4hef - Revision history

OCA at 08:12, 3 November 2022

OCA — Thu, 03 Nov 2022 08:12:42 GMT

←Older revision		Revision as of 08:12, 3 November 2022
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	<StructureSection load='4hef' size='340' side='right'caption='[[4hef]], [[Resolution\|resolution]] 1.86Å' scene=''>		<StructureSection load='4hef' size='340' side='right'caption='[[4hef]], [[Resolution\|resolution]] 1.86Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4hef]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Pseae Pseae~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HEF OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=4HEF FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4hef]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa_PAO1 Pseudomonas aeruginosa PAO1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HEF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4HEF FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NXL:(2S,5R)-1-FORMYL-5-[(SULFOOXY)AMINO]PIPERIDINE-2-CARBOXAMIDE'>NXL</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NXL:(2S,5R)-1-FORMYL-5-[(SULFOOXY)AMINO]PIPERIDINE-2-CARBOXAMIDE'>NXL</scene></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">ampC, PA4110 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=208964 PSEAE])</td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4hef FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4hef OCA], [https://pdbe.org/4hef PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4hef RCSB], [https://www.ebi.ac.uk/pdbsum/4hef PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4hef ProSAT]</span></td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] </span></td></tr>	+
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=4hef FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4hef OCA], [~~http~~://pdbe.org/4hef PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4hef RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4hef PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4hef ProSAT]</span></td></tr>	+
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/AMPC_PSEAE AMPC_PSEAE]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 25:		Line 25:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Beta-lactamase]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Pseae~~]]	+	[[Category: Pseudomonas aeruginosa PAO1]]
-	[[Category: Lahiri~~, S D]]~~	+	[[Category: Lahiri SD]]
-	~~[[Category: B-lactamase]]~~	+
-	~~[[Category: Hydrolase]]~~	+
-	~~[[Category: Hydrolase-hydrolase inhibitor complex]]~~	+
-	~~[[Category: Periplasmic protein~~]]	+

OCA at 09:58, 16 September 2020

OCA — Wed, 16 Sep 2020 09:58:45 GMT

←Older revision		Revision as of 09:58, 16 September 2020
Line 1:		Line 1:

-	==~~Strcuture~~ of avibactam bound to Pseudomonas aeruginosa AmpC==	+	==Structure of avibactam bound to Pseudomonas aeruginosa AmpC==
-	<StructureSection load='4hef' size='340' side='right' caption='[[4hef]], [[Resolution\|resolution]] 1.86Å' scene=''>	+	<StructureSection load='4hef' size='340' side='right'caption='[[4hef]], [[Resolution\|resolution]] 1.86Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4hef]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseae Pseae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HEF OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4HEF FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4hef]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseae Pseae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HEF OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=4HEF FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NXL:(2S,5R)-1-FORMYL-5-[(SULFOOXY)AMINO]PIPERIDINE-2-CARBOXAMIDE'>NXL</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NXL:(2S,5R)-1-FORMYL-5-[(SULFOOXY)AMINO]PIPERIDINE-2-CARBOXAMIDE'>NXL</scene></td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">ampC, PA4110 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=208964 PSEAE])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">ampC, PA4110 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=208964 PSEAE])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4hef FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4hef OCA], [http://pdbe.org/4hef PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4hef RCSB], [http://www.ebi.ac.uk/pdbsum/4hef PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4hef ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=4hef FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4hef OCA], [http://pdbe.org/4hef PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4hef RCSB], [http://www.ebi.ac.uk/pdbsum/4hef PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4hef ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
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	</div>		</div>
	<div class="pdbe-citations 4hef" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 4hef" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Beta-lactamase 3D structures\|Beta-lactamase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 23:		Line 26:
	</StructureSection>		</StructureSection>
	[[Category: Beta-lactamase]]		[[Category: Beta-lactamase]]
		+	[[Category: Large Structures]]
	[[Category: Pseae]]		[[Category: Pseae]]
	[[Category: Lahiri, S D]]		[[Category: Lahiri, S D]]

OCA at 06:35, 7 February 2018

OCA — Wed, 07 Feb 2018 06:35:50 GMT

←Older revision		Revision as of 06:35, 7 February 2018
Line 18:		Line 18:
	</div>		</div>
	<div class="pdbe-citations 4hef" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 4hef" style="background-color:#fffaf0;"></div>
-
-	==See Also==
-	*[[Beta-lactamase\|Beta-lactamase]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 17:35, 9 March 2017

