4hfi - Revision history

OCA at 11:40, 1 March 2024

OCA — Fri, 01 Mar 2024 11:40:35 GMT

←Older revision		Revision as of 11:40, 1 March 2024
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4hfi]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Gloeobacter_violaceus_PCC_7421 Gloeobacter violaceus PCC 7421]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HFI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4HFI FirstGlance]. <br>		<table><tr><td colspan='2'>[[4hfi]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Gloeobacter_violaceus_PCC_7421 Gloeobacter violaceus PCC 7421]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HFI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4HFI FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=LMT:DODECYL-BETA-D-MALTOSIDE'>LMT</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PLC:DIUNDECYL+PHOSPHATIDYL+CHOLINE'>PLC</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.4Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=LMT:DODECYL-BETA-D-MALTOSIDE'>LMT</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PLC:DIUNDECYL+PHOSPHATIDYL+CHOLINE'>PLC</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4hfi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4hfi OCA], [https://pdbe.org/4hfi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4hfi RCSB], [https://www.ebi.ac.uk/pdbsum/4hfi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4hfi ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4hfi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4hfi OCA], [https://pdbe.org/4hfi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4hfi RCSB], [https://www.ebi.ac.uk/pdbsum/4hfi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4hfi ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[https://www.uniprot.org/uniprot/GLIC_GLOVI GLIC_GLOVI] Cationic channel with similar permeabilities for Na(+) and K(+), that is activated by an increase of the proton concentration on the extracellular side. Displays no permeability for chloride ions. Shows slow kinetics of activation, no desensitization and a single channel conductance of 8 pS. Might contribute to adaptation to external pH change.<ref>PMID:17167423</ref>		[https://www.uniprot.org/uniprot/GLIC_GLOVI GLIC_GLOVI] Cationic channel with similar permeabilities for Na(+) and K(+), that is activated by an increase of the proton concentration on the extracellular side. Displays no permeability for chloride ions. Shows slow kinetics of activation, no desensitization and a single channel conductance of 8 pS. Might contribute to adaptation to external pH change.<ref>PMID:17167423</ref>
-	<div style="background-color:#fffaf0;">
-	== Publication Abstract from PubMed ==
-	To understand the molecular mechanism of ion permeation in pentameric ligand-gated ion channels (pLGIC), we solved the structure of an open form of GLIC, a prokaryotic pLGIC, at 2.4 A. Anomalous diffraction data were used to place bound anions and cations. This reveals ordered water molecules at the level of two rings of hydroxylated residues (named Ser6' and Thr2') that contribute to the ion selectivity filter. Two water pentagons are observed, a self-stabilized ice-like water pentagon and a second wider water pentagon, with one sodium ion between them. Single-channel electrophysiology shows that the side-chain hydroxyl of Ser6' is crucial for ion translocation. Simulations and electrostatics calculations complemented the description of hydration in the pore and suggest that the water pentagons observed in the crystal are important for the ion to cross hydrophobic constriction barriers. Simulations that pull a cation through the pore reveal that residue Ser6' actively contributes to ion translocation by reorienting its side chain when the ion is going through the pore. Generalization of these findings to the pLGIC family is proposed.
-
-	Structural basis for ion permeation mechanism in pentameric ligand-gated ion channels.,Sauguet L, Poitevin F, Murail S, Van Renterghem C, Moraga-Cid G, Malherbe L, Thompson AW, Koehl P, Corringer PJ, Baaden M, Delarue M EMBO J. 2013 Feb 12;32(5):728-41. doi: 10.1038/emboj.2013.17. Epub 2013 Feb 12. PMID:23403925<ref>PMID:23403925</ref>
-
-	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	</div>
-	<div class="pdbe-citations 4hfi" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==

OCA at 08:13, 3 November 2022

OCA — Thu, 03 Nov 2022 08:13:54 GMT

←Older revision		Revision as of 08:13, 3 November 2022
Line 1:		Line 1:

	==The GLIC pentameric Ligand-Gated Ion Channel at 2.4 A resolution==		==The GLIC pentameric Ligand-Gated Ion Channel at 2.4 A resolution==
-	<StructureSection load='4hfi' size='340' side='right' caption='[[4hfi]], [[Resolution\|resolution]] 2.40Å' scene=''>	+	<StructureSection load='4hfi' size='340' side='right'caption='[[4hfi]], [[Resolution\|resolution]] 2.40Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4hfi]] is a 5 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Glovi Glovi~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HFI OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4HFI FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4hfi]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Gloeobacter_violaceus_PCC_7421 Gloeobacter violaceus PCC 7421]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HFI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4HFI FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=LMT:DODECYL-BETA-D-MALTOSIDE'>LMT</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PLC:DIUNDECYL+PHOSPHATIDYL+CHOLINE'>PLC</scene>~~</td></tr>~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=LMT:DODECYL-BETA-D-MALTOSIDE'>LMT</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PLC:DIUNDECYL+PHOSPHATIDYL+CHOLINE'>PLC</scene></td></tr>
-	~~<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">glvI, glr4197 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=251221 GLOVI])~~</td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4hfi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4hfi OCA], [https://pdbe.org/4hfi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4hfi RCSB], [https://www.ebi.ac.uk/pdbsum/4hfi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4hfi ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4hfi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4hfi OCA], [~~http~~://pdbe.org/4hfi PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4hfi RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4hfi PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4hfi ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/GLIC_GLOVI GLIC_GLOVI]] Cationic channel with similar permeabilities for Na(+) and K(+), that is activated by an increase of the proton concentration on the extracellular side. Displays no permeability for chloride ions. Shows slow kinetics of activation, no desensitization and a single channel conductance of 8 pS. Might contribute to adaptation to external pH change.<ref>PMID:17167423</ref>	+	[https://www.uniprot.org/uniprot/GLIC_GLOVI GLIC_GLOVI] Cationic channel with similar permeabilities for Na(+) and K(+), that is activated by an increase of the proton concentration on the extracellular side. Displays no permeability for chloride ions. Shows slow kinetics of activation, no desensitization and a single channel conductance of 8 pS. Might contribute to adaptation to external pH change.<ref>PMID:17167423</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 21:		Line 20:

	==See Also==		==See Also==
-	*[[Ion channels\|Ion channels]]	+	*[[Ion channels 3D structures\|Ion channels 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Glovi~~]]	+	[[Category: Gloeobacter violaceus PCC 7421]]
-	[[Category: ~~Corringer, P J~~]]	+	[[Category: Large Structures]]
-	[[Category: ~~Delarue, M~~]]	+	[[Category: Corringer PJ]]
-	[[Category: ~~Sauguet, L~~]]	+	[[Category: Delarue M]]
-	[[Category: ~~Ion channel]]~~	+	[[Category: Sauguet L]]
-	~~[[Category: Membrane protein]]~~	+
-	~~[[Category: Pentameric transmembrane channel]]~~	+
-	~~[[Category: Transport protein~~]]	+

OCA at 15:25, 4 August 2016

OCA — Thu, 04 Aug 2016 15:25:00 GMT

←Older revision		Revision as of 15:25, 4 August 2016
Line 1:		Line 1:
		+
	==The GLIC pentameric Ligand-Gated Ion Channel at 2.4 A resolution==		==The GLIC pentameric Ligand-Gated Ion Channel at 2.4 A resolution==
	<StructureSection load='4hfi' size='340' side='right' caption='[[4hfi]], [[Resolution\|resolution]] 2.40Å' scene=''>		<StructureSection load='4hfi' size='340' side='right' caption='[[4hfi]], [[Resolution\|resolution]] 2.40Å' scene=''>
Line 5:		Line 6:
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=LMT:DODECYL-BETA-D-MALTOSIDE'>LMT</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PLC:DIUNDECYL+PHOSPHATIDYL+CHOLINE'>PLC</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=LMT:DODECYL-BETA-D-MALTOSIDE'>LMT</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PLC:DIUNDECYL+PHOSPHATIDYL+CHOLINE'>PLC</scene></td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">glvI, glr4197 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=251221 GLOVI])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">glvI, glr4197 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=251221 GLOVI])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4hfi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4hfi OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4hfi RCSB], [http://www.ebi.ac.uk/pdbsum/4hfi PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4hfi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4hfi OCA], [http://pdbe.org/4hfi PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4hfi RCSB], [http://www.ebi.ac.uk/pdbsum/4hfi PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4hfi ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 17:		Line 18:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 4hfi" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Ion channels\|Ion channels]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 16:23, 24 December 2014

