4h3e - Revision history

OCA at 14:59, 20 September 2023

OCA — Wed, 20 Sep 2023 14:59:32 GMT

←Older revision		Revision as of 14:59, 20 September 2023
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4h3e]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Trypanosoma_cruzi_strain_CL_Brener Trypanosoma cruzi strain CL Brener]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4H3E OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4H3E FirstGlance]. <br>		<table><tr><td colspan='2'>[[4h3e]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Trypanosoma_cruzi_strain_CL_Brener Trypanosoma cruzi strain CL Brener]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4H3E OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4H3E FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FE2:FE+(II)+ION'>FE2</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.25Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FE2:FE+(II)+ION'>FE2</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4h3e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4h3e OCA], [https://pdbe.org/4h3e PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4h3e RCSB], [https://www.ebi.ac.uk/pdbsum/4h3e PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4h3e ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4h3e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4h3e OCA], [https://pdbe.org/4h3e PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4h3e RCSB], [https://www.ebi.ac.uk/pdbsum/4h3e PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4h3e ProSAT]</span></td></tr>
	</table>		</table>

OCA at 07:57, 3 November 2022

OCA — Thu, 03 Nov 2022 07:57:32 GMT

←Older revision		Revision as of 07:57, 3 November 2022
Line 1:		Line 1:

	==Crystal structure of a putative iron superoxide dismutase from Trypanosoma cruzi bound to iron==		==Crystal structure of a putative iron superoxide dismutase from Trypanosoma cruzi bound to iron==
-	<StructureSection load='4h3e' size='340' side='right' caption='[[4h3e]], [[Resolution\|resolution]] 2.25Å' scene=''>	+	<StructureSection load='4h3e' size='340' side='right'caption='[[4h3e]], [[Resolution\|resolution]] 2.25Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4h3e]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Trycc Trycc~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4H3E OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4H3E FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4h3e]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Trypanosoma_cruzi_strain_CL_Brener Trypanosoma cruzi strain CL Brener]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4H3E OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4H3E FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FE2:FE+(II)+ION'>FE2</scene~~></td></tr>~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FE2:FE+(II)+ION'>FE2</scene></td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4f2n\|4f2n]]</td></tr>~~	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4h3e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4h3e OCA], [https://pdbe.org/4h3e PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4h3e RCSB], [https://www.ebi.ac.uk/pdbsum/4h3e PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4h3e ProSAT]</span></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Tc00.1047053509775.40 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=353153 TRYCC])</td></tr>	+
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Superoxide_dismutase Superoxide dismutase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.15.1.1 1.15.1.1] </span></td></tr>	+
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4h3e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4h3e OCA], [~~http~~://pdbe.org/4h3e PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4h3e RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4h3e PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4h3e ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/Q4DCQ3_TRYCC Q4DCQ3_TRYCC]] Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity).[RuleBase:RU000414]	+	[https://www.uniprot.org/uniprot/Q4DCQ3_TRYCC Q4DCQ3_TRYCC] Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity).[RuleBase:RU000414]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 25:		Line 22:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Superoxide dismutase~~]]	+	[[Category: Large Structures]]
-	[[Category: ~~Trycc]]~~	+	[[Category: Trypanosoma cruzi strain CL Brener]]
-	~~[[Category: Structural genomic]]~~	+
-	~~[[Category: Antioxidant]]~~	+
-	~~[[Category: Chagas disease]]~~	+
-	~~[[Category: Hydrogen peroxide]]~~	+
-	~~[[Category: National institute of allergy and infectious disease]]~~	+
-	~~[[Category: Niaid]]~~	+
-	~~[[Category: Oxidoreductase]]~~	+
-	~~[[Category: Parasitic euglenoid trypanosome]]~~	+
-	~~[[Category: Radical oxygen species]]~~	+
-	~~[[Category: Radical scavenger]]~~	+
-	~~[[Category: Ssgcid]]~~	+
-	~~[[Category: Trypanosomiasis~~]]	+

OCA at 17:28, 9 March 2017

OCA — Thu, 09 Mar 2017 17:28:35 GMT

←Older revision		Revision as of 17:28, 9 March 2017
Line 1:		Line 1:
		+
	==Crystal structure of a putative iron superoxide dismutase from Trypanosoma cruzi bound to iron==		==Crystal structure of a putative iron superoxide dismutase from Trypanosoma cruzi bound to iron==
	<StructureSection load='4h3e' size='340' side='right' caption='[[4h3e]], [[Resolution\|resolution]] 2.25Å' scene=''>		<StructureSection load='4h3e' size='340' side='right' caption='[[4h3e]], [[Resolution\|resolution]] 2.25Å' scene=''>
Line 7:		Line 8:
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Tc00.1047053509775.40 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=353153 TRYCC])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Tc00.1047053509775.40 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=353153 TRYCC])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Superoxide_dismutase Superoxide dismutase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.15.1.1 1.15.1.1] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Superoxide_dismutase Superoxide dismutase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.15.1.1 1.15.1.1] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4h3e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4h3e OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4h3e RCSB], [http://www.ebi.ac.uk/pdbsum/4h3e PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4h3e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4h3e OCA], [http://pdbe.org/4h3e PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4h3e RCSB], [http://www.ebi.ac.uk/pdbsum/4h3e PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4h3e ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 19:		Line 20:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 4h3e" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 07:03, 3 June 2015

