4h24 - Revision history

OCA at 14:58, 20 September 2023

OCA — Wed, 20 Sep 2023 14:58:47 GMT

←Older revision		Revision as of 14:58, 20 September 2023
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4h24]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Priestia_megaterium Priestia megaterium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4H24 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4H24 FirstGlance]. <br>		<table><tr><td colspan='2'>[[4h24]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Priestia_megaterium Priestia megaterium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4H24 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4H24 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.5Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4h24 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4h24 OCA], [https://pdbe.org/4h24 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4h24 RCSB], [https://www.ebi.ac.uk/pdbsum/4h24 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4h24 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4h24 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4h24 OCA], [https://pdbe.org/4h24 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4h24 RCSB], [https://www.ebi.ac.uk/pdbsum/4h24 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4h24 ProSAT]</span></td></tr>
	</table>		</table>

OCA at 07:54, 3 November 2022

OCA — Thu, 03 Nov 2022 07:54:45 GMT

←Older revision		Revision as of 07:54, 3 November 2022
Line 1:		Line 1:

	==Cytochrome P450BM3-CIS cyclopropanation catalyst==		==Cytochrome P450BM3-CIS cyclopropanation catalyst==
-	<StructureSection load='4h24' size='340' side='right' caption='[[4h24]], [[Resolution\|resolution]] 2.50Å' scene=''>	+	<StructureSection load='4h24' size='340' side='right'caption='[[4h24]], [[Resolution\|resolution]] 2.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4h24]] is a 4 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Atcc_14581 Atcc 14581~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4H24 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4H24 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4h24]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Priestia_megaterium Priestia megaterium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4H24 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4H24 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene~~></td></tr>~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4h23\|4h23]]</td></tr>~~	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4h24 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4h24 OCA], [https://pdbe.org/4h24 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4h24 RCSB], [https://www.ebi.ac.uk/pdbsum/4h24 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4h24 ProSAT]</span></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">CYP102A1, cyp102 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1404 ATCC 14581])</td></tr>	+
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Unspecific_monooxygenase Unspecific monooxygenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.14.1 1.14.14.1] </span></td></tr>	+
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4h24 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4h24 OCA], [~~http~~://pdbe.org/4h24 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4h24 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4h24 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4h24 ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/~~CPXB_BACME CPXB_BACME]~~] Functions as a fatty acid monooxygenase. Catalyzes hydroxylation of ~~medium and long-chain~~ fatty acids at omega-1, omega-2 and omega-3 positions, with optimum chain lengths of 12-16 carbons (lauric, myristic, and palmitic acids). ~~The~~ reductase domain ~~is required for~~ electron transfer from ~~NADP~~ to cytochrome P450.	+	[https://www.uniprot.org/uniprot/CPXB_PRIM2 CPXB_PRIM2] Functions as a fatty acid monooxygenase (PubMed:3106359, PubMed:1727637, PubMed:16566047, PubMed:7578081, PubMed:11695892, PubMed:14653735, PubMed:16403573, PubMed:18004886, PubMed:17077084, PubMed:17868686, PubMed:18298086, PubMed:18619466, PubMed:18721129, PubMed:19492389, PubMed:20180779, PubMed:21110374, PubMed:21875028). Catalyzes hydroxylation of fatty acids at omega-1, omega-2 and omega-3 positions (PubMed:1727637, PubMed:21875028). Shows activity toward medium and long-chain fatty acids, with optimum chain lengths of 12, 14 and 16 carbons (lauric, myristic, and palmitic acids). Able to metabolize some of these primary metabolites to secondary and tertiary products (PubMed:1727637). Marginal activity towards short chain lengths of 8-10 carbons (PubMed:1727637, PubMed:18619466). Hydroxylates highly branched fatty acids, which play an essential role in membrane fluidity regulation (PubMed:16566047). Also displays a NADPH-dependent reductase activity in the C-terminal domain, which allows electron transfer from NADPH to the heme iron of the cytochrome P450 N-terminal domain (PubMed:3106359, PubMed:1727637, PubMed:16566047, PubMed:7578081, PubMed:11695892, PubMed:14653735, PubMed:16403573, PubMed:18004886, PubMed:17077084, PubMed:17868686, PubMed:18298086, PubMed:18619466, PubMed:18721129, PubMed:19492389, PubMed:20180779, PubMed:21110374, PubMed:21875028). Involved in inactivation of quorum sensing signals of other competing bacteria by oxidazing efficiently acyl homoserine lactones (AHLs), molecules involved in quorum sensing signaling pathways, and their lactonolysis products acyl homoserines (AHs) (PubMed:18020460).<ref>PMID:11695892</ref> <ref>PMID:14653735</ref> <ref>PMID:16403573</ref> <ref>PMID:16566047</ref> <ref>PMID:17077084</ref> <ref>PMID:1727637</ref> <ref>PMID:17868686</ref> <ref>PMID:18004886</ref> <ref>PMID:18020460</ref> <ref>PMID:18298086</ref> <ref>PMID:18619466</ref> <ref>PMID:18721129</ref> <ref>PMID:19492389</ref> <ref>PMID:20180779</ref> <ref>PMID:21110374</ref> <ref>PMID:21875028</ref> <ref>PMID:3106359</ref> <ref>PMID:7578081</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 23:		Line 20:

	==See Also==		==See Also==
-	*[[Cytochrome P450\|Cytochrome P450]]	+	*[[Cytochrome P450 3D structures\|Cytochrome P450 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Atcc 14581~~]]	+	[[Category: Large Structures]]
-	[[Category: ~~Unspecific monooxygenase~~]]	+	[[Category: Priestia megaterium]]
-	[[Category: Arnold~~, F H~~]]	+	[[Category: Arnold FH]]
-	[[Category: Baril~~, S A~~]]	+	[[Category: Baril SA]]
-	[[Category: Brustad~~, E M~~]]	+	[[Category: Brustad EM]]
-	[[Category: Coelho~~, P S~~]]	+	[[Category: Coelho PS]]
-	[[Category: Ener~~, M E~~]]	+	[[Category: Ener ME]]
-	[[Category: Kannan, A]]	+	[[Category: Kannan A]]
-	[[Category: Wang~~, Z J]]~~	+	[[Category: Wang ZJ]]
-	~~[[Category: Cytochrome p450]]~~	+
-	~~[[Category: Directed evolution]]~~	+
-	~~[[Category: Enzymatic cyclopropanation]]~~	+
-	~~[[Category: Non-natural function]]~~	+
-	~~[[Category: Oxidoreductase~~]]	+

OCA at 19:57, 5 August 2016

OCA — Fri, 05 Aug 2016 19:57:00 GMT

←Older revision		Revision as of 19:57, 5 August 2016
Line 1:		Line 1:
		+
	==Cytochrome P450BM3-CIS cyclopropanation catalyst==		==Cytochrome P450BM3-CIS cyclopropanation catalyst==
	<StructureSection load='4h24' size='340' side='right' caption='[[4h24]], [[Resolution\|resolution]] 2.50Å' scene=''>		<StructureSection load='4h24' size='340' side='right' caption='[[4h24]], [[Resolution\|resolution]] 2.50Å' scene=''>
Line 7:		Line 8:
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">CYP102A1, cyp102 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1404 ATCC 14581])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">CYP102A1, cyp102 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1404 ATCC 14581])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Unspecific_monooxygenase Unspecific monooxygenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.14.1 1.14.14.1] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Unspecific_monooxygenase Unspecific monooxygenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.14.1 1.14.14.1] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4h24 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4h24 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4h24 RCSB], [http://www.ebi.ac.uk/pdbsum/4h24 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4h24 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4h24 OCA], [http://pdbe.org/4h24 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4h24 RCSB], [http://www.ebi.ac.uk/pdbsum/4h24 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4h24 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 19:		Line 20:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 4h24" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==

OCA at 21:29, 25 December 2014

OCA — Thu, 25 Dec 2014 21:29:00 GMT

←Older revision		Revision as of 21:29, 25 December 2014
Line 1:		Line 1:
-	~~{{STRUCTURE_4h24\| PDB~~=4h24 \| ~~SCENE~~= }}	+	==Cytochrome P450BM3-CIS cyclopropanation catalyst==
-	===~~Cytochrome P450BM3~~-~~CIS cyclopropanation catalyst~~===	+	<StructureSection load='4h24' size='340' side='right' caption='[[4h24]], [[Resolution\|resolution]] 2.50Å' scene=''>
-	~~{{ABSTRACT_PUBMED_23792734}}~~	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[4h24]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_14581 Atcc 14581]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4H24 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4H24 FirstGlance]. <br>
-	==Function==	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4h23\|4h23]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">CYP102A1, cyp102 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1404 ATCC 14581])</td></tr>
		+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Unspecific_monooxygenase Unspecific monooxygenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.14.1 1.14.14.1] </span></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4h24 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4h24 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4h24 RCSB], [http://www.ebi.ac.uk/pdbsum/4h24 PDBsum]</span></td></tr>
		+	</table>
		+	== Function ==
	[[http://www.uniprot.org/uniprot/CPXB_BACME CPXB_BACME]] Functions as a fatty acid monooxygenase. Catalyzes hydroxylation of medium and long-chain fatty acids at omega-1, omega-2 and omega-3 positions, with optimum chain lengths of 12-16 carbons (lauric, myristic, and palmitic acids). The reductase domain is required for electron transfer from NADP to cytochrome P450.		[[http://www.uniprot.org/uniprot/CPXB_BACME CPXB_BACME]] Functions as a fatty acid monooxygenase. Catalyzes hydroxylation of medium and long-chain fatty acids at omega-1, omega-2 and omega-3 positions, with optimum chain lengths of 12-16 carbons (lauric, myristic, and palmitic acids). The reductase domain is required for electron transfer from NADP to cytochrome P450.
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Whole-cell catalysts for non-natural chemical reactions will open new routes to sustainable production of chemicals. We designed a cytochrome 'P411' with unique serine-heme ligation that catalyzes efficient and selective olefin cyclopropanation in intact Escherichia coli cells. The mutation C400S in cytochrome P450BM3 gives a signature ferrous CO Soret peak at 411 nm, abolishes monooxygenation activity, raises the resting-state FeIII-to-FeII reduction potential and substantially improves NAD(P)H-driven activity.

