4dhu - Revision history

OCA at 08:18, 21 September 2022

OCA — Wed, 21 Sep 2022 08:18:59 GMT

←Older revision		Revision as of 08:18, 21 September 2022
Line 1:		Line 1:

	==Small-molecule inhibitors of 14-3-3 protein-protein interactions from virtual screening==		==Small-molecule inhibitors of 14-3-3 protein-protein interactions from virtual screening==
-	<StructureSection load='4dhu' size='340' side='right' caption='[[4dhu]], [[Resolution\|resolution]] 1.67Å' scene=''>	+	<StructureSection load='4dhu' size='340' side='right'caption='[[4dhu]], [[Resolution\|resolution]] 1.67Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4dhu]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Human Human~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DHU OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4DHU FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4dhu]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DHU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4DHU FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=0KH:(2-{2-[(2,3-DICHLOROPHENYL)AMINO]-2-OXOETHOXY}PHENYL)PHOSPHONIC+ACID'>0KH</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=~~GOL~~:~~GLYCEROL~~'>~~GOL~~</scene>, <scene name='pdbligand=MG:~~MAGNESIUM+ION~~'>MG</scene>~~</td></tr>~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=0KH:(2-{2-[(2,3-DICHLOROPHENYL)AMINO]-2-OXOETHOXY}PHENYL)PHOSPHONIC+ACID'>0KH</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-	~~<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat">~~<scene name='pdbligand=~~CSO~~:~~S-HYDROXYCYSTEINE~~'>~~CSO~~</scene>~~</td></tr>~~	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4dhu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4dhu OCA], [https://pdbe.org/4dhu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4dhu RCSB], [https://www.ebi.ac.uk/pdbsum/4dhu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4dhu ProSAT]</span></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3t0l\|3t0l]], [[3t0m\|3t0m]], [[3u9x\|3u9x]], [[4dhm\|4dhm]], [[4dhn\|4dhn]], [[4dho\|4dho]], [[4dhp\|4dhp]], [[4dhq\|4dhq]], [[4dhr\|4dhr]], [[4dhs\|4dhs]], [[4dht\|4dht]]</td></tr>	+
-	~~<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">HME1, SFN ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])~~</td></tr>	+
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4dhu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4dhu OCA], [~~http~~://pdbe.org/4dhu PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4dhu RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4dhu PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4dhu ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/1433S_HUMAN 1433S_HUMAN]] Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. When bound to KRT17, regulates protein synthesis and epithelial cell growth by stimulating Akt/mTOR pathway (By similarity). p53-regulated inhibitor of G2/M progression.	+	[[https://www.uniprot.org/uniprot/1433S_HUMAN 1433S_HUMAN]] Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. When bound to KRT17, regulates protein synthesis and epithelial cell growth by stimulating Akt/mTOR pathway (By similarity). p53-regulated inhibitor of G2/M progression.
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 23:		Line 20:

	==See Also==		==See Also==
-	*[[14-3-3 protein\|14-3-3 protein]]	+	*[[14-3-3 protein 3D structures\|14-3-3 protein 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Human~~]]	+	[[Category: Homo sapiens]]
-	[[Category: Kohlbacher, O]]	+	[[Category: Large Structures]]
-	[[Category: Ottmann, C]]	+	[[Category: Kohlbacher O]]
-	[[Category: Roeglin, L]]	+	[[Category: Ottmann C]]
-	[[Category: Thiel, P]]	+	[[Category: Roeglin L]]
-	~~[[Category: Adapter protein]]~~	+	[[Category: Thiel P]]
-	~~[[Category: Helical protein]]~~	+
-	~~[[Category: Phosphoprotein binding]]~~	+
-	~~[[Category: Protein binding-inhibitor complex~~]]	+

OCA at 19:27, 5 August 2016

OCA — Fri, 05 Aug 2016 19:27:27 GMT

←Older revision		Revision as of 19:27, 5 August 2016
Line 1:		Line 1:
		+
	==Small-molecule inhibitors of 14-3-3 protein-protein interactions from virtual screening==		==Small-molecule inhibitors of 14-3-3 protein-protein interactions from virtual screening==
	<StructureSection load='4dhu' size='340' side='right' caption='[[4dhu]], [[Resolution\|resolution]] 1.67Å' scene=''>		<StructureSection load='4dhu' size='340' side='right' caption='[[4dhu]], [[Resolution\|resolution]] 1.67Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4dhu]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Homo_sapiens Homo sapiens~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DHU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4DHU FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4dhu]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DHU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4DHU FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=0KH:(2-{2-[(2,3-DICHLOROPHENYL)AMINO]-2-OXOETHOXY}PHENYL)PHOSPHONIC+ACID'>0KH</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=0KH:(2-{2-[(2,3-DICHLOROPHENYL)AMINO]-2-OXOETHOXY}PHENYL)PHOSPHONIC+ACID'>0KH</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3t0l\|3t0l]], [[3t0m\|3t0m]], [[3u9x\|3u9x]], [[4dhm\|4dhm]], [[4dhn\|4dhn]], [[4dho\|4dho]], [[4dhp\|4dhp]], [[4dhq\|4dhq]], [[4dhr\|4dhr]], [[4dhs\|4dhs]], [[4dht\|4dht]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3t0l\|3t0l]], [[3t0m\|3t0m]], [[3u9x\|3u9x]], [[4dhm\|4dhm]], [[4dhn\|4dhn]], [[4dho\|4dho]], [[4dhp\|4dhp]], [[4dhq\|4dhq]], [[4dhr\|4dhr]], [[4dhs\|4dhs]], [[4dht\|4dht]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">HME1, SFN ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 ~~Homo sapiens~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">HME1, SFN ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4dhu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4dhu OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4dhu RCSB], [http://www.ebi.ac.uk/pdbsum/4dhu PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4dhu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4dhu OCA], [http://pdbe.org/4dhu PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4dhu RCSB], [http://www.ebi.ac.uk/pdbsum/4dhu PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4dhu ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 19:		Line 20:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 4dhu" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 26:		Line 28:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Homo sapiens~~]]	+	[[Category: Human]]
	[[Category: Kohlbacher, O]]		[[Category: Kohlbacher, O]]
	[[Category: Ottmann, C]]		[[Category: Ottmann, C]]

