4gce - Revision history

OCA at 15:43, 14 March 2024

OCA — Thu, 14 Mar 2024 15:43:33 GMT

←Older revision		Revision as of 15:43, 14 March 2024
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4gce]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GCE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4GCE FirstGlance]. <br>		<table><tr><td colspan='2'>[[4gce]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GCE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4GCE FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CPT:CISPLATIN'>CPT</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.9Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CPT:CISPLATIN'>CPT</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4gce FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gce OCA], [https://pdbe.org/4gce PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4gce RCSB], [https://www.ebi.ac.uk/pdbsum/4gce PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4gce ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4gce FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gce OCA], [https://pdbe.org/4gce PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4gce RCSB], [https://www.ebi.ac.uk/pdbsum/4gce PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4gce ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[https://www.uniprot.org/uniprot/LYSC_CHICK LYSC_CHICK] Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. Has bacteriolytic activity against M.luteus.<ref>PMID:22044478</ref>		[https://www.uniprot.org/uniprot/LYSC_CHICK LYSC_CHICK] Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. Has bacteriolytic activity against M.luteus.<ref>PMID:22044478</ref>
-	<div style="background-color:#fffaf0;">
-	== Publication Abstract from PubMed ==
-	The anticancer agents cisplatin and carboplatin bind to histidine in a protein. This crystal structure study at data-collection temperatures of 100 and 300 K examines their relative binding affinities to a histidine side chain and the effect of a high X-ray radiation dose of up to approximately 1.8 MGy on the stability of the subsequent protein-Pt adducts. Cisplatin binding is visible at the histidine residue, but carboplatin binding is not. Five refined X-ray crystal structures are presented: one at 100 K as a reference and four at 300 K. The diffraction resolutions are 1.8, 2.0, 2.8, 2.9 and 3.5 A.
-
-	The crystal structure analysis of the relative binding of cisplatin and carboplatin in a mixture with histidine in a protein studied at 100 and 300 K with repeated X-ray irradiation.,Helliwell JR, Tanley SW Acta Crystallogr D Biol Crystallogr. 2013 Jan;69(Pt 1):121-5. doi:, 10.1107/S090744491204423X. Epub 2012 Dec 20. PMID:23275170<ref>PMID:23275170</ref>
-
-	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	</div>
-	<div class="pdbe-citations 4gce" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==

OCA at 06:47, 26 October 2022

OCA — Wed, 26 Oct 2022 06:47:57 GMT

←Older revision		Revision as of 06:47, 26 October 2022
Line 3:		Line 3:
	<StructureSection load='4gce' size='340' side='right'caption='[[4gce]], [[Resolution\|resolution]] 2.90Å' scene=''>		<StructureSection load='4gce' size='340' side='right'caption='[[4gce]], [[Resolution\|resolution]] 2.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4gce]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GCE OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4GCE FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4gce]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GCE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4GCE FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CPT:CISPLATIN'>CPT</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene~~></td></tr>~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CPT:CISPLATIN'>CPT</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4dd0\|4dd0]], [[4dd1\|4dd1]], [[4dd2\|4dd2]], [[4dd3\|4dd3]], [[4dd4\|4dd4]], [[4dd6\|4dd6]], [[4dd7\|4dd7]], [[4dd9\|4dd9]], [[4dda\|4dda]], [[4ddb\|4ddb]], [[4ddc\|4ddc]], [[4g49\|4g49]], [[4g4a\|4g4a]], [[4g4b\|4g4b]], [[4g4c\|4g4c]], [[4g4h\|4g4h]], [[4gcb\|4gcb]], [[4gcc\|4gcc]], [[4gcd\|4gcd]], [[4gcf\|4gcf]], [[4gcj\|4gcj]]</td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4gce FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gce OCA], [https://pdbe.org/4gce PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4gce RCSB], [https://www.ebi.ac.uk/pdbsum/4gce PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4gce ProSAT]</span></td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] </span></td></tr>	+
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4gce FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gce OCA], [~~http~~://pdbe.org/4gce PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4gce RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4gce PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4gce ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/LYSC_CHICK LYSC_CHICK]] Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. Has bacteriolytic activity against M.luteus.<ref>PMID:22044478</ref>	+	[https://www.uniprot.org/uniprot/LYSC_CHICK LYSC_CHICK] Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. Has bacteriolytic activity against M.luteus.<ref>PMID:22044478</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 29:		Line 27:
	[[Category: Gallus gallus]]		[[Category: Gallus gallus]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	~~[[Category: Lysozyme]]~~	+	[[Category: Helliwell JR]]
-	[[Category: Helliwell~~, J R~~]]	+	[[Category: Tanley SWM]]
-	[[Category: Tanley~~, S W.M]]~~	+
-	~~[[Category: Binding occupancy]]~~	+
-	~~[[Category: Carboplatin]]~~	+
-	~~[[Category: Cisplatin]]~~	+
-	~~[[Category: Histidine]]~~	+
-	~~[[Category: Hydrolase]]~~	+
-	~~[[Category: Radiation therapy]]~~	+
-	~~[[Category: Relative toxicity]]~~	+
-	~~[[Category: Temperature variation and structure]]~~	+
-	~~[[Category: X-ray radiation damage~~]]	+

