4hke - Revision history

OCA at 14:08, 8 November 2023

OCA — Wed, 08 Nov 2023 14:08:04 GMT

←Older revision		Revision as of 14:08, 8 November 2023
Line 1:		Line 1:

	==Crystal Structure of MoxT of Bacillus anthracis==		==Crystal Structure of MoxT of Bacillus anthracis==
-	<StructureSection load='4hke' size='340' side='right'caption='[[4hke]]' scene=''>	+	<StructureSection load='4hke' size='340' side='right'caption='[[4hke]], [[Resolution\|resolution]] 1.87Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HKE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4HKE FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4hke]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_anthracis Bacillus anthracis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HKE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4HKE FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4hke FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4hke OCA], [https://pdbe.org/4hke PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4hke RCSB], [https://www.ebi.ac.uk/pdbsum/4hke PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4hke ProSAT]</span></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.87Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4hke FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4hke OCA], [https://pdbe.org/4hke PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4hke RCSB], [https://www.ebi.ac.uk/pdbsum/4hke PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4hke ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/A0A6H3ADX7_BACAN A0A6H3ADX7_BACAN] Toxic component of a type II toxin-antitoxin (TA) system.[PIRNR:PIRNR033490]
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Bacillus anthracis MoxXT is a Type II proteic Toxin-Antitoxin (TA) module wherein MoxT is a ribonuclease that cleaves RNA specifically while MoxX interacts with MoxT and inhibits its activity. Disruption of the TA interaction has been proposed as a novel antibacterial strategy. Peptides, either based on antitoxin sequence or rationally designed, have previously been reported to disrupt the MoxXT interaction but cause a decrease in MoxT ribonuclease activity. In the present study, we report the crystal structure of MoxT, and the effect of several peptides in disrupting the MoxXT interaction as well as augmentation of MoxT ribonuclease activity by binding to MoxT in vitro. Docking studies on the peptides were carried out in order to explain the observed structure activity relationships. The peptides with ribonuclease augmentation activity possess a distinct structure and are proposed to bind to a distinct site on MoxT. The docking of the active peptides with MoxT showed that they possess an aromatic group that occupies a conserved hydrophobic pocket. Additionally, the peptides inducing high ribonuclease activity were anchored by a negatively charged group near a cluster of positively charged residues present near the pocket. Our study provides a structural basis and rationale for the observed properties of the peptides and may aid the development of small molecules to disrupt the TA interaction.
		+
		+	Structural basis of Bacillus anthracis MoxXT disruption and the modulation of MoxT ribonuclease activity by rationally designed peptides.,Verma S, Kumar S, Gupta VP, Gourinath S, Bhatnagar S, Bhatnagar R J Biomol Struct Dyn. 2014 Mar 21. PMID:24650157<ref>PMID:24650157</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	<div class="pdbe-citations 4hke" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Bacillus anthracis]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Bhatnagar R]]		[[Category: Bhatnagar R]]

OCA at 10:43, 31 August 2022

OCA — Wed, 31 Aug 2022 10:43:30 GMT

←Older revision		Revision as of 10:43, 31 August 2022
Line 1:		Line 1:

	==Crystal Structure of MoxT of Bacillus anthracis==		==Crystal Structure of MoxT of Bacillus anthracis==
-	<StructureSection load='4hke' size='340' side='right'caption='[[4hke]]~~, [[Resolution\|resolution]] 1.87Å~~' scene=''>	+	<StructureSection load='4hke' size='340' side='right'caption='[[4hke]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>~~[[4hke]] is a 2 chain structure.~~ Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HKE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4HKE FirstGlance]. <br>	+	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HKE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4HKE FirstGlance]. <br>
-	</td></tr>~~<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>~~	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4hke FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4hke OCA], [https://pdbe.org/4hke PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4hke RCSB], [https://www.ebi.ac.uk/pdbsum/4hke PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4hke ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4hke FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4hke OCA], [https://pdbe.org/4hke PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4hke RCSB], [https://www.ebi.ac.uk/pdbsum/4hke PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4hke ProSAT]</span></td></tr>	+
	</table>		</table>
-	== Function ==
-	[[https://www.uniprot.org/uniprot/Q81VF4_BACAN Q81VF4_BACAN]] Toxic component of a toxin-antitoxin (TA) module (By similarity).[PIRNR:PIRNR033490]
-	<div style="background-color:#fffaf0;">
-	== Publication Abstract from PubMed ==
-	Bacillus anthracis MoxXT is a Type II proteic Toxin-Antitoxin (TA) module wherein MoxT is a ribonuclease that cleaves RNA specifically while MoxX interacts with MoxT and inhibits its activity. Disruption of the TA interaction has been proposed as a novel antibacterial strategy. Peptides, either based on antitoxin sequence or rationally designed, have previously been reported to disrupt the MoxXT interaction but cause a decrease in MoxT ribonuclease activity. In the present study, we report the crystal structure of MoxT, and the effect of several peptides in disrupting the MoxXT interaction as well as augmentation of MoxT ribonuclease activity by binding to MoxT in vitro. Docking studies on the peptides were carried out in order to explain the observed structure activity relationships. The peptides with ribonuclease augmentation activity possess a distinct structure and are proposed to bind to a distinct site on MoxT. The docking of the active peptides with MoxT showed that they possess an aromatic group that occupies a conserved hydrophobic pocket. Additionally, the peptides inducing high ribonuclease activity were anchored by a negatively charged group near a cluster of positively charged residues present near the pocket. Our study provides a structural basis and rationale for the observed properties of the peptides and may aid the development of small molecules to disrupt the TA interaction.
-
-	Structural basis of Bacillus anthracis MoxXT disruption and the modulation of MoxT ribonuclease activity by rationally designed peptides.,Verma S, Kumar S, Gupta VP, Gourinath S, Bhatnagar S, Bhatnagar R J Biomol Struct Dyn. 2014 Mar 21. PMID:24650157<ref>PMID:24650157</ref>
-
-	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	</div>
-	<div class="pdbe-citations 4hke" style="background-color:#fffaf0;"></div>
-	== References ==
-	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Bhatnagar, R]]	+	[[Category: Bhatnagar R]]
-	[[Category: Gourinath, S]]	+	[[Category: Gourinath S]]
-	[[Category: Kumar, S]]	+	[[Category: Kumar S]]
-	[[Category: Verma, S]]	+	[[Category: Verma S]]
-	~~[[Category: Ribonuclease fold]]~~	+
-	~~[[Category: Sh3 barrel]]~~	+
-	~~[[Category: Toxin]]~~	+
-	~~[[Category: Toxin protein~~]]	+

OCA at 05:02, 25 August 2022

OCA — Thu, 25 Aug 2022 05:02:08 GMT

←Older revision		Revision as of 05:02, 25 August 2022
Line 1:		Line 1:

	==Crystal Structure of MoxT of Bacillus anthracis==		==Crystal Structure of MoxT of Bacillus anthracis==
-	<StructureSection load='4hke' size='340' side='right' caption='[[4hke]], [[Resolution\|resolution]] 1.87Å' scene=''>	+	<StructureSection load='4hke' size='340' side='right'caption='[[4hke]], [[Resolution\|resolution]] 1.87Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4hke]] is a 2 chain structure ~~with sequence from [http://en.wikipedia.org/wiki/"bacillus_cereus_var._anthracis"_(cohn_1872)_smith_et_al._1946 "bacillus cereus var. anthracis" (cohn 1872) smith et al. 1946]~~. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HKE OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4HKE FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4hke]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HKE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4HKE FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>~~</td></tr>~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">BAS0240, BA_0254, GBAA_0254, pemK, PemK family transcriptional regulator ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1392 "Bacillus cereus var. anthracis" (Cohn 1872) Smith et al. 1946])</td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4hke FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4hke OCA], [https://pdbe.org/4hke PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4hke RCSB], [https://www.ebi.ac.uk/pdbsum/4hke PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4hke ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4hke FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4hke OCA], [~~http~~://pdbe.org/4hke PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4hke RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4hke PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4hke ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/Q81VF4_BACAN Q81VF4_BACAN]] Toxic component of a toxin-antitoxin (TA) module (By similarity).[PIRNR:PIRNR033490]	+	[[https://www.uniprot.org/uniprot/Q81VF4_BACAN Q81VF4_BACAN]] Toxic component of a toxin-antitoxin (TA) module (By similarity).[PIRNR:PIRNR033490]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 23:		Line 22:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Bhatnagar, R]]		[[Category: Bhatnagar, R]]
	[[Category: Gourinath, S]]		[[Category: Gourinath, S]]