OCA — Thu, 09 Mar 2017 17:35:27 GMT

←Older revision		Revision as of 17:35, 9 March 2017
Line 1:		Line 1:
		+
	==Strcuture of avibactam bound to Pseudomonas aeruginosa AmpC==		==Strcuture of avibactam bound to Pseudomonas aeruginosa AmpC==
	<StructureSection load='4hef' size='340' side='right' caption='[[4hef]], [[Resolution\|resolution]] 1.86Å' scene=''>		<StructureSection load='4hef' size='340' side='right' caption='[[4hef]], [[Resolution\|resolution]] 1.86Å' scene=''>
Line 6:		Line 7:
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">ampC, PA4110 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=208964 PSEAE])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">ampC, PA4110 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=208964 PSEAE])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4hef FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4hef OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4hef RCSB], [http://www.ebi.ac.uk/pdbsum/4hef PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4hef FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4hef OCA], [http://pdbe.org/4hef PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4hef RCSB], [http://www.ebi.ac.uk/pdbsum/4hef PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4hef ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 16:		Line 17:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 4hef" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==

OCA at 06:55, 3 June 2015

OCA — Wed, 03 Jun 2015 06:55:20 GMT

←Older revision		Revision as of 06:55, 3 June 2015
Line 2:		Line 2:
	<StructureSection load='4hef' size='340' side='right' caption='[[4hef]], [[Resolution\|resolution]] 1.86Å' scene=''>		<StructureSection load='4hef' size='340' side='right' caption='[[4hef]], [[Resolution\|resolution]] 1.86Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4hef]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Pseudomonas_aeruginosa_pao1 Pseudomonas aeruginosa pao1~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HEF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4HEF FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4hef]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseae Pseae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HEF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4HEF FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NXL:(2S,5R)-1-FORMYL-5-[(SULFOOXY)AMINO]PIPERIDINE-2-CARBOXAMIDE'>NXL</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NXL:(2S,5R)-1-FORMYL-5-[(SULFOOXY)AMINO]PIPERIDINE-2-CARBOXAMIDE'>NXL</scene></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">ampC, PA4110 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=208964 ~~Pseudomonas aeruginosa PAO1~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">ampC, PA4110 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=208964 PSEAE])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4hef FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4hef OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4hef RCSB], [http://www.ebi.ac.uk/pdbsum/4hef PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4hef FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4hef OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4hef RCSB], [http://www.ebi.ac.uk/pdbsum/4hef PDBsum]</span></td></tr>
Line 24:		Line 24:
	</StructureSection>		</StructureSection>
	[[Category: Beta-lactamase]]		[[Category: Beta-lactamase]]
-	[[Category: ~~Pseudomonas aeruginosa pao1~~]]	+	[[Category: Pseae]]
	[[Category: Lahiri, S D]]		[[Category: Lahiri, S D]]
	[[Category: B-lactamase]]		[[Category: B-lactamase]]

OCA at 13:07, 21 December 2014

OCA — Sun, 21 Dec 2014 13:07:59 GMT

←Older revision		Revision as of 13:07, 21 December 2014
Line 1:		Line 1:
-	~~{{STRUCTURE_4hef~~\| ~~PDB~~=4hef \| ~~SCENE~~= }}	+	==Strcuture of avibactam bound to Pseudomonas aeruginosa AmpC==
-	===~~Strcuture~~ of avibactam bound to Pseudomonas aeruginosa AmpC~~===~~	+	<StructureSection load='4hef' size='340' side='right' caption='[[4hef]], [[Resolution\|resolution]] 1.86Å' scene=''>
-	~~{{ABSTRACT_PUBMED_23439634}}~~	+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[4hef]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa_pao1 Pseudomonas aeruginosa pao1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HEF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4HEF FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NXL:(2S,5R)-1-FORMYL-5-[(SULFOOXY)AMINO]PIPERIDINE-2-CARBOXAMIDE'>NXL</scene></td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">ampC, PA4110 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=208964 Pseudomonas aeruginosa PAO1])</td></tr>
		+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] </span></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4hef FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4hef OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4hef RCSB], [http://www.ebi.ac.uk/pdbsum/4hef PDBsum]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Although beta-lactams have been the most effective class of antibacterial agents used in clinical practice for the past half century, their effectiveness on Gram-negative bacteria has been eroded due to the emergence and spread of beta-lactamase enzymes that are not affected by currently marketed beta-lactam/beta-lactamase inhibitor combinations. Avibactam is a novel, covalent, non-beta-lactam beta-lactamase inhibitor presently in clinical development in combination with either ceftaroline or ceftazidime. In vitro studies show that avibactam may restore the broad-spectrum activity of cephalosporins against class A, class C and some class D beta-lactamases. Here we describe the structure of two clinically important beta-lactamase enzymes bound to avibactam, the class A CTX-M-15 extended-spectrum beta-lactamase and class C Pseudomonas aeruginosa AmpC beta-lactamase, which together provide insight into the binding modes for the respective enzyme classes. The structure reveals a similar binding mode in both enzymes and thus provides a rationale for the broad-spectrum inhibitory activity of avibactam. Identification of the key residues surrounding the binding pocket allows for a better understanding of the potency of this scaffold. Finally, avibactam has recently been shown to be a reversible inhibitor and the structure provides insights into the mechanism of avibactam recyclization. Analysis of the ultra-high resolution CTX-M-15 structure suggests how the deacylation mechanism favors recyclization over hydrolysis.