OCA — Wed, 24 Dec 2014 16:23:18 GMT

←Older revision		Revision as of 16:23, 24 December 2014
Line 7:		Line 7:
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4hfi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4hfi OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4hfi RCSB], [http://www.ebi.ac.uk/pdbsum/4hfi PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4hfi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4hfi OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4hfi RCSB], [http://www.ebi.ac.uk/pdbsum/4hfi PDBsum]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/GLIC_GLOVI GLIC_GLOVI]] Cationic channel with similar permeabilities for Na(+) and K(+), that is activated by an increase of the proton concentration on the extracellular side. Displays no permeability for chloride ions. Shows slow kinetics of activation, no desensitization and a single channel conductance of 8 pS. Might contribute to adaptation to external pH change.<ref>PMID:17167423</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==

OCA at 09:40, 10 December 2014

OCA — Wed, 10 Dec 2014 09:40:38 GMT

←Older revision		Revision as of 09:40, 10 December 2014
Line 1:		Line 1:
-	[[~~Image:~~4hfi.~~jpg~~\|~~left~~\|~~200px~~]]	+	==The GLIC pentameric Ligand-Gated Ion Channel at 2.4 A resolution==
		+	<StructureSection load='4hfi' size='340' side='right' caption='[[4hfi]], [[Resolution\|resolution]] 2.40Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[4hfi]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Glovi Glovi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HFI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4HFI FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=LMT:DODECYL-BETA-D-MALTOSIDE'>LMT</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PLC:DIUNDECYL+PHOSPHATIDYL+CHOLINE'>PLC</scene></td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">glvI, glr4197 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=251221 GLOVI])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4hfi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4hfi OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4hfi RCSB], [http://www.ebi.ac.uk/pdbsum/4hfi PDBsum]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	To understand the molecular mechanism of ion permeation in pentameric ligand-gated ion channels (pLGIC), we solved the structure of an open form of GLIC, a prokaryotic pLGIC, at 2.4 A. Anomalous diffraction data were used to place bound anions and cations. This reveals ordered water molecules at the level of two rings of hydroxylated residues (named Ser6' and Thr2') that contribute to the ion selectivity filter. Two water pentagons are observed, a self-stabilized ice-like water pentagon and a second wider water pentagon, with one sodium ion between them. Single-channel electrophysiology shows that the side-chain hydroxyl of Ser6' is crucial for ion translocation. Simulations and electrostatics calculations complemented the description of hydration in the pore and suggest that the water pentagons observed in the crystal are important for the ion to cross hydrophobic constriction barriers. Simulations that pull a cation through the pore reveal that residue Ser6' actively contributes to ion translocation by reorienting its side chain when the ion is going through the pore. Generalization of these findings to the pLGIC family is proposed.

-	~~{{STRUCTURE_4hfi\| PDB=4hfi \| SCENE= }}~~	+	Structural basis for ion permeation mechanism in pentameric ligand-gated ion channels.,Sauguet L, Poitevin F, Murail S, Van Renterghem C, Moraga-Cid G, Malherbe L, Thompson AW, Koehl P, Corringer PJ, Baaden M, Delarue M EMBO J. 2013 Feb 12;32(5):728-41. doi: 10.1038/emboj.2013.17. Epub 2013 Feb 12. PMID:23403925<ref>PMID:23403925</ref>

