4gwg - Revision history

OCA at 15:58, 14 March 2024

OCA — Thu, 14 Mar 2024 15:58:20 GMT

←Older revision		Revision as of 15:58, 14 March 2024
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4gwg]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GWG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4GWG FirstGlance]. <br>		<table><tr><td colspan='2'>[[4gwg]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GWG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4GWG FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.3907Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4gwg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gwg OCA], [https://pdbe.org/4gwg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4gwg RCSB], [https://www.ebi.ac.uk/pdbsum/4gwg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4gwg ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4gwg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gwg OCA], [https://pdbe.org/4gwg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4gwg RCSB], [https://www.ebi.ac.uk/pdbsum/4gwg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4gwg ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[https://www.uniprot.org/uniprot/6PGD_HUMAN 6PGD_HUMAN] Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.		[https://www.uniprot.org/uniprot/6PGD_HUMAN 6PGD_HUMAN] Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
-	<div style="background-color:#fffaf0;">
-	== Publication Abstract from PubMed ==
-	It is unclear how cancer cells coordinate glycolysis and biosynthesis to support rapidly growing tumors. We found that the glycolytic enzyme phosphoglycerate mutase 1 (PGAM1), commonly upregulated in human cancers due to loss of TP53, contributes to biosynthesis regulation in part by controlling intracellular levels of its substrate, 3-phosphoglycerate (3-PG), and product, 2-phosphoglycerate (2-PG). 3-PG binds to and inhibits 6-phosphogluconate dehydrogenase in the oxidative pentose phosphate pathway (PPP), while 2-PG activates 3-phosphoglycerate dehydrogenase to provide feedback control of 3-PG levels. Inhibition of PGAM1 by shRNA or a small molecule inhibitor PGMI-004A results in increased 3-PG and decreased 2-PG levels in cancer cells, leading to significantly decreased glycolysis, PPP flux and biosynthesis, as well as attenuated cell proliferation and tumor growth.
-
-	Phosphoglycerate mutase 1 coordinates glycolysis and biosynthesis to promote tumor growth.,Hitosugi T, Zhou L, Elf S, Fan J, Kang HB, Seo JH, Shan C, Dai Q, Zhang L, Xie J, Gu TL, Jin P, Aleckovic M, Leroy G, Kang Y, Sudderth JA, Deberardinis RJ, Luan CH, Chen GZ, Muller S, Shin DM, Owonikoko TK, Lonial S, Arellano ML, Khoury HJ, Khuri FR, Lee BH, Ye K, Boggon TJ, Kang S, He C, Chen J Cancer Cell. 2012 Nov 13;22(5):585-600. doi: 10.1016/j.ccr.2012.09.020. PMID:23153533<ref>PMID:23153533</ref>
-
-	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	</div>
-	<div class="pdbe-citations 4gwg" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
	*[[6-phosphogluconate dehydrogenase 3D structures\|6-phosphogluconate dehydrogenase 3D structures]]		*[[6-phosphogluconate dehydrogenase 3D structures\|6-phosphogluconate dehydrogenase 3D structures]]
-	== References ==
-	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>

OCA at 07:23, 26 October 2022

OCA — Wed, 26 Oct 2022 07:23:01 GMT

←Older revision		Revision as of 07:23, 26 October 2022
Line 1:		Line 1:

