4fnm - Revision history

OCA at 15:30, 14 March 2024

OCA — Thu, 14 Mar 2024 15:30:19 GMT

←Older revision		Revision as of 15:30, 14 March 2024
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4fnm]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Lucilia_cuprina Lucilia cuprina]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FNM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4FNM FirstGlance]. <br>		<table><tr><td colspan='2'>[[4fnm]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Lucilia_cuprina Lucilia cuprina]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FNM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4FNM FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DPF:DIETHYL+HYDROGEN+PHOSPHATE'>DPF</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.804Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DPF:DIETHYL+HYDROGEN+PHOSPHATE'>DPF</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4fnm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4fnm OCA], [https://pdbe.org/4fnm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4fnm RCSB], [https://www.ebi.ac.uk/pdbsum/4fnm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4fnm ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4fnm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4fnm OCA], [https://pdbe.org/4fnm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4fnm RCSB], [https://www.ebi.ac.uk/pdbsum/4fnm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4fnm ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[https://www.uniprot.org/uniprot/Q25252_LUCCU Q25252_LUCCU]		[https://www.uniprot.org/uniprot/Q25252_LUCCU Q25252_LUCCU]
-	<div style="background-color:#fffaf0;">
-	== Publication Abstract from PubMed ==
-	Insect carboxylesterases from the alphaEsterase gene cluster, such as alphaE7 (also known as E3) from the Australian sheep blowfly Lucilia cuprina (LcalphaE7), play an important physiological role in lipid metabolism and are implicated in the detoxification of organophosphate (OP) insecticides. Despite the importance of OPs to agriculture and the spread of insect-borne diseases, the molecular basis for the ability of alpha-carboxylesterases to confer OP resistance to insects is poorly understood. In this work, we used laboratory evolution to increase the thermal stability of LcalphaE7, allowing its overexpression in Escherichia coli and structure determination. The crystal structure reveals a canonical alpha/beta-hydrolase fold that is very similar to the primary target of OPs (acetylcholinesterase) and a unique N-terminal alpha-helix that serves as a membrane anchor. Soaking of LcalphaE7 crystals in OPs led to the capture of a crystallographic snapshot of LcalphaE7 in its phosphorylated state, which allowed comparison with acetylcholinesterase and rationalization of its ability to protect insects against the effects of OPs. Finally, inspection of the active site of LcalphaE7 reveals an asymmetric and hydrophobic substrate binding cavity that is well-suited to fatty acid methyl esters, which are hydrolyzed by the enzyme with specificity constants ( approximately 10(6) M(-1) s(-1)) indicative of a natural substrate.
-
-	Structure and function of an insect alpha-carboxylesterase (alphaEsterase7) associated with insecticide resistance.,Jackson CJ, Liu JW, Carr PD, Younus F, Coppin C, Meirelles T, Lethier M, Pandey G, Ollis DL, Russell RJ, Weik M, Oakeshott JG Proc Natl Acad Sci U S A. 2013 Jun 18;110(25):10177-82. doi:, 10.1073/pnas.1304097110. Epub 2013 Jun 3. PMID:23733941<ref>PMID:23733941</ref>
-
-	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	</div>
-	<div class="pdbe-citations 4fnm" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
	*[[Carboxylesterase 3D structures\|Carboxylesterase 3D structures]]		*[[Carboxylesterase 3D structures\|Carboxylesterase 3D structures]]
-	== References ==
-	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>

OCA at 20:01, 19 October 2022

OCA — Wed, 19 Oct 2022 20:01:50 GMT

←Older revision		Revision as of 20:01, 19 October 2022
Line 1:		Line 1:

	==The alpha-esterase-7 carboxylesterase, E3, from the blowfly Lucilia cuprina==		==The alpha-esterase-7 carboxylesterase, E3, from the blowfly Lucilia cuprina==
-	<StructureSection load='4fnm' size='340' side='right' caption='[[4fnm]], [[Resolution\|resolution]] 1.80Å' scene=''>	+	<StructureSection load='4fnm' size='340' side='right'caption='[[4fnm]], [[Resolution\|resolution]] 1.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4fnm]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Australian_sheep_blowfly Australian sheep blowfly~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FNM OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4FNM FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4fnm]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Lucilia_cuprina Lucilia cuprina]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FNM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4FNM FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DPF:DIETHYL+HYDROGEN+PHOSPHATE'>DPF</scene>~~</td></tr>~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DPF:DIETHYL+HYDROGEN+PHOSPHATE'>DPF</scene></td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4fg5\|4fg5]], [[4fng\|4fng]]</td></tr>~~	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4fnm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4fnm OCA], [https://pdbe.org/4fnm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4fnm RCSB], [https://www.ebi.ac.uk/pdbsum/4fnm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4fnm ProSAT]</span></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">LcaE7 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7375 Australian sheep blowfly])</td></tr>	+
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4fnm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4fnm OCA], [~~http~~://pdbe.org/4fnm PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4fnm RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4fnm PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4fnm ProSAT]</span></td></tr>	+
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/Q25252_LUCCU Q25252_LUCCU]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 20:		Line 20:

	==See Also==		==See Also==
-	*[[Carboxylesterase\|Carboxylesterase]]	+	*[[Carboxylesterase 3D structures\|Carboxylesterase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Australian sheep blowfly~~]]	+	[[Category: Large Structures]]
-	[[Category: Carr~~, P D~~]]	+	[[Category: Lucilia cuprina]]
-	[[Category: Coppin, C]]	+	[[Category: Carr PD]]
-	[[Category: Jackson~~, C J~~]]	+	[[Category: Coppin C]]
-	[[Category: Liu, J W]]	+	[[Category: Jackson CJ]]
-	[[Category: Meirelles, T]]	+	[[Category: Liu J-W]]
-	[[Category: Oakeshott~~, J G~~]]	+	[[Category: Meirelles T]]
-	[[Category: Ollis~~, D L~~]]	+	[[Category: Oakeshott JG]]
-	[[Category: Pandey, G]]	+	[[Category: Ollis DL]]
-	[[Category: Tawfik~~, D S~~]]	+	[[Category: Pandey G]]
-	[[Category: Weik, M]]	+	[[Category: Tawfik DS]]
-	[[Category: Younis, F]]	+	[[Category: Weik M]]
-	~~[[Category: Alpha/beta hydrolase fold]]~~	+	[[Category: Younis F]]
-	~~[[Category: Carboxylesterase]]~~	+
-	~~[[Category: Hydrolase~~]]	+

OCA at 00:54, 5 August 2016

OCA — Fri, 05 Aug 2016 00:54:01 GMT

←Older revision		Revision as of 00:54, 5 August 2016
Line 1:		Line 1:
		+
	==The alpha-esterase-7 carboxylesterase, E3, from the blowfly Lucilia cuprina==		==The alpha-esterase-7 carboxylesterase, E3, from the blowfly Lucilia cuprina==
	<StructureSection load='4fnm' size='340' side='right' caption='[[4fnm]], [[Resolution\|resolution]] 1.80Å' scene=''>		<StructureSection load='4fnm' size='340' side='right' caption='[[4fnm]], [[Resolution\|resolution]] 1.80Å' scene=''>
Line 6:		Line 7:
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4fg5\|4fg5]], [[4fng\|4fng]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4fg5\|4fg5]], [[4fng\|4fng]]</td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">LcaE7 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7375 Australian sheep blowfly])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">LcaE7 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7375 Australian sheep blowfly])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4fnm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4fnm OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4fnm RCSB], [http://www.ebi.ac.uk/pdbsum/4fnm PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4fnm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4fnm OCA], [http://pdbe.org/4fnm PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4fnm RCSB], [http://www.ebi.ac.uk/pdbsum/4fnm PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4fnm ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 16:		Line 17:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 4fnm" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==

OCA at 17:26, 21 December 2014

OCA — Sun, 21 Dec 2014 17:26:09 GMT

←Older revision		Revision as of 17:26, 21 December 2014
Line 1:		Line 1:
-	~~{{STRUCTURE_4fnm\| PDB=4fnm \| SCENE= }}~~	+	==The alpha-esterase-7 carboxylesterase, E3, from the blowfly Lucilia cuprina==
-	===The alpha-esterase-7 carboxylesterase, E3, from the blowfly Lucilia cuprina===	+	<StructureSection load='4fnm' size='340' side='right' caption='[[4fnm]], [[Resolution\|resolution]] 1.80Å' scene=''>
-	~~{{ABSTRACT_PUBMED_23733941}}~~	+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[4fnm]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Australian_sheep_blowfly Australian sheep blowfly]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FNM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4FNM FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DPF:DIETHYL+HYDROGEN+PHOSPHATE'>DPF</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4fg5\|4fg5]], [[4fng\|4fng]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">LcaE7 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7375 Australian sheep blowfly])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4fnm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4fnm OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4fnm RCSB], [http://www.ebi.ac.uk/pdbsum/4fnm PDBsum]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Insect carboxylesterases from the alphaEsterase gene cluster, such as alphaE7 (also known as E3) from the Australian sheep blowfly Lucilia cuprina (LcalphaE7), play an important physiological role in lipid metabolism and are implicated in the detoxification of organophosphate (OP) insecticides. Despite the importance of OPs to agriculture and the spread of insect-borne diseases, the molecular basis for the ability of alpha-carboxylesterases to confer OP resistance to insects is poorly understood. In this work, we used laboratory evolution to increase the thermal stability of LcalphaE7, allowing its overexpression in Escherichia coli and structure determination. The crystal structure reveals a canonical alpha/beta-hydrolase fold that is very similar to the primary target of OPs (acetylcholinesterase) and a unique N-terminal alpha-helix that serves as a membrane anchor. Soaking of LcalphaE7 crystals in OPs led to the capture of a crystallographic snapshot of LcalphaE7 in its phosphorylated state, which allowed comparison with acetylcholinesterase and rationalization of its ability to protect insects against the effects of OPs. Finally, inspection of the active site of LcalphaE7 reveals an asymmetric and hydrophobic substrate binding cavity that is well-suited to fatty acid methyl esters, which are hydrolyzed by the enzyme with specificity constants ( approximately 10(6) M(-1) s(-1)) indicative of a natural substrate.

