4ela - Revision history

OCA at 07:16, 28 September 2022

OCA — Wed, 28 Sep 2022 07:16:07 GMT

←Older revision		Revision as of 07:16, 28 September 2022
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	<StructureSection load='4ela' size='340' side='right'caption='[[4ela]], [[Resolution\|resolution]] 2.00Å' scene=''>		<StructureSection load='4ela' size='340' side='right'caption='[[4ela]], [[Resolution\|resolution]] 2.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4ela]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Thaumatococcus_daniellii Thaumatococcus daniellii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ELA OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4ELA FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4ela]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Thaumatococcus_daniellii Thaumatococcus daniellii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ELA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4ELA FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=TLA:L(+)-TARTARIC+ACID'>TLA</scene>~~</td></tr>~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=TLA:L(+)-TARTARIC+ACID'>TLA</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4ek0\|4ek0]], [[4eka\|4eka]], [[4ekb\|4ekb]], [[4ekh\|4ekh]], [[4eko\|4eko]], [[4ekt\|4ekt]], [[4el2\|4el2]], [[4el3\|4el3]], [[4el7\|4el7]]</td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ela FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ela OCA], [https://pdbe.org/4ela PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ela RCSB], [https://www.ebi.ac.uk/pdbsum/4ela PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ela ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4ela FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ela OCA], [~~http~~://pdbe.org/4ela PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4ela RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4ela PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4ela ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/THM1_THADA THM1_THADA]] Taste-modifying protein; intensely sweet-tasting. It is 100000 times sweeter than sucrose on a molar basis.	+	[[https://www.uniprot.org/uniprot/THM1_THADA THM1_THADA]] Taste-modifying protein; intensely sweet-tasting. It is 100000 times sweeter than sucrose on a molar basis.
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Thaumatococcus daniellii]]		[[Category: Thaumatococcus daniellii]]
-	[[Category: Badeau, R]]	+	[[Category: Badeau R]]
-	[[Category: Hopkins~~, J B~~]]	+	[[Category: Hopkins JB]]
-	[[Category: Thorne~~, R E~~]]	+	[[Category: Thorne RE]]
-	[[Category: Warkentin, M]]	+	[[Category: Warkentin M]]
-	~~[[Category: Plant protein]]~~	+
-	~~[[Category: Radiation damage]]~~	+
-	~~[[Category: Sweet protein~~]]	+

OCA at 08:00, 27 March 2019

OCA — Wed, 27 Mar 2019 08:00:57 GMT

←Older revision		Revision as of 08:00, 27 March 2019
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	==Final Thaumatin Structure for Radiation Damage Experiment at 300 K==		==Final Thaumatin Structure for Radiation Damage Experiment at 300 K==
-	<StructureSection load='4ela' size='340' side='right' caption='[[4ela]], [[Resolution\|resolution]] 2.00Å' scene=''>	+	<StructureSection load='4ela' size='340' side='right'caption='[[4ela]], [[Resolution\|resolution]] 2.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4ela]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Thaumatococcus_daniellii Thaumatococcus daniellii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ELA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ELA FirstGlance]. <br>		<table><tr><td colspan='2'>[[4ela]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Thaumatococcus_daniellii Thaumatococcus daniellii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ELA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ELA FirstGlance]. <br>
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Thaumatococcus daniellii]]		[[Category: Thaumatococcus daniellii]]
	[[Category: Badeau, R]]		[[Category: Badeau, R]]