	==Crystal Structure Analysis of 6-phosphogluconate dehydrogenase apo-form==		==Crystal Structure Analysis of 6-phosphogluconate dehydrogenase apo-form==
-	<StructureSection load='4gwg' size='340' side='right' caption='[[4gwg]], [[Resolution\|resolution]] 1.39Å' scene=''>	+	<StructureSection load='4gwg' size='340' side='right'caption='[[4gwg]], [[Resolution\|resolution]] 1.39Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4gwg]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Human Human~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GWG OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4GWG FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4gwg]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GWG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4GWG FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene~~></td></tr>~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene></td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2jkv\|2jkv]], [[4gwk\|4gwk]]</td></tr>~~	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4gwg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gwg OCA], [https://pdbe.org/4gwg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4gwg RCSB], [https://www.ebi.ac.uk/pdbsum/4gwg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4gwg ProSAT]</span></td></tr>
-	~~<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">PGD, PGDH ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>~~	+
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Phosphogluconate_dehydrogenase_(NADP(+)-dependent,_decarboxylating) Phosphogluconate dehydrogenase (NADP(+)-dependent, decarboxylating)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.44 1.1.1.44] </span></td></tr>	+
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4gwg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gwg OCA], [~~http~~://pdbe.org/4gwg PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4gwg RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4gwg PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4gwg ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/6PGD_HUMAN 6PGD_HUMAN]] Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.	+	[https://www.uniprot.org/uniprot/6PGD_HUMAN 6PGD_HUMAN] Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 21:		Line 18:
	</div>		</div>
	<div class="pdbe-citations 4gwg" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 4gwg" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[6-phosphogluconate dehydrogenase 3D structures\|6-phosphogluconate dehydrogenase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Human~~]]	+	[[Category: Homo sapiens]]
-	[[Category: ~~He, C~~]]	+	[[Category: Large Structures]]
-	[[Category: ~~Zhang, L~~]]	+	[[Category: He C]]
-	[[Category: ~~Zhou,~~ L]]	+	[[Category: Zhang L]]
-	[[Category: ~~6-phosphoglyconate dehydrogenase]]~~	+	[[Category: Zhou L]]
-	~~[[Category: Dehydrogenase]]~~	+
-	~~[[Category: Nadp]]~~	+
-	~~[[Category: Oxidoreductase~~]]	+

OCA at 19:58, 24 January 2018

OCA — Wed, 24 Jan 2018 19:58:33 GMT

←Older revision		Revision as of 19:58, 24 January 2018
Line 21:		Line 21:
	</div>		</div>
	<div class="pdbe-citations 4gwg" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 4gwg" style="background-color:#fffaf0;"></div>
-
-	==See Also==
-	*[[6-phosphogluconate dehydrogenase\|6-phosphogluconate dehydrogenase]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 10:22, 11 August 2016

OCA — Thu, 11 Aug 2016 10:22:57 GMT

←Older revision		Revision as of 10:22, 11 August 2016
Line 1:		Line 1:
		+
	==Crystal Structure Analysis of 6-phosphogluconate dehydrogenase apo-form==		==Crystal Structure Analysis of 6-phosphogluconate dehydrogenase apo-form==
	<StructureSection load='4gwg' size='340' side='right' caption='[[4gwg]], [[Resolution\|resolution]] 1.39Å' scene=''>		<StructureSection load='4gwg' size='340' side='right' caption='[[4gwg]], [[Resolution\|resolution]] 1.39Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4gwg]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Homo_sapiens Homo sapiens~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GWG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4GWG FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4gwg]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GWG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4GWG FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2jkv\|2jkv]], [[4gwk\|4gwk]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2jkv\|2jkv]], [[4gwk\|4gwk]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">PGD, PGDH ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 ~~Homo sapiens~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">PGD, PGDH ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Phosphogluconate_dehydrogenase_(~~decarboxylating~~) Phosphogluconate dehydrogenase (decarboxylating)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.44 1.1.1.44] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Phosphogluconate_dehydrogenase_(NADP(+)-dependent,_decarboxylating) Phosphogluconate dehydrogenase (NADP(+)-dependent, decarboxylating)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.44 1.1.1.44] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4gwg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gwg OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4gwg RCSB], [http://www.ebi.ac.uk/pdbsum/4gwg PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4gwg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gwg OCA], [http://pdbe.org/4gwg PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4gwg RCSB], [http://www.ebi.ac.uk/pdbsum/4gwg PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4gwg ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 19:		Line 20:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 4gwg" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 26:		Line 28:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Homo sapiens~~]]	+	[[Category: Human]]
	[[Category: He, C]]		[[Category: He, C]]
	[[Category: Zhang, L]]		[[Category: Zhang, L]]

