4hug - Revision history

OCA at 15:11, 20 September 2023

OCA — Wed, 20 Sep 2023 15:11:13 GMT

←Older revision		Revision as of 15:11, 20 September 2023
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4hug]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Alkalihalobacillus_halodurans_C-125 Alkalihalobacillus halodurans C-125]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HUG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4HUG FirstGlance]. <br>		<table><tr><td colspan='2'>[[4hug]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Alkalihalobacillus_halodurans_C-125 Alkalihalobacillus halodurans C-125]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HUG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4HUG FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=UCL:5-CHLORO-2-DEOXYURIDINE+5-(DIHYDROGEN+PHOSPHATE)'>UCL</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.64Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=UCL:5-CHLORO-2-DEOXYURIDINE+5-(DIHYDROGEN+PHOSPHATE)'>UCL</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4hug FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4hug OCA], [https://pdbe.org/4hug PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4hug RCSB], [https://www.ebi.ac.uk/pdbsum/4hug PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4hug ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4hug FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4hug OCA], [https://pdbe.org/4hug PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4hug RCSB], [https://www.ebi.ac.uk/pdbsum/4hug PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4hug ProSAT]</span></td></tr>
	</table>		</table>

OCA at 08:15, 9 November 2022

OCA — Wed, 09 Nov 2022 08:15:50 GMT

←Older revision		Revision as of 08:15, 9 November 2022
Line 1:		Line 1:

	==Structure of 5-chlorouracil modified A:U base pairs==		==Structure of 5-chlorouracil modified A:U base pairs==
-	<StructureSection load='4hug' size='340' side='right' caption='[[4hug]], [[Resolution\|resolution]] 1.64Å' scene=''>	+	<StructureSection load='4hug' size='340' side='right'caption='[[4hug]], [[Resolution\|resolution]] 1.64Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4hug]] is a 6 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Bachd Bachd~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HUG OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4HUG FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4hug]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Alkalihalobacillus_halodurans_C-125 Alkalihalobacillus halodurans C-125]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HUG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4HUG FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>~~</td></tr>~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=UCL:5-CHLORO-2-DEOXYURIDINE+5-(DIHYDROGEN+PHOSPHATE)'>UCL</scene></td></tr>
-	~~<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat">~~<scene name='pdbligand=UCL:5-CHLORO-2-DEOXYURIDINE+5-(DIHYDROGEN+PHOSPHATE)'>UCL</scene~~></td></tr>~~	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4hug FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4hug OCA], [https://pdbe.org/4hug PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4hug RCSB], [https://www.ebi.ac.uk/pdbsum/4hug PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4hug ProSAT]</span></td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4htu\|4htu]], [[4hue\|4hue]], [[4huf\|4huf]]</td></tr>~~	+
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">rnhA, BH0863 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=272558 BACHD])</td></tr>	+
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Ribonuclease_H Ribonuclease H], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.26.4 3.1.26.4] </span></td></tr>	+
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4hug FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4hug OCA], [~~http~~://pdbe.org/4hug PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4hug RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4hug PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4hug ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/~~RNH1_BACHD RNH1_BACHD]~~] Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.	+	[https://www.uniprot.org/uniprot/RNH1_HALH5 RNH1_HALH5] Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.<ref>PMID:15989951</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 24:		Line 20:

	==See Also==		==See Also==
-	*[[Ribonuclease\|Ribonuclease]]	+	*[[Ribonuclease 3D structures\|Ribonuclease 3D structures]]
-	*[[Temp\|Temp]]	+
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Bachd~~]]	+	[[Category: Alkalihalobacillus halodurans C-125]]
-	[[Category: ~~Ribonuclease H~~]]	+	[[Category: Large Structures]]
-	[[Category: Egli, M]]	+	[[Category: Egli M]]
-	[[Category: Patra, A]]	+	[[Category: Patra A]]
-	~~[[Category: 5-chloro-2'-deoxyuridine]]~~	+
-	~~[[Category: Double helix]]~~	+
-	~~[[Category: Hydrolase-dna complex]]~~	+
-	~~[[Category: W-c base pair]]~~	+
-	~~[[Category: Watson-crick base pairing pattern]]~~	+
-	~~[[Category: Wobble base pair~~]]	+