-	~~==About this Structure==~~	+	A serine-substituted P450 catalyzes highly efficient carbene transfer to olefins in vivo.,Coelho PS, Wang ZJ, Ener ME, Baril SA, Kannan A, Arnold FH, Brustad EM Nat Chem Biol. 2013 Jun 23. doi: 10.1038/nchembio.1278. PMID:23792734<ref>PMID:23792734</ref>
-	~~[[4h24]] is a 4 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org~~/~~wiki/Atcc_14581 Atcc 14581]~~. ~~Full crystallographic information is available from [http~~://~~oca~~.~~weizmann~~.ac.il/~~oca-bin/ocashort?id=4H24 OCA].~~	+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>

	==See Also==		==See Also==
	*[[Cytochrome P450\|Cytochrome P450]]		*[[Cytochrome P450\|Cytochrome P450]]
-	*[[NADPH-Cytochrome P450 Reductase\|NADPH-Cytochrome P450 Reductase]]	+	== References ==
-		+	<references/>
-	==~~Reference~~==	+	__TOC__
-	~~<ref group="xtra">PMID:023792734</ref>~~<references ~~group="xtra"~~/><~~references~~/>	+	</StructureSection>
	[[Category: Atcc 14581]]		[[Category: Atcc 14581]]
	[[Category: Unspecific monooxygenase]]		[[Category: Unspecific monooxygenase]]
-	[[Category: Arnold, F H.]]	+	[[Category: Arnold, F H]]
-	[[Category: Baril, S A.]]	+	[[Category: Baril, S A]]
-	[[Category: Brustad, E M.]]	+	[[Category: Brustad, E M]]
-	[[Category: Coelho, P S.]]	+	[[Category: Coelho, P S]]
-	[[Category: Ener, M E.]]	+	[[Category: Ener, M E]]
-	[[Category: Kannan, A.]]	+	[[Category: Kannan, A]]
-	[[Category: Wang, Z J.]]	+	[[Category: Wang, Z J]]
	[[Category: Cytochrome p450]]		[[Category: Cytochrome p450]]
	[[Category: Directed evolution]]		[[Category: Directed evolution]]

OCA at 08:10, 18 December 2013

OCA — Wed, 18 Dec 2013 08:10:20 GMT

←Older revision		Revision as of 08:10, 18 December 2013
Line 1:		Line 1:
	{{STRUCTURE_4h24\| PDB=4h24 \| SCENE= }}		{{STRUCTURE_4h24\| PDB=4h24 \| SCENE= }}
-	===Cytochrome ~~P411BM3~~-CIS cyclopropanation catalyst===	+	===Cytochrome P450BM3-CIS cyclopropanation catalyst===
	{{ABSTRACT_PUBMED_23792734}}		{{ABSTRACT_PUBMED_23792734}}

Line 7:		Line 7:

	==About this Structure==		==About this Structure==
-	[[4h24]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Bacillus_megaterium Bacillus megaterium~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4H24 OCA].	+	[[4h24]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_14581 Atcc 14581]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4H24 OCA].
		+
		+	==See Also==
		+	*[[Cytochrome P450\|Cytochrome P450]]
		+	*[[NADPH-Cytochrome P450 Reductase\|NADPH-Cytochrome P450 Reductase]]

	==Reference==		==Reference==
	<ref group="xtra">PMID:023792734</ref><references group="xtra"/><references/>		<ref group="xtra">PMID:023792734</ref><references group="xtra"/><references/>
-	[[Category: ~~Bacillus megaterium~~]]	+	[[Category: Atcc 14581]]
	[[Category: Unspecific monooxygenase]]		[[Category: Unspecific monooxygenase]]
	[[Category: Arnold, F H.]]		[[Category: Arnold, F H.]]

