4cqh - Revision history

OCA at 12:14, 20 December 2023

OCA — Wed, 20 Dec 2023 12:14:50 GMT

←Older revision		Revision as of 12:14, 20 December 2023
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4cqh]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Deinococcus_radiodurans Deinococcus radiodurans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CQH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4CQH FirstGlance]. <br>		<table><tr><td colspan='2'>[[4cqh]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Deinococcus_radiodurans Deinococcus radiodurans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CQH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4CQH FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=LBV:3-[2-[(Z)-[3-(2-CARBOXYETHYL)-5-[(Z)-(4-ETHENYL-3-METHYL-5-OXIDANYLIDENE-PYRROL-2-YLIDENE)METHYL]-4-METHYL-PYRROL-1-IUM-2-YLIDENE]METHYL]-5-[(Z)-[(3E)-3-ETHYLIDENE-4-METHYL-5-OXIDANYLIDENE-PYRROLIDIN-2-YLIDENE]METHYL]-4-METHYL-1H-PYRROL-3-YL]PROPANOIC+ACID'>LBV</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.14Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=LBV:3-[2-[(Z)-[3-(2-CARBOXYETHYL)-5-[(Z)-(4-ETHENYL-3-METHYL-5-OXIDANYLIDENE-PYRROL-2-YLIDENE)METHYL]-4-METHYL-PYRROL-1-IUM-2-YLIDENE]METHYL]-5-[(Z)-[(3E)-3-ETHYLIDENE-4-METHYL-5-OXIDANYLIDENE-PYRROLIDIN-2-YLIDENE]METHYL]-4-METHYL-1H-PYRROL-3-YL]PROPANOIC+ACID'>LBV</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4cqh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4cqh OCA], [https://pdbe.org/4cqh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4cqh RCSB], [https://www.ebi.ac.uk/pdbsum/4cqh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4cqh ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4cqh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4cqh OCA], [https://pdbe.org/4cqh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4cqh RCSB], [https://www.ebi.ac.uk/pdbsum/4cqh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4cqh ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/BPHY_DEIRA BPHY_DEIRA]] Photoreceptor which exists in two forms that are reversibly interconvertible by light: the R form that absorbs maximally in the red region of the spectrum and the FR form that absorbs maximally in the far-red region. Has also a slight blue shift for the far-red maximum. Could also absorb green light. May participate in regulating pigment synthesis like the carotenoid deinoxanthin which could protect the bacterium from intense visible light.	+	[https://www.uniprot.org/uniprot/BPHY_DEIRA BPHY_DEIRA] Photoreceptor which exists in two forms that are reversibly interconvertible by light: the R form that absorbs maximally in the red region of the spectrum and the FR form that absorbs maximally in the far-red region. Has also a slight blue shift for the far-red maximum. Could also absorb green light. May participate in regulating pigment synthesis like the carotenoid deinoxanthin which could protect the bacterium from intense visible light.
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==

