4gnt - Revision history

OCA at 11:33, 1 March 2024

OCA — Fri, 01 Mar 2024 11:33:02 GMT

←Older revision		Revision as of 11:33, 1 March 2024
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4gnt]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GNT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4GNT FirstGlance]. <br>		<table><tr><td colspan='2'>[[4gnt]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GNT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4GNT FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.41Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4gnt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gnt OCA], [https://pdbe.org/4gnt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4gnt RCSB], [https://www.ebi.ac.uk/pdbsum/4gnt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4gnt ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4gnt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gnt OCA], [https://pdbe.org/4gnt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4gnt RCSB], [https://www.ebi.ac.uk/pdbsum/4gnt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4gnt ProSAT]</span></td></tr>
	</table>		</table>

OCA at 07:07, 26 October 2022

OCA — Wed, 26 Oct 2022 07:07:21 GMT

←Older revision		Revision as of 07:07, 26 October 2022
Line 3:		Line 3:
	<StructureSection load='4gnt' size='340' side='right'caption='[[4gnt]], [[Resolution\|resolution]] 2.41Å' scene=''>		<StructureSection load='4gnt' size='340' side='right'caption='[[4gnt]], [[Resolution\|resolution]] 2.41Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4gnt]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Lk3_transgenic_mice Lk3 transgenic mice~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GNT OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4GNT FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4gnt]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GNT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4GNT FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>~~</td></tr>~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	~~<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Ywhab ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])~~</td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4gnt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gnt OCA], [https://pdbe.org/4gnt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4gnt RCSB], [https://www.ebi.ac.uk/pdbsum/4gnt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4gnt ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4gnt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gnt OCA], [~~http~~://pdbe.org/4gnt PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4gnt RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4gnt PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4gnt ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/1433B_MOUSE 1433B_MOUSE]] Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negative regulator of osteogenesis. Blocks the nuclear translocation of the phosphorylated form (by AKT1) of SRPK2 and antagonizes its stimulatory effect on cyclin D1 expression resulting in blockage of neuronal apoptosis elicited by SRPK2 (By similarity)~~. [[http://www.uniprot.org/uniprot/MLXPL_MOUSE MLXPL_MOUSE]] Transcriptional repressor. Binds to the canonical and non-canonical E box sequences 5'-CACGTG-3'~~.	+	[https://www.uniprot.org/uniprot/1433B_MOUSE 1433B_MOUSE] Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negative regulator of osteogenesis. Blocks the nuclear translocation of the phosphorylated form (by AKT1) of SRPK2 and antagonizes its stimulatory effect on cyclin D1 expression resulting in blockage of neuronal apoptosis elicited by SRPK2 (By similarity).

	==See Also==		==See Also==
Line 16:		Line 15:
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Lk3 transgenic mice~~]]	+	[[Category: Mus musculus]]
-	[[Category: Huang, N]]	+	[[Category: Huang N]]
-	[[Category: Zhang, H]]	+	[[Category: Zhang H]]
-	~~[[Category: 14-3-3]]~~	+
-	~~[[Category: Alpha-alpha helical]]~~	+
-	~~[[Category: Cytoplasm/nucleus]]~~	+
-	~~[[Category: Protein binding]]~~	+
-	~~[[Category: Protein-protein complex]]~~	+
-	~~[[Category: Protein-protein interaction~~]]	+

OCA at 11:55, 17 July 2019

OCA — Wed, 17 Jul 2019 11:55:14 GMT

←Older revision		Revision as of 11:55, 17 July 2019
Line 1:		Line 1:

	==Complex of ChREBP and 14-3-3beta==		==Complex of ChREBP and 14-3-3beta==
-	<StructureSection load='4gnt' size='340' side='right' caption='[[4gnt]], [[Resolution\|resolution]] 2.41Å' scene=''>	+	<StructureSection load='4gnt' size='340' side='right'caption='[[4gnt]], [[Resolution\|resolution]] 2.41Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4gnt]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GNT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4GNT FirstGlance]. <br>		<table><tr><td colspan='2'>[[4gnt]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GNT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4GNT FirstGlance]. <br>
Line 12:		Line 12:

	==See Also==		==See Also==
-	*[[14-3-3 protein\|14-3-3 protein]]	+	*[[14-3-3 protein 3D structures\|14-3-3 protein 3D structures]]
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Lk3 transgenic mice]]		[[Category: Lk3 transgenic mice]]
	[[Category: Huang, N]]		[[Category: Huang, N]]

