4fel - Revision history

OCA at 11:15, 1 March 2024

OCA — Fri, 01 Mar 2024 11:15:38 GMT

←Older revision		Revision as of 11:15, 1 March 2024
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4fel]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FEL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4FEL FirstGlance]. <br>		<table><tr><td colspan='2'>[[4fel]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FEL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4FEL FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=HPA:HYPOXANTHINE'>HPA</scene>, <scene name='pdbligand=NCO:COBALT+HEXAMMINE(III)'>NCO</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.6Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=HPA:HYPOXANTHINE'>HPA</scene>, <scene name='pdbligand=NCO:COBALT+HEXAMMINE(III)'>NCO</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4fel FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4fel OCA], [https://pdbe.org/4fel PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4fel RCSB], [https://www.ebi.ac.uk/pdbsum/4fel PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4fel ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4fel FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4fel OCA], [https://pdbe.org/4fel PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4fel RCSB], [https://www.ebi.ac.uk/pdbsum/4fel PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4fel ProSAT]</span></td></tr>
	</table>		</table>
-	<div style="background-color:#fffaf0;">
-	== Publication Abstract from PubMed ==
-	Direct sensing of intracellular metabolite concentrations by riboswitch RNAs provides an economical and rapid means to maintain metabolic homeostasis. Since many organisms employ the same class of riboswitch to control different genes or transcription units, it is likely that functional variation exists in riboswitches such that activity is tuned to meet cellular needs. Using a bioinformatic approach, we have identified a region of the purine riboswitch aptamer domain that displays conservation patterns linked to riboswitch activity. Aptamer domain compositions within this region can be divided into nine classes that display a spectrum of activities. Naturally occurring compositions in this region favor rapid association rate constants and slow dissociation rate constants for ligand binding. Using X-ray crystallography and chemical probing, we demonstrate that both the free and bound states are influenced by the composition of this region and that modest sequence alterations have a dramatic impact on activity. The introduction of non-natural compositions result in the inability to regulate gene expression in vivo, suggesting that aptamer domain activity is highly plastic and thus readily tunable to meet cellular needs.
-
-	Nucleotides Adjacent to the Ligand-Binding Pocket are Linked to Activity Tuning in the Purine Riboswitch.,Stoddard CD, Widmann J, Trausch JJ, Marcano-Velazquez JG, Knight R, Batey RT J Mol Biol. 2013 Feb 26. pii: S0022-2836(13)00125-3. doi:, 10.1016/j.jmb.2013.02.023. PMID:23485418<ref>PMID:23485418</ref>
-
-	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	</div>
-	<div class="pdbe-citations 4fel" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
	*[[Riboswitch 3D structures\|Riboswitch 3D structures]]		*[[Riboswitch 3D structures\|Riboswitch 3D structures]]
-	== References ==
-	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>

OCA at 04:52, 7 October 2022

OCA — Fri, 07 Oct 2022 04:52:30 GMT

←Older revision		Revision as of 04:52, 7 October 2022
Line 3:		Line 3:
	<StructureSection load='4fel' size='340' side='right'caption='[[4fel]], [[Resolution\|resolution]] 1.60Å' scene=''>		<StructureSection load='4fel' size='340' side='right'caption='[[4fel]], [[Resolution\|resolution]] 1.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4fel]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FEL OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4FEL FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4fel]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FEL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4FEL FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=HPA:HYPOXANTHINE'>HPA</scene>, <scene name='pdbligand=NCO:COBALT+HEXAMMINE(III)'>NCO</scene>~~</td></tr>~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=HPA:HYPOXANTHINE'>HPA</scene>, <scene name='pdbligand=NCO:COBALT+HEXAMMINE(III)'>NCO</scene></td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1u8d\|1u8d]], [[4fe5\|4fe5]], [[4fej\|4fej]], [[4fen\|4fen]], [[4feo\|4feo]], [[4fep\|4fep]]~~</td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4fel FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4fel OCA], [https://pdbe.org/4fel PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4fel RCSB], [https://www.ebi.ac.uk/pdbsum/4fel PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4fel ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4fel FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4fel OCA], [~~http~~://pdbe.org/4fel PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4fel RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4fel PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4fel ProSAT]</span></td></tr>	+
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 19:		Line 18:

	==See Also==		==See Also==
-	*[[Riboswitch\|Riboswitch]]	+	*[[Riboswitch 3D structures\|Riboswitch 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Bacillus subtilis]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Batey~~, R T~~]]	+	[[Category: Batey RT]]
-	[[Category: Knight, R]]	+	[[Category: Knight R]]
-	[[Category: Marcano, J]]	+	[[Category: Marcano J]]
-	[[Category: Stoddard~~, C D~~]]	+	[[Category: Stoddard CD]]
-	[[Category: Trausch~~, J J~~]]	+	[[Category: Trausch JJ]]
-	[[Category: Widmann, J]]	+	[[Category: Widmann J]]
-	~~[[Category: Genetic regulatory element]]~~	+
-	~~[[Category: Hypoxanthine]]~~	+
-	~~[[Category: Rna]]~~	+
-	~~[[Category: Three-way junction with distal tertiary interaction~~]]	+

OCA at 07:25, 27 March 2019

OCA — Wed, 27 Mar 2019 07:25:18 GMT

←Older revision		Revision as of 07:25, 27 March 2019
Line 1:		Line 1:

	==Crystal structure of the U25A/A46G mutant of the xpt-pbuX guanine riboswitch aptamer domain in complex with hypoxanthine==		==Crystal structure of the U25A/A46G mutant of the xpt-pbuX guanine riboswitch aptamer domain in complex with hypoxanthine==
-	<StructureSection load='4fel' size='340' side='right' caption='[[4fel]], [[Resolution\|resolution]] 1.60Å' scene=''>	+	<StructureSection load='4fel' size='340' side='right'caption='[[4fel]], [[Resolution\|resolution]] 1.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4fel]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FEL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4FEL FirstGlance]. <br>		<table><tr><td colspan='2'>[[4fel]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FEL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4FEL FirstGlance]. <br>
Line 24:		Line 24:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Batey, R T]]		[[Category: Batey, R T]]
	[[Category: Knight, R]]		[[Category: Knight, R]]

OCA at 12:31, 11 August 2016

OCA — Thu, 11 Aug 2016 12:31:41 GMT

←Older revision		Revision as of 12:31, 11 August 2016
Line 1:		Line 1:
		+
	==Crystal structure of the U25A/A46G mutant of the xpt-pbuX guanine riboswitch aptamer domain in complex with hypoxanthine==		==Crystal structure of the U25A/A46G mutant of the xpt-pbuX guanine riboswitch aptamer domain in complex with hypoxanthine==
	<StructureSection load='4fel' size='340' side='right' caption='[[4fel]], [[Resolution\|resolution]] 1.60Å' scene=''>		<StructureSection load='4fel' size='340' side='right' caption='[[4fel]], [[Resolution\|resolution]] 1.60Å' scene=''>
Line 5:		Line 6:
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=HPA:HYPOXANTHINE'>HPA</scene>, <scene name='pdbligand=NCO:COBALT+HEXAMMINE(III)'>NCO</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=HPA:HYPOXANTHINE'>HPA</scene>, <scene name='pdbligand=NCO:COBALT+HEXAMMINE(III)'>NCO</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1u8d\|1u8d]], [[4fe5\|4fe5]], [[4fej\|4fej]], [[4fen\|4fen]], [[4feo\|4feo]], [[4fep\|4fep]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1u8d\|1u8d]], [[4fe5\|4fe5]], [[4fej\|4fej]], [[4fen\|4fen]], [[4feo\|4feo]], [[4fep\|4fep]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4fel FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4fel OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4fel RCSB], [http://www.ebi.ac.uk/pdbsum/4fel PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4fel FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4fel OCA], [http://pdbe.org/4fel PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4fel RCSB], [http://www.ebi.ac.uk/pdbsum/4fel PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4fel ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 15:		Line 16:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 4fel" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==

