4d2c - Revision history

OCA at 12:19, 20 December 2023

OCA — Wed, 20 Dec 2023 12:19:42 GMT

←Older revision		Revision as of 12:19, 20 December 2023
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4d2c]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptococcus_thermophilus_LMG_18311 Streptococcus thermophilus LMG 18311]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4D2C OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4D2C FirstGlance]. <br>		<table><tr><td colspan='2'>[[4d2c]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptococcus_thermophilus_LMG_18311 Streptococcus thermophilus LMG 18311]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4D2C OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4D2C FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=78M:(2S)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE'>78M</scene>, <scene name='pdbligand=78N:(2R)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE'>78N</scene>, <scene name='pdbligand=ALA:ALANINE'>ALA</scene>, <scene name='pdbligand=PHE:PHENYLALANINE'>PHE</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.47Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=78M:(2S)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE'>78M</scene>, <scene name='pdbligand=78N:(2R)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE'>78N</scene>, <scene name='pdbligand=ALA:ALANINE'>ALA</scene>, <scene name='pdbligand=PHE:PHENYLALANINE'>PHE</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4d2c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4d2c OCA], [https://pdbe.org/4d2c PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4d2c RCSB], [https://www.ebi.ac.uk/pdbsum/4d2c PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4d2c ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4d2c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4d2c OCA], [https://pdbe.org/4d2c PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4d2c RCSB], [https://www.ebi.ac.uk/pdbsum/4d2c PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4d2c ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/Q5M4H8_STRT2 Q5M4H8_STRT2]]	+	[https://www.uniprot.org/uniprot/Q5M4H8_STRT2 Q5M4H8_STRT2]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==

OCA at 07:43, 14 September 2022

OCA — Wed, 14 Sep 2022 07:43:48 GMT

←Older revision		Revision as of 07:43, 14 September 2022
Line 1:		Line 1:

	==Structure of a di peptide bound POT family peptide transporter==		==Structure of a di peptide bound POT family peptide transporter==
-	<StructureSection load='4d2c' size='340' side='right' caption='[[4d2c]], [[Resolution\|resolution]] 2.47Å' scene=''>	+	<StructureSection load='4d2c' size='340' side='right'caption='[[4d2c]], [[Resolution\|resolution]] 2.47Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4d2c]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Strt2 Strt2~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4D2C OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4D2C FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4d2c]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptococcus_thermophilus_LMG_18311 Streptococcus thermophilus LMG 18311]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4D2C OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4D2C FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=78M:(2S)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE'>78M</scene>, <scene name='pdbligand=78N:(2R)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE'>78N</scene>, <scene name='pdbligand=ALA:ALANINE'>ALA</scene>, <scene name='pdbligand=PHE:PHENYLALANINE'>PHE</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>~~</td></tr>~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=78M:(2S)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE'>78M</scene>, <scene name='pdbligand=78N:(2R)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE'>78N</scene>, <scene name='pdbligand=ALA:ALANINE'>ALA</scene>, <scene name='pdbligand=PHE:PHENYLALANINE'>PHE</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4d2b\|4d2b]], [[4d2d\|4d2d]]</td></tr>~~	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4d2c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4d2c OCA], [https://pdbe.org/4d2c PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4d2c RCSB], [https://www.ebi.ac.uk/pdbsum/4d2c PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4d2c ProSAT]</span></td></tr>
-	~~<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">dtpT, stu0970 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=264199 STRT2])~~</td></tr>	+
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4d2c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4d2c OCA], [~~http~~://pdbe.org/4d2c PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4d2c RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4d2c PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4d2c ProSAT]</span></td></tr>	+
	</table>		</table>
		+	== Function ==
		+	[[https://www.uniprot.org/uniprot/Q5M4H8_STRT2 Q5M4H8_STRT2]]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 18:		Line 18:
	</div>		</div>
	<div class="pdbe-citations 4d2c" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 4d2c" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Symporter\|Symporter]]
		+	*[[Symporter 3D structures\|Symporter 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Strt2~~]]	+	[[Category: Large Structures]]
-	[[Category: Brinth, A]]	+	[[Category: Streptococcus thermophilus LMG 18311]]
-	[[Category: Caffrey, M]]	+	[[Category: Brinth A]]
-	[[Category: Li, D]]	+	[[Category: Caffrey M]]
-	[[Category: Lyons~~, J A~~]]	+	[[Category: Li D]]
-	[[Category: Newstead, S]]	+	[[Category: Lyons JA]]
-	[[Category: Parker~~, J L~~]]	+	[[Category: Newstead S]]
-	[[Category: Shah~~, S T.A~~]]	+	[[Category: Parker JL]]
-	[[Category: Solcan, N]]	+	[[Category: Shah STA]]
-	~~[[Category: Major facilitator superfamily]]~~	+	[[Category: Solcan N]]
-	~~[[Category: Peptide complex]]~~	+
-	~~[[Category: Peptide transporter]]~~	+
-	~~[[Category: Transport protein~~]]	+