-	~~===The GLIC pentameric Ligand-Gated Ion Channel at 2~~.~~4 A resolution===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-		+	== References ==
-	==~~About this Structure~~==	+	<references/>
-	~~[[4hfi]] is a 5 chain structure with sequence from [http:~~//~~en.wikipedia.org/wiki/Gloeobacter_violaceus_pcc_7421 Gloeobacter violaceus pcc 7421]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HFI OCA].~~	+	__TOC__
-	[[Category: ~~Gloeobacter violaceus pcc 7421~~]]	+	</StructureSection>
-	[[Category: Corringer, P J.]]	+	[[Category: Glovi]]
-	[[Category: Delarue, M.]]	+	[[Category: Corringer, P J]]
-	[[Category: Sauguet, L.]]	+	[[Category: Delarue, M]]
		+	[[Category: Sauguet, L]]
	[[Category: Ion channel]]		[[Category: Ion channel]]
	[[Category: Membrane protein]]		[[Category: Membrane protein]]
	[[Category: Pentameric transmembrane channel]]		[[Category: Pentameric transmembrane channel]]
	[[Category: Transport protein]]		[[Category: Transport protein]]

OCA at 13:59, 20 February 2013

OCA — Wed, 20 Feb 2013 13:59:12 GMT

←Older revision		Revision as of 13:59, 20 February 2013
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	[[Image:4hfi.jpg\|left\|200px]]

-	~~The entry~~ 4hfi ~~is ON HOLD~~ ~~until Paper Publication~~	+	{{STRUCTURE_4hfi\| PDB=4hfi \| SCENE= }}

-	~~Authors: Sauguet, L., Corringer, P.J., Delarue, M~~.	+	===The GLIC pentameric Ligand-Gated Ion Channel at 2.4 A resolution===

-	~~Description~~: ~~The GLIC pentameric Ligand~~-~~Gated Ion Channel at 2~~.~~4 A resolution~~	+
		+	==About this Structure==
		+	[[4hfi]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Gloeobacter_violaceus_pcc_7421 Gloeobacter violaceus pcc 7421]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HFI OCA].
		+	[[Category: Gloeobacter violaceus pcc 7421]]
		+	[[Category: Corringer, P J.]]
		+	[[Category: Delarue, M.]]
		+	[[Category: Sauguet, L.]]
		+	[[Category: Ion channel]]
		+	[[Category: Membrane protein]]
		+	[[Category: Pentameric transmembrane channel]]
		+	[[Category: Transport protein]]

OCA at 10:00, 13 February 2013

OCA — Wed, 13 Feb 2013 10:00:18 GMT

←Older revision		Revision as of 10:00, 13 February 2013
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 4hfi is ON HOLD	+	The entry 4hfi is ON HOLD until Paper Publication

	Authors: Sauguet, L., Corringer, P.J., Delarue, M.		Authors: Sauguet, L., Corringer, P.J., Delarue, M.

	Description: The GLIC pentameric Ligand-Gated Ion Channel at 2.4 A resolution		Description: The GLIC pentameric Ligand-Gated Ion Channel at 2.4 A resolution

OCA: Protected "4hfi" [edit=sysop:move=sysop]

OCA — Wed, 17 Oct 2012 06:35:59 GMT

Protected "4hfi" [edit=sysop:move=sysop]

←Older revision

Revision as of 06:35, 17 October 2012

OCA: New page: '''Unreleased structure''' The entry 4hfi is ON HOLD Authors: Sauguet, L., Corringer, P.J., Delarue, M. Description: The GLIC pentameric Ligand-Gated Ion Channel at 2.4 A resolution

OCA — Wed, 17 Oct 2012 06:35:58 GMT

New page: '''Unreleased structure''' The entry 4hfi is ON HOLD Authors: Sauguet, L., Corringer, P.J., Delarue, M. Description: The GLIC pentameric Ligand-Gated Ion Channel at 2.4 A resolution

New page

'''Unreleased structure'''

The entry 4hfi is ON HOLD

Authors: Sauguet, L., Corringer, P.J., Delarue, M.

Description: The GLIC pentameric Ligand-Gated Ion Channel at 2.4 A resolution