OCA at 18:41, 4 August 2016

OCA — Thu, 04 Aug 2016 18:41:18 GMT

←Older revision		Revision as of 18:41, 4 August 2016
Line 1:		Line 1:
		+
	==Crystal Structure of MoxT of Bacillus anthracis==		==Crystal Structure of MoxT of Bacillus anthracis==
	<StructureSection load='4hke' size='340' side='right' caption='[[4hke]], [[Resolution\|resolution]] 1.87Å' scene=''>		<StructureSection load='4hke' size='340' side='right' caption='[[4hke]], [[Resolution\|resolution]] 1.87Å' scene=''>
Line 5:		Line 6:
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">BAS0240, BA_0254, GBAA_0254, pemK, PemK family transcriptional regulator ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1392 "Bacillus cereus var. anthracis" (Cohn 1872) Smith et al. 1946])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">BAS0240, BA_0254, GBAA_0254, pemK, PemK family transcriptional regulator ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1392 "Bacillus cereus var. anthracis" (Cohn 1872) Smith et al. 1946])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4hke FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4hke OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4hke RCSB], [http://www.ebi.ac.uk/pdbsum/4hke PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4hke FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4hke OCA], [http://pdbe.org/4hke PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4hke RCSB], [http://www.ebi.ac.uk/pdbsum/4hke PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4hke ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 17:		Line 18:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 4hke" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 12:01, 25 December 2014

OCA — Thu, 25 Dec 2014 12:01:27 GMT

←Older revision		Revision as of 12:01, 25 December 2014
Line 1:		Line 1:
-	~~{{STRUCTURE_4hke~~\| ~~PDB~~=4hke \| ~~SCENE~~= }}	+	==Crystal Structure of MoxT of Bacillus anthracis==
-	===~~Crystal Structure of MoxT of~~ Bacillus anthracis===	+	<StructureSection load='4hke' size='340' side='right' caption='[[4hke]], [[Resolution\|resolution]] 1.87Å' scene=''>
-	~~{{ABSTRACT_PUBMED_24650157}}~~	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[4hke]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_cereus_var._anthracis"_(cohn_1872)_smith_et_al._1946 "bacillus cereus var. anthracis" (cohn 1872) smith et al. 1946]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HKE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4HKE FirstGlance]. <br>
-	==Function==	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">BAS0240, BA_0254, GBAA_0254, pemK, PemK family transcriptional regulator ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1392 "Bacillus cereus var. anthracis" (Cohn 1872) Smith et al. 1946])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4hke FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4hke OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4hke RCSB], [http://www.ebi.ac.uk/pdbsum/4hke PDBsum]</span></td></tr>
		+	</table>
		+	== Function ==
	[[http://www.uniprot.org/uniprot/Q81VF4_BACAN Q81VF4_BACAN]] Toxic component of a toxin-antitoxin (TA) module (By similarity).[PIRNR:PIRNR033490]		[[http://www.uniprot.org/uniprot/Q81VF4_BACAN Q81VF4_BACAN]] Toxic component of a toxin-antitoxin (TA) module (By similarity).[PIRNR:PIRNR033490]
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Bacillus anthracis MoxXT is a Type II proteic Toxin-Antitoxin (TA) module wherein MoxT is a ribonuclease that cleaves RNA specifically while MoxX interacts with MoxT and inhibits its activity. Disruption of the TA interaction has been proposed as a novel antibacterial strategy. Peptides, either based on antitoxin sequence or rationally designed, have previously been reported to disrupt the MoxXT interaction but cause a decrease in MoxT ribonuclease activity. In the present study, we report the crystal structure of MoxT, and the effect of several peptides in disrupting the MoxXT interaction as well as augmentation of MoxT ribonuclease activity by binding to MoxT in vitro. Docking studies on the peptides were carried out in order to explain the observed structure activity relationships. The peptides with ribonuclease augmentation activity possess a distinct structure and are proposed to bind to a distinct site on MoxT. The docking of the active peptides with MoxT showed that they possess an aromatic group that occupies a conserved hydrophobic pocket. Additionally, the peptides inducing high ribonuclease activity were anchored by a negatively charged group near a cluster of positively charged residues present near the pocket. Our study provides a structural basis and rationale for the observed properties of the peptides and may aid the development of small molecules to disrupt the TA interaction.

-	~~==About this Structure==~~	+	Structural basis of Bacillus anthracis MoxXT disruption and the modulation of MoxT ribonuclease activity by rationally designed peptides.,Verma S, Kumar S, Gupta VP, Gourinath S, Bhatnagar S, Bhatnagar R J Biomol Struct Dyn. 2014 Mar 21. PMID:24650157<ref>PMID:24650157</ref>
-	~~[[4hke]] is a 2 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/"bacillus_cereus_var~~.~~_anthracis"_(cohn_1872)_smith_et_al._1946 "bacillus cereus var. anthracis" (cohn 1872) smith et al. 1946]. Full crystallographic information is available from [http~~:/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=4HKE OCA].~~	+