OCA at 18:25, 5 August 2016

OCA — Fri, 05 Aug 2016 18:25:24 GMT

←Older revision		Revision as of 18:25, 5 August 2016
Line 1:		Line 1:
		+
	==Structure of 5-chlorouracil modified A:U base pairs==		==Structure of 5-chlorouracil modified A:U base pairs==
	<StructureSection load='4hug' size='340' side='right' caption='[[4hug]], [[Resolution\|resolution]] 1.64Å' scene=''>		<StructureSection load='4hug' size='340' side='right' caption='[[4hug]], [[Resolution\|resolution]] 1.64Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4hug]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Bacillus_halodurans_c-125 Bacillus halodurans c-125~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HUG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4HUG FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4hug]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Bachd Bachd]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HUG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4HUG FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=UCL:5-CHLORO-2-DEOXYURIDINE+5-(DIHYDROGEN+PHOSPHATE)'>UCL</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=UCL:5-CHLORO-2-DEOXYURIDINE+5-(DIHYDROGEN+PHOSPHATE)'>UCL</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4htu\|4htu]], [[4hue\|4hue]], [[4huf\|4huf]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4htu\|4htu]], [[4hue\|4hue]], [[4huf\|4huf]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">rnhA, BH0863 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=272558 ~~Bacillus halodurans C-125~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">rnhA, BH0863 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=272558 BACHD])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Ribonuclease_H Ribonuclease H], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.26.4 3.1.26.4] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Ribonuclease_H Ribonuclease H], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.26.4 3.1.26.4] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4hug FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4hug OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4hug RCSB], [http://www.ebi.ac.uk/pdbsum/4hug PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4hug FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4hug OCA], [http://pdbe.org/4hug PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4hug RCSB], [http://www.ebi.ac.uk/pdbsum/4hug PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4hug ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 20:		Line 21:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 4hug" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
	*[[Ribonuclease\|Ribonuclease]]		*[[Ribonuclease\|Ribonuclease]]
	*[[Temp\|Temp]]		*[[Temp\|Temp]]
-	*[[User:Jaime.Prilusky/Test/tree\|User:Jaime.Prilusky/Test/tree]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Bacillus halodurans c-125~~]]	+	[[Category: Bachd]]
	[[Category: Ribonuclease H]]		[[Category: Ribonuclease H]]
	[[Category: Egli, M]]		[[Category: Egli, M]]