OCA at 14:22, 10 July 2013

OCA — Wed, 10 Jul 2013 14:22:21 GMT

←Older revision		Revision as of 14:22, 10 July 2013
Line 1:		Line 1:
	{{STRUCTURE_4h24\| PDB=4h24 \| SCENE= }}		{{STRUCTURE_4h24\| PDB=4h24 \| SCENE= }}
	===Cytochrome P411BM3-CIS cyclopropanation catalyst===		===Cytochrome P411BM3-CIS cyclopropanation catalyst===
		+	{{ABSTRACT_PUBMED_23792734}}

	==Function==		==Function==
Line 7:		Line 8:
	==About this Structure==		==About this Structure==
	[[4h24]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_megaterium Bacillus megaterium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4H24 OCA].		[[4h24]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_megaterium Bacillus megaterium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4H24 OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:023792734</ref><references group="xtra"/><references/>
	[[Category: Bacillus megaterium]]		[[Category: Bacillus megaterium]]
	[[Category: Unspecific monooxygenase]]		[[Category: Unspecific monooxygenase]]

OCA at 10:26, 30 June 2013

OCA — Sun, 30 Jun 2013 10:26:22 GMT

←Older revision		Revision as of 10:26, 30 June 2013
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	{{STRUCTURE_4h24\| PDB=4h24 \| SCENE= }}
		+	===Cytochrome P411BM3-CIS cyclopropanation catalyst===

-	The ~~entry 4h24~~ is ~~ON HOLD until Paper Publication~~	+	==Function==
		+	[[http://www.uniprot.org/uniprot/CPXB_BACME CPXB_BACME]] Functions as a fatty acid monooxygenase. Catalyzes hydroxylation of medium and long-chain fatty acids at omega-1, omega-2 and omega-3 positions, with optimum chain lengths of 12-16 carbons (lauric, myristic, and palmitic acids). The reductase domain is required for electron transfer from NADP to cytochrome P450.

-	~~Authors~~: ~~Coelho, P~~.S.~~, Kannan, A~~.~~, Baril, S~~.A., Arnold, F.H., Brustad, E.M.	+	==About this Structure==
-		+	[[4h24]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_megaterium Bacillus megaterium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4H24 OCA].
-	~~Description~~: Cytochrome ~~P450~~-~~BM3 cyclopropanase C3C~~	+	[[Category: Bacillus megaterium]]
		+	[[Category: Unspecific monooxygenase]]
		+	[[Category: Arnold, F H.]]
		+	[[Category: Baril, S A.]]
		+	[[Category: Brustad, E M.]]
		+	[[Category: Coelho, P S.]]
		+	[[Category: Ener, M E.]]
		+	[[Category: Kannan, A.]]
		+	[[Category: Wang, Z J.]]
		+	[[Category: Cytochrome p450]]
		+	[[Category: Directed evolution]]
		+	[[Category: Enzymatic cyclopropanation]]
		+	[[Category: Non-natural function]]
		+	[[Category: Oxidoreductase]]

OCA at 20:10, 26 September 2012

OCA — Wed, 26 Sep 2012 20:10:57 GMT

←Older revision		Revision as of 20:10, 26 September 2012
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 4h24 is ON HOLD	+	The entry 4h24 is ON HOLD until Paper Publication

-	Authors: Coelho, P.S., Kannan, A., Baril, S.A., Arnold, F.H, Brustad, E.M.	+	Authors: Coelho, P.S., Kannan, A., Baril, S.A., Arnold, F.H., Brustad, E.M.

-	Description: Cytochrome P450-BM3 cyclopropanase C3C~~-C400S~~	+	Description: Cytochrome P450-BM3 cyclopropanase C3C

OCA: Protected "4h24" [edit=sysop:move=sysop]

OCA — Wed, 19 Sep 2012 06:58:09 GMT

Protected "4h24" [edit=sysop:move=sysop]

←Older revision

Revision as of 06:58, 19 September 2012

OCA: New page: '''Unreleased structure''' The entry 4h24 is ON HOLD Authors: Coelho, P.S., Kannan, A., Baril, S.A., Arnold, F.H, Brustad, E.M. Description: Cytochrome P450-BM3 cyclopropanase C3C-C400...

OCA — Wed, 19 Sep 2012 06:58:08 GMT

New page: '''Unreleased structure''' The entry 4h24 is ON HOLD Authors: Coelho, P.S., Kannan, A., Baril, S.A., Arnold, F.H, Brustad, E.M. Description: Cytochrome P450-BM3 cyclopropanase C3C-C400...

New page

'''Unreleased structure'''

The entry 4h24 is ON HOLD

Authors: Coelho, P.S., Kannan, A., Baril, S.A., Arnold, F.H, Brustad, E.M.

Description: Cytochrome P450-BM3 cyclopropanase C3C-C400S