4cio - Revision history

OCA at 07:17, 14 September 2022

OCA — Wed, 14 Sep 2022 07:17:09 GMT

←Older revision		Revision as of 07:17, 14 September 2022
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	==RRM domain from C. elegans SUP-12 bound to GGUGUGC RNA==		==RRM domain from C. elegans SUP-12 bound to GGUGUGC RNA==
-	<StructureSection load='4cio' size='340' side='right'caption='[[4cio~~]], [[NMR_Ensembles_of_Models \| 15 NMR models~~]]' scene=''>	+	<StructureSection load='4cio' size='340' side='right'caption='[[4cio]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4cio]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Caeel Caeel~~]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CIO OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4CIO FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4cio]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Caenorhabditis_elegans Caenorhabditis elegans]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CIO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4CIO FirstGlance]. <br>
-	</td></tr>~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4ch0\|4ch0]], [[4ch1\|4ch1]]</td></tr>~~	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4cio FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4cio OCA], [https://pdbe.org/4cio PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4cio RCSB], [https://www.ebi.ac.uk/pdbsum/4cio PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4cio ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4cio FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4cio OCA], [~~http~~://pdbe.org/4cio PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4cio RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4cio PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4cio ProSAT]</span></td></tr>	+
	</table>		</table>
		+	== Function ==
		+	[[https://www.uniprot.org/uniprot/O45189_CAEEL O45189_CAEEL]]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Caeel~~]]	+	[[Category: Caenorhabditis elegans]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Amrane, S]]	+	[[Category: Amrane S]]
-	[[Category: Mackereth~~, C D]]~~	+	[[Category: Mackereth CD]]
-	~~[[Category: Development]]~~	+
-	~~[[Category: Muscle]]~~	+
-	~~[[Category: Rna binding protein-rna complex~~]]	+

OCA at 09:23, 20 March 2019

OCA — Wed, 20 Mar 2019 09:23:27 GMT

←Older revision		Revision as of 09:23, 20 March 2019
Line 1:		Line 1:

	==RRM domain from C. elegans SUP-12 bound to GGUGUGC RNA==		==RRM domain from C. elegans SUP-12 bound to GGUGUGC RNA==
-	<StructureSection load='4cio' size='340' side='right' caption='[[4cio]], [[NMR_Ensembles_of_Models \| 15 NMR models]]' scene=''>	+	<StructureSection load='4cio' size='340' side='right'caption='[[4cio]], [[NMR_Ensembles_of_Models \| 15 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4cio]] is a 2 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CIO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4CIO FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4cio]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Caeel Caeel]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CIO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4CIO FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4ch0\|4ch0]], [[4ch1\|4ch1]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4ch0\|4ch0]], [[4ch1\|4ch1]]</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4cio FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4cio OCA], [http://pdbe.org/4cio PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4cio RCSB], [http://www.ebi.ac.uk/pdbsum/4cio PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4cio ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4cio FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4cio OCA], [http://pdbe.org/4cio PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4cio RCSB], [http://www.ebi.ac.uk/pdbsum/4cio PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4cio ProSAT]</span></td></tr>
Line 20:		Line 20:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Caeel]]
		+	[[Category: Large Structures]]
	[[Category: Amrane, S]]		[[Category: Amrane, S]]
	[[Category: Mackereth, C D]]		[[Category: Mackereth, C D]]

OCA at 07:11, 23 December 2016

OCA — Fri, 23 Dec 2016 07:11:05 GMT

←Older revision		Revision as of 07:11, 23 December 2016
Line 1:		Line 1:
		+
	==RRM domain from C. elegans SUP-12 bound to GGUGUGC RNA==		==RRM domain from C. elegans SUP-12 bound to GGUGUGC RNA==
	<StructureSection load='4cio' size='340' side='right' caption='[[4cio]], [[NMR_Ensembles_of_Models \| 15 NMR models]]' scene=''>		<StructureSection load='4cio' size='340' side='right' caption='[[4cio]], [[NMR_Ensembles_of_Models \| 15 NMR models]]' scene=''>
Line 4:		Line 5:
	<table><tr><td colspan='2'>[[4cio]] is a 2 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CIO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4CIO FirstGlance]. <br>		<table><tr><td colspan='2'>[[4cio]] is a 2 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CIO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4CIO FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4ch0\|4ch0]], [[4ch1\|4ch1]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4ch0\|4ch0]], [[4ch1\|4ch1]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4cio FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4cio OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4cio RCSB], [http://www.ebi.ac.uk/pdbsum/4cio PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4cio FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4cio OCA], [http://pdbe.org/4cio PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4cio RCSB], [http://www.ebi.ac.uk/pdbsum/4cio PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4cio ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 14:		Line 15:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 4cio" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 08:12, 20 January 2015