OCA at 20:57, 25 December 2014

OCA — Thu, 25 Dec 2014 20:57:07 GMT

←Older revision		Revision as of 20:57, 25 December 2014
Line 1:		Line 1:
-	~~{{STRUCTURE_4hug\| PDB=4hug \| SCENE= }}~~	+	==Structure of 5-chlorouracil modified A:U base pairs==
-	===Structure of 5-chlorouracil modified A:U base pairs===	+	<StructureSection load='4hug' size='340' side='right' caption='[[4hug]], [[Resolution\|resolution]] 1.64Å' scene=''>
-	~~{{ABSTRACT_PUBMED_23275540}}~~	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[4hug]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_halodurans_c-125 Bacillus halodurans c-125]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HUG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4HUG FirstGlance]. <br>
-	==Function==	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
		+	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=UCL:5-CHLORO-2-DEOXYURIDINE+5-(DIHYDROGEN+PHOSPHATE)'>UCL</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4htu\|4htu]], [[4hue\|4hue]], [[4huf\|4huf]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">rnhA, BH0863 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=272558 Bacillus halodurans C-125])</td></tr>
		+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Ribonuclease_H Ribonuclease H], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.26.4 3.1.26.4] </span></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4hug FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4hug OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4hug RCSB], [http://www.ebi.ac.uk/pdbsum/4hug PDBsum]</span></td></tr>
		+	</table>
		+	== Function ==
	[[http://www.uniprot.org/uniprot/RNH1_BACHD RNH1_BACHD]] Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.		[[http://www.uniprot.org/uniprot/RNH1_BACHD RNH1_BACHD]] Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The thymine analog 5-chlorouridine, first reported in the 1950s as anti-tumor agent, is known as an effective mutagen, clastogen and toxicant as well as an effective inducer of sister-chromatid exchange. Recently, the first microorganism with a chemically different genome was reported; the selected Escherichia coli strain relies on the four building blocks 5-chloro-2'-deoxyuridine (ClU), A, C and G instead of the standard T, A, C, G alphabet [Marliere,P., Patrouix,J., Doring,V., Herdewijn,P., Tricot,S., Cruveiller,S., Bouzon,M. and Mutzel,R. (2011) Chemical evolution of a bacterium's genome. Angew. Chem. Int. Ed., 50, 7109-7114]. The residual fraction of T in the DNA of adapted bacteria was <2% and the switch from T to ClU was accompanied by a massive number of mutations, including >1500 A to G or G to A transitions in a culture. The former is most likely due to wobble base pairing between ClU and G, which may be more common for ClU than T. To identify potential changes in the geometries of base pairs and duplexes as a result of replacement of T by ClU, we determined four crystal structures of a B-form DNA dodecamer duplex containing ClU:A or ClU:G base pairs. The structures reveal nearly identical geometries of these pairs compared with T:A or T:G, respectively, and no consequences for stability and cleavage by an endonuclease (EcoRI). The lack of significant changes in the geometry of ClU:A and ClU:G base pairs relative to the corresponding native pairs is consistent with the sustained unlimited self-reproduction of E. coli strains with virtually complete T-->ClU genome substitution.
		+
		+	Structure, stability and function of 5-chlorouracil modified A:U and G:U base pairs.,Patra A, Harp J, Pallan PS, Zhao L, Abramov M, Herdewijn P, Egli M Nucleic Acids Res. 2012 Dec 28. PMID:23275540<ref>PMID:23275540</ref>

-	~~==About this Structure==~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	~~[[4hug]] is~~ a ~~6 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Bacillus_halodurans_c-125 Bacillus halodurans c-125]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=4HUG OCA].~~	+	</div>

	==See Also==		==See Also==
	*[[Ribonuclease\|Ribonuclease]]		*[[Ribonuclease\|Ribonuclease]]
		+	*[[Temp\|Temp]]
		+	*[[User:Jaime.Prilusky/Test/tree\|User:Jaime.Prilusky/Test/tree]]
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
	[[Category: Bacillus halodurans c-125]]		[[Category: Bacillus halodurans c-125]]
	[[Category: Ribonuclease H]]		[[Category: Ribonuclease H]]
-	[[Category: Egli, M.]]	+	[[Category: Egli, M]]
-	[[Category: Patra, A.]]	+	[[Category: Patra, A]]
	[[Category: 5-chloro-2'-deoxyuridine]]		[[Category: 5-chloro-2'-deoxyuridine]]
	[[Category: Double helix]]		[[Category: Double helix]]

OCA at 07:47, 27 March 2013

OCA — Wed, 27 Mar 2013 07:47:28 GMT

←Older revision		Revision as of 07:47, 27 March 2013
Line 1:		Line 1:
-	[[Image:4hug.png\|left\|200px]]
-
	{{STRUCTURE_4hug\| PDB=4hug \| SCENE= }}		{{STRUCTURE_4hug\| PDB=4hug \| SCENE= }}
-
	===Structure of 5-chlorouracil modified A:U base pairs===		===Structure of 5-chlorouracil modified A:U base pairs===
		+	{{ABSTRACT_PUBMED_23275540}}

-	~~{{ABSTRACT_PUBMED_23275540}}~~	+	==Function==
		+	[[http://www.uniprot.org/uniprot/RNH1_BACHD RNH1_BACHD]] Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.

