4g79 - Revision history

OCA at 20:28, 19 October 2022

OCA — Wed, 19 Oct 2022 20:28:51 GMT

←Older revision		Revision as of 20:28, 19 October 2022
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	==Structure a C. elegans SAS-6 variant==		==Structure a C. elegans SAS-6 variant==
-	<StructureSection load='4g79' size='340' side='right' caption='[[4g79]], [[Resolution\|resolution]] 1.80Å' scene=''>	+	<StructureSection load='4g79' size='340' side='right'caption='[[4g79]], [[Resolution\|resolution]] 1.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4g79]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Caeel Caeel~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4G79 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4G79 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4g79]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Caenorhabditis_elegans Caenorhabditis elegans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4G79 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4G79 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene>~~</td></tr>~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene></td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3pyi\|3pyi]], [[2y3v\|2y3v]], [[2y3w\|2y3w]], [[3q0y\|3q0y]], [[3q0x\|3q0x]]</td></tr>~~	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4g79 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4g79 OCA], [https://pdbe.org/4g79 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4g79 RCSB], [https://www.ebi.ac.uk/pdbsum/4g79 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4g79 ProSAT]</span></td></tr>
-	~~<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">sas-6, Y45F10D.9 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=6239 CAEEL])~~</td></tr>	+
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4g79 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4g79 OCA], [~~http~~://pdbe.org/4g79 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4g79 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4g79 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4g79 ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/SAS6_CAEEL SAS6_CAEEL]] Required for centrosome duplication. Participates in centriole assembly.<ref>PMID:15572125</ref> <ref>PMID:15665853</ref>	+	[https://www.uniprot.org/uniprot/SAS6_CAEEL SAS6_CAEEL] Required for centrosome duplication. Participates in centriole assembly.<ref>PMID:15572125</ref> <ref>PMID:15665853</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 24:		Line 22:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Caeel~~]]	+	[[Category: Caenorhabditis elegans]]
-	[[Category: ~~Erat, M C~~]]	+	[[Category: Large Structures]]
-	[[Category: ~~Vakonakis, I~~]]	+	[[Category: Erat MC]]
-	[[Category: ~~Alpha-beta protein]]~~	+	[[Category: Vakonakis I]]
-	~~[[Category: Beta-sandwich]]~~	+
-	~~[[Category: Central tube]]~~	+
-	~~[[Category: Centriolar]]~~	+
-	~~[[Category: Centriole]]~~	+
-	~~[[Category: Cytoplasmic]]~~	+
-	~~[[Category: Structural protein~~]]	+

OCA at 16:44, 4 August 2016

OCA — Thu, 04 Aug 2016 16:44:33 GMT

←Older revision		Revision as of 16:44, 4 August 2016
Line 1:		Line 1:
		+
	==Structure a C. elegans SAS-6 variant==		==Structure a C. elegans SAS-6 variant==
	<StructureSection load='4g79' size='340' side='right' caption='[[4g79]], [[Resolution\|resolution]] 1.80Å' scene=''>		<StructureSection load='4g79' size='340' side='right' caption='[[4g79]], [[Resolution\|resolution]] 1.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4g79]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Caenorhabditis_elegans Caenorhabditis elegans~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4G79 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4G79 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4g79]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Caeel Caeel]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4G79 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4G79 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3pyi\|3pyi]], [[2y3v\|2y3v]], [[2y3w\|2y3w]], [[3q0y\|3q0y]], [[3q0x\|3q0x]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3pyi\|3pyi]], [[2y3v\|2y3v]], [[2y3w\|2y3w]], [[3q0y\|3q0y]], [[3q0x\|3q0x]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">sas-6, Y45F10D.9 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=6239 ~~Caenorhabditis elegans~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">sas-6, Y45F10D.9 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=6239 CAEEL])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4g79 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4g79 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4g79 RCSB], [http://www.ebi.ac.uk/pdbsum/4g79 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4g79 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4g79 OCA], [http://pdbe.org/4g79 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4g79 RCSB], [http://www.ebi.ac.uk/pdbsum/4g79 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4g79 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 18:		Line 19:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 4g79" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Caenorhabditis elegans~~]]	+	[[Category: Caeel]]
	[[Category: Erat, M C]]		[[Category: Erat, M C]]
	[[Category: Vakonakis, I]]		[[Category: Vakonakis, I]]