-	~~==About this~~ Structure==	+	Structure and function of an insect alpha-carboxylesterase (alphaEsterase7) associated with insecticide resistance.,Jackson CJ, Liu JW, Carr PD, Younus F, Coppin C, Meirelles T, Lethier M, Pandey G, Ollis DL, Russell RJ, Weik M, Oakeshott JG Proc Natl Acad Sci U S A. 2013 Jun 18;110(25):10177-82. doi:, 10.1073/pnas.1304097110. Epub 2013 Jun 3. PMID:23733941<ref>PMID:23733941</ref>
-	~~[[4fnm]] is a 1 chain structure~~. ~~Full crystallographic information is available from [http~~:/~~/oca~~.~~weizmann~~.ac.il/~~oca-bin/ocashort?id=4FNM OCA].~~	+

-	==~~Reference~~==	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	~~<ref group~~=~~"xtra">PMID:023733941</ref>~~<references ~~group="xtra"~~/><~~references~~/>	+	</div>
-	[[Category: Carr, P D.]]	+
-	[[Category: Coppin, C.]]	+	==See Also==
-	[[Category: Jackson, C J.]]	+	*[[Carboxylesterase\|Carboxylesterase]]
-	[[Category: Liu, J W.]]	+	== References ==
-	[[Category: Meirelles, T.]]	+	<references/>
-	[[Category: Oakeshott, J G.]]	+	__TOC__
-	[[Category: Ollis, D L.]]	+	</StructureSection>
-	[[Category: Pandey, G.]]	+	[[Category: Australian sheep blowfly]]
-	[[Category: Tawfik, D S.]]	+	[[Category: Carr, P D]]
-	[[Category: Weik, M.]]	+	[[Category: Coppin, C]]
-	[[Category: Younis, F.]]	+	[[Category: Jackson, C J]]
		+	[[Category: Liu, J W]]
		+	[[Category: Meirelles, T]]
		+	[[Category: Oakeshott, J G]]
		+	[[Category: Ollis, D L]]
		+	[[Category: Pandey, G]]
		+	[[Category: Tawfik, D S]]
		+	[[Category: Weik, M]]
		+	[[Category: Younis, F]]
	[[Category: Alpha/beta hydrolase fold]]		[[Category: Alpha/beta hydrolase fold]]
	[[Category: Carboxylesterase]]		[[Category: Carboxylesterase]]
	[[Category: Hydrolase]]		[[Category: Hydrolase]]

OCA at 07:19, 4 December 2013

OCA — Wed, 04 Dec 2013 07:19:30 GMT

←Older revision		Revision as of 07:19, 4 December 2013
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	{{STRUCTURE_4fnm\| PDB=4fnm \| SCENE= }}
		+	===The alpha-esterase-7 carboxylesterase, E3, from the blowfly Lucilia cuprina===
		+	{{ABSTRACT_PUBMED_23733941}}

-	~~The entry~~ 4fnm is ~~ON HOLD until Paper Publication~~	+	==About this Structure==
		+	[[4fnm]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FNM OCA].

-	~~Authors~~: ~~Jackson, C.J., Liu, J.-W.,~~ Carr, P.D., ~~Younis, F~~.~~, Pandey, G., Coppin~~, C., Meirelles, T., Ollis, D.L., Tawfik, D.S., Weik, M., ~~Oakeshott, J.G~~.	+	==Reference==
-		+	<ref group="xtra">PMID:023733941</ref><references group="xtra"/><references/>
-	~~Description~~: ~~The alpha-esterase-7 carboxylesterase, E3, from the blowfly Lucilia cuprina~~	+	[[Category: Carr, P D.]]
		+	[[Category: Coppin, C.]]
		+	[[Category: Jackson, C J.]]
		+	[[Category: Liu, J W.]]
		+	[[Category: Meirelles, T.]]
		+	[[Category: Oakeshott, J G.]]
		+	[[Category: Ollis, D L.]]
		+	[[Category: Pandey, G.]]
		+	[[Category: Tawfik, D S.]]
		+	[[Category: Weik, M.]]
		+	[[Category: Younis, F.]]
		+	[[Category: Alpha/beta hydrolase fold]]
		+	[[Category: Carboxylesterase]]
		+	[[Category: Hydrolase]]