-	~~==About this Structure==~~	+	Structural Insight into Potent Broad-spectrum Inhibition with Reversible Recyclization Mechanism: Avibactam in Complex with CTX-M-15 and Pseudomonas aeruginosa AmpC beta-lactamases.,Lahiri SD, Mangani S, Durand-Reville T, Benvenuti M, De Luca F, Sanyal G, Docquier JD Antimicrob Agents Chemother. 2013 Feb 25. PMID:23439634<ref>PMID:23439634</ref>
-	~~[[4hef]] is a 1 chain structure~~ with ~~sequence from [http~~:~~//en.wikipedia.org/wiki/Pseudomonas_aeruginosa_pao1~~ Pseudomonas aeruginosa ~~pao1]~~. ~~Full crystallographic information is available from [http://oca~~.~~weizmann~~.~~ac.il~~/~~oca-bin/ocashort?id=4HEF OCA].~~	+

-	==~~Reference~~==	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	~~<ref group~~=~~"xtra">PMID:023439634</ref>~~<references ~~group="xtra"~~/><~~references~~/>	+	</div>
		+
		+	==See Also==
		+	*[[Beta-lactamase\|Beta-lactamase]]
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
	[[Category: Beta-lactamase]]		[[Category: Beta-lactamase]]
	[[Category: Pseudomonas aeruginosa pao1]]		[[Category: Pseudomonas aeruginosa pao1]]
-	[[Category: Lahiri, S D.]]	+	[[Category: Lahiri, S D]]
	[[Category: B-lactamase]]		[[Category: B-lactamase]]
	[[Category: Hydrolase]]		[[Category: Hydrolase]]
	[[Category: Hydrolase-hydrolase inhibitor complex]]		[[Category: Hydrolase-hydrolase inhibitor complex]]
	[[Category: Periplasmic protein]]		[[Category: Periplasmic protein]]

OCA at 16:08, 19 June 2013

OCA — Wed, 19 Jun 2013 16:08:50 GMT

←Older revision		Revision as of 16:08, 19 June 2013
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	{{STRUCTURE_4hef\| PDB=4hef \| SCENE= }}
		+	===Strcuture of avibactam bound to Pseudomonas aeruginosa AmpC===
		+	{{ABSTRACT_PUBMED_23439634}}

-	~~The entry~~ 4hef is ~~ON HOLD until Paper Publication~~	+	==About this Structure==
		+	[[4hef]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa_pao1 Pseudomonas aeruginosa pao1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HEF OCA].

-	~~Authors~~: Lahiri, S.D.	+	==Reference==
-		+	<ref group="xtra">PMID:023439634</ref><references group="xtra"/><references/>
-	~~Description~~: ~~Strcuture of avibactam bound to Pseudomonas aeruginosa AmpC~~	+	[[Category: Beta-lactamase]]
		+	[[Category: Pseudomonas aeruginosa pao1]]
		+	[[Category: Lahiri, S D.]]
		+	[[Category: B-lactamase]]
		+	[[Category: Hydrolase]]
		+	[[Category: Hydrolase-hydrolase inhibitor complex]]
		+	[[Category: Periplasmic protein]]

OCA at 13:19, 20 February 2013

OCA — Wed, 20 Feb 2013 13:19:57 GMT

←Older revision		Revision as of 13:19, 20 February 2013
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 4hef is ON HOLD	+	The entry 4hef is ON HOLD until Paper Publication

	Authors: Lahiri, S.D.		Authors: Lahiri, S.D.

	Description: Strcuture of avibactam bound to Pseudomonas aeruginosa AmpC		Description: Strcuture of avibactam bound to Pseudomonas aeruginosa AmpC

OCA: Protected "4hef" [edit=sysop:move=sysop]

OCA — Wed, 10 Oct 2012 07:01:32 GMT

Protected "4hef" [edit=sysop:move=sysop]

←Older revision

Revision as of 07:01, 10 October 2012

OCA: New page: '''Unreleased structure''' The entry 4hef is ON HOLD Authors: Lahiri, S.D. Description: Strcuture of avibactam bound to Pseudomonas aeruginosa AmpC

OCA — Wed, 10 Oct 2012 07:01:31 GMT

New page: '''Unreleased structure''' The entry 4hef is ON HOLD Authors: Lahiri, S.D. Description: Strcuture of avibactam bound to Pseudomonas aeruginosa AmpC

New page

'''Unreleased structure'''

The entry 4hef is ON HOLD

Authors: Lahiri, S.D.

Description: Strcuture of avibactam bound to Pseudomonas aeruginosa AmpC