OCA — Tue, 20 Jan 2015 08:12:52 GMT

←Older revision		Revision as of 08:12, 20 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4cio]] is a 2 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CIO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4CIO FirstGlance]. <br>		<table><tr><td colspan='2'>[[4cio]] is a 2 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CIO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4CIO FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4ch0\|4ch0]], [[4ch1\|4ch1]]</td></tr>	+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4ch0\|4ch0]], [[4ch1\|4ch1]]</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4cio FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4cio OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4cio RCSB], [http://www.ebi.ac.uk/pdbsum/4cio PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4cio FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4cio OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4cio RCSB], [http://www.ebi.ac.uk/pdbsum/4cio PDBsum]</span></td></tr>
-	<table>	+	</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 18:		Line 18:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Amrane, S.]]	+	[[Category: Amrane, S]]
-	[[Category: Mackereth, C D.]]	+	[[Category: Mackereth, C D]]
	[[Category: Development]]		[[Category: Development]]
	[[Category: Muscle]]		[[Category: Muscle]]
	[[Category: Rna binding protein-rna complex]]		[[Category: Rna binding protein-rna complex]]

OCA at 06:25, 24 September 2014

OCA — Wed, 24 Sep 2014 06:25:02 GMT

←Older revision		Revision as of 06:25, 24 September 2014
Line 6:		Line 6:
	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4cio FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4cio OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4cio RCSB], [http://www.ebi.ac.uk/pdbsum/4cio PDBsum]</span></td></tr>		<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4cio FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4cio OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4cio RCSB], [http://www.ebi.ac.uk/pdbsum/4cio PDBsum]</span></td></tr>
	<table>		<table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Cellular differentiation is frequently accompanied by alternative splicing, enabled by the expression of tissue-specific factors which bind to pre-mRNAs and regulate exon choice. During Caenorhabditis elegans development, muscle-specific expression of the splicing factor SUP-12, together with a member of the Fox-1 family of splicing proteins, generates a functionally distinct isoform of the fibroblast growth factor receptor EGL-15. Using a combination of NMR spectroscopy and isothermal titration calorimetry, we determined the mode of nucleic acid binding by the RNA recognition motif domain of SUP-12. The calculated structures provide the first atomic details of RNA and DNA binding by the family of proteins that include SUP-12, RBM24, RBM38/RNPC1, SEB-4 and XSeb4R. This information was further used to design strategic mutations to probe the interaction with ASD-1 and to quantitatively perturb splicing in vivo.
		+
		+	Backbone-independent nucleic acid binding by splicing factor SUP-12 reveals key aspects of molecular recognition.,Amrane S, Rebora K, Zniber I, Dupuy D, Mackereth CD Nat Commun. 2014 Sep 3;5:4595. doi: 10.1038/ncomms5595. PMID:25183497<ref>PMID:25183497</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>

OCA at 06:03, 4 September 2014

OCA — Thu, 04 Sep 2014 06:03:48 GMT

←Older revision		Revision as of 06:03, 4 September 2014
Line 1:		Line 1:
-	'''~~Unreleased structure~~'''	+	==RRM domain from C. elegans SUP-12 bound to GGUGUGC RNA==
-		+	<StructureSection load='4cio' size='340' side='right' caption='[[4cio]], [[NMR_Ensembles_of_Models \| 15 NMR models]]' scene=''>
-	~~The entry~~ 4cio is ~~ON HOLD until Paper Publication~~	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[4cio]] is a 2 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CIO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4CIO FirstGlance]. <br>
-	~~Authors~~: Amrane, S., Mackereth, C.D.	+	</td></tr><tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4ch0\|4ch0]], [[4ch1\|4ch1]]</td></tr>
-		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4cio FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4cio OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4cio RCSB], [http://www.ebi.ac.uk/pdbsum/4cio PDBsum]</span></td></tr>
-	~~Description~~: ~~RRM domain from C. elegans SUP~~-~~12 bound to GGUGUGC RNA~~	+	<table>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Amrane, S.]]
		+	[[Category: Mackereth, C D.]]
		+	[[Category: Development]]
		+	[[Category: Muscle]]
		+	[[Category: Rna binding protein-rna complex]]

OCA at 09:08, 25 December 2013

OCA — Wed, 25 Dec 2013 09:08:12 GMT

←Older revision		Revision as of 09:08, 25 December 2013
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 4cio is ON HOLD until ~~sometime in the future~~	+	The entry 4cio is ON HOLD until Paper Publication

	Authors: Amrane, S., Mackereth, C.D.		Authors: Amrane, S., Mackereth, C.D.

	Description: RRM domain from C. elegans SUP-12 bound to GGUGUGC RNA		Description: RRM domain from C. elegans SUP-12 bound to GGUGUGC RNA

OCA: Protected "4cio" [edit=sysop:move=sysop]

OCA — Wed, 18 Dec 2013 08:51:19 GMT

Protected "4cio" [edit=sysop:move=sysop]

←Older revision

Revision as of 08:51, 18 December 2013

OCA: New page: '''Unreleased structure''' The entry 4cio is ON HOLD until sometime in the future Authors: Amrane, S., Mackereth, C.D. Description: RRM domain from C. elegans SUP-12 bound to GGUGUGC R...

OCA — Wed, 18 Dec 2013 08:51:18 GMT

New page: '''Unreleased structure''' The entry 4cio is ON HOLD until sometime in the future Authors: Amrane, S., Mackereth, C.D. Description: RRM domain from C. elegans SUP-12 bound to GGUGUGC R...

New page

'''Unreleased structure'''

The entry 4cio is ON HOLD until sometime in the future

Authors: Amrane, S., Mackereth, C.D.

Description: RRM domain from C. elegans SUP-12 bound to GGUGUGC RNA