OCA at 07:37, 27 March 2019

OCA — Wed, 27 Mar 2019 07:37:45 GMT

←Older revision		Revision as of 07:37, 27 March 2019
Line 1:		Line 1:

	==Room temperature X-ray diffraction study of a 6-fold molar excess of a cisplatin/carboplatin mixture binding to HEWL, Dataset 3==		==Room temperature X-ray diffraction study of a 6-fold molar excess of a cisplatin/carboplatin mixture binding to HEWL, Dataset 3==
-	<StructureSection load='4gce' size='340' side='right' caption='[[4gce]], [[Resolution\|resolution]] 2.90Å' scene=''>	+	<StructureSection load='4gce' size='340' side='right'caption='[[4gce]], [[Resolution\|resolution]] 2.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4gce]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Chick Chick~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GCE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4GCE FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4gce]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GCE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4GCE FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CPT:CISPLATIN'>CPT</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CPT:CISPLATIN'>CPT</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4dd0\|4dd0]], [[4dd1\|4dd1]], [[4dd2\|4dd2]], [[4dd3\|4dd3]], [[4dd4\|4dd4]], [[4dd6\|4dd6]], [[4dd7\|4dd7]], [[4dd9\|4dd9]], [[4dda\|4dda]], [[4ddb\|4ddb]], [[4ddc\|4ddc]], [[4g49\|4g49]], [[4g4a\|4g4a]], [[4g4b\|4g4b]], [[4g4c\|4g4c]], [[4g4h\|4g4h]], [[4gcb\|4gcb]], [[4gcc\|4gcc]], [[4gcd\|4gcd]], [[4gcf\|4gcf]], [[4gcj\|4gcj]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4dd0\|4dd0]], [[4dd1\|4dd1]], [[4dd2\|4dd2]], [[4dd3\|4dd3]], [[4dd4\|4dd4]], [[4dd6\|4dd6]], [[4dd7\|4dd7]], [[4dd9\|4dd9]], [[4dda\|4dda]], [[4ddb\|4ddb]], [[4ddc\|4ddc]], [[4g49\|4g49]], [[4g4a\|4g4a]], [[4g4b\|4g4b]], [[4g4c\|4g4c]], [[4g4h\|4g4h]], [[4gcb\|4gcb]], [[4gcc\|4gcc]], [[4gcd\|4gcd]], [[4gcf\|4gcf]], [[4gcj\|4gcj]]</td></tr>
Line 27:		Line 27:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Chick~~]]	+	[[Category: Gallus gallus]]
		+	[[Category: Large Structures]]
	[[Category: Lysozyme]]		[[Category: Lysozyme]]
	[[Category: Helliwell, J R]]		[[Category: Helliwell, J R]]

OCA at 23:01, 4 August 2016

OCA — Thu, 04 Aug 2016 23:01:45 GMT

←Older revision		Revision as of 23:01, 4 August 2016
Line 1:		Line 1:
		+
	==Room temperature X-ray diffraction study of a 6-fold molar excess of a cisplatin/carboplatin mixture binding to HEWL, Dataset 3==		==Room temperature X-ray diffraction study of a 6-fold molar excess of a cisplatin/carboplatin mixture binding to HEWL, Dataset 3==
	<StructureSection load='4gce' size='340' side='right' caption='[[4gce]], [[Resolution\|resolution]] 2.90Å' scene=''>		<StructureSection load='4gce' size='340' side='right' caption='[[4gce]], [[Resolution\|resolution]] 2.90Å' scene=''>
Line 6:		Line 7:
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4dd0\|4dd0]], [[4dd1\|4dd1]], [[4dd2\|4dd2]], [[4dd3\|4dd3]], [[4dd4\|4dd4]], [[4dd6\|4dd6]], [[4dd7\|4dd7]], [[4dd9\|4dd9]], [[4dda\|4dda]], [[4ddb\|4ddb]], [[4ddc\|4ddc]], [[4g49\|4g49]], [[4g4a\|4g4a]], [[4g4b\|4g4b]], [[4g4c\|4g4c]], [[4g4h\|4g4h]], [[4gcb\|4gcb]], [[4gcc\|4gcc]], [[4gcd\|4gcd]], [[4gcf\|4gcf]], [[4gcj\|4gcj]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4dd0\|4dd0]], [[4dd1\|4dd1]], [[4dd2\|4dd2]], [[4dd3\|4dd3]], [[4dd4\|4dd4]], [[4dd6\|4dd6]], [[4dd7\|4dd7]], [[4dd9\|4dd9]], [[4dda\|4dda]], [[4ddb\|4ddb]], [[4ddc\|4ddc]], [[4g49\|4g49]], [[4g4a\|4g4a]], [[4g4b\|4g4b]], [[4g4c\|4g4c]], [[4g4h\|4g4h]], [[4gcb\|4gcb]], [[4gcc\|4gcc]], [[4gcd\|4gcd]], [[4gcf\|4gcf]], [[4gcj\|4gcj]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4gce FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gce OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4gce RCSB], [http://www.ebi.ac.uk/pdbsum/4gce PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4gce FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gce OCA], [http://pdbe.org/4gce PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4gce RCSB], [http://www.ebi.ac.uk/pdbsum/4gce PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4gce ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 18:		Line 19:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 4gce" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==