OCA at 08:46, 5 August 2016

OCA — Fri, 05 Aug 2016 08:46:19 GMT

←Older revision		Revision as of 08:46, 5 August 2016
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		+
	==Final Thaumatin Structure for Radiation Damage Experiment at 300 K==		==Final Thaumatin Structure for Radiation Damage Experiment at 300 K==
	<StructureSection load='4ela' size='340' side='right' caption='[[4ela]], [[Resolution\|resolution]] 2.00Å' scene=''>		<StructureSection load='4ela' size='340' side='right' caption='[[4ela]], [[Resolution\|resolution]] 2.00Å' scene=''>
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	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=TLA:L(+)-TARTARIC+ACID'>TLA</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=TLA:L(+)-TARTARIC+ACID'>TLA</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4ek0\|4ek0]], [[4eka\|4eka]], [[4ekb\|4ekb]], [[4ekh\|4ekh]], [[4eko\|4eko]], [[4ekt\|4ekt]], [[4el2\|4el2]], [[4el3\|4el3]], [[4el7\|4el7]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4ek0\|4ek0]], [[4eka\|4eka]], [[4ekb\|4ekb]], [[4ekh\|4ekh]], [[4eko\|4eko]], [[4ekt\|4ekt]], [[4el2\|4el2]], [[4el3\|4el3]], [[4el7\|4el7]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ela FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ela OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4ela RCSB], [http://www.ebi.ac.uk/pdbsum/4ela PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ela FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ela OCA], [http://pdbe.org/4ela PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4ela RCSB], [http://www.ebi.ac.uk/pdbsum/4ela PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4ela ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
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	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 4ela" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 17:23, 25 December 2014

OCA — Thu, 25 Dec 2014 17:23:45 GMT

←Older revision		Revision as of 17:23, 25 December 2014
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-	[[~~Image:~~4ela.~~png~~\|~~left~~\|~~200px~~]]	+	==Final Thaumatin Structure for Radiation Damage Experiment at 300 K==
		+	<StructureSection load='4ela' size='340' side='right' caption='[[4ela]], [[Resolution\|resolution]] 2.00Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[4ela]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Thaumatococcus_daniellii Thaumatococcus daniellii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ELA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ELA FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=TLA:L(+)-TARTARIC+ACID'>TLA</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4ek0\|4ek0]], [[4eka\|4eka]], [[4ekb\|4ekb]], [[4ekh\|4ekh]], [[4eko\|4eko]], [[4ekt\|4ekt]], [[4el2\|4el2]], [[4el3\|4el3]], [[4el7\|4el7]]</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ela FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ela OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4ela RCSB], [http://www.ebi.ac.uk/pdbsum/4ela PDBsum]</span></td></tr>
		+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/THM1_THADA THM1_THADA]] Taste-modifying protein; intensely sweet-tasting. It is 100000 times sweeter than sucrose on a molar basis.
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The spatial distribution of radiation damage (assayed by increases in atomic B factors) to thaumatin and urease crystals at temperatures ranging from 25 to 300 K is reported. The nature of the damage changes dramatically at approximately 180 K. Above this temperature the role of solvent diffusion is apparent in thaumatin crystals, as solvent-exposed turns and loops are especially sensitive. In urease, a flap covering the active site is the most sensitive part of the molecule and nearby loops show enhanced sensitivity. Below 180 K sensitivity is correlated with poor local packing, especially in thaumatin. At all temperatures, the component of the damage that is spatially uniform within the unit cell accounts for more than half of the total increase in the atomic B factors and correlates with changes in mosaicity. This component may arise from lattice-level, rather than local, disorder. The effects of primary structure on radiation sensitivity are small compared with those of tertiary structure, local packing, solvent accessibility and crystal contacts.

-	~~{{STRUCTURE_4ela\| PDB=4ela \| SCENE= }}~~	+	Spatial distribution of radiation damage to crystalline proteins at 25-300 K.,Warkentin M, Badeau R, Hopkins JB, Thorne RE Acta Crystallogr D Biol Crystallogr. 2012 Sep;68(Pt 9):1108-17. doi:, 10.1107/S0907444912021361. Epub 2012 Aug 18. PMID:22948911<ref>PMID:22948911</ref>

-	~~===Final Thaumatin Structure for Radiation Damage Experiment at 300 K===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_22948911}}~~	+	== References ==
-		+	<references/>
-	==~~About this Structure~~==	+	__TOC__
-	~~[[4ela]] is a 1 chain structure with sequence from [http:~~//~~en.wikipedia.org/wiki/Thaumatococcus_daniellii Thaumatococcus daniellii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ELA OCA].~~	+	</StructureSection>
	[[Category: Thaumatococcus daniellii]]		[[Category: Thaumatococcus daniellii]]
-	[[Category: Badeau, R.]]	+	[[Category: Badeau, R]]
-	[[Category: Hopkins, J B.]]	+	[[Category: Hopkins, J B]]
-	[[Category: Thorne, R E.]]	+	[[Category: Thorne, R E]]
-	[[Category: Warkentin, M.]]	+	[[Category: Warkentin, M]]
	[[Category: Plant protein]]		[[Category: Plant protein]]
	[[Category: Radiation damage]]		[[Category: Radiation damage]]
	[[Category: Sweet protein]]		[[Category: Sweet protein]]