OCA at 07:27, 14 September 2022

OCA — Wed, 14 Sep 2022 07:27:32 GMT

←Older revision		Revision as of 07:27, 14 September 2022
Line 3:		Line 3:
	<StructureSection load='4cqh' size='340' side='right'caption='[[4cqh]], [[Resolution\|resolution]] 1.14Å' scene=''>		<StructureSection load='4cqh' size='340' side='right'caption='[[4cqh]], [[Resolution\|resolution]] 1.14Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4cqh]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~"micrococcus_radiodurans"_raj_et_al._1960 "micrococcus~~ radiodurans~~" raj et al. 1960~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CQH OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4CQH FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4cqh]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Deinococcus_radiodurans Deinococcus radiodurans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CQH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4CQH FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=LBV:3-[2-[(Z)-[3-(2-CARBOXYETHYL)-5-[(Z)-(4-ETHENYL-3-METHYL-5-OXIDANYLIDENE-PYRROL-2-YLIDENE)METHYL]-4-METHYL-PYRROL-1-IUM-2-YLIDENE]METHYL]-5-[(Z)-[(3E)-3-ETHYLIDENE-4-METHYL-5-OXIDANYLIDENE-PYRROLIDIN-2-YLIDENE]METHYL]-4-METHYL-1H-PYRROL-3-YL]PROPANOIC+ACID'>LBV</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=LBV:3-[2-[(Z)-[3-(2-CARBOXYETHYL)-5-[(Z)-(4-ETHENYL-3-METHYL-5-OXIDANYLIDENE-PYRROL-2-YLIDENE)METHYL]-4-METHYL-PYRROL-1-IUM-2-YLIDENE]METHYL]-5-[(Z)-[(3E)-3-ETHYLIDENE-4-METHYL-5-OXIDANYLIDENE-PYRROLIDIN-2-YLIDENE]METHYL]-4-METHYL-1H-PYRROL-3-YL]PROPANOIC+ACID'>LBV</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4cqh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4cqh OCA], [~~http~~://pdbe.org/4cqh PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4cqh RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4cqh PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4cqh ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4cqh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4cqh OCA], [https://pdbe.org/4cqh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4cqh RCSB], [https://www.ebi.ac.uk/pdbsum/4cqh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4cqh ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/BPHY_DEIRA BPHY_DEIRA]] Photoreceptor which exists in two forms that are reversibly interconvertible by light: the R form that absorbs maximally in the red region of the spectrum and the FR form that absorbs maximally in the far-red region. Has also a slight blue shift for the far-red maximum. Could also absorb green light. May participate in regulating pigment synthesis like the carotenoid deinoxanthin which could protect the bacterium from intense visible light.	+	[[https://www.uniprot.org/uniprot/BPHY_DEIRA BPHY_DEIRA]] Photoreceptor which exists in two forms that are reversibly interconvertible by light: the R form that absorbs maximally in the red region of the spectrum and the FR form that absorbs maximally in the far-red region. Has also a slight blue shift for the far-red maximum. Could also absorb green light. May participate in regulating pigment synthesis like the carotenoid deinoxanthin which could protect the bacterium from intense visible light.
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 22:		Line 22:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Micrococcus~~ radiodurans ~~raj et al. 1960~~]]	+	[[Category: Deinococcus radiodurans]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Lafaye, C]]	+	[[Category: Lafaye C]]
-	[[Category: Noirclerc-Savoye, M]]	+	[[Category: Noirclerc-Savoye M]]
-	[[Category: Royant, A]]	+	[[Category: Royant A]]
-	[[Category: Shu, X]]	+	[[Category: Shu X]]
-	[[Category: Yu, D]]	+	[[Category: Yu D]]
-	~~[[Category: Fluorescent protein]]~~	+
-	~~[[Category: Infrared fluorescent protein~~]]	+

OCA at 08:42, 20 March 2019

OCA — Wed, 20 Mar 2019 08:42:43 GMT

←Older revision		Revision as of 08:42, 20 March 2019
Line 1:		Line 1:

	==Structure of Infrared Fluorescent Protein IFP2.0==		==Structure of Infrared Fluorescent Protein IFP2.0==
-	<StructureSection load='4cqh' size='340' side='right' caption='[[4cqh]], [[Resolution\|resolution]] 1.14Å' scene=''>	+	<StructureSection load='4cqh' size='340' side='right'caption='[[4cqh]], [[Resolution\|resolution]] 1.14Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4cqh]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CQH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4CQH FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4cqh]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"micrococcus_radiodurans"_raj_et_al._1960 "micrococcus radiodurans" raj et al. 1960]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CQH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4CQH FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=LBV:3-[2-[(Z)-[3-(2-CARBOXYETHYL)-5-[(Z)-(4-ETHENYL-3-METHYL-5-OXIDANYLIDENE-PYRROL-2-YLIDENE)METHYL]-4-METHYL-PYRROL-1-IUM-2-YLIDENE]METHYL]-5-[(Z)-[(3E)-3-ETHYLIDENE-4-METHYL-5-OXIDANYLIDENE-PYRROLIDIN-2-YLIDENE]METHYL]-4-METHYL-1H-PYRROL-3-YL]PROPANOIC+ACID'>LBV</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=LBV:3-[2-[(Z)-[3-(2-CARBOXYETHYL)-5-[(Z)-(4-ETHENYL-3-METHYL-5-OXIDANYLIDENE-PYRROL-2-YLIDENE)METHYL]-4-METHYL-PYRROL-1-IUM-2-YLIDENE]METHYL]-5-[(Z)-[(3E)-3-ETHYLIDENE-4-METHYL-5-OXIDANYLIDENE-PYRROLIDIN-2-YLIDENE]METHYL]-4-METHYL-1H-PYRROL-3-YL]PROPANOIC+ACID'>LBV</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4cqh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4cqh OCA], [http://pdbe.org/4cqh PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4cqh RCSB], [http://www.ebi.ac.uk/pdbsum/4cqh PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4cqh ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4cqh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4cqh OCA], [http://pdbe.org/4cqh PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4cqh RCSB], [http://www.ebi.ac.uk/pdbsum/4cqh PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4cqh ProSAT]</span></td></tr>
Line 22:		Line 22:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Micrococcus radiodurans raj et al. 1960]]
		+	[[Category: Large Structures]]
	[[Category: Lafaye, C]]		[[Category: Lafaye, C]]
	[[Category: Noirclerc-Savoye, M]]		[[Category: Noirclerc-Savoye, M]]