OCA at 13:49, 25 December 2014

OCA — Thu, 25 Dec 2014 13:49:23 GMT

←Older revision		Revision as of 13:49, 25 December 2014
Line 1:		Line 1:
-	[[~~Image:~~4gce.~~png~~\|~~left~~\|~~200px~~]]	+	==Room temperature X-ray diffraction study of a 6-fold molar excess of a cisplatin/carboplatin mixture binding to HEWL, Dataset 3==
		+	<StructureSection load='4gce' size='340' side='right' caption='[[4gce]], [[Resolution\|resolution]] 2.90Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[4gce]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Chick Chick]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GCE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4GCE FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CPT:CISPLATIN'>CPT</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4dd0\|4dd0]], [[4dd1\|4dd1]], [[4dd2\|4dd2]], [[4dd3\|4dd3]], [[4dd4\|4dd4]], [[4dd6\|4dd6]], [[4dd7\|4dd7]], [[4dd9\|4dd9]], [[4dda\|4dda]], [[4ddb\|4ddb]], [[4ddc\|4ddc]], [[4g49\|4g49]], [[4g4a\|4g4a]], [[4g4b\|4g4b]], [[4g4c\|4g4c]], [[4g4h\|4g4h]], [[4gcb\|4gcb]], [[4gcc\|4gcc]], [[4gcd\|4gcd]], [[4gcf\|4gcf]], [[4gcj\|4gcj]]</td></tr>
		+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] </span></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4gce FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gce OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4gce RCSB], [http://www.ebi.ac.uk/pdbsum/4gce PDBsum]</span></td></tr>
		+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/LYSC_CHICK LYSC_CHICK]] Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. Has bacteriolytic activity against M.luteus.<ref>PMID:22044478</ref>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The anticancer agents cisplatin and carboplatin bind to histidine in a protein. This crystal structure study at data-collection temperatures of 100 and 300 K examines their relative binding affinities to a histidine side chain and the effect of a high X-ray radiation dose of up to approximately 1.8 MGy on the stability of the subsequent protein-Pt adducts. Cisplatin binding is visible at the histidine residue, but carboplatin binding is not. Five refined X-ray crystal structures are presented: one at 100 K as a reference and four at 300 K. The diffraction resolutions are 1.8, 2.0, 2.8, 2.9 and 3.5 A.

-	~~{{STRUCTURE_4gce\| PDB=4gce \| SCENE= }}~~	+	The crystal structure analysis of the relative binding of cisplatin and carboplatin in a mixture with histidine in a protein studied at 100 and 300 K with repeated X-ray irradiation.,Helliwell JR, Tanley SW Acta Crystallogr D Biol Crystallogr. 2013 Jan;69(Pt 1):121-5. doi:, 10.1107/S090744491204423X. Epub 2012 Dec 20. PMID:23275170<ref>PMID:23275170</ref>

-	~~===Room temperature X-ray diffraction study of~~ a ~~6-fold molar excess~~ of ~~a cisplatin~~/~~carboplatin mixture binding to HEWL, Dataset 3===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>