OCA at 11:37, 23 January 2013

OCA — Wed, 23 Jan 2013 11:37:47 GMT

←Older revision		Revision as of 11:37, 23 January 2013
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-	[[Image:4ela.~~jpg~~\|left\|200px]]	+	[[Image:4ela.png\|left\|200px]]

	{{STRUCTURE_4ela\| PDB=4ela \| SCENE= }}		{{STRUCTURE_4ela\| PDB=4ela \| SCENE= }}
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	===Final Thaumatin Structure for Radiation Damage Experiment at 300 K===		===Final Thaumatin Structure for Radiation Damage Experiment at 300 K===

		+	{{ABSTRACT_PUBMED_22948911}}

	==About this Structure==		==About this Structure==

OCA at 05:24, 29 August 2012

OCA — Wed, 29 Aug 2012 05:24:28 GMT

←Older revision		Revision as of 05:24, 29 August 2012
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-	~~'''Unreleased structure'''~~	+	[[Image:4ela.jpg\|left\|200px]]

-	~~The entry~~ 4ela ~~is ON HOLD~~ ~~until Paper Publication~~	+	{{STRUCTURE_4ela\| PDB=4ela \| SCENE= }}

-	~~Authors: Warkentin, M., Badeau, R., Hopkins, J.B., Thorne, R.E.~~	+	===Final Thaumatin Structure for Radiation Damage Experiment at 300 K===

-	~~Description: Final Thaumatin~~ Structure ~~for~~ Radiation ~~Damage Experiment at 300 K~~	+
		+	==About this Structure==
		+	[[4ela]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Thaumatococcus_daniellii Thaumatococcus daniellii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ELA OCA].
		+	[[Category: Thaumatococcus daniellii]]
		+	[[Category: Badeau, R.]]
		+	[[Category: Hopkins, J B.]]
		+	[[Category: Thorne, R E.]]
		+	[[Category: Warkentin, M.]]
		+	[[Category: Plant protein]]
		+	[[Category: Radiation damage]]
		+	[[Category: Sweet protein]]

OCA at 18:56, 2 May 2012

OCA — Wed, 02 May 2012 18:56:19 GMT

←Older revision		Revision as of 18:56, 2 May 2012
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	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 4ela is ON HOLD	+	The entry 4ela is ON HOLD until Paper Publication

	Authors: Warkentin, M., Badeau, R., Hopkins, J.B., Thorne, R.E.		Authors: Warkentin, M., Badeau, R., Hopkins, J.B., Thorne, R.E.

	Description: Final Thaumatin Structure for Radiation Damage Experiment at 300 K		Description: Final Thaumatin Structure for Radiation Damage Experiment at 300 K

OCA: Protected "4ela" [edit=sysop:move=sysop]

OCA — Wed, 18 Apr 2012 07:34:30 GMT

Protected "4ela" [edit=sysop:move=sysop]

←Older revision

Revision as of 07:34, 18 April 2012

OCA: New page: '''Unreleased structure''' The entry 4ela is ON HOLD Authors: Warkentin, M., Badeau, R., Hopkins, J.B., Thorne, R.E. Description: Final Thaumatin Structure for Radiation Damage Experim...

OCA — Wed, 18 Apr 2012 07:34:29 GMT

New page: '''Unreleased structure''' The entry 4ela is ON HOLD Authors: Warkentin, M., Badeau, R., Hopkins, J.B., Thorne, R.E. Description: Final Thaumatin Structure for Radiation Damage Experim...

New page

'''Unreleased structure'''

The entry 4ela is ON HOLD

Authors: Warkentin, M., Badeau, R., Hopkins, J.B., Thorne, R.E.

Description: Final Thaumatin Structure for Radiation Damage Experiment at 300 K