OCA at 16:53, 5 August 2016

OCA — Fri, 05 Aug 2016 16:53:20 GMT

←Older revision		Revision as of 16:53, 5 August 2016
Line 1:		Line 1:
		+
	==Structure of Infrared Fluorescent Protein IFP2.0==		==Structure of Infrared Fluorescent Protein IFP2.0==
	<StructureSection load='4cqh' size='340' side='right' caption='[[4cqh]], [[Resolution\|resolution]] 1.14Å' scene=''>		<StructureSection load='4cqh' size='340' side='right' caption='[[4cqh]], [[Resolution\|resolution]] 1.14Å' scene=''>
Line 4:		Line 5:
	<table><tr><td colspan='2'>[[4cqh]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CQH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4CQH FirstGlance]. <br>		<table><tr><td colspan='2'>[[4cqh]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CQH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4CQH FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=LBV:3-[2-[(Z)-[3-(2-CARBOXYETHYL)-5-[(Z)-(4-ETHENYL-3-METHYL-5-OXIDANYLIDENE-PYRROL-2-YLIDENE)METHYL]-4-METHYL-PYRROL-1-IUM-2-YLIDENE]METHYL]-5-[(Z)-[(3E)-3-ETHYLIDENE-4-METHYL-5-OXIDANYLIDENE-PYRROLIDIN-2-YLIDENE]METHYL]-4-METHYL-1H-PYRROL-3-YL]PROPANOIC+ACID'>LBV</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=LBV:3-[2-[(Z)-[3-(2-CARBOXYETHYL)-5-[(Z)-(4-ETHENYL-3-METHYL-5-OXIDANYLIDENE-PYRROL-2-YLIDENE)METHYL]-4-METHYL-PYRROL-1-IUM-2-YLIDENE]METHYL]-5-[(Z)-[(3E)-3-ETHYLIDENE-4-METHYL-5-OXIDANYLIDENE-PYRROLIDIN-2-YLIDENE]METHYL]-4-METHYL-1H-PYRROL-3-YL]PROPANOIC+ACID'>LBV</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4cqh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4cqh OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4cqh RCSB], [http://www.ebi.ac.uk/pdbsum/4cqh PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4cqh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4cqh OCA], [http://pdbe.org/4cqh PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4cqh RCSB], [http://www.ebi.ac.uk/pdbsum/4cqh PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4cqh ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 16:		Line 17:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 4cqh" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 20:27, 25 December 2014