OCA at 12:21, 4 January 2015

OCA — Sun, 04 Jan 2015 12:21:19 GMT

←Older revision		Revision as of 12:21, 4 January 2015
Line 1:		Line 1:
-	~~{{STRUCTURE_4fel\| PDB=4fel \| SCENE= }}~~	+	==Crystal structure of the U25A/A46G mutant of the xpt-pbuX guanine riboswitch aptamer domain in complex with hypoxanthine==
-	===Crystal structure of the U25A/A46G mutant of the xpt-pbuX guanine riboswitch aptamer domain in complex with hypoxanthine===	+	<StructureSection load='4fel' size='340' side='right' caption='[[4fel]], [[Resolution\|resolution]] 1.60Å' scene=''>
-	~~{{ABSTRACT_PUBMED_23485418}}~~	+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[4fel]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FEL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4FEL FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=HPA:HYPOXANTHINE'>HPA</scene>, <scene name='pdbligand=NCO:COBALT+HEXAMMINE(III)'>NCO</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1u8d\|1u8d]], [[4fe5\|4fe5]], [[4fej\|4fej]], [[4fen\|4fen]], [[4feo\|4feo]], [[4fep\|4fep]]</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4fel FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4fel OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4fel RCSB], [http://www.ebi.ac.uk/pdbsum/4fel PDBsum]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Direct sensing of intracellular metabolite concentrations by riboswitch RNAs provides an economical and rapid means to maintain metabolic homeostasis. Since many organisms employ the same class of riboswitch to control different genes or transcription units, it is likely that functional variation exists in riboswitches such that activity is tuned to meet cellular needs. Using a bioinformatic approach, we have identified a region of the purine riboswitch aptamer domain that displays conservation patterns linked to riboswitch activity. Aptamer domain compositions within this region can be divided into nine classes that display a spectrum of activities. Naturally occurring compositions in this region favor rapid association rate constants and slow dissociation rate constants for ligand binding. Using X-ray crystallography and chemical probing, we demonstrate that both the free and bound states are influenced by the composition of this region and that modest sequence alterations have a dramatic impact on activity. The introduction of non-natural compositions result in the inability to regulate gene expression in vivo, suggesting that aptamer domain activity is highly plastic and thus readily tunable to meet cellular needs.

-	~~==About this Structure==~~	+	Nucleotides Adjacent to the Ligand-Binding Pocket are Linked to Activity Tuning in the Purine Riboswitch.,Stoddard CD, Widmann J, Trausch JJ, Marcano-Velazquez JG, Knight R, Batey RT J Mol Biol. 2013 Feb 26. pii: S0022-2836(13)00125-3. doi:, 10.1016/j.jmb.2013.02.023. PMID:23485418<ref>PMID:23485418</ref>
-	~~[[4fel]] is a 1 chain structure~~. ~~Full crystallographic information is available from [http~~:/~~/oca~~.~~weizmann~~.ac.~~il/oca-bin/ocashort?id=4FEL OCA]~~.	+

-	==~~Reference~~==	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	~~<ref group~~=~~"xtra">PMID:023485418</ref>~~<references ~~group="xtra"~~/><~~references~~/>	+	</div>
-	[[Category: Batey, R T.]]	+
-	[[Category: Knight, R.]]	+	==See Also==
-	[[Category: Marcano, J.]]	+	*[[Riboswitch\|Riboswitch]]
-	[[Category: Stoddard, C D.]]	+	== References ==
-	[[Category: Trausch, J J.]]	+	<references/>
-	[[Category: Widmann, J.]]	+	__TOC__
		+	</StructureSection>
		+	[[Category: Batey, R T]]
		+	[[Category: Knight, R]]
		+	[[Category: Marcano, J]]
		+	[[Category: Stoddard, C D]]
		+	[[Category: Trausch, J J]]
		+	[[Category: Widmann, J]]
	[[Category: Genetic regulatory element]]		[[Category: Genetic regulatory element]]
	[[Category: Hypoxanthine]]		[[Category: Hypoxanthine]]
	[[Category: Rna]]		[[Category: Rna]]
	[[Category: Three-way junction with distal tertiary interaction]]		[[Category: Three-way junction with distal tertiary interaction]]

OCA at 06:33, 20 June 2013

OCA — Thu, 20 Jun 2013 06:33:46 GMT

←Older revision		Revision as of 06:33, 20 June 2013
Line 5:		Line 5:
	==About this Structure==		==About this Structure==
	[[4fel]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FEL OCA].		[[4fel]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FEL OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:023485418</ref><references group="xtra"/><references/>
	[[Category: Batey, R T.]]		[[Category: Batey, R T.]]
	[[Category: Knight, R.]]		[[Category: Knight, R.]]

