4gaz - Revision history

OCA at 06:45, 26 October 2022

OCA — Wed, 26 Oct 2022 06:45:55 GMT

←Older revision		Revision as of 06:45, 26 October 2022
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	==Crystal Structure of a Jumonji Domain-containing Protein JMJD5==		==Crystal Structure of a Jumonji Domain-containing Protein JMJD5==
-	<StructureSection load='4gaz' size='340' side='right' caption='[[4gaz]], [[Resolution\|resolution]] 2.81Å' scene=''>	+	<StructureSection load='4gaz' size='340' side='right'caption='[[4gaz]], [[Resolution\|resolution]] 2.81Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4gaz]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Human Human~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GAZ OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4GAZ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4gaz]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GAZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4GAZ FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene>, <scene name='pdbligand=OGA:N-OXALYLGLYCINE'>OGA</scene~~></td></tr>~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene>, <scene name='pdbligand=OGA:N-OXALYLGLYCINE'>OGA</scene></td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3uyj\|3uyj]], [[4aap\|4aap]]</td></tr>~~	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4gaz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gaz OCA], [https://pdbe.org/4gaz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4gaz RCSB], [https://www.ebi.ac.uk/pdbsum/4gaz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4gaz ProSAT]</span></td></tr>
-	~~<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">JMJD5, KDM8 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>~~	+
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/[Histone_H3]-lysine-36_demethylase [Histone H3]-lysine-36 demethylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.11.27 1.14.11.27] </span></td></tr>	+
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4gaz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gaz OCA], [~~http~~://pdbe.org/4gaz PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4gaz RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4gaz PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4gaz ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/KDM8_HUMAN KDM8_HUMAN]] Histone demethylase required for G2/M phase cell cycle progression. Specifically demethylates dimethylated 'Lys-36' (H3K36me2) of histone H3, an epigenetic repressive mark, thereby acting as a transcription activator. Regulates expression of CCNA1 (cyclin-A1), leading to regulate cancer cell proliferation.	+	[https://www.uniprot.org/uniprot/KDM8_HUMAN KDM8_HUMAN] Histone demethylase required for G2/M phase cell cycle progression. Specifically demethylates dimethylated 'Lys-36' (H3K36me2) of histone H3, an epigenetic repressive mark, thereby acting as a transcription activator. Regulates expression of CCNA1 (cyclin-A1), leading to regulate cancer cell proliferation.

	==See Also==		==See Also==
-	*[[Jumonji domain-containing protein\|Jumonji domain-containing protein]]	+	*[[Jumonji domain-containing protein 3D structures\|Jumonji domain-containing protein 3D structures]]
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Human~~]]	+	[[Category: Homo sapiens]]
-	[[Category: Chen, N]]	+	[[Category: Large Structures]]
-	[[Category: Tao, Y]]	+	[[Category: Chen N]]
-	[[Category: Wang, H]]	+	[[Category: Tao Y]]
-	[[Category: Zang, J]]	+	[[Category: Wang H]]
-	[[Category: Zhang, X]]	+	[[Category: Zang J]]
-	[[Category: Zhou, X]]	+	[[Category: Zhang X]]
-	~~[[Category: Demethylase]]~~	+	[[Category: Zhou X]]
-	~~[[Category: Jmjc domain]]~~	+
-	~~[[Category: Oxidoreductase~~]]	+

OCA at 15:09, 4 August 2016

OCA — Thu, 04 Aug 2016 15:09:29 GMT

←Older revision		Revision as of 15:09, 4 August 2016
Line 1:		Line 1:
		+
	==Crystal Structure of a Jumonji Domain-containing Protein JMJD5==		==Crystal Structure of a Jumonji Domain-containing Protein JMJD5==
	<StructureSection load='4gaz' size='340' side='right' caption='[[4gaz]], [[Resolution\|resolution]] 2.81Å' scene=''>		<StructureSection load='4gaz' size='340' side='right' caption='[[4gaz]], [[Resolution\|resolution]] 2.81Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4gaz]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Homo_sapiens Homo sapiens~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GAZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4GAZ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4gaz]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GAZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4GAZ FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene>, <scene name='pdbligand=OGA:N-OXALYLGLYCINE'>OGA</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene>, <scene name='pdbligand=OGA:N-OXALYLGLYCINE'>OGA</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3uyj\|3uyj]], [[4aap\|4aap]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3uyj\|3uyj]], [[4aap\|4aap]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">JMJD5, KDM8 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 ~~Homo sapiens~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">JMJD5, KDM8 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/[Histone_H3]-lysine-36_demethylase [Histone H3]-lysine-36 demethylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.11.27 1.14.11.27] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/[Histone_H3]-lysine-36_demethylase [Histone H3]-lysine-36 demethylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.11.27 1.14.11.27] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4gaz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gaz OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4gaz RCSB], [http://www.ebi.ac.uk/pdbsum/4gaz PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4gaz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gaz OCA], [http://pdbe.org/4gaz PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4gaz RCSB], [http://www.ebi.ac.uk/pdbsum/4gaz PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4gaz ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/KDM8_HUMAN KDM8_HUMAN]] Histone demethylase required for G2/M phase cell cycle progression. Specifically demethylates dimethylated 'Lys-36' (H3K36me2) of histone H3, an epigenetic repressive mark, thereby acting as a transcription activator. Regulates expression of CCNA1 (cyclin-A1), leading to regulate cancer cell proliferation.
		+
		+	==See Also==
		+	*[[Jumonji domain-containing protein\|Jumonji domain-containing protein]]
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Homo sapiens~~]]	+	[[Category: Human]]
	[[Category: Chen, N]]		[[Category: Chen, N]]
	[[Category: Tao, Y]]		[[Category: Tao, Y]]