OCA at 05:12, 25 December 2014

OCA — Thu, 25 Dec 2014 05:12:50 GMT

←Older revision		Revision as of 05:12, 25 December 2014
Line 1:		Line 1:
-	~~{{STRUCTURE_4dhu\| PDB=4dhu \| SCENE= }}~~	+	==Small-molecule inhibitors of 14-3-3 protein-protein interactions from virtual screening==
-	===Small-molecule inhibitors of 14-3-3 protein-protein interactions from virtual screening===	+	<StructureSection load='4dhu' size='340' side='right' caption='[[4dhu]], [[Resolution\|resolution]] 1.67Å' scene=''>
-	{~~{ABSTRACT_PUBMED_23939230}~~}	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[4dhu]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DHU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4DHU FirstGlance]. <br>
-	==Function==	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=0KH:(2-{2-[(2,3-DICHLOROPHENYL)AMINO]-2-OXOETHOXY}PHENYL)PHOSPHONIC+ACID'>0KH</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
		+	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3t0l\|3t0l]], [[3t0m\|3t0m]], [[3u9x\|3u9x]], [[4dhm\|4dhm]], [[4dhn\|4dhn]], [[4dho\|4dho]], [[4dhp\|4dhp]], [[4dhq\|4dhq]], [[4dhr\|4dhr]], [[4dhs\|4dhs]], [[4dht\|4dht]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">HME1, SFN ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4dhu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4dhu OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4dhu RCSB], [http://www.ebi.ac.uk/pdbsum/4dhu PDBsum]</span></td></tr>
		+	</table>
		+	== Function ==
	[[http://www.uniprot.org/uniprot/1433S_HUMAN 1433S_HUMAN]] Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. When bound to KRT17, regulates protein synthesis and epithelial cell growth by stimulating Akt/mTOR pathway (By similarity). p53-regulated inhibitor of G2/M progression.		[[http://www.uniprot.org/uniprot/1433S_HUMAN 1433S_HUMAN]] Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. When bound to KRT17, regulates protein synthesis and epithelial cell growth by stimulating Akt/mTOR pathway (By similarity). p53-regulated inhibitor of G2/M progression.
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	We report first non-covalent and exclusively extracellular inhibitors of 14-3-3 protein-protein interactions identified by virtual screening. Optimization by crystal structure analysis and in vitro binding assays yielded compounds capable of disrupting the interaction of 14-3-3sigma with aminopeptidase N in a cellular assay.
		+
		+	Virtual screening and experimental validation reveal novel small-molecule inhibitors of 14-3-3 protein-protein interactions.,Thiel P, Roglin L, Meissner N, Hennig S, Kohlbacher O, Ottmann C Chem Commun (Camb). 2013 Aug 27;49(76):8468-70. doi: 10.1039/c3cc44612c. PMID:23939230<ref>PMID:23939230</ref>

-	~~==About this Structure==~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	~~[[4dhu]] is~~ a ~~1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Homo_sapiens Homo sapiens]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=4DHU OCA].~~	+	</div>

-	==~~Reference~~==	+	==See Also==
-	~~<ref group~~=~~"xtra">PMID:023939230</ref>~~<references ~~group="xtra"~~/><~~references~~/>	+	*[[14-3-3 protein\|14-3-3 protein]]
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
	[[Category: Homo sapiens]]		[[Category: Homo sapiens]]
-	[[Category: Kohlbacher, O.]]	+	[[Category: Kohlbacher, O]]
-	[[Category: Ottmann, C.]]	+	[[Category: Ottmann, C]]
-	[[Category: Roeglin, L.]]	+	[[Category: Roeglin, L]]
-	[[Category: Thiel, P.]]	+	[[Category: Thiel, P]]
	[[Category: Adapter protein]]		[[Category: Adapter protein]]
	[[Category: Helical protein]]		[[Category: Helical protein]]
	[[Category: Phosphoprotein binding]]		[[Category: Phosphoprotein binding]]
	[[Category: Protein binding-inhibitor complex]]		[[Category: Protein binding-inhibitor complex]]