OCA at 07:41, 27 March 2013

OCA — Wed, 27 Mar 2013 07:41:13 GMT

←Older revision		Revision as of 07:41, 27 March 2013
Line 1:		Line 1:
-	[[Image:4fel.jpg\|left\|200px]]
-
	{{STRUCTURE_4fel\| PDB=4fel \| SCENE= }}		{{STRUCTURE_4fel\| PDB=4fel \| SCENE= }}
-
	===Crystal structure of the U25A/A46G mutant of the xpt-pbuX guanine riboswitch aptamer domain in complex with hypoxanthine===		===Crystal structure of the U25A/A46G mutant of the xpt-pbuX guanine riboswitch aptamer domain in complex with hypoxanthine===
-		+	{{ABSTRACT_PUBMED_23485418}}

	==About this Structure==		==About this Structure==

OCA at 14:57, 27 February 2013

OCA — Wed, 27 Feb 2013 14:57:07 GMT

←Older revision		Revision as of 14:57, 27 February 2013
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	[[Image:4fel.jpg\|left\|200px]]

-	~~The entry~~ 4fel ~~is ON HOLD~~ ~~until Paper Publication~~	+	{{STRUCTURE_4fel\| PDB=4fel \| SCENE= }}

-	~~Authors: Stoddard, C.D., Trausch, J.J., Widmann, J., Marcano, J., Knight, R., Batey, R.T.~~	+	===Crystal structure of the U25A/A46G mutant of the xpt-pbuX guanine riboswitch aptamer domain in complex with hypoxanthine===

-	~~Description: Crystal~~ structure ~~of the U25A~~/~~A46G mutant of the xpt~~-~~pbuX guanine riboswitch aptamer domain in complex~~ with ~~hypoxanthine~~	+
		+	==About this Structure==
		+	[[4fel]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FEL OCA].
		+	[[Category: Batey, R T.]]
		+	[[Category: Knight, R.]]
		+	[[Category: Marcano, J.]]
		+	[[Category: Stoddard, C D.]]
		+	[[Category: Trausch, J J.]]
		+	[[Category: Widmann, J.]]
		+	[[Category: Genetic regulatory element]]
		+	[[Category: Hypoxanthine]]
		+	[[Category: Rna]]
		+	[[Category: Three-way junction with distal tertiary interaction]]

OCA at 05:23, 27 June 2012

OCA — Wed, 27 Jun 2012 05:23:41 GMT

←Older revision		Revision as of 05:23, 27 June 2012
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 4fel is ON HOLD	+	The entry 4fel is ON HOLD until Paper Publication

	Authors: Stoddard, C.D., Trausch, J.J., Widmann, J., Marcano, J., Knight, R., Batey, R.T.		Authors: Stoddard, C.D., Trausch, J.J., Widmann, J., Marcano, J., Knight, R., Batey, R.T.

	Description: Crystal structure of the U25A/A46G mutant of the xpt-pbuX guanine riboswitch aptamer domain in complex with hypoxanthine		Description: Crystal structure of the U25A/A46G mutant of the xpt-pbuX guanine riboswitch aptamer domain in complex with hypoxanthine

OCA at 07:24, 20 June 2012

OCA — Wed, 20 Jun 2012 07:24:45 GMT

←Older revision		Revision as of 07:24, 20 June 2012
Line 3:		Line 3:
	The entry 4fel is ON HOLD		The entry 4fel is ON HOLD

-	Authors: Stoddard, C.D., Trausch, J. J., Widmann, J., Marcano, J., Knight, R., Batey, R.T.	+	Authors: Stoddard, C.D., Trausch, J.J., Widmann, J., Marcano, J., Knight, R., Batey, R.T.

	Description: Crystal structure of the U25A/A46G mutant of the xpt-pbuX guanine riboswitch aptamer domain in complex with hypoxanthine		Description: Crystal structure of the U25A/A46G mutant of the xpt-pbuX guanine riboswitch aptamer domain in complex with hypoxanthine