OCA at 07:37, 22 February 2018

OCA — Thu, 22 Feb 2018 07:37:57 GMT

←Older revision		Revision as of 07:37, 22 February 2018
Line 3:		Line 3:
	<StructureSection load='4d2c' size='340' side='right' caption='[[4d2c]], [[Resolution\|resolution]] 2.47Å' scene=''>		<StructureSection load='4d2c' size='340' side='right' caption='[[4d2c]], [[Resolution\|resolution]] 2.47Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4d2c]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4D2C OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4D2C FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4d2c]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Strt2 Strt2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4D2C OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4D2C FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=78M:(2S)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE'>78M</scene>, <scene name='pdbligand=78N:(2R)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE'>78N</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=78M:(2S)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE'>78M</scene>, <scene name='pdbligand=78N:(2R)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE'>78N</scene>, <scene name='pdbligand=ALA:ALANINE'>ALA</scene>, <scene name='pdbligand=PHE:PHENYLALANINE'>PHE</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4d2b\|4d2b]], [[4d2d\|4d2d]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4d2b\|4d2b]], [[4d2d\|4d2d]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">dtpT, stu0970 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=264199 STRT2])</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4d2c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4d2c OCA], [http://pdbe.org/4d2c PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4d2c RCSB], [http://www.ebi.ac.uk/pdbsum/4d2c PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4d2c ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4d2c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4d2c OCA], [http://pdbe.org/4d2c PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4d2c RCSB], [http://www.ebi.ac.uk/pdbsum/4d2c PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4d2c ProSAT]</span></td></tr>
	</table>		</table>
Line 17:		Line 18:
	</div>		</div>
	<div class="pdbe-citations 4d2c" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 4d2c" style="background-color:#fffaf0;"></div>
-
-	==See Also==
-	*[[Symporter\|Symporter]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Strt2]]
	[[Category: Brinth, A]]		[[Category: Brinth, A]]
	[[Category: Caffrey, M]]		[[Category: Caffrey, M]]

OCA at 18:17, 11 August 2016

OCA — Thu, 11 Aug 2016 18:17:52 GMT

←Older revision		Revision as of 18:17, 11 August 2016
Line 1:		Line 1:
		+
	==Structure of a di peptide bound POT family peptide transporter==		==Structure of a di peptide bound POT family peptide transporter==
	<StructureSection load='4d2c' size='340' side='right' caption='[[4d2c]], [[Resolution\|resolution]] 2.47Å' scene=''>		<StructureSection load='4d2c' size='340' side='right' caption='[[4d2c]], [[Resolution\|resolution]] 2.47Å' scene=''>
Line 5:		Line 6:
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=78M:(2S)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE'>78M</scene>, <scene name='pdbligand=78N:(2R)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE'>78N</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=78M:(2S)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE'>78M</scene>, <scene name='pdbligand=78N:(2R)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE'>78N</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4d2b\|4d2b]], [[4d2d\|4d2d]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4d2b\|4d2b]], [[4d2d\|4d2d]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4d2c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4d2c OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4d2c RCSB], [http://www.ebi.ac.uk/pdbsum/4d2c PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4d2c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4d2c OCA], [http://pdbe.org/4d2c PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4d2c RCSB], [http://www.ebi.ac.uk/pdbsum/4d2c PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4d2c ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 15:		Line 16:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 4d2c" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Symporter\|Symporter]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 14:47, 5 January 2015

OCA — Mon, 05 Jan 2015 14:47:33 GMT

←Older revision		Revision as of 14:47, 5 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4d2c]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4D2C OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4D2C FirstGlance]. <br>		<table><tr><td colspan='2'>[[4d2c]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4D2C OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4D2C FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=78M:(2S)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE'>78M</scene>, <scene name='pdbligand=78N:(2R)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE'>78N</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=78M:(2S)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE'>78M</scene>, <scene name='pdbligand=78N:(2R)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE'>78N</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4d2b\|4d2b]], [[4d2d\|4d2d]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4d2b\|4d2b]], [[4d2d\|4d2d]]</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4d2c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4d2c OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4d2c RCSB], [http://www.ebi.ac.uk/pdbsum/4d2c PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4d2c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4d2c OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4d2c RCSB], [http://www.ebi.ac.uk/pdbsum/4d2c PDBsum]</span></td></tr>
-	<table>	+	</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 19:		Line 19:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Brinth, A.]]	+	[[Category: Brinth, A]]
-	[[Category: Caffrey, M.]]	+	[[Category: Caffrey, M]]
-	[[Category: Li, D.]]	+	[[Category: Li, D]]
-	[[Category: Lyons, J A.]]	+	[[Category: Lyons, J A]]
-	[[Category: Newstead, S.]]	+	[[Category: Newstead, S]]
-	[[Category: Parker, J L.]]	+	[[Category: Parker, J L]]
-	[[Category: Shah, S T.A.]]	+	[[Category: Shah, S T.A]]
-	[[Category: Solcan, N.]]	+	[[Category: Solcan, N]]
	[[Category: Major facilitator superfamily]]		[[Category: Major facilitator superfamily]]
	[[Category: Peptide complex]]		[[Category: Peptide complex]]
	[[Category: Peptide transporter]]		[[Category: Peptide transporter]]
	[[Category: Transport protein]]		[[Category: Transport protein]]

