4gop - Revision history

OCA at 07:08, 26 October 2022

OCA — Wed, 26 Oct 2022 07:08:29 GMT

←Older revision		Revision as of 07:08, 26 October 2022
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	==Structure and Conformational Change of a Replication Protein A Heterotrimer Bound to ssDNA==		==Structure and Conformational Change of a Replication Protein A Heterotrimer Bound to ssDNA==
-	<StructureSection load='4gop' size='340' side='right' caption='[[4gop]], [[Resolution\|resolution]] 3.10Å' scene=''>	+	<StructureSection load='4gop' size='340' side='right'caption='[[4gop]], [[Resolution\|resolution]] 3.10Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4gop]] is a 8 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Corn_smut_fungus Corn smut fungus~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GOP OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4GOP FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4gop]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Ustilago_maydis_521 Ustilago maydis 521] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GOP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4GOP FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>~~</td></tr>~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">UM04165.1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=237631 Corn smut fungus]), UM02579.1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=237631 Corn smut fungus]), UM05156.1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=237631 Corn smut fungus])</td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4gop FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gop OCA], [https://pdbe.org/4gop PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4gop RCSB], [https://www.ebi.ac.uk/pdbsum/4gop PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4gop ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4gop FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gop OCA], [~~http~~://pdbe.org/4gop PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4gop RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4gop PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4gop ProSAT]</span></td></tr>	+
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Corn smut fungus~~]]	+	[[Category: Large Structures]]
-	[[Category: ~~Jie, F~~]]	+	[[Category: Synthetic construct]]
-	[[Category: ~~Pavletich, N P~~]]	+	[[Category: Ustilago maydis 521]]
-	[[Category: ~~Dna binding protein-dna complex~~]]	+	[[Category: Jie F]]
-	[[Category: ~~Ob fold]]~~	+	[[Category: Pavletich NP]]
-	~~[[Category: Ssdna binding~~]]	+

OCA at 20:01, 15 December 2016

OCA — Thu, 15 Dec 2016 20:01:21 GMT

←Older revision		Revision as of 20:01, 15 December 2016
Line 1:		Line 1:
		+
	==Structure and Conformational Change of a Replication Protein A Heterotrimer Bound to ssDNA==		==Structure and Conformational Change of a Replication Protein A Heterotrimer Bound to ssDNA==
	<StructureSection load='4gop' size='340' side='right' caption='[[4gop]], [[Resolution\|resolution]] 3.10Å' scene=''>		<StructureSection load='4gop' size='340' side='right' caption='[[4gop]], [[Resolution\|resolution]] 3.10Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4gop]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Ustilago_maydis_521 Ustilago maydis 521~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GOP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4GOP FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4gop]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Corn_smut_fungus Corn smut fungus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GOP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4GOP FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">UM04165.1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=237631 ~~Ustilago maydis 521~~]), UM02579.1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=237631 ~~Ustilago maydis 521~~]), UM05156.1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=237631 ~~Ustilago maydis 521~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">UM04165.1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=237631 Corn smut fungus]), UM02579.1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=237631 Corn smut fungus]), UM05156.1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=237631 Corn smut fungus])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4gop FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gop OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4gop RCSB], [http://www.ebi.ac.uk/pdbsum/4gop PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4gop FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gop OCA], [http://pdbe.org/4gop PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4gop RCSB], [http://www.ebi.ac.uk/pdbsum/4gop PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4gop ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
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	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 4gop" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Ustilago maydis 521~~]]	+	[[Category: Corn smut fungus]]
	[[Category: Jie, F]]		[[Category: Jie, F]]
	[[Category: Pavletich, N P]]		[[Category: Pavletich, N P]]