-	==~~Reference~~==	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	~~<ref group="xtra">PMID:024650157</ref>~~<references ~~group="xtra"~~/><~~references~~/>	+	</div>
-	[[Category: Bhatnagar, R.]]	+	== References ==
-	[[Category: Gourinath, S.]]	+	<references/>
-	[[Category: Kumar, S.]]	+	__TOC__
-	[[Category: Verma, S.]]	+	</StructureSection>
		+	[[Category: Bhatnagar, R]]
		+	[[Category: Gourinath, S]]
		+	[[Category: Kumar, S]]
		+	[[Category: Verma, S]]
	[[Category: Ribonuclease fold]]		[[Category: Ribonuclease fold]]
	[[Category: Sh3 barrel]]		[[Category: Sh3 barrel]]
	[[Category: Toxin]]		[[Category: Toxin]]
	[[Category: Toxin protein]]		[[Category: Toxin protein]]

OCA at 07:42, 2 April 2014

OCA — Wed, 02 Apr 2014 07:42:30 GMT

←Older revision		Revision as of 07:42, 2 April 2014
Line 1:		Line 1:
	{{STRUCTURE_4hke\| PDB=4hke \| SCENE= }}		{{STRUCTURE_4hke\| PDB=4hke \| SCENE= }}
	===Crystal Structure of MoxT of Bacillus anthracis===		===Crystal Structure of MoxT of Bacillus anthracis===
		+	{{ABSTRACT_PUBMED_24650157}}

	==Function==		==Function==
Line 6:		Line 7:

	==About this Structure==		==About this Structure==
-	[[4hke]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HKE OCA].	+	[[4hke]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_cereus_var._anthracis"_(cohn_1872)_smith_et_al._1946 "bacillus cereus var. anthracis" (cohn 1872) smith et al. 1946]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HKE OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:024650157</ref><references group="xtra"/><references/>
	[[Category: Bhatnagar, R.]]		[[Category: Bhatnagar, R.]]
	[[Category: Gourinath, S.]]		[[Category: Gourinath, S.]]

OCA at 08:26, 13 November 2013

OCA — Wed, 13 Nov 2013 08:26:48 GMT

←Older revision		Revision as of 08:26, 13 November 2013
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	{{STRUCTURE_4hke\| PDB=4hke \| SCENE= }}
		+	===Crystal Structure of MoxT of Bacillus anthracis===

-	~~The entry 4hke is ON HOLD until Paper Publication~~	+	==Function==
		+	[[http://www.uniprot.org/uniprot/Q81VF4_BACAN Q81VF4_BACAN]] Toxic component of a toxin-antitoxin (TA) module (By similarity).[PIRNR:PIRNR033490]

-	~~Authors~~: ~~Verma~~, S., Kumar, S.~~, Gourinath~~, S.~~, Bhatnagar, R.~~	+	==About this Structure==
-		+	[[4hke]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HKE OCA].
-	~~Description~~: ~~Crystal structure of toxin pemK from Bacillus anthracis sterne~~	+	[[Category: Bhatnagar, R.]]
		+	[[Category: Gourinath, S.]]
		+	[[Category: Kumar, S.]]
		+	[[Category: Verma, S.]]
		+	[[Category: Ribonuclease fold]]
		+	[[Category: Sh3 barrel]]
		+	[[Category: Toxin]]
		+	[[Category: Toxin protein]]

OCA at 08:40, 31 October 2012

OCA — Wed, 31 Oct 2012 08:40:15 GMT

←Older revision		Revision as of 08:40, 31 October 2012
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 4hke is ON HOLD	+	The entry 4hke is ON HOLD until Paper Publication

-	Authors: Verma, S., Kumar, S., ~~Samudrala~~, G., Bhatnagar, R.	+	Authors: Verma, S., Kumar, S., Gourinath, S., Bhatnagar, R.

	Description: Crystal structure of toxin pemK from Bacillus anthracis sterne		Description: Crystal structure of toxin pemK from Bacillus anthracis sterne

OCA: Protected "4hke" [edit=sysop:move=sysop]

OCA — Wed, 24 Oct 2012 07:12:54 GMT

Protected "4hke" [edit=sysop:move=sysop]

←Older revision

Revision as of 07:12, 24 October 2012

OCA: New page: '''Unreleased structure''' The entry 4hke is ON HOLD Authors: Verma, S., Kumar, S., Samudrala, G., Bhatnagar, R. Description: Crystal structure of toxin pemK from Bacillus anthracis st...

OCA — Wed, 24 Oct 2012 07:12:53 GMT

New page: '''Unreleased structure''' The entry 4hke is ON HOLD Authors: Verma, S., Kumar, S., Samudrala, G., Bhatnagar, R. Description: Crystal structure of toxin pemK from Bacillus anthracis st...

New page

'''Unreleased structure'''

The entry 4hke is ON HOLD

Authors: Verma, S., Kumar, S., Samudrala, G., Bhatnagar, R.

Description: Crystal structure of toxin pemK from Bacillus anthracis sterne