHOSPHATE'>23G</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4c8y\|4c8y]], [[4c97\|4c97]], [[4c98\|4c98]], [[4c9d\|4c9d]]</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4c8z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4c8z OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4c8z RCSB], [http://www.ebi.ac.uk/pdbsum/4c8z PDBsum]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	In many bacteria and archaea, small RNAs derived from clustered regularly interspaced short palindromic repeats (CRISPRs) associate with CRISPR-associated (Cas) proteins to target foreign DNA for destruction. In Type I and III CRISPR/Cas systems, the Cas6 family of endoribonucleases generates functional CRISPR-derived RNAs by site-specific cleavage of repeat sequences in precursor transcripts. CRISPR repeats differ widely in both sequence and structure, with varying propensity to form hairpin folds immediately preceding the cleavage site. To investigate the evolution of distinct mechanisms for the recognition of diverse CRISPR repeats by Cas6 enzymes, we determined crystal structures of two Thermus thermophilus Cas6 enzymes both alone and bound to substrate and product RNAs. These structures show how the scaffold common to all Cas6 endonucleases has evolved two binding sites with distinct modes of RNA recognition: one specific for a hairpin fold and the other for a single-stranded 5'-terminal segment preceding the hairpin. These findings explain how divergent Cas6 enzymes have emerged to mediate highly selective pre-CRISPR-derived RNA processing across diverse CRISPR systems.

-	~~==About this Structure==~~	+	Evolution of CRISPR RNA recognition and processing by Cas6 endonucleases.,Niewoehner O, Jinek M, Doudna JA Nucleic Acids Res. 2013 Oct 22. PMID:24150936<ref>PMID:24150936</ref>
-	~~[[4c8z]] is a 3 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Thet8 Thet8]~~. ~~Full crystallographic information is available from [http~~:/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=4C8Z OCA].~~	+

-	==~~Reference~~==	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	~~<ref group="xtra">PMID:024150936</ref>~~<references ~~group="xtra"~~/><~~references~~/>	+	</div>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
	[[Category: Thet8]]		[[Category: Thet8]]
-	[[Category: Doudna, J A.]]	+	[[Category: Doudna, J A]]
-	[[Category: Jinek, M.]]	+	[[Category: Jinek, M]]
-	[[Category: Niewoehner, O.]]	+	[[Category: Niewoehner, O]]
	[[Category: Crispr cas protein]]		[[Category: Crispr cas protein]]
	[[Category: Hydrolase-rna complex]]		[[Category: Hydrolase-rna complex]]
	[[Category: Rna processing ribonuclease]]		[[Category: Rna processing ribonuclease]]

OCA at 11:40, 20 November 2013

OCA — Wed, 20 Nov 2013 11:40:16 GMT

←Older revision		Revision as of 11:40, 20 November 2013
Line 4:		Line 4:

	==About this Structure==		==About this Structure==
-	[[4c8z]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Thermus_thermophilus_hb8 Thermus thermophilus hb8~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4C8Z OCA].	+	[[4c8z]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Thet8 Thet8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4C8Z OCA].

	==Reference==		==Reference==
	<ref group="xtra">PMID:024150936</ref><references group="xtra"/><references/>		<ref group="xtra">PMID:024150936</ref><references group="xtra"/><references/>
-	[[Category: ~~Thermus thermophilus hb8~~]]	+	[[Category: Thet8]]
	[[Category: Doudna, J A.]]		[[Category: Doudna, J A.]]
	[[Category: Jinek, M.]]		[[Category: Jinek, M.]]

OCA at 07:38, 6 November 2013

OCA — Wed, 06 Nov 2013 07:38:57 GMT

←Older revision		Revision as of 07:38, 6 November 2013
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	{{STRUCTURE_4c8z\| PDB=4c8z \| SCENE= }}
		+	===Cas6 (TTHA0078) product complex===
		+	{{ABSTRACT_PUBMED_24150936}}

-	~~The entry~~ 4c8z is ~~ON HOLD~~	+	==About this Structure==
		+	[[4c8z]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus_hb8 Thermus thermophilus hb8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4C8Z OCA].

-	~~Authors~~: Jinek, M., Niewoehner, O.~~, Doudna, J.A.~~	+	==Reference==
-		+	<ref group="xtra">PMID:024150936</ref><references group="xtra"/><references/>
-	~~Description~~: ~~Cas6 (TTHA0078) product~~ complex	+	[[Category: Thermus thermophilus hb8]]
		+	[[Category: Doudna, J A.]]
		+	[[Category: Jinek, M.]]
		+	[[Category: Niewoehner, O.]]
		+	[[Category: Crispr cas protein]]
		+	[[Category: Hydrolase-rna complex]]
		+	[[Category: Rna processing ribonuclease]]

OCA: Protected "4c8z" [edit=sysop:move=sysop]

OCA — Thu, 10 Oct 2013 05:28:40 GMT

Protected "4c8z" [edit=sysop:move=sysop]

←Older revision

Revision as of 05:28, 10 October 2013

OCA: New page: '''Unreleased structure''' The entry 4c8z is ON HOLD Authors: Jinek, M., Niewoehner, O., Doudna, J.A. Description: Cas6 (TTHA0078) product complex

OCA — Thu, 10 Oct 2013 05:28:39 GMT

New page: '''Unreleased structure''' The entry 4c8z is ON HOLD Authors: Jinek, M., Niewoehner, O., Doudna, J.A. Description: Cas6 (TTHA0078) product complex

New page

'''Unreleased structure'''

The entry 4c8z is ON HOLD

Authors: Jinek, M., Niewoehner, O., Doudna, J.A.

Description: Cas6 (TTHA0078) product complex