OCA at 09:37, 10 December 2014

OCA — Wed, 10 Dec 2014 09:37:59 GMT

←Older revision		Revision as of 09:37, 10 December 2014
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-	[[~~Image:~~4gop.~~jpg~~\|~~left~~\|~~200px~~]]	+	==Structure and Conformational Change of a Replication Protein A Heterotrimer Bound to ssDNA==
		+	<StructureSection load='4gop' size='340' side='right' caption='[[4gop]], [[Resolution\|resolution]] 3.10Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[4gop]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Ustilago_maydis_521 Ustilago maydis 521]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GOP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4GOP FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">UM04165.1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=237631 Ustilago maydis 521]), UM02579.1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=237631 Ustilago maydis 521]), UM05156.1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=237631 Ustilago maydis 521])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4gop FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gop OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4gop RCSB], [http://www.ebi.ac.uk/pdbsum/4gop PDBsum]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Replication protein A (RPA) is the main eukaryotic ssDNA-binding protein with essential roles in DNA replication, recombination, and repair. RPA maintains the DNA as single-stranded and also interacts with other DNA-processing proteins, coordinating their assembly and disassembly on DNA. RPA binds to ssDNA in two conformational states with opposing affinities for DNA and proteins. The RPA-protein interactions are compatible with a low DNA affinity state that involves DNA-binding domain A (DBD-A) and DBD-B but not with the high DNA affinity state that additionally engages DBD-C and DBD-D. The structure of the high-affinity RPA-ssDNA complex reported here shows a compact quaternary structure held together by a four-way interface between DBD-B, DBD-C, the intervening linker (BC linker), and ssDNA. The BC linker binds into the DNA-binding groove of DBD-B, mimicking DNA. The associated conformational change and partial occlusion of the DBD-A-DBA-B protein-protein interaction site establish a mechanism for the allosteric coupling of RPA-DNA and RPA-protein interactions.

-	~~{{STRUCTURE_4gop\| PDB=4gop \| SCENE= }}~~	+	Structure and conformational change of a replication protein A heterotrimer bound to ssDNA.,Fan J, Pavletich NP Genes Dev. 2012 Oct 15;26(20):2337-47. doi: 10.1101/gad.194787.112. PMID:23070815<ref>PMID:23070815</ref>

-	~~===Structure and Conformational Change~~ of ~~a Replication Protein A Heterotrimer Bound to ssDNA===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_23070815}}~~	+	== References ==
-		+	<references/>
-	==~~About this Structure~~==	+	__TOC__
-	~~[[4gop]] is a 8 chain structure with sequence from [http:~~//~~en.wikipedia.org/wiki/Ustilago_maydis_521 Ustilago maydis 521]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GOP OCA].~~	+	</StructureSection>
	[[Category: Ustilago maydis 521]]		[[Category: Ustilago maydis 521]]
-	[[Category: Jie, F.]]	+	[[Category: Jie, F]]
-	[[Category: Pavletich, N P.]]	+	[[Category: Pavletich, N P]]
	[[Category: Dna binding protein-dna complex]]		[[Category: Dna binding protein-dna complex]]
	[[Category: Ob fold]]		[[Category: Ob fold]]
	[[Category: Ssdna binding]]		[[Category: Ssdna binding]]

OCA at 14:25, 28 November 2012

OCA — Wed, 28 Nov 2012 14:25:22 GMT

←Older revision		Revision as of 14:25, 28 November 2012
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	[[Image:4gop.jpg\|left\|200px]]

-	~~The entry~~ 4gop ~~is ON HOLD~~ ~~until Paper Publication~~	+	{{STRUCTURE_4gop\| PDB=4gop \| SCENE= }}

-	~~Authors: Pavletich, N.P., Jie, F.~~	+	===Structure and Conformational Change of a Replication Protein A Heterotrimer Bound to ssDNA===

-	~~Description:~~ Structure of	+	{{ABSTRACT_PUBMED_23070815}}
		+
		+	==About this Structure==
		+	[[4gop]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Ustilago_maydis_521 Ustilago maydis 521]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GOP OCA].
		+	[[Category: Ustilago maydis 521]]
		+	[[Category: Jie, F.]]
		+	[[Category: Pavletich, N P.]]
		+	[[Category: Dna binding protein-dna complex]]
		+	[[Category: Ob fold]]
		+	[[Category: Ssdna binding]]

OCA at 07:06, 24 October 2012

OCA — Wed, 24 Oct 2012 07:06:00 GMT

←Older revision		Revision as of 07:06, 24 October 2012
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 4gop is ON HOLD	+	The entry 4gop is ON HOLD until Paper Publication

	Authors: Pavletich, N.P., Jie, F.		Authors: Pavletich, N.P., Jie, F.

	Description: Structure of		Description: Structure of

OCA: Protected "4gop" [edit=sysop:move=sysop]

OCA — Wed, 29 Aug 2012 04:49:07 GMT

Protected "4gop" [edit=sysop:move=sysop]

←Older revision

Revision as of 04:49, 29 August 2012

OCA: New page: '''Unreleased structure''' The entry 4gop is ON HOLD Authors: Pavletich, N.P., Jie, F. Description: Structure of

OCA — Wed, 29 Aug 2012 04:49:06 GMT

New page: '''Unreleased structure''' The entry 4gop is ON HOLD Authors: Pavletich, N.P., Jie, F. Description: Structure of

New page

'''Unreleased structure'''

The entry 4gop is ON HOLD

Authors: Pavletich, N.P., Jie, F.

Description: Structure of