4gsj - Revision history

OCA at 15:55, 14 March 2024

OCA — Thu, 14 Mar 2024 15:55:16 GMT

←Older revision		Revision as of 15:55, 14 March 2024
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4gsj]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GSJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4GSJ FirstGlance]. <br>		<table><tr><td colspan='2'>[[4gsj]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GSJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4GSJ FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=IPA:ISOPROPYL+ALCOHOL'>IPA</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.695Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=IPA:ISOPROPYL+ALCOHOL'>IPA</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4gsj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gsj OCA], [https://pdbe.org/4gsj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4gsj RCSB], [https://www.ebi.ac.uk/pdbsum/4gsj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4gsj ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4gsj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gsj OCA], [https://pdbe.org/4gsj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4gsj RCSB], [https://www.ebi.ac.uk/pdbsum/4gsj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4gsj ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[https://www.uniprot.org/uniprot/ATG7_YEAST ATG7_YEAST] E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 and ATG8 for its conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes.<ref>PMID:9759731</ref> <ref>PMID:8224160</ref> <ref>PMID:7593182</ref> <ref>PMID:10233148</ref> <ref>PMID:10233150</ref> <ref>PMID:11100732</ref> <ref>PMID:11149920</ref> <ref>PMID:12965207</ref> <ref>PMID:15277523</ref>		[https://www.uniprot.org/uniprot/ATG7_YEAST ATG7_YEAST] E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 and ATG8 for its conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes.<ref>PMID:9759731</ref> <ref>PMID:8224160</ref> <ref>PMID:7593182</ref> <ref>PMID:10233148</ref> <ref>PMID:10233150</ref> <ref>PMID:11100732</ref> <ref>PMID:11149920</ref> <ref>PMID:12965207</ref> <ref>PMID:15277523</ref>
-	<div style="background-color:#fffaf0;">
-	== Publication Abstract from PubMed ==
-	Core functions of autophagy are mediated by ubiquitin-like protein (UBL) cascades, in which a homodimeric E1 enzyme, Atg7, directs the UBLs Atg8 and Atg12 to their respective E2 enzymes, Atg3 and Atg10. Crystallographic and mutational analyses of yeast (Atg7-Atg3)(2) and (Atg7-Atg10)(2) complexes reveal noncanonical, multisite E1-E2 recognition in autophagy. Atg7's unique N-terminal domain recruits distinctive elements from the Atg3 and Atg10 'backsides'. This, along with E1 and E2 conformational variability, allows presentation of 'frontside' Atg3 and Atg10 active sites to the catalytic cysteine in the C-terminal domain from the opposite Atg7 protomer in the homodimer. Despite different modes of binding, the data suggest that common principles underlie conjugation in both noncanonical and canonical UBL cascades, whereby flexibly tethered E1 domains recruit E2s through surfaces remote from their active sites to juxtapose the E1 and E2 catalytic cysteines.
-
-	Noncanonical E2 recruitment by the autophagy E1 revealed by Atg7-Atg3 and Atg7-Atg10 structures.,Kaiser SE, Mao K, Taherbhoy AM, Yu S, Olszewski JL, Duda DM, Kurinov I, Deng A, Fenn TD, Klionsky DJ, Schulman BA Nat Struct Mol Biol. 2012 Nov 11. doi: 10.1038/nsmb.2415. PMID:23142976<ref>PMID:23142976</ref>
-
-	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	</div>
-	<div class="pdbe-citations 4gsj" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==

OCA at 07:15, 26 October 2022

OCA — Wed, 26 Oct 2022 07:15:06 GMT

←Older revision		Revision as of 07:15, 26 October 2022
Line 1:		Line 1:

	==Crystal structure of Atg7 NTD K14A F16A D18A mutant==		==Crystal structure of Atg7 NTD K14A F16A D18A mutant==
-	<StructureSection load='4gsj' size='340' side='right' caption='[[4gsj]], [[Resolution\|resolution]] 1.69Å' scene=''>	+	<StructureSection load='4gsj' size='340' side='right'caption='[[4gsj]], [[Resolution\|resolution]] 1.69Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4gsj]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Baker's_yeast Baker's yeast~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GSJ OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4GSJ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4gsj]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GSJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4GSJ FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=IPA:ISOPROPYL+ALCOHOL'>IPA</scene>~~</td></tr>~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=IPA:ISOPROPYL+ALCOHOL'>IPA</scene></td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4gsk\|4gsk]], [[4gsl\|4gsl]]</td></tr>~~	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4gsj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gsj OCA], [https://pdbe.org/4gsj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4gsj RCSB], [https://www.ebi.ac.uk/pdbsum/4gsj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4gsj ProSAT]</span></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">APG7, ATG7, CVT2, YHR171W ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=559292 Baker's yeast])</td></tr>	+
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4gsj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gsj OCA], [~~http~~://pdbe.org/4gsj PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4gsj RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4gsj PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4gsj ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/ATG7_YEAST ATG7_YEAST]] E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 and ATG8 for its conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes.<ref>PMID:9759731</ref> <ref>PMID:8224160</ref> <ref>PMID:7593182</ref> <ref>PMID:10233148</ref> <ref>PMID:10233150</ref> <ref>PMID:11100732</ref> <ref>PMID:11149920</ref> <ref>PMID:12965207</ref> <ref>PMID:15277523</ref>	+	[https://www.uniprot.org/uniprot/ATG7_YEAST ATG7_YEAST] E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 and ATG8 for its conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes.<ref>PMID:9759731</ref> <ref>PMID:8224160</ref> <ref>PMID:7593182</ref> <ref>PMID:10233148</ref> <ref>PMID:10233150</ref> <ref>PMID:11100732</ref> <ref>PMID:11149920</ref> <ref>PMID:12965207</ref> <ref>PMID:15277523</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 20:		Line 18:
	</div>		</div>
	<div class="pdbe-citations 4gsj" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 4gsj" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Autophagy-related protein 3D structures\|Autophagy-related protein 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Baker's yeast~~]]	+	[[Category: Large Structures]]
-	[[Category: Deng, A]]	+	[[Category: Saccharomyces cerevisiae S288C]]
-	[[Category: Duda~~, D M~~]]	+	[[Category: Deng A]]
-	[[Category: Fenn~~, T D~~]]	+	[[Category: Duda DM]]
-	[[Category: Kaiser~~, S E~~]]	+	[[Category: Fenn TD]]
-	[[Category: Klionsky~~, D J~~]]	+	[[Category: Kaiser SE]]
-	[[Category: Kurinov, I]]	+	[[Category: Klionsky DJ]]
-	[[Category: Mao, K]]	+	[[Category: Kurinov I]]
-	[[Category: Olszewski~~, J L~~]]	+	[[Category: Mao K]]
-	[[Category: Schulman~~, B A~~]]	+	[[Category: Olszewski JL]]
-	[[Category: Taherbhoy~~, A M~~]]	+	[[Category: Schulman BA]]
-	[[Category: Yu, S]]	+	[[Category: Taherbhoy AM]]
-	~~[[Category: Protein transport]]~~	+	[[Category: Yu S]]
-	~~[[Category: Ubiquitin-like protein activation enzyme~~]]	+

OCA at 08:32, 15 November 2017

OCA — Wed, 15 Nov 2017 08:32:20 GMT

←Older revision		Revision as of 08:32, 15 November 2017
Line 20:		Line 20:
	</div>		</div>
	<div class="pdbe-citations 4gsj" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 4gsj" style="background-color:#fffaf0;"></div>
-
-	==See Also==
-	*[[Autophagy-related protein\|Autophagy-related protein]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 23:30, 4 August 2016

OCA — Thu, 04 Aug 2016 23:30:41 GMT

←Older revision		Revision as of 23:30, 4 August 2016
Line 1:		Line 1:
		+
	==Crystal structure of Atg7 NTD K14A F16A D18A mutant==		==Crystal structure of Atg7 NTD K14A F16A D18A mutant==
	<StructureSection load='4gsj' size='340' side='right' caption='[[4gsj]], [[Resolution\|resolution]] 1.69Å' scene=''>		<StructureSection load='4gsj' size='340' side='right' caption='[[4gsj]], [[Resolution\|resolution]] 1.69Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4gsj]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Saccharomyces_cerevisiae_s288c Saccharomyces cerevisiae s288c~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GSJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4GSJ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4gsj]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Baker's_yeast Baker's yeast]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GSJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4GSJ FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=IPA:ISOPROPYL+ALCOHOL'>IPA</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=IPA:ISOPROPYL+ALCOHOL'>IPA</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4gsk\|4gsk]], [[4gsl\|4gsl]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4gsk\|4gsk]], [[4gsl\|4gsl]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">APG7, ATG7, CVT2, YHR171W ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=559292 ~~Saccharomyces cerevisiae S288c~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">APG7, ATG7, CVT2, YHR171W ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=559292 Baker's yeast])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4gsj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gsj OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4gsj RCSB], [http://www.ebi.ac.uk/pdbsum/4gsj PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4gsj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gsj OCA], [http://pdbe.org/4gsj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4gsj RCSB], [http://www.ebi.ac.uk/pdbsum/4gsj PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4gsj ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 18:		Line 19:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 4gsj" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Autophagy-related protein\|Autophagy-related protein]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Saccharomyces cerevisiae s288c~~]]	+	[[Category: Baker's yeast]]
	[[Category: Deng, A]]		[[Category: Deng, A]]
	[[Category: Duda, D M]]		[[Category: Duda, D M]]