OCA at 09:14, 4 September 2013

OCA — Wed, 04 Sep 2013 09:14:00 GMT

←Older revision		Revision as of 09:14, 4 September 2013
Line 1:		Line 1:
	{{STRUCTURE_4dhu\| PDB=4dhu \| SCENE= }}		{{STRUCTURE_4dhu\| PDB=4dhu \| SCENE= }}
	===Small-molecule inhibitors of 14-3-3 protein-protein interactions from virtual screening===		===Small-molecule inhibitors of 14-3-3 protein-protein interactions from virtual screening===
		+	{{ABSTRACT_PUBMED_23939230}}

	==Function==		==Function==
Line 7:		Line 8:
	==About this Structure==		==About this Structure==
	[[4dhu]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DHU OCA].		[[4dhu]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DHU OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:023939230</ref><references group="xtra"/><references/>
	[[Category: Homo sapiens]]		[[Category: Homo sapiens]]
	[[Category: Kohlbacher, O.]]		[[Category: Kohlbacher, O.]]

OCA at 05:15, 1 August 2013

OCA — Thu, 01 Aug 2013 05:15:15 GMT

←Older revision		Revision as of 05:15, 1 August 2013
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	{{STRUCTURE_4dhu\| PDB=4dhu \| SCENE= }}
		+	===Small-molecule inhibitors of 14-3-3 protein-protein interactions from virtual screening===

-	~~The entry 4dhu is ON HOLD~~ ~~until Jul 31 2014~~	+	==Function==
		+	[[http://www.uniprot.org/uniprot/1433S_HUMAN 1433S_HUMAN]] Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. When bound to KRT17, regulates protein synthesis and epithelial cell growth by stimulating Akt/mTOR pathway (By similarity). p53-regulated inhibitor of G2/M progression.

-	~~Authors~~: ~~Thiel, P~~.~~, Roeglin, L~~., Kohlbacher, O., Ottmann, C.	+	==About this Structure==
-		+	[[4dhu]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DHU OCA].
-	~~Description~~: ~~Small-molecule inhibitors of 14-3-3~~ protein-protein ~~interactions from virtual screening~~	+	[[Category: Homo sapiens]]
		+	[[Category: Kohlbacher, O.]]
		+	[[Category: Ottmann, C.]]
		+	[[Category: Roeglin, L.]]
		+	[[Category: Thiel, P.]]
		+	[[Category: Adapter protein]]
		+	[[Category: Helical protein]]
		+	[[Category: Phosphoprotein binding]]
		+	[[Category: Protein binding-inhibitor complex]]

OCA at 14:09, 27 February 2013

OCA — Wed, 27 Feb 2013 14:09:25 GMT

←Older revision		Revision as of 14:09, 27 February 2013
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 4dhu is ON HOLD until ~~Paper Publication~~	+	The entry 4dhu is ON HOLD until Jul 31 2014

	Authors: Thiel, P., Roeglin, L., Kohlbacher, O., Ottmann, C.		Authors: Thiel, P., Roeglin, L., Kohlbacher, O., Ottmann, C.

	Description: Small-molecule inhibitors of 14-3-3 protein-protein interactions from virtual screening		Description: Small-molecule inhibitors of 14-3-3 protein-protein interactions from virtual screening

OCA at 06:20, 15 February 2012

OCA — Wed, 15 Feb 2012 06:20:52 GMT

←Older revision		Revision as of 06:20, 15 February 2012
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 4dhu is ON HOLD	+	The entry 4dhu is ON HOLD until Paper Publication

	Authors: Thiel, P., Roeglin, L., Kohlbacher, O., Ottmann, C.		Authors: Thiel, P., Roeglin, L., Kohlbacher, O., Ottmann, C.

	Description: Small-molecule inhibitors of 14-3-3 protein-protein interactions from virtual screening		Description: Small-molecule inhibitors of 14-3-3 protein-protein interactions from virtual screening

OCA: Protected "4dhu" [edit=sysop:move=sysop]

OCA — Wed, 08 Feb 2012 06:12:38 GMT

Protected "4dhu" [edit=sysop:move=sysop]

←Older revision

Revision as of 06:12, 8 February 2012

OCA: New page: '''Unreleased structure''' The entry 4dhu is ON HOLD Authors: Thiel, P., Roeglin, L., Kohlbacher, O., Ottmann, C. Description: Small-molecule inhibitors of 14-3-3 protein-protein inter...

OCA — Wed, 08 Feb 2012 06:12:37 GMT

New page: '''Unreleased structure''' The entry 4dhu is ON HOLD Authors: Thiel, P., Roeglin, L., Kohlbacher, O., Ottmann, C. Description: Small-molecule inhibitors of 14-3-3 protein-protein inter...

New page

'''Unreleased structure'''

The entry 4dhu is ON HOLD

Authors: Thiel, P., Roeglin, L., Kohlbacher, O., Ottmann, C.

Description: Small-molecule inhibitors of 14-3-3 protein-protein interactions from virtual screening