OCA at 11:05, 25 December 2014

OCA — Thu, 25 Dec 2014 11:05:33 GMT

←Older revision		Revision as of 11:05, 25 December 2014
Line 1:		Line 1:
-	~~{{STRUCTURE_4g79\| PDB~~=4g79 \| ~~SCENE~~= }}	+	==Structure a C. elegans SAS-6 variant==
-	===~~Structure~~ a C. elegans ~~SAS~~-6 ~~variant~~===	+	<StructureSection load='4g79' size='340' side='right' caption='[[4g79]], [[Resolution\|resolution]] 1.80Å' scene=''>
-	~~{{ABSTRACT_PUBMED_23798409}}~~	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[4g79]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Caenorhabditis_elegans Caenorhabditis elegans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4G79 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4G79 FirstGlance]. <br>
-	==Function==	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3pyi\|3pyi]], [[2y3v\|2y3v]], [[2y3w\|2y3w]], [[3q0y\|3q0y]], [[3q0x\|3q0x]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">sas-6, Y45F10D.9 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=6239 Caenorhabditis elegans])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4g79 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4g79 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4g79 RCSB], [http://www.ebi.ac.uk/pdbsum/4g79 PDBsum]</span></td></tr>
		+	</table>
		+	== Function ==
	[[http://www.uniprot.org/uniprot/SAS6_CAEEL SAS6_CAEEL]] Required for centrosome duplication. Participates in centriole assembly.<ref>PMID:15572125</ref> <ref>PMID:15665853</ref>		[[http://www.uniprot.org/uniprot/SAS6_CAEEL SAS6_CAEEL]] Required for centrosome duplication. Participates in centriole assembly.<ref>PMID:15572125</ref> <ref>PMID:15665853</ref>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Centrioles are evolutionary conserved organelles that give rise to cilia and flagella as well as centrosomes. Centrioles display a characteristic ninefold symmetry imposed by the spindle assembly abnormal protein 6 (SAS-6) family. SAS-6 from Chlamydomonas reinhardtii and Danio rerio was shown to form ninefold symmetric, ring-shaped oligomers in vitro that were similar to the cartwheels observed in vivo during early steps of centriole assembly in most species. Here, we report crystallographic and EM analyses showing that, instead, Caenorhabotis elegans SAS-6 self-assembles into a spiral arrangement. Remarkably, we find that this spiral arrangement is also consistent with ninefold symmetry, suggesting that two distinct SAS-6 oligomerization architectures can direct the same output symmetry. Sequence analysis suggests that SAS-6 spirals are restricted to specific nematodes. This oligomeric arrangement may provide a structural basis for the presence of a central tube instead of a cartwheel during centriole assembly in these species.

-	~~==About this Structure==~~	+	Caenorhabditis elegans centriolar protein SAS-6 forms a spiral that is consistent with imparting a ninefold symmetry.,Hilbert M, Erat MC, Hachet V, Guichard P, Blank ID, Fluckiger I, Slater L, Lowe ED, Hatzopoulos GN, Steinmetz MO, Gonczy P, Vakonakis I Proc Natl Acad Sci U S A. 2013 Jul 9;110(28):11373-8. doi:, 10.1073/pnas.1302721110. Epub 2013 Jun 24. PMID:23798409<ref>PMID:23798409</ref>
-	~~[[4g79]]~~ is a ~~1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Caenorhabditis_elegans Caenorhabditis elegans]~~. ~~Full crystallographic information is available from [http~~:/~~/oca~~.~~weizmann~~.ac.il/~~oca-bin/ocashort?id=4G79 OCA].~~	+

-	==~~Reference~~==	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	~~<ref group="xtra">PMID:023798409</ref>~~<references ~~group="xtra"~~/><~~references~~/>	+	</div>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
	[[Category: Caenorhabditis elegans]]		[[Category: Caenorhabditis elegans]]
-	[[Category: Erat, M C.]]	+	[[Category: Erat, M C]]
-	[[Category: Vakonakis, I.]]	+	[[Category: Vakonakis, I]]
	[[Category: Alpha-beta protein]]		[[Category: Alpha-beta protein]]
	[[Category: Beta-sandwich]]		[[Category: Beta-sandwich]]