OCA at 20:42, 24 December 2014

OCA — Wed, 24 Dec 2014 20:42:47 GMT

←Older revision		Revision as of 20:42, 24 December 2014
Line 1:		Line 1:
-	[[~~Image:~~4gsj.~~png~~\|~~left~~\|~~200px~~]]	+	==Crystal structure of Atg7 NTD K14A F16A D18A mutant==
		+	<StructureSection load='4gsj' size='340' side='right' caption='[[4gsj]], [[Resolution\|resolution]] 1.69Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[4gsj]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_s288c Saccharomyces cerevisiae s288c]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GSJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4GSJ FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=IPA:ISOPROPYL+ALCOHOL'>IPA</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4gsk\|4gsk]], [[4gsl\|4gsl]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">APG7, ATG7, CVT2, YHR171W ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=559292 Saccharomyces cerevisiae S288c])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4gsj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gsj OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4gsj RCSB], [http://www.ebi.ac.uk/pdbsum/4gsj PDBsum]</span></td></tr>
		+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/ATG7_YEAST ATG7_YEAST]] E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 and ATG8 for its conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes.<ref>PMID:9759731</ref> <ref>PMID:8224160</ref> <ref>PMID:7593182</ref> <ref>PMID:10233148</ref> <ref>PMID:10233150</ref> <ref>PMID:11100732</ref> <ref>PMID:11149920</ref> <ref>PMID:12965207</ref> <ref>PMID:15277523</ref>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Core functions of autophagy are mediated by ubiquitin-like protein (UBL) cascades, in which a homodimeric E1 enzyme, Atg7, directs the UBLs Atg8 and Atg12 to their respective E2 enzymes, Atg3 and Atg10. Crystallographic and mutational analyses of yeast (Atg7-Atg3)(2) and (Atg7-Atg10)(2) complexes reveal noncanonical, multisite E1-E2 recognition in autophagy. Atg7's unique N-terminal domain recruits distinctive elements from the Atg3 and Atg10 'backsides'. This, along with E1 and E2 conformational variability, allows presentation of 'frontside' Atg3 and Atg10 active sites to the catalytic cysteine in the C-terminal domain from the opposite Atg7 protomer in the homodimer. Despite different modes of binding, the data suggest that common principles underlie conjugation in both noncanonical and canonical UBL cascades, whereby flexibly tethered E1 domains recruit E2s through surfaces remote from their active sites to juxtapose the E1 and E2 catalytic cysteines.

-	~~{{STRUCTURE_4gsj\| PDB=4gsj \| SCENE= }}~~	+	Noncanonical E2 recruitment by the autophagy E1 revealed by Atg7-Atg3 and Atg7-Atg10 structures.,Kaiser SE, Mao K, Taherbhoy AM, Yu S, Olszewski JL, Duda DM, Kurinov I, Deng A, Fenn TD, Klionsky DJ, Schulman BA Nat Struct Mol Biol. 2012 Nov 11. doi: 10.1038/nsmb.2415. PMID:23142976<ref>PMID:23142976</ref>

-	~~===Crystal structure~~ of ~~Atg7 NTD K14A F16A D18A mutant===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_23142976}}~~	+	== References ==
-		+	<references/>
-	==~~About this Structure~~==	+	__TOC__
-	~~[[4gsj]] is a 1 chain structure with sequence from [http:~~//~~en.wikipedia.org/wiki/Saccharomyces_cerevisiae_s288c Saccharomyces cerevisiae s288c]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GSJ OCA].~~	+	</StructureSection>
	[[Category: Saccharomyces cerevisiae s288c]]		[[Category: Saccharomyces cerevisiae s288c]]
-	[[Category: Deng, A.]]	+	[[Category: Deng, A]]
-	[[Category: Duda, D M.]]	+	[[Category: Duda, D M]]
-	[[Category: Fenn, T D.]]	+	[[Category: Fenn, T D]]
-	[[Category: Kaiser, S E.]]	+	[[Category: Kaiser, S E]]
-	[[Category: Klionsky, D J.]]	+	[[Category: Klionsky, D J]]
-	[[Category: Kurinov, I.]]	+	[[Category: Kurinov, I]]
-	[[Category: Mao, K.]]	+	[[Category: Mao, K]]
-	[[Category: Olszewski, J L.]]	+	[[Category: Olszewski, J L]]
-	[[Category: Schulman, B A.]]	+	[[Category: Schulman, B A]]
-	[[Category: Taherbhoy, A M.]]	+	[[Category: Taherbhoy, A M]]
-	[[Category: Yu, S.]]	+	[[Category: Yu, S]]
	[[Category: Protein transport]]		[[Category: Protein transport]]
	[[Category: Ubiquitin-like protein activation enzyme]]		[[Category: Ubiquitin-like protein activation enzyme]]