OCA at 11:22, 21 December 2014

OCA — Sun, 21 Dec 2014 11:22:47 GMT

←Older revision		Revision as of 11:22, 21 December 2014
Line 1:		Line 1:
-	~~{{STRUCTURE_4gaz\| PDB=4gaz \| SCENE= }}~~	+	==Crystal Structure of a Jumonji Domain-containing Protein JMJD5==
-	===Crystal Structure of a Jumonji Domain-containing Protein JMJD5===	+	<StructureSection load='4gaz' size='340' side='right' caption='[[4gaz]], [[Resolution\|resolution]] 2.81Å' scene=''>
-		+	== Structural highlights ==
-	==~~About this Structure~~==	+	<table><tr><td colspan='2'>[[4gaz]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GAZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4GAZ FirstGlance]. <br>
-	[[4gaz]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GAZ OCA].	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene>, <scene name='pdbligand=OGA:N-OXALYLGLYCINE'>OGA</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3uyj\|3uyj]], [[4aap\|4aap]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">JMJD5, KDM8 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
		+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/[Histone_H3]-lysine-36_demethylase [Histone H3]-lysine-36 demethylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.11.27 1.14.11.27] </span></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4gaz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gaz OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4gaz RCSB], [http://www.ebi.ac.uk/pdbsum/4gaz PDBsum]</span></td></tr>
		+	</table>
		+	__TOC__
		+	</StructureSection>
	[[Category: Homo sapiens]]		[[Category: Homo sapiens]]
-	[[Category: Chen, N.]]	+	[[Category: Chen, N]]
-	[[Category: Tao, Y.]]	+	[[Category: Tao, Y]]
-	[[Category: Wang, H.]]	+	[[Category: Wang, H]]
-	[[Category: Zang, J.]]	+	[[Category: Zang, J]]
-	[[Category: Zhang, X.]]	+	[[Category: Zhang, X]]
-	[[Category: Zhou, X.]]	+	[[Category: Zhou, X]]
	[[Category: Demethylase]]		[[Category: Demethylase]]
	[[Category: Jmjc domain]]		[[Category: Jmjc domain]]
	[[Category: Oxidoreductase]]		[[Category: Oxidoreductase]]

OCA at 07:58, 14 August 2013

OCA — Wed, 14 Aug 2013 07:58:35 GMT

←Older revision		Revision as of 07:58, 14 August 2013
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	{{STRUCTURE_4gaz\| PDB=4gaz \| SCENE= }}
		+	===Crystal Structure of a Jumonji Domain-containing Protein JMJD5===

-	~~The entry~~ 4gaz is ~~ON HOLD until Paper Publication~~	+	==About this Structure==
-		+	[[4gaz]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GAZ OCA].
-	~~Authors~~: ~~Wang, H~~.~~, Zhou, X~~.~~, Zhang, X~~., Tao, Y., ~~Chen, N~~., Zang, J.	+	[[Category: Homo sapiens]]
-		+	[[Category: Chen, N.]]
-	~~Description~~: ~~Crystal Structure of a Jumonji Domain-containing Protein JMJD5~~	+	[[Category: Tao, Y.]]
		+	[[Category: Wang, H.]]
		+	[[Category: Zang, J.]]
		+	[[Category: Zhang, X.]]
		+	[[Category: Zhou, X.]]
		+	[[Category: Demethylase]]
		+	[[Category: Jmjc domain]]
		+	[[Category: Oxidoreductase]]

OCA at 05:23, 15 August 2012

OCA — Wed, 15 Aug 2012 05:23:51 GMT

←Older revision		Revision as of 05:23, 15 August 2012
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 4gaz is ON HOLD	+	The entry 4gaz is ON HOLD until Paper Publication

	Authors: Wang, H., Zhou, X., Zhang, X., Tao, Y., Chen, N., Zang, J.		Authors: Wang, H., Zhou, X., Zhang, X., Tao, Y., Chen, N., Zang, J.

	Description: Crystal Structure of a Jumonji Domain-containing Protein JMJD5		Description: Crystal Structure of a Jumonji Domain-containing Protein JMJD5

OCA: Protected "4gaz" [edit=sysop:move=sysop]

OCA — Wed, 01 Aug 2012 05:33:15 GMT

Protected "4gaz" [edit=sysop:move=sysop]

←Older revision

Revision as of 05:33, 1 August 2012

OCA: New page: '''Unreleased structure''' The entry 4gaz is ON HOLD Authors: Wang, H., Zhou, X., Zhang, X., Tao, Y., Chen, N., Zang, J. Description: Crystal Structure of a Jumonji Domain-containing P...

OCA — Wed, 01 Aug 2012 05:33:14 GMT

New page: '''Unreleased structure''' The entry 4gaz is ON HOLD Authors: Wang, H., Zhou, X., Zhang, X., Tao, Y., Chen, N., Zang, J. Description: Crystal Structure of a Jumonji Domain-containing P...

New page

'''Unreleased structure'''

The entry 4gaz is ON HOLD

Authors: Wang, H., Zhou, X., Zhang, X., Tao, Y., Chen, N., Zang, J.

Description: Crystal Structure of a Jumonji Domain-containing Protein JMJD5