OCA — Wed, 03 Jun 2015 07:03:06 GMT

←Older revision		Revision as of 07:03, 3 June 2015
Line 2:		Line 2:
	<StructureSection load='4h3e' size='340' side='right' caption='[[4h3e]], [[Resolution\|resolution]] 2.25Å' scene=''>		<StructureSection load='4h3e' size='340' side='right' caption='[[4h3e]], [[Resolution\|resolution]] 2.25Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4h3e]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Trypanosoma_cruzi Trypanosoma cruzi~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4H3E OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4H3E FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4h3e]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Trycc Trycc]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4H3E OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4H3E FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FE2:FE+(II)+ION'>FE2</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FE2:FE+(II)+ION'>FE2</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4f2n\|4f2n]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4f2n\|4f2n]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Tc00.1047053509775.40 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=~~5693 Trypanosoma cruzi~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Tc00.1047053509775.40 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=353153 TRYCC])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Superoxide_dismutase Superoxide dismutase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.15.1.1 1.15.1.1] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Superoxide_dismutase Superoxide dismutase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.15.1.1 1.15.1.1] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4h3e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4h3e OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4h3e RCSB], [http://www.ebi.ac.uk/pdbsum/4h3e PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4h3e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4h3e OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4h3e RCSB], [http://www.ebi.ac.uk/pdbsum/4h3e PDBsum]</span></td></tr>
Line 11:		Line 11:
	== Function ==		== Function ==
	[[http://www.uniprot.org/uniprot/Q4DCQ3_TRYCC Q4DCQ3_TRYCC]] Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity).[RuleBase:RU000414]		[[http://www.uniprot.org/uniprot/Q4DCQ3_TRYCC Q4DCQ3_TRYCC]] Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity).[RuleBase:RU000414]
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Prior studies have highlighted the potential of superoxide dismutases as drug targets in eukaryotic pathogens. This report presents the structures of three iron-dependent superoxide dismutases (FeSODs) from Trypanosoma cruzi, Leishmania major and Babesia bovis. Comparison with existing structures from Plasmodium and other trypanosome isoforms shows a very conserved overall fold with subtle differences. In particular, structural data suggest that B. bovis FeSOD may display similar resistance to peroxynitrite-mediated inactivation via an intramolecular electron-transfer pathway as previously described in T. cruzi FeSOD isoform B, thus providing valuable information for structure-based drug design. Furthermore, lysine-acetylation results in T. cruzi indicate that acetylation occurs at a position close to that responsible for the regulation of acetylation-mediated activity in the human enzyme.
		+
		+	Iron superoxide dismutases in eukaryotic pathogens: new insights from Apicomplexa and Trypanosoma structures.,Phan IQ, Davies DR, Moretti NS, Shanmugam D, Cestari I, Anupama A, Fairman JW, Edwards TE, Stuart K, Schenkman S, Myler PJ Acta Crystallogr F Struct Biol Commun. 2015 May;71(Pt 5):615-21. doi:, 10.1107/S2053230X15004185. Epub 2015 May 7. PMID:25961325<ref>PMID:25961325</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: Superoxide dismutase]]		[[Category: Superoxide dismutase]]
-	[[Category: ~~Trypanosoma cruzi~~]]	+	[[Category: Trycc]]
	[[Category: Structural genomic]]		[[Category: Structural genomic]]
	[[Category: Antioxidant]]		[[Category: Antioxidant]]

OCA at 05:06, 25 December 2014

OCA — Thu, 25 Dec 2014 05:06:08 GMT

←Older revision		Revision as of 05:06, 25 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4h3e]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Trypanosoma_cruzi Trypanosoma cruzi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4H3E OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4H3E FirstGlance]. <br>		<table><tr><td colspan='2'>[[4h3e]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Trypanosoma_cruzi Trypanosoma cruzi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4H3E OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4H3E FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FE2:FE+(II)+ION'>FE2</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FE2:FE+(II)+ION'>FE2</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4f2n\|4f2n]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4f2n\|4f2n]]</td></tr>
-	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Tc00.1047053509775.40 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5693 Trypanosoma cruzi])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Tc00.1047053509775.40 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5693 Trypanosoma cruzi])</td></tr>
-	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Superoxide_dismutase Superoxide dismutase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.15.1.1 1.15.1.1] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Superoxide_dismutase Superoxide dismutase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.15.1.1 1.15.1.1] </span></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4h3e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4h3e OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4h3e RCSB], [http://www.ebi.ac.uk/pdbsum/4h3e PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4h3e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4h3e OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4h3e RCSB], [http://www.ebi.ac.uk/pdbsum/4h3e PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/Q4DCQ3_TRYCC Q4DCQ3_TRYCC]] Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity).[RuleBase:RU000414]
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: Superoxide dismutase]]		[[Category: Superoxide dismutase]]
	[[Category: Trypanosoma cruzi]]		[[Category: Trypanosoma cruzi]]
-	[[Category: ~~SSGCID, Seattle~~ Structural ~~Genomics Center for Infectious Disease.~~]]	+	[[Category: Structural genomic]]
	[[Category: Antioxidant]]		[[Category: Antioxidant]]
	[[Category: Chagas disease]]		[[Category: Chagas disease]]
Line 23:		Line 25:
	[[Category: Radical oxygen species]]		[[Category: Radical oxygen species]]
	[[Category: Radical scavenger]]		[[Category: Radical scavenger]]
-	[[Category: Seattle structural genomics center for infectious disease]]
	[[Category: Ssgcid]]		[[Category: Ssgcid]]
-	[[Category: Structural genomic]]
	[[Category: Trypanosomiasis]]		[[Category: Trypanosomiasis]]