OCA at 08:45, 2 January 2013

OCA — Wed, 02 Jan 2013 08:45:16 GMT

←Older revision		Revision as of 08:45, 2 January 2013
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 4fnm is ON HOLD	+	The entry 4fnm is ON HOLD until Paper Publication

	Authors: Jackson, C.J., Liu, J.-W., Carr, P.D., Younis, F., Pandey, G., Coppin, C., Meirelles, T., Ollis, D.L., Tawfik, D.S., Weik, M., Oakeshott, J.G.		Authors: Jackson, C.J., Liu, J.-W., Carr, P.D., Younis, F., Pandey, G., Coppin, C., Meirelles, T., Ollis, D.L., Tawfik, D.S., Weik, M., Oakeshott, J.G.

	Description: The alpha-esterase-7 carboxylesterase, E3, from the blowfly Lucilia cuprina		Description: The alpha-esterase-7 carboxylesterase, E3, from the blowfly Lucilia cuprina

OCA at 10:54, 19 December 2012

OCA — Wed, 19 Dec 2012 10:54:53 GMT

←Older revision		Revision as of 10:54, 19 December 2012
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 4fnm is ON HOLD ~~until sometime in the future~~	+	The entry 4fnm is ON HOLD

-	Authors: Jackson, C.J. , Liu,J-W. , Carr, P.D. , Younis, F. , Pandey, G. , Coppin, C. , Meirelles, T. , Ollis, D.L., Tawfik, D.S. , Weik, M., Oakeshott, J.G.	+	Authors: Jackson, C.J., Liu, J.-W., Carr, P.D., Younis, F., Pandey, G., Coppin, C., Meirelles, T., Ollis, D.L., Tawfik, D.S., Weik, M., Oakeshott, J.G.

	Description: The alpha-esterase-7 carboxylesterase, E3, from the blowfly Lucilia cuprina		Description: The alpha-esterase-7 carboxylesterase, E3, from the blowfly Lucilia cuprina

OCA at 06:46, 25 July 2012

OCA — Wed, 25 Jul 2012 06:46:10 GMT

←Older revision		Revision as of 06:46, 25 July 2012
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 4fnm is ON HOLD	+	The entry 4fnm is ON HOLD until sometime in the future

	Authors: Jackson, C.J. , Liu,J-W. , Carr, P.D. , Younis, F. , Pandey, G. , Coppin, C. , Meirelles, T. , Ollis, D.L., Tawfik, D.S. , Weik, M., Oakeshott, J.G.		Authors: Jackson, C.J. , Liu,J-W. , Carr, P.D. , Younis, F. , Pandey, G. , Coppin, C. , Meirelles, T. , Ollis, D.L., Tawfik, D.S. , Weik, M., Oakeshott, J.G.

	Description: The alpha-esterase-7 carboxylesterase, E3, from the blowfly Lucilia cuprina		Description: The alpha-esterase-7 carboxylesterase, E3, from the blowfly Lucilia cuprina

OCA: Protected "4fnm" [edit=sysop:move=sysop]

OCA — Wed, 27 Jun 2012 05:28:01 GMT

Protected "4fnm" [edit=sysop:move=sysop]

←Older revision

Revision as of 05:28, 27 June 2012

OCA: New page: '''Unreleased structure''' The entry 4fnm is ON HOLD Authors: Jackson, C.J. , Liu,J-W. , Carr, P.D. , Younis, F. , Pandey, G. , Coppin, C. , Meirelles, T. , Ollis, D.L., Tawfik, D.S. , ...

OCA — Wed, 27 Jun 2012 05:28:00 GMT

New page: '''Unreleased structure''' The entry 4fnm is ON HOLD Authors: Jackson, C.J. , Liu,J-W. , Carr, P.D. , Younis, F. , Pandey, G. , Coppin, C. , Meirelles, T. , Ollis, D.L., Tawfik, D.S. , ...

New page

'''Unreleased structure'''

The entry 4fnm is ON HOLD

Authors: Jackson, C.J. , Liu,J-W. , Carr, P.D. , Younis, F. , Pandey, G. , Coppin, C. , Meirelles, T. , Ollis, D.L., Tawfik, D.S. , Weik, M., Oakeshott, J.G.

Description: The alpha-esterase-7 carboxylesterase, E3, from the blowfly Lucilia cuprina