OCA — Thu, 25 Dec 2014 20:27:14 GMT

←Older revision		Revision as of 20:27, 25 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4cqh]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CQH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4CQH FirstGlance]. <br>		<table><tr><td colspan='2'>[[4cqh]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CQH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4CQH FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=LBV:3-[2-[(Z)-[3-(2-CARBOXYETHYL)-5-[(Z)-(4-ETHENYL-3-METHYL-5-OXIDANYLIDENE-PYRROL-2-YLIDENE)METHYL]-4-METHYL-PYRROL-1-IUM-2-YLIDENE]METHYL]-5-[(Z)-[(3E)-3-ETHYLIDENE-4-METHYL-5-OXIDANYLIDENE-PYRROLIDIN-2-YLIDENE]METHYL]-4-METHYL-1H-PYRROL-3-YL]PROPANOIC+ACID'>LBV</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=LBV:3-[2-[(Z)-[3-(2-CARBOXYETHYL)-5-[(Z)-(4-ETHENYL-3-METHYL-5-OXIDANYLIDENE-PYRROL-2-YLIDENE)METHYL]-4-METHYL-PYRROL-1-IUM-2-YLIDENE]METHYL]-5-[(Z)-[(3E)-3-ETHYLIDENE-4-METHYL-5-OXIDANYLIDENE-PYRROLIDIN-2-YLIDENE]METHYL]-4-METHYL-1H-PYRROL-3-YL]PROPANOIC+ACID'>LBV</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4cqh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4cqh OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4cqh RCSB], [http://www.ebi.ac.uk/pdbsum/4cqh PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4cqh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4cqh OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4cqh RCSB], [http://www.ebi.ac.uk/pdbsum/4cqh PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/BPHY_DEIRA BPHY_DEIRA]] Photoreceptor which exists in two forms that are reversibly interconvertible by light: the R form that absorbs maximally in the red region of the spectrum and the FR form that absorbs maximally in the far-red region. Has also a slight blue shift for the far-red maximum. Could also absorb green light. May participate in regulating pigment synthesis like the carotenoid deinoxanthin which could protect the bacterium from intense visible light.
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 12:		Line 14:
	An improved monomeric infrared fluorescent protein for neuronal and tumour brain imaging.,Yu D, Gustafson WC, Han C, Lafaye C, Noirclerc-Savoye M, Ge WP, Thayer DA, Huang H, Kornberg TB, Royant A, Jan LY, Jan YN, Weiss WA, Shu X Nat Commun. 2014 May 15;5:3626. doi: 10.1038/ncomms4626. PMID:24832154<ref>PMID:24832154</ref>		An improved monomeric infrared fluorescent protein for neuronal and tumour brain imaging.,Yu D, Gustafson WC, Han C, Lafaye C, Noirclerc-Savoye M, Ge WP, Thayer DA, Huang H, Kornberg TB, Royant A, Jan LY, Jan YN, Weiss WA, Shu X Nat Commun. 2014 May 15;5:3626. doi: 10.1038/ncomms4626. PMID:24832154<ref>PMID:24832154</ref>

-	From ~~MEDLINEÂ®~~/~~PubMedÂ®~~, a database of the U.S. National Library of Medicine.<br>	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
	== References ==		== References ==
Line 18:		Line 20:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Lafaye, C.]]	+	[[Category: Lafaye, C]]
-	[[Category: Noirclerc-Savoye, M.]]	+	[[Category: Noirclerc-Savoye, M]]
-	[[Category: Royant, A.]]	+	[[Category: Royant, A]]
-	[[Category: Shu, X.]]	+	[[Category: Shu, X]]
-	[[Category: Yu, D.]]	+	[[Category: Yu, D]]
	[[Category: Fluorescent protein]]		[[Category: Fluorescent protein]]
	[[Category: Infrared fluorescent protein]]		[[Category: Infrared fluorescent protein]]