OCA at 06:27, 25 June 2014

OCA — Wed, 25 Jun 2014 06:27:42 GMT

←Older revision		Revision as of 06:27, 25 June 2014
Line 1:		Line 1:
-	'''~~Unreleased~~ structure'''	+	==Structure of a di peptide bound POT family peptide transporter==
		+	<StructureSection load='4d2c' size='340' side='right' caption='[[4d2c]], [[Resolution\|resolution]] 2.47Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[4d2c]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4D2C OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4D2C FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=78M:(2S)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE'>78M</scene>, <scene name='pdbligand=78N:(2R)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE'>78N</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4d2b\|4d2b]], [[4d2d\|4d2d]]</td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4d2c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4d2c OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4d2c RCSB], [http://www.ebi.ac.uk/pdbsum/4d2c PDBsum]</span></td></tr>
		+	<table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	An enigma in the field of peptide transport is the structural basis for ligand promiscuity, as exemplified by PepT1, the mammalian plasma membrane peptide transporter. Here, we present crystal structures of di- and tripeptide-bound complexes of a bacterial homologue of PepT1, which reveal at least two mechanisms for peptide recognition that operate within a single, centrally located binding site. The dipeptide was orientated laterally in the binding site, whereas the tripeptide revealed an alternative vertical binding mode. The co-crystal structures combined with functional studies reveal that biochemically distinct peptide-binding sites likely operate within the POT/PTR family of proton-coupled symporters and suggest that transport promiscuity has arisen in part through the ability of the binding site to accommodate peptides in multiple orientations for transport.

-	~~The entry 4d2c is ON HOLD until Paper Publication~~	+	Structural basis for polyspecificity in the POT family of proton-coupled oligopeptide transporters.,Lyons JA, Parker JL, Solcan N, Brinth A, Li D, Shah ST, Caffrey M, Newstead S EMBO Rep. 2014 Jun 10. pii: e201338403. PMID:24916388<ref>PMID:24916388</ref>

-	~~Authors: Lyons~~, J.A.~~, Parker, J.L~~.~~, Solcan, N.,~~ Brinth, A., Li, D., ~~Shah~~, S.T.A., ~~Caffrey, M., Newstead, S~~.	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~Description~~: ~~Structure of a di peptide bound POT family peptide~~ transporter	+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Brinth, A.]]
		+	[[Category: Caffrey, M.]]
		+	[[Category: Li, D.]]
		+	[[Category: Lyons, J A.]]
		+	[[Category: Newstead, S.]]
		+	[[Category: Parker, J L.]]
		+	[[Category: Shah, S T.A.]]
		+	[[Category: Solcan, N.]]
		+	[[Category: Major facilitator superfamily]]
		+	[[Category: Peptide complex]]
		+	[[Category: Peptide transporter]]
		+	[[Category: Transport protein]]

OCA at 07:32, 21 May 2014

OCA — Wed, 21 May 2014 07:32:30 GMT

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	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 4d2c is ON HOLD	+	The entry 4d2c is ON HOLD until Paper Publication

	Authors: Lyons, J.A., Parker, J.L., Solcan, N., Brinth, A., Li, D., Shah, S.T.A., Caffrey, M., Newstead, S.		Authors: Lyons, J.A., Parker, J.L., Solcan, N., Brinth, A., Li, D., Shah, S.T.A., Caffrey, M., Newstead, S.

	Description: Structure of a di peptide bound POT family peptide transporter		Description: Structure of a di peptide bound POT family peptide transporter

OCA: Protected "4d2c" [edit=sysop:move=sysop]

OCA — Wed, 14 May 2014 07:02:54 GMT

Protected "4d2c" [edit=sysop:move=sysop]

←Older revision

Revision as of 07:02, 14 May 2014

OCA: New page: '''Unreleased structure''' The entry 4d2c is ON HOLD Authors: Lyons, J.A., Parker, J.L., Solcan, N., Brinth, A., Li, D., Shah, S.T.A., Caffrey, M., Newstead, S. Description: Structure ...

OCA — Wed, 14 May 2014 07:02:54 GMT

New page: '''Unreleased structure''' The entry 4d2c is ON HOLD Authors: Lyons, J.A., Parker, J.L., Solcan, N., Brinth, A., Li, D., Shah, S.T.A., Caffrey, M., Newstead, S. Description: Structure ...

New page

'''Unreleased structure'''

The entry 4d2c is ON HOLD

Authors: Lyons, J.A., Parker, J.L., Solcan, N., Brinth, A., Li, D., Shah, S.T.A., Caffrey, M., Newstead, S.

Description: Structure of a di peptide bound POT family peptide transporter