	==About this Structure==		==About this Structure==

OCA at 09:29, 13 February 2013

OCA — Wed, 13 Feb 2013 09:29:23 GMT

←Older revision		Revision as of 09:29, 13 February 2013
Line 1:		Line 1:
-	[[Image:4hug.~~jpg~~\|left\|200px]]	+	[[Image:4hug.png\|left\|200px]]

	{{STRUCTURE_4hug\| PDB=4hug \| SCENE= }}		{{STRUCTURE_4hug\| PDB=4hug \| SCENE= }}
Line 5:		Line 5:
	===Structure of 5-chlorouracil modified A:U base pairs===		===Structure of 5-chlorouracil modified A:U base pairs===

		+	{{ABSTRACT_PUBMED_23275540}}

	==About this Structure==		==About this Structure==
	[[4hug]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_halodurans_c-125 Bacillus halodurans c-125]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HUG OCA].		[[4hug]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_halodurans_c-125 Bacillus halodurans c-125]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HUG OCA].
		+
		+	==See Also==
		+	*[[Ribonuclease\|Ribonuclease]]
	[[Category: Bacillus halodurans c-125]]		[[Category: Bacillus halodurans c-125]]
	[[Category: Ribonuclease H]]		[[Category: Ribonuclease H]]

OCA at 11:38, 19 December 2012

OCA — Wed, 19 Dec 2012 11:38:42 GMT

←Older revision		Revision as of 11:38, 19 December 2012
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	[[Image:4hug.jpg\|left\|200px]]

-	~~The entry~~ 4hug ~~is ON HOLD~~ ~~until Paper Publication~~	+	{{STRUCTURE_4hug\| PDB=4hug \| SCENE= }}

-	~~Authors: Patra,~~ A~~., Egli, M.~~	+	===Structure of 5-chlorouracil modified A:U base pairs===

-	~~Description:~~ Structure ~~of 5~~-~~chlorouracil modified~~ A:U base ~~pairs~~	+
		+	==About this Structure==
		+	[[4hug]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_halodurans_c-125 Bacillus halodurans c-125]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HUG OCA].
		+	[[Category: Bacillus halodurans c-125]]
		+	[[Category: Ribonuclease H]]
		+	[[Category: Egli, M.]]
		+	[[Category: Patra, A.]]
		+	[[Category: 5-chloro-2'-deoxyuridine]]
		+	[[Category: Double helix]]
		+	[[Category: Hydrolase-dna complex]]
		+	[[Category: W-c base pair]]
		+	[[Category: Watson-crick base pairing pattern]]
		+	[[Category: Wobble base pair]]

OCA at 20:45, 12 December 2012

OCA — Wed, 12 Dec 2012 20:45:07 GMT

←Older revision		Revision as of 20:45, 12 December 2012
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 4hug is ON HOLD	+	The entry 4hug is ON HOLD until Paper Publication

	Authors: Patra, A., Egli, M.		Authors: Patra, A., Egli, M.

	Description: Structure of 5-chlorouracil modified A:U base pairs		Description: Structure of 5-chlorouracil modified A:U base pairs

OCA: Protected "4hug" [edit=sysop:move=sysop]

OCA — Wed, 14 Nov 2012 06:19:05 GMT

Protected "4hug" [edit=sysop:move=sysop]

←Older revision

Revision as of 06:19, 14 November 2012

OCA: New page: '''Unreleased structure''' The entry 4hug is ON HOLD Authors: Patra, A., Egli, M. Description: Structure of 5-chlorouracil modified A:U base pairs

OCA — Wed, 14 Nov 2012 06:19:04 GMT

New page: '''Unreleased structure''' The entry 4hug is ON HOLD Authors: Patra, A., Egli, M. Description: Structure of 5-chlorouracil modified A:U base pairs

New page

'''Unreleased structure'''

The entry 4hug is ON HOLD

Authors: Patra, A., Egli, M.

Description: Structure of 5-chlorouracil modified A:U base pairs