OCA at 09:34, 28 May 2014

OCA — Wed, 28 May 2014 09:34:05 GMT

←Older revision		Revision as of 09:34, 28 May 2014
Line 1:		Line 1:
-	'''~~Unreleased~~ structure'''	+	==Structure of Infrared Fluorescent Protein IFP2.0==
		+	<StructureSection load='4cqh' size='340' side='right' caption='[[4cqh]], [[Resolution\|resolution]] 1.14Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[4cqh]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CQH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4CQH FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=LBV:3-[2-[(Z)-[3-(2-CARBOXYETHYL)-5-[(Z)-(4-ETHENYL-3-METHYL-5-OXIDANYLIDENE-PYRROL-2-YLIDENE)METHYL]-4-METHYL-PYRROL-1-IUM-2-YLIDENE]METHYL]-5-[(Z)-[(3E)-3-ETHYLIDENE-4-METHYL-5-OXIDANYLIDENE-PYRROLIDIN-2-YLIDENE]METHYL]-4-METHYL-1H-PYRROL-3-YL]PROPANOIC+ACID'>LBV</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene><br>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4cqh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4cqh OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4cqh RCSB], [http://www.ebi.ac.uk/pdbsum/4cqh PDBsum]</span></td></tr>
		+	<table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Infrared fluorescent proteins (IFPs) are ideal for in vivo imaging, and monomeric versions of these proteins can be advantageous as protein tags or for sensor development. In contrast to GFP, which requires only molecular oxygen for chromophore maturation, phytochrome-derived IFPs incorporate biliverdin (BV) as the chromophore. However, BV varies in concentration in different cells and organisms. Here we engineered cells to express the haeme oxygenase responsible for BV biosynthesis and a brighter monomeric IFP mutant (IFP2.0). Together, these tools improve the imaging capabilities of IFP2.0 compared with monomeric IFP1.4 and dimeric iRFP. By targeting IFP2.0 to the plasma membrane, we demonstrate robust labelling of neuronal processes in Drosophila larvae. We also show that this strategy improves the sensitivity when imaging brain tumours in whole mice. Our work shows promise in the application of IFPs for protein labelling and in vivo imaging.

-	~~The entry 4cqh is ON HOLD until Paper Publication~~	+	An improved monomeric infrared fluorescent protein for neuronal and tumour brain imaging.,Yu D, Gustafson WC, Han C, Lafaye C, Noirclerc-Savoye M, Ge WP, Thayer DA, Huang H, Kornberg TB, Royant A, Jan LY, Jan YN, Weiss WA, Shu X Nat Commun. 2014 May 15;5:3626. doi: 10.1038/ncomms4626. PMID:24832154<ref>PMID:24832154</ref>

-	~~Authors~~: Lafaye, C.~~, Yu, D.,~~ Noirclerc-Savoye, M., Shu, X., ~~Royant, A~~.	+	From MEDLINEÂ®/PubMedÂ®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~Description~~: ~~Structure of~~ Infrared ~~Fluorescent Protein IFP2.0~~	+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Lafaye, C.]]
		+	[[Category: Noirclerc-Savoye, M.]]
		+	[[Category: Royant, A.]]
		+	[[Category: Shu, X.]]
		+	[[Category: Yu, D.]]
		+	[[Category: Fluorescent protein]]
		+	[[Category: Infrared fluorescent protein]]

OCA at 08:26, 26 March 2014

OCA — Wed, 26 Mar 2014 08:26:15 GMT

←Older revision		Revision as of 08:26, 26 March 2014
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 4cqh is ON HOLD	+	The entry 4cqh is ON HOLD until Paper Publication

	Authors: Lafaye, C., Yu, D., Noirclerc-Savoye, M., Shu, X., Royant, A.		Authors: Lafaye, C., Yu, D., Noirclerc-Savoye, M., Shu, X., Royant, A.

	Description: Structure of Infrared Fluorescent Protein IFP2.0		Description: Structure of Infrared Fluorescent Protein IFP2.0

OCA: Protected "4cqh" [edit=sysop:move=sysop]

OCA — Mon, 03 Mar 2014 16:17:26 GMT

Protected "4cqh" [edit=sysop:move=sysop]

←Older revision

Revision as of 16:17, 3 March 2014

OCA: New page: '''Unreleased structure''' The entry 4cqh is ON HOLD Authors: Lafaye, C., Yu, D., Noirclerc-Savoye, M., Shu, X., Royant, A. Description: Structure of Infrared Fluorescent Protein IFP2....

OCA — Mon, 03 Mar 2014 16:17:25 GMT

New page: '''Unreleased structure''' The entry 4cqh is ON HOLD Authors: Lafaye, C., Yu, D., Noirclerc-Savoye, M., Shu, X., Royant, A. Description: Structure of Infrared Fluorescent Protein IFP2....

New page

'''Unreleased structure'''

The entry 4cqh is ON HOLD

Authors: Lafaye, C., Yu, D., Noirclerc-Savoye, M., Shu, X., Royant, A.

Description: Structure of Infrared Fluorescent Protein IFP2.0