OCA at 04:35, 18 July 2013

OCA — Thu, 18 Jul 2013 04:35:31 GMT

←Older revision		Revision as of 04:35, 18 July 2013
Line 1:		Line 1:
	{{STRUCTURE_4g79\| PDB=4g79 \| SCENE= }}		{{STRUCTURE_4g79\| PDB=4g79 \| SCENE= }}
	===Structure a C. elegans SAS-6 variant===		===Structure a C. elegans SAS-6 variant===
		+	{{ABSTRACT_PUBMED_23798409}}

	==Function==		==Function==
Line 9:		Line 10:

	==Reference==		==Reference==
-	<references group="xtra"/><references/>	+	<ref group="xtra">PMID:023798409</ref><references group="xtra"/><references/>
	[[Category: Caenorhabditis elegans]]		[[Category: Caenorhabditis elegans]]
	[[Category: Erat, M C.]]		[[Category: Erat, M C.]]

OCA at 07:22, 20 June 2013

OCA — Thu, 20 Jun 2013 07:22:34 GMT

←Older revision		Revision as of 07:22, 20 June 2013
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	{{STRUCTURE_4g79\| PDB=4g79 \| SCENE= }}
		+	===Structure a C. elegans SAS-6 variant===

-	~~The entry 4g79 is ON HOLD~~ ~~until Paper Publication~~	+	==Function==
		+	[[http://www.uniprot.org/uniprot/SAS6_CAEEL SAS6_CAEEL]] Required for centrosome duplication. Participates in centriole assembly.<ref>PMID:15572125</ref> <ref>PMID:15665853</ref>

-	~~Authors~~: ~~Erat, M~~.C.~~, Vakonakis, I~~.	+	==About this Structure==
		+	[[4g79]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Caenorhabditis_elegans Caenorhabditis elegans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4G79 OCA].

-	~~Description~~: ~~Structure a~~ C. ~~elegans SAS~~-~~6 variant~~	+	==Reference==
		+	<references group="xtra"/><references/>
		+	[[Category: Caenorhabditis elegans]]
		+	[[Category: Erat, M C.]]
		+	[[Category: Vakonakis, I.]]
		+	[[Category: Alpha-beta protein]]
		+	[[Category: Beta-sandwich]]
		+	[[Category: Central tube]]
		+	[[Category: Centriolar]]
		+	[[Category: Centriole]]
		+	[[Category: Cytoplasmic]]
		+	[[Category: Structural protein]]

OCA at 05:22, 15 August 2012

OCA — Wed, 15 Aug 2012 05:22:50 GMT

←Older revision		Revision as of 05:22, 15 August 2012
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 4g79 is ON HOLD	+	The entry 4g79 is ON HOLD until Paper Publication

	Authors: Erat, M.C., Vakonakis, I.		Authors: Erat, M.C., Vakonakis, I.

	Description: Structure a C. elegans SAS-6 variant		Description: Structure a C. elegans SAS-6 variant

OCA at 04:58, 8 August 2012

OCA — Wed, 08 Aug 2012 04:58:15 GMT

←Older revision		Revision as of 04:58, 8 August 2012
Line 3:		Line 3:
	The entry 4g79 is ON HOLD		The entry 4g79 is ON HOLD

-	Authors: Erat, M. C., Vakonakis, I.	+	Authors: Erat, M.C., Vakonakis, I.

	Description: Structure a C. elegans SAS-6 variant		Description: Structure a C. elegans SAS-6 variant

OCA: Protected "4g79" [edit=sysop:move=sysop]

OCA — Wed, 01 Aug 2012 05:29:26 GMT

Protected "4g79" [edit=sysop:move=sysop]

←Older revision

Revision as of 05:29, 1 August 2012

OCA: New page: '''Unreleased structure''' The entry 4g79 is ON HOLD Authors: Erat, M. C., Vakonakis, I. Description: Structure a C. elegans SAS-6 variant

OCA — Wed, 01 Aug 2012 05:29:25 GMT

New page: '''Unreleased structure''' The entry 4g79 is ON HOLD Authors: Erat, M. C., Vakonakis, I. Description: Structure a C. elegans SAS-6 variant

New page

'''Unreleased structure'''

The entry 4g79 is ON HOLD

Authors: Erat, M. C., Vakonakis, I.

Description: Structure a C. elegans SAS-6 variant