OCA at 11:10, 25 January 2015

OCA — Sun, 25 Jan 2015 11:10:58 GMT

←Older revision		Revision as of 11:10, 25 January 2015
Line 1:		Line 1:
-	[[~~Image:~~4gwg.~~png~~\|~~left~~\|~~200px~~]]	+	==Crystal Structure Analysis of 6-phosphogluconate dehydrogenase apo-form==
		+	<StructureSection load='4gwg' size='340' side='right' caption='[[4gwg]], [[Resolution\|resolution]] 1.39Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[4gwg]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GWG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4GWG FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2jkv\|2jkv]], [[4gwk\|4gwk]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">PGD, PGDH ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
		+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Phosphogluconate_dehydrogenase_(decarboxylating) Phosphogluconate dehydrogenase (decarboxylating)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.44 1.1.1.44] </span></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4gwg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gwg OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4gwg RCSB], [http://www.ebi.ac.uk/pdbsum/4gwg PDBsum]</span></td></tr>
		+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/6PGD_HUMAN 6PGD_HUMAN]] Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	It is unclear how cancer cells coordinate glycolysis and biosynthesis to support rapidly growing tumors. We found that the glycolytic enzyme phosphoglycerate mutase 1 (PGAM1), commonly upregulated in human cancers due to loss of TP53, contributes to biosynthesis regulation in part by controlling intracellular levels of its substrate, 3-phosphoglycerate (3-PG), and product, 2-phosphoglycerate (2-PG). 3-PG binds to and inhibits 6-phosphogluconate dehydrogenase in the oxidative pentose phosphate pathway (PPP), while 2-PG activates 3-phosphoglycerate dehydrogenase to provide feedback control of 3-PG levels. Inhibition of PGAM1 by shRNA or a small molecule inhibitor PGMI-004A results in increased 3-PG and decreased 2-PG levels in cancer cells, leading to significantly decreased glycolysis, PPP flux and biosynthesis, as well as attenuated cell proliferation and tumor growth.

-	~~{{STRUCTURE_4gwg\| PDB=4gwg \| SCENE= }}~~	+	Phosphoglycerate mutase 1 coordinates glycolysis and biosynthesis to promote tumor growth.,Hitosugi T, Zhou L, Elf S, Fan J, Kang HB, Seo JH, Shan C, Dai Q, Zhang L, Xie J, Gu TL, Jin P, Aleckovic M, Leroy G, Kang Y, Sudderth JA, Deberardinis RJ, Luan CH, Chen GZ, Muller S, Shin DM, Owonikoko TK, Lonial S, Arellano ML, Khoury HJ, Khuri FR, Lee BH, Ye K, Boggon TJ, Kang S, He C, Chen J Cancer Cell. 2012 Nov 13;22(5):585-600. doi: 10.1016/j.ccr.2012.09.020. PMID:23153533<ref>PMID:23153533</ref>

-	~~===Crystal Structure Analysis~~ of ~~6-phosphogluconate dehydrogenase apo-form===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>

-	~~{{ABSTRACT_PUBMED_23153533}}~~	+	==See Also==
-		+	*[[6-phosphogluconate dehydrogenase\|6-phosphogluconate dehydrogenase]]
-	==~~About this Structure~~==	+	== References ==
-	[[~~4gwg~~]] ~~is a 1 chain structure with sequence from [http:~~//~~en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GWG OCA].~~	+	<references/>
		+	__TOC__
		+	</StructureSection>
	[[Category: Homo sapiens]]		[[Category: Homo sapiens]]
	[[Category: He, C]]		[[Category: He, C]]
-	[[Category: Zhang, L.]]	+	[[Category: Zhang, L]]
-	[[Category: Zhou, L.]]	+	[[Category: Zhou, L]]
	[[Category: 6-phosphoglyconate dehydrogenase]]		[[Category: 6-phosphoglyconate dehydrogenase]]
	[[Category: Dehydrogenase]]		[[Category: Dehydrogenase]]
	[[Category: Nadp]]		[[Category: Nadp]]
	[[Category: Oxidoreductase]]		[[Category: Oxidoreductase]]