OCA at 09:12, 2 July 2014

OCA — Wed, 02 Jul 2014 09:12:49 GMT

←Older revision		Revision as of 09:12, 2 July 2014
Line 1:		Line 1:
-	~~[[Image:4h3e.jpg\|left\|200px]]~~	+	==Crystal structure of a putative iron superoxide dismutase from Trypanosoma cruzi bound to iron==
-		+	<StructureSection load='4h3e' size='340' side='right' caption='[[4h3e]], [[Resolution\|resolution]] 2.25Å' scene=''>
-	~~{{STRUCTURE_4h3e\| PDB=4h3e \| SCENE= }}~~	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[4h3e]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Trypanosoma_cruzi Trypanosoma cruzi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4H3E OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4H3E FirstGlance]. <br>
-	===Crystal structure of a putative iron superoxide dismutase from Trypanosoma cruzi bound to iron===	+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FE2:FE+(II)+ION'>FE2</scene><br>
-		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4f2n\|4f2n]]</td></tr>
-		+	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Tc00.1047053509775.40 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5693 Trypanosoma cruzi])</td></tr>
-	==~~About this Structure~~==	+	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Superoxide_dismutase Superoxide dismutase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.15.1.1 1.15.1.1] </span></td></tr>
-	[[4h3e]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Trypanosoma_cruzi Trypanosoma cruzi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4H3E OCA].	+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4h3e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4h3e OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4h3e RCSB], [http://www.ebi.ac.uk/pdbsum/4h3e PDBsum]</span></td></tr>
		+	<table>
		+	__TOC__
		+	</StructureSection>
	[[Category: Superoxide dismutase]]		[[Category: Superoxide dismutase]]
	[[Category: Trypanosoma cruzi]]		[[Category: Trypanosoma cruzi]]

OCA at 20:53, 26 September 2012

OCA — Wed, 26 Sep 2012 20:53:13 GMT

←Older revision		Revision as of 20:53, 26 September 2012
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	[[Image:4h3e.jpg\|left\|200px]]

-	~~The entry~~ 4h3e ~~is ON HOLD~~	+	{{STRUCTURE_4h3e\| PDB=4h3e \| SCENE= }}

-	~~Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID)~~	+	===Crystal structure of a putative iron superoxide dismutase from Trypanosoma cruzi bound to iron===

-	~~Description: Crystal structure of~~ a ~~putative iron superoxide dismutase~~ from Trypanosoma cruzi ~~bound to iron~~	+
		+	==About this Structure==
		+	[[4h3e]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Trypanosoma_cruzi Trypanosoma cruzi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4H3E OCA].
		+	[[Category: Superoxide dismutase]]
		+	[[Category: Trypanosoma cruzi]]
		+	[[Category: SSGCID, Seattle Structural Genomics Center for Infectious Disease.]]
		+	[[Category: Antioxidant]]
		+	[[Category: Chagas disease]]
		+	[[Category: Hydrogen peroxide]]
		+	[[Category: National institute of allergy and infectious disease]]
		+	[[Category: Niaid]]
		+	[[Category: Oxidoreductase]]
		+	[[Category: Parasitic euglenoid trypanosome]]
		+	[[Category: Radical oxygen species]]
		+	[[Category: Radical scavenger]]
		+	[[Category: Seattle structural genomics center for infectious disease]]
		+	[[Category: Ssgcid]]
		+	[[Category: Structural genomic]]
		+	[[Category: Trypanosomiasis]]

OCA: Protected "4h3e" [edit=sysop:move=sysop]

OCA — Wed, 19 Sep 2012 06:59:28 GMT

Protected "4h3e" [edit=sysop:move=sysop]

←Older revision

Revision as of 06:59, 19 September 2012

OCA: New page: '''Unreleased structure''' The entry 4h3e is ON HOLD Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Description: Crystal structure of a putative iron super...

OCA — Wed, 19 Sep 2012 06:59:27 GMT

New page: '''Unreleased structure''' The entry 4h3e is ON HOLD Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Description: Crystal structure of a putative iron super...

New page

'''Unreleased structure'''

The entry 4h3e is ON HOLD

Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID)

Description: Crystal structure of a putative iron superoxide dismutase from Trypanosoma cruzi bound to iron