OCA at 04:29, 5 August 2016

OCA — Fri, 05 Aug 2016 04:29:11 GMT

←Older revision		Revision as of 04:29, 5 August 2016
Line 1:		Line 1:
		+
	==Complex of ChREBP and 14-3-3beta==		==Complex of ChREBP and 14-3-3beta==
	<StructureSection load='4gnt' size='340' side='right' caption='[[4gnt]], [[Resolution\|resolution]] 2.41Å' scene=''>		<StructureSection load='4gnt' size='340' side='right' caption='[[4gnt]], [[Resolution\|resolution]] 2.41Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4gnt]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Mus_musculus Mus musculus~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GNT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4GNT FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4gnt]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GNT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4GNT FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Ywhab ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 ~~Mus musculus~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Ywhab ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4gnt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gnt OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4gnt RCSB], [http://www.ebi.ac.uk/pdbsum/4gnt PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4gnt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gnt OCA], [http://pdbe.org/4gnt PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4gnt RCSB], [http://www.ebi.ac.uk/pdbsum/4gnt PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4gnt ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[http://www.uniprot.org/uniprot/MLXPL_MOUSE MLXPL_MOUSE]] Transcriptional repressor. Binds to the canonical and non-canonical E box sequences 5'-CACGTG-3'.	+	[[http://www.uniprot.org/uniprot/1433B_MOUSE 1433B_MOUSE]] Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negative regulator of osteogenesis. Blocks the nuclear translocation of the phosphorylated form (by AKT1) of SRPK2 and antagonizes its stimulatory effect on cyclin D1 expression resulting in blockage of neuronal apoptosis elicited by SRPK2 (By similarity). [[http://www.uniprot.org/uniprot/MLXPL_MOUSE MLXPL_MOUSE]] Transcriptional repressor. Binds to the canonical and non-canonical E box sequences 5'-CACGTG-3'.

	==See Also==		==See Also==
Line 14:		Line 15:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Mus musculus~~]]	+	[[Category: Lk3 transgenic mice]]
	[[Category: Huang, N]]		[[Category: Huang, N]]
	[[Category: Zhang, H]]		[[Category: Zhang, H]]

OCA at 22:58, 24 December 2014

OCA — Wed, 24 Dec 2014 22:58:27 GMT

←Older revision		Revision as of 22:58, 24 December 2014
Line 7:		Line 7:
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4gnt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gnt OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4gnt RCSB], [http://www.ebi.ac.uk/pdbsum/4gnt PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4gnt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gnt OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4gnt RCSB], [http://www.ebi.ac.uk/pdbsum/4gnt PDBsum]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/MLXPL_MOUSE MLXPL_MOUSE]] Transcriptional repressor. Binds to the canonical and non-canonical E box sequences 5'-CACGTG-3'.

	==See Also==		==See Also==

OCA at 09:52, 10 December 2014

OCA — Wed, 10 Dec 2014 09:52:37 GMT

←Older revision		Revision as of 09:52, 10 December 2014
Line 1:		Line 1:
-	[[~~Image:~~4gnt.~~jpg~~\|~~left~~\|~~200px~~]]	+	==Complex of ChREBP and 14-3-3beta==
		+	<StructureSection load='4gnt' size='340' side='right' caption='[[4gnt]], [[Resolution\|resolution]] 2.41Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[4gnt]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GNT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4GNT FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Ywhab ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 Mus musculus])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4gnt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gnt OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4gnt RCSB], [http://www.ebi.ac.uk/pdbsum/4gnt PDBsum]</span></td></tr>
		+	</table>

-	~~{{STRUCTURE_4gnt\| PDB~~=~~4gnt \| SCENE~~= }}	+	==See Also==
-		+	*[[14-3-3 protein\|14-3-3 protein]]
-	==~~=Complex of ChREBP and~~ 14-3-~~3beta===~~	+	__TOC__
-		+	</StructureSection>
-		+
-	~~==About this Structure==~~	+
-	~~[[4gnt]] is a 2 chain structure with sequence from [http:~~/~~/en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GNT OCA].~~	+
	[[Category: Mus musculus]]		[[Category: Mus musculus]]
-	[[Category: Huang, N.]]	+	[[Category: Huang, N]]
-	[[Category: Zhang, H.]]	+	[[Category: Zhang, H]]
	[[Category: 14-3-3]]		[[Category: 14-3-3]]
	[[Category: Alpha-alpha helical]]		[[Category: Alpha-alpha helical]]

OCA at 07:46, 24 October 2012

OCA — Wed, 24 Oct 2012 07:46:19 GMT

←Older revision		Revision as of 07:46, 24 October 2012
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	[[Image:4gnt.jpg\|left\|200px]]

-	~~The entry~~ 4gnt ~~is ON HOLD~~	+	{{STRUCTURE_4gnt\| PDB=4gnt \| SCENE= }}

-	~~Authors: Zhang, H., Huang, N.~~	+	===Complex of ChREBP and 14-3-3beta===

-	~~Description~~: ~~Complex of ChREBP and~~ 14-3-~~3beta~~	+
		+	==About this Structure==
		+	[[4gnt]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GNT OCA].
		+	[[Category: Mus musculus]]
		+	[[Category: Huang, N.]]
		+	[[Category: Zhang, H.]]
		+	[[Category: 14-3-3]]
		+	[[Category: Alpha-alpha helical]]
		+	[[Category: Cytoplasm/nucleus]]
		+	[[Category: Protein binding]]
		+	[[Category: Protein-protein complex]]
		+	[[Category: Protein-protein interaction]]

OCA: Protected "4gnt" [edit=sysop:move=sysop]

OCA — Wed, 29 Aug 2012 04:48:14 GMT

Protected "4gnt" [edit=sysop:move=sysop]

←Older revision

Revision as of 04:48, 29 August 2012

OCA: New page: '''Unreleased structure''' The entry 4gnt is ON HOLD Authors: Zhang, H., Huang, N. Description: Complex of ChREBP and 14-3-3beta

OCA — Wed, 29 Aug 2012 04:48:13 GMT

New page: '''Unreleased structure''' The entry 4gnt is ON HOLD Authors: Zhang, H., Huang, N. Description: Complex of ChREBP and 14-3-3beta

New page

'''Unreleased structure'''

The entry 4gnt is ON HOLD

Authors: Zhang, H., Huang, N.

Description: Complex of ChREBP and 14-3-3beta