OCA at 09:56, 5 December 2012

OCA — Wed, 05 Dec 2012 09:56:23 GMT

←Older revision		Revision as of 09:56, 5 December 2012
Line 1:		Line 1:
-	[[Image:4gwg.~~jpg~~\|left\|200px]]	+	[[Image:4gwg.png\|left\|200px]]

	{{STRUCTURE_4gwg\| PDB=4gwg \| SCENE= }}		{{STRUCTURE_4gwg\| PDB=4gwg \| SCENE= }}

OCA at 14:28, 28 November 2012

OCA — Wed, 28 Nov 2012 14:28:36 GMT

←Older revision		Revision as of 14:28, 28 November 2012
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	[[Image:4gwg.jpg\|left\|200px]]

-	~~The entry~~ 4gwg ~~is ON HOLD~~	+	{{STRUCTURE_4gwg\| PDB=4gwg \| SCENE= }}

-	~~Authors: He, C, Zhou, L., Zhang, L.~~	+	===Crystal Structure Analysis of 6-phosphogluconate dehydrogenase apo-form===

-	~~Description: Crystal~~ Structure ~~Analysis of~~ 6-~~phosphogluconate~~ dehydrogenase ~~apo-form~~	+	{{ABSTRACT_PUBMED_23153533}}
		+
		+	==About this Structure==
		+	[[4gwg]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GWG OCA].
		+	[[Category: Homo sapiens]]
		+	[[Category: He, C]]
		+	[[Category: Zhang, L.]]
		+	[[Category: Zhou, L.]]
		+	[[Category: 6-phosphoglyconate dehydrogenase]]
		+	[[Category: Dehydrogenase]]
		+	[[Category: Nadp]]
		+	[[Category: Oxidoreductase]]

OCA at 20:09, 26 September 2012

OCA — Wed, 26 Sep 2012 20:09:09 GMT

←Older revision		Revision as of 20:09, 26 September 2012
Line 3:		Line 3:
	The entry 4gwg is ON HOLD		The entry 4gwg is ON HOLD

-	Authors: He ~~Chuan~~, Zhou Lu, Zhang ~~Liang~~	+	Authors: He, C, Zhou, L., Zhang, L.

	Description: Crystal Structure Analysis of 6-phosphogluconate dehydrogenase apo-form		Description: Crystal Structure Analysis of 6-phosphogluconate dehydrogenase apo-form

OCA: Protected "4gwg" [edit=sysop:move=sysop]

OCA — Wed, 12 Sep 2012 04:54:36 GMT

Protected "4gwg" [edit=sysop:move=sysop]

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Revision as of 04:54, 12 September 2012

OCA: New page: '''Unreleased structure''' The entry 4gwg is ON HOLD Authors: He Chuan, Zhou Lu, Zhang Liang Description: Crystal Structure Analysis of 6-phosphogluconate dehydrogenase apo-form

OCA — Wed, 12 Sep 2012 04:54:35 GMT

New page: '''Unreleased structure''' The entry 4gwg is ON HOLD Authors: He Chuan, Zhou Lu, Zhang Liang Description: Crystal Structure Analysis of 6-phosphogluconate dehydrogenase apo-form

New page

'''Unreleased structure'''

The entry 4gwg is ON HOLD

Authors: He Chuan, Zhou Lu, Zhang Liang

Description: Crystal Structure Analysis of 6-phosphogluconate dehydrogenase apo-form