-	~~{{ABSTRACT_PUBMED_23275170}}~~	+	==See Also==
-		+	*[[Lysozyme 3D structures\|Lysozyme 3D structures]]
-	==~~About this Structure~~==	+	== References ==
-	[[~~4gce~~]] ~~is a 1 chain structure with sequence from [http:~~//~~en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GCE OCA].~~	+	<references/>
-	[[Category: ~~Gallus gallus~~]]	+	__TOC__
		+	</StructureSection>
		+	[[Category: Chick]]
	[[Category: Lysozyme]]		[[Category: Lysozyme]]
-	[[Category: Helliwell, J R.]]	+	[[Category: Helliwell, J R]]
-	[[Category: Tanley, S W.M.]]	+	[[Category: Tanley, S W.M]]
	[[Category: Binding occupancy]]		[[Category: Binding occupancy]]
	[[Category: Carboplatin]]		[[Category: Carboplatin]]

OCA at 11:44, 23 January 2013

OCA — Wed, 23 Jan 2013 11:44:20 GMT

←Older revision		Revision as of 11:44, 23 January 2013
Line 1:		Line 1:
-	[[Image:4gce.~~jpg~~\|left\|200px]]	+	[[Image:4gce.png\|left\|200px]]

	{{STRUCTURE_4gce\| PDB=4gce \| SCENE= }}		{{STRUCTURE_4gce\| PDB=4gce \| SCENE= }}
Line 5:		Line 5:
	===Room temperature X-ray diffraction study of a 6-fold molar excess of a cisplatin/carboplatin mixture binding to HEWL, Dataset 3===		===Room temperature X-ray diffraction study of a 6-fold molar excess of a cisplatin/carboplatin mixture binding to HEWL, Dataset 3===

		+	{{ABSTRACT_PUBMED_23275170}}

	==About this Structure==		==About this Structure==

OCA at 09:36, 2 January 2013

OCA — Wed, 02 Jan 2013 09:36:23 GMT

←Older revision		Revision as of 09:36, 2 January 2013
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	[[Image:4gce.jpg\|left\|200px]]

-	~~The entry~~ 4gce ~~is ON HOLD~~ ~~until Paper Publication~~	+	{{STRUCTURE_4gce\| PDB=4gce \| SCENE= }}

-	~~Authors: Helliwell~~, ~~J.R., Tanley, S.W.M.~~	+	===Room temperature X-ray diffraction study of a 6-fold molar excess of a cisplatin/carboplatin mixture binding to HEWL, Dataset 3===

-	~~Description~~: ~~Room temperature X~~-~~ray diffraction study of a 6-fold molar excess of a cisplatin~~/~~carboplatin mixture binding to HEWL~~, ~~Dataset 3~~	+
		+	==About this Structure==
		+	[[4gce]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GCE OCA].
		+	[[Category: Gallus gallus]]
		+	[[Category: Lysozyme]]
		+	[[Category: Helliwell, J R.]]
		+	[[Category: Tanley, S W.M.]]
		+	[[Category: Binding occupancy]]
		+	[[Category: Carboplatin]]
		+	[[Category: Cisplatin]]
		+	[[Category: Histidine]]
		+	[[Category: Hydrolase]]
		+	[[Category: Radiation therapy]]
		+	[[Category: Relative toxicity]]
		+	[[Category: Temperature variation and structure]]
		+	[[Category: X-ray radiation damage]]

OCA at 05:32, 22 August 2012

OCA — Wed, 22 Aug 2012 05:32:57 GMT

←Older revision		Revision as of 05:32, 22 August 2012
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 4gce is ON HOLD	+	The entry 4gce is ON HOLD until Paper Publication

	Authors: Helliwell, J.R., Tanley, S.W.M.		Authors: Helliwell, J.R., Tanley, S.W.M.

	Description: Room temperature X-ray diffraction study of a 6-fold molar excess of a cisplatin/carboplatin mixture binding to HEWL, Dataset 3		Description: Room temperature X-ray diffraction study of a 6-fold molar excess of a cisplatin/carboplatin mixture binding to HEWL, Dataset 3

OCA at 05:24, 15 August 2012

OCA — Wed, 15 Aug 2012 05:24:08 GMT

←Older revision		Revision as of 05:24, 15 August 2012
Line 3:		Line 3:
	The entry 4gce is ON HOLD		The entry 4gce is ON HOLD

-	Authors: Helliwell, J.R., Tanley, S.WM.	+	Authors: Helliwell, J.R., Tanley, S.W.M.

-	Description: Room temperature X-ray diffraction study of a 6-fold molar excess of a cisplatin/carboplatin mixture binding to HEWL. Dataset 3	+	Description: Room temperature X-ray diffraction study of a 6-fold molar excess of a cisplatin/carboplatin mixture binding to HEWL, Dataset 3

OCA: Protected "4gce" [edit=sysop:move=sysop]

OCA — Wed, 08 Aug 2012 05:00:17 GMT

Protected "4gce" [edit=sysop:move=sysop]

←Older revision

Revision as of 05:00, 8 August 2012