OCA at 14:30, 28 November 2012

OCA — Wed, 28 Nov 2012 14:30:54 GMT

←Older revision		Revision as of 14:30, 28 November 2012
Line 1:		Line 1:
-	[[Image:4gsj.~~jpg~~\|left\|200px]]	+	[[Image:4gsj.png\|left\|200px]]

	{{STRUCTURE_4gsj\| PDB=4gsj \| SCENE= }}		{{STRUCTURE_4gsj\| PDB=4gsj \| SCENE= }}
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	===Crystal structure of Atg7 NTD K14A F16A D18A mutant===		===Crystal structure of Atg7 NTD K14A F16A D18A mutant===

		+	{{ABSTRACT_PUBMED_23142976}}

	==About this Structure==		==About this Structure==

OCA at 06:59, 14 November 2012

OCA — Wed, 14 Nov 2012 06:59:01 GMT

←Older revision		Revision as of 06:59, 14 November 2012
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	[[Image:4gsj.jpg\|left\|200px]]

-	~~The entry~~ 4gsj ~~is ON HOLD~~ ~~until Paper Publication~~	+	{{STRUCTURE_4gsj\| PDB=4gsj \| SCENE= }}

-	~~Authors: Kaiser, S.E., Mao, K., Taherbhoy, A.M., Yu, S., Olszewski, J.L., Duda, D.M., Kurinov, I., Deng, A., Fenn, T.D., Klionsky, D.J., Schulman, B.A.~~	+	===Crystal structure of Atg7 NTD K14A F16A D18A mutant===

-	~~Description: Crystal~~ structure ~~of Atg7 NTD K14A F16A D18A mutant~~	+
		+	==About this Structure==
		+	[[4gsj]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_s288c Saccharomyces cerevisiae s288c]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GSJ OCA].
		+	[[Category: Saccharomyces cerevisiae s288c]]
		+	[[Category: Deng, A.]]
		+	[[Category: Duda, D M.]]
		+	[[Category: Fenn, T D.]]
		+	[[Category: Kaiser, S E.]]
		+	[[Category: Klionsky, D J.]]
		+	[[Category: Kurinov, I.]]
		+	[[Category: Mao, K.]]
		+	[[Category: Olszewski, J L.]]
		+	[[Category: Schulman, B A.]]
		+	[[Category: Taherbhoy, A M.]]
		+	[[Category: Yu, S.]]
		+	[[Category: Protein transport]]
		+	[[Category: Ubiquitin-like protein activation enzyme]]

OCA at 06:53, 10 October 2012

OCA — Wed, 10 Oct 2012 06:53:29 GMT

←Older revision		Revision as of 06:53, 10 October 2012
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 4gsj is ON HOLD	+	The entry 4gsj is ON HOLD until Paper Publication

	Authors: Kaiser, S.E., Mao, K., Taherbhoy, A.M., Yu, S., Olszewski, J.L., Duda, D.M., Kurinov, I., Deng, A., Fenn, T.D., Klionsky, D.J., Schulman, B.A.		Authors: Kaiser, S.E., Mao, K., Taherbhoy, A.M., Yu, S., Olszewski, J.L., Duda, D.M., Kurinov, I., Deng, A., Fenn, T.D., Klionsky, D.J., Schulman, B.A.

-	Description: E1	+	Description: Crystal structure of Atg7 NTD K14A F16A D18A mutant

OCA: Protected "4gsj" [edit=sysop:move=sysop]

OCA — Wed, 05 Sep 2012 04:57:55 GMT

Protected "4gsj" [edit=sysop:move=sysop]

←Older revision

Revision as of 04:57, 5 September 2012

OCA: New page: '''Unreleased structure''' The entry 4gsj is ON HOLD Authors: Kaiser, S.E., Mao, K., Taherbhoy, A.M., Yu, S., Olszewski, J.L., Duda, D.M., Kurinov, I., Deng, A., Fenn, T.D., Klionsky, D...

OCA — Wed, 05 Sep 2012 04:57:54 GMT

New page: '''Unreleased structure''' The entry 4gsj is ON HOLD Authors: Kaiser, S.E., Mao, K., Taherbhoy, A.M., Yu, S., Olszewski, J.L., Duda, D.M., Kurinov, I., Deng, A., Fenn, T.D., Klionsky, D...

New page

'''Unreleased structure'''

The entry 4gsj is ON HOLD

Authors: Kaiser, S.E., Mao, K., Taherbhoy, A.M., Yu, S., Olszewski, J.L., Duda, D.M., Kurinov, I., Deng, A., Fenn, T.D., Klionsky, D.